Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss

byNYU Langone HealthCredit: CC0 Public DomainA cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.The study, led by re

Updated on: January 07,2024 20

Study in mice shows blocking abnormal stem cell signal during aging lessens related bone loss

byNYU Langone HealthCredit: CC0 Public DomainA cellular signal essential to the development of the skeleton increases during aging to weaken bones, finds a new study in mice.The study, led by re

Updated on:January 07,2024 20

CD36 regulation by CARD9 and Epsin: Novel therapeutic targets for atherosclerosis

Updated on: April 30,2024 0

CD36 regulation by CARD9 and Epsin: Novel therapeutic targets for atherosclerosis

Updated on:April 30,2024 0

AI-based analysis identifies two plant extracts with potential as GLP-1 agonist weight loss pills

by European Association for the Study of ObesityCredit: AI-generated imageTwo plant compounds with potential as GLP-1 agonist weight loss pills have been identified in an AI (artificial intelligence)-

Updated on: March 28,2024 0

AI-based analysis identifies two plant extracts with potential as GLP-1 agonist weight loss pills

by European Association for the Study of ObesityCredit: AI-generated imageTwo plant compounds with potential as GLP-1 agonist weight loss pills have been identified in an AI (artificial intelligence)-

Updated on:March 28,2024 0

Light-activated muscle grafts show promise in aiding muscle recovery post-trauma

byMassachusetts Institute of TechnologyRitu Raman (center), the d’Arbeloff Career Development Assistant Professor of Mechanical Engineering, speaks with students in her lab. Credit: Tony Pulsone

Updated on: January 04,2024 14

Light-activated muscle grafts show promise in aiding muscle recovery post-trauma

byMassachusetts Institute of TechnologyRitu Raman (center), the d’Arbeloff Career Development Assistant Professor of Mechanical Engineering, speaks with students in her lab. Credit: Tony Pulsone

Updated on:January 04,2024 14

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats

Updated on: December 30,2023 5

Psilocybin found to reduce chronic pain in rats

by Bob Yirka , Medical XpressEffect of intravenous psilocybin on mechanical hypersensitivity and thermal hyperalgesia. (A) Schematic illustrating the design and timeline of the experiments. (B,C) Rats

Updated on:December 30,2023 5

Study finds ketamine effects outlast half-life by getting trapped in NMDA receptors

by Justin Jackson , Medical XpressSingle injection of ketamine no longer causes antidepressant effects on day 3 or day 7. Credit:Nature(2023). DOI: 10.1038/s41586-023-06624-1Researchers at

Updated on: January 10,2024 5

Study finds ketamine effects outlast half-life by getting trapped in NMDA receptors

by Justin Jackson , Medical XpressSingle injection of ketamine no longer causes antidepressant effects on day 3 or day 7. Credit:Nature(2023). DOI: 10.1038/s41586-023-06624-1Researchers at

Updated on:January 10,2024 5

Researchers are building a cellular map of the musculoskeletal system

byUniversity of OxfordGeneralized workflow for generating a single-cell musculoskeletal atlas. To generate a single-cell atlas of the musculoskeletal system, samples are first acquired from musc

Updated on: January 05,2024 14

Researchers are building a cellular map of the musculoskeletal system

byUniversity of OxfordGeneralized workflow for generating a single-cell musculoskeletal atlas. To generate a single-cell atlas of the musculoskeletal system, samples are first acquired from musc

Updated on:January 05,2024 14

New insight into old IBD drug could improve treatments

by Jim Schnabel,Cornell UniversityGraphical Abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101431Although it is one of the oldest medications used to treat pa

Updated on: March 30,2024 13

New insight into old IBD drug could improve treatments

by Jim Schnabel,Cornell UniversityGraphical Abstract. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101431Although it is one of the oldest medications used to treat pa

Updated on:March 30,2024 13

Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans

by Jim Fessenden, UMass Chan Medical SchoolB12produced by gut bacteria suppresses the hyperactive behavior of unc-2(gof) mutants. Credit:Nature Cell Biology(2024). DOI: 10.1038/s4155

Updated on: January 09,2024 12

Researchers identify molecular link between gut bacteria and excitatory brain signaling in C. elegans

by Jim Fessenden, UMass Chan Medical SchoolB12produced by gut bacteria suppresses the hyperactive behavior of unc-2(gof) mutants. Credit:Nature Cell Biology(2024). DOI: 10.1038/s4155

Updated on:January 09,2024 12

UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of medical researchers with affiliations to British multinational pharmaceutical and biotechnology company GlaxoSmithKline (GSK) ha

Updated on: March 21,2024 19

UTI drug gepotidacin performs well in clinical trials compared to nitrofurantoin

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainA team of medical researchers with affiliations to British multinational pharmaceutical and biotechnology company GlaxoSmithKline (GSK) ha

Updated on:March 21,2024 19

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on: April 23,2024 14

Drug candidate granted FDA orphan drug status for pancreatic cancer

by Roswell Park Comprehensive Cancer CenterCredit:Journal of Medicinal Chemistry(2023). DOI: 10.1021/acs.jmedchem.3c01589The U.S. Food and Drug Administration (FDA) has awarded Orphan Drug

Updated on:April 23,2024 14

Researchers identify a potential target for reversing poor metabolic traits

by Brandon Chase,Massachusetts General HospitalGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.11.010During oxidative stress, excess production of reactive

Updated on: December 26,2023 10

Researchers identify a potential target for reversing poor metabolic traits

by Brandon Chase,Massachusetts General HospitalGraphical abstract. Credit:Cell Metabolism(2023). DOI: 10.1016/j.cmet.2023.11.010During oxidative stress, excess production of reactive

Updated on:December 26,2023 10