Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on: April 29,2024 15

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on:April 29,2024 15

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on: April 29,2024 14

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on:April 29,2024 14

Significant correlation found between vitreous human biomarkers and Alzheimer's disease

by Boston Medical CenterBoxplots of vitreous fluid biomarkers levels of total Tau, by study groups, compared using Kruskal-Wallis rank sum test withpvalues adjusted for multiple compa

Updated on: April 29,2024 18

Significant correlation found between vitreous human biomarkers and Alzheimer's disease

by Boston Medical CenterBoxplots of vitreous fluid biomarkers levels of total Tau, by study groups, compared using Kruskal-Wallis rank sum test withpvalues adjusted for multiple compa

Updated on:April 29,2024 18

Overlooked tau-RNA interaction may play key role in dementia

by University of WashingtonThis antibody staining experiment shows tau-RNA complexes that have been dyed green. The tau-RNA complex staining strongly resembles neurofibrillary tangles, a hallmark

Updated on: April 29,2024 12

Overlooked tau-RNA interaction may play key role in dementia

by University of WashingtonThis antibody staining experiment shows tau-RNA complexes that have been dyed green. The tau-RNA complex staining strongly resembles neurofibrillary tangles, a hallmark

Updated on:April 29,2024 12

Geraniol attenuates oxidative stress and cognitive impairment in mouse aging model

by Impact Journals LLCEffect of GNL on D-gal-induced cognitive impairment mice by using99mTc-HMPAO (brain) animal imaging. Credit:Aging(2024). DOI: 10.18632/aging.205677A new researc

Updated on: April 28,2024 0

Geraniol attenuates oxidative stress and cognitive impairment in mouse aging model

by Impact Journals LLCEffect of GNL on D-gal-induced cognitive impairment mice by using99mTc-HMPAO (brain) animal imaging. Credit:Aging(2024). DOI: 10.18632/aging.205677A new researc

Updated on:April 28,2024 0

Alzheimer's drug development pipeline: Positive results, new insight on biomarkers position 2024 as 'learning year'

by Steven Slivka, John Domol,University of Nevada, Las VegasDr. Jeffrey Cummings, research professor and director, Chambers-Grundy Center for Transformative Neuroscience at UNLV. Credit: Josh Ha

Updated on: April 28,2024 0

Alzheimer's drug development pipeline: Positive results, new insight on biomarkers position 2024 as 'learning year'

by Steven Slivka, John Domol,University of Nevada, Las VegasDr. Jeffrey Cummings, research professor and director, Chambers-Grundy Center for Transformative Neuroscience at UNLV. Credit: Josh Ha

Updated on:April 28,2024 0

How the inflamed brain becomes disconnected after a stroke

by Levi Gadye,University of California, San FranciscoThe brain’s neurons (yellow) connect with one another using a vast network of neural wires, called neurites. Credit: Swanson Lab/University o

Updated on: April 28,2024 0

How the inflamed brain becomes disconnected after a stroke

by Levi Gadye,University of California, San FranciscoThe brain’s neurons (yellow) connect with one another using a vast network of neural wires, called neurites. Credit: Swanson Lab/University o

Updated on:April 28,2024 0

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on: April 28,2024 0

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on:April 28,2024 0

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on: April 28,2024 0

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on:April 28,2024 0

After spinal cord injury, neurons wreak havoc on metabolism: Study finds common drug may prevent some of the effects

by Emily Caldwell,The Ohio State UniversityFluorescence image of sensory axons, in red, connecting with visceral white fat tissue seven days after a spinal cord injury in an adult mouse. Credit:

Updated on: April 28,2024 0

After spinal cord injury, neurons wreak havoc on metabolism: Study finds common drug may prevent some of the effects

by Emily Caldwell,The Ohio State UniversityFluorescence image of sensory axons, in red, connecting with visceral white fat tissue seven days after a spinal cord injury in an adult mouse. Credit:

Updated on:April 28,2024 0

Brain vesicles found to contain selectively packaged, full-length mRNA

by Sanford-Burnham PrebysThis portrait of extracellular vesicles was taken using confocal laser scanning microscopy. The membrane was stained with fluorescent dye. Image titled"Exosome

Updated on: April 28,2024 0

Brain vesicles found to contain selectively packaged, full-length mRNA

by Sanford-Burnham PrebysThis portrait of extracellular vesicles was taken using confocal laser scanning microscopy. The membrane was stained with fluorescent dye. Image titled"Exosome

Updated on:April 28,2024 0

Researchers map the spatio-temporal human brain dynamics of a visual image being recognized

by Rachel Gordon,Massachusetts Institute of TechnologyA team of MIT researchers found highly memorable images have stronger and sustained responses in ventro-occipital brain cortices, peaking at

Updated on: April 28,2024 0

Researchers map the spatio-temporal human brain dynamics of a visual image being recognized

by Rachel Gordon,Massachusetts Institute of TechnologyA team of MIT researchers found highly memorable images have stronger and sustained responses in ventro-occipital brain cortices, peaking at

Updated on:April 28,2024 0