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Medical research
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Cannabis use linked to increase in heart attack and stroke risk

Cannabis use linked to increase in heart attack and stroke risk

FEBRUARY 28, 2024 Editors' notesbyAmerican Heart AssociationCredit: Unsplash/CC0 Public DomainAn analysis of 430,000 adults in the U.S. found that using cannabis, most commonly through smoki

Cannabis use linked to increase in heart attack and stroke risk

FEBRUARY 28, 2024 Editors' notesbyAmerican Heart AssociationCredit: Unsplash/CC0 Public DomainAn analysis of 430,000 adults in the U.S. found that using cannabis, most commonly through smoki
New study reveals unexpected consequences of CRISPR-Cas9 gene editing

New study reveals unexpected consequences of CRISPR-Cas9 gene editing

byKarolinska InstitutetSchematic illustration displays the workflow for determining the frequency of the genomic deletion of the PAPSS2-PTEN locus and associated cellular consequences in single-

New study reveals unexpected consequences of CRISPR-Cas9 gene editing

byKarolinska InstitutetSchematic illustration displays the workflow for determining the frequency of the genomic deletion of the PAPSS2-PTEN locus and associated cellular consequences in single-
Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind

Scientists reveal new TEV-mediated αPD-L1-specific therapy resistance mechanism

by Zhejiang UniversityTEV PD-L1 competes with PD-L1 on tumor cells to bind αPD-L1.a,bMC38-EVs and PC3-EVs (1 μg) (a) or MC38 and PC3 cells (1 × 105) (b) were coincubated with the ind
Experimental antibiotic treatment for Lyme disease heads for human safety trials

Experimental antibiotic treatment for Lyme disease heads for human safety trials

FEBRUARY 29, 2024by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Pixabay/CC0 Public DomainHuman safety trials of a novel antibiotic treatment for Lyme disease developed by Northeaste

Experimental antibiotic treatment for Lyme disease heads for human safety trials

FEBRUARY 29, 2024by Cynthia McCormick Hibbert,Northeastern UniversityCredit: Pixabay/CC0 Public DomainHuman safety trials of a novel antibiotic treatment for Lyme disease developed by Northeaste
Plastic particles harm gut health and immunity in mice, study shows

Plastic particles harm gut health and immunity in mice, study shows

by Zhang Nannan,Chinese Academy of SciencesEffect of PS-MNPs on the intestinal structure of mice. Representative images of H&E staining of mouse intestinal tissue. (A) Intestine of mice afte

Plastic particles harm gut health and immunity in mice, study shows

by Zhang Nannan,Chinese Academy of SciencesEffect of PS-MNPs on the intestinal structure of mice. Representative images of H&E staining of mouse intestinal tissue. (A) Intestine of mice afte
New study lists potentially dangerous drugs in Australian health care

New study lists potentially dangerous drugs in Australian health care

by RMIT University'Potentially inappropriate medicines' (PIMs) include ibuprofen and codeine - pictured. Credit: RMIT University / Ant BragagliaResearchers have developed an Australian-fi

New study lists potentially dangerous drugs in Australian health care

by RMIT University'Potentially inappropriate medicines' (PIMs) include ibuprofen and codeine - pictured. Credit: RMIT University / Ant BragagliaResearchers have developed an Australian-fi
Anesthesia technology precisely controls unconsciousness in animal tests

Anesthesia technology precisely controls unconsciousness in animal tests

byMassachusetts Institute of TechnologySchematic of the propofol-based CLAD system for control of unconsciousness in an NHP. The user sets the target level of the marker of unconsciousness (MOU)

Anesthesia technology precisely controls unconsciousness in animal tests

byMassachusetts Institute of TechnologySchematic of the propofol-based CLAD system for control of unconsciousness in an NHP. The user sets the target level of the marker of unconsciousness (MOU)
Study finds tafenoquine is a cost-effective treatment option for malaria

Study finds tafenoquine is a cost-effective treatment option for malaria

by Menzies School of Health ResearchMap of incremental cost-effectiveness ratios (ICERs) in each malaria-endemic municipality for Scenario 1 (tafenoquine for adults, primaquine adherence 66.7%),

Study finds tafenoquine is a cost-effective treatment option for malaria

by Menzies School of Health ResearchMap of incremental cost-effectiveness ratios (ICERs) in each malaria-endemic municipality for Scenario 1 (tafenoquine for adults, primaquine adherence 66.7%),
Predicting correct dosage may improve success of drug repurposing

Predicting correct dosage may improve success of drug repurposing

by Sarah Small,Pennsylvania State UniversityCredit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101227Before a drug can be used to treat a disease, it must go through a leng

Predicting correct dosage may improve success of drug repurposing

by Sarah Small,Pennsylvania State UniversityCredit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101227Before a drug can be used to treat a disease, it must go through a leng
Dos and don'ts developed for direct oral anticoagulants

Dos and don'ts developed for direct oral anticoagulants

by Brigham and Women’s HospitalCentral Illustration. Credit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.038Direct oral anticoagulants (DOACs) are

Dos and don'ts developed for direct oral anticoagulants

by Brigham and Women’s HospitalCentral Illustration. Credit:Journal of the American College of Cardiology(2024). DOI: 10.1016/j.jacc.2023.10.038Direct oral anticoagulants (DOACs) are