Protein shapes matter in Alzheimer's research

by Allison Mills,Michigan Technological UniversityCellular toxicity, which is higher in amyloid amorphous aggregates, shows that small changes in protein folding chemistry can cause differences

Updated on: April 16,2024 12

Protein shapes matter in Alzheimer's research

by Allison Mills,Michigan Technological UniversityCellular toxicity, which is higher in amyloid amorphous aggregates, shows that small changes in protein folding chemistry can cause differences

Updated on:April 16,2024 12

Consistent gene changes in Alzheimer's disease across studies

by Society for NeuroscienceTop 20 up and down-regulated genes for late phase Alzheimer's disease. Credit: Zhuang et al.,eNeuro2019A comparison of mouse Alzheimer's disease mod

Updated on: April 16,2024 10

Consistent gene changes in Alzheimer's disease across studies

by Society for NeuroscienceTop 20 up and down-regulated genes for late phase Alzheimer's disease. Credit: Zhuang et al.,eNeuro2019A comparison of mouse Alzheimer's disease mod

Updated on:April 16,2024 10

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024 11

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024 11

Alzheimer's: Blood biomarker may help identify the disease ten years before symptoms start

by Caroline Graff and Charlotte Johansson,The ConversationCredit: AI-generated imageThough Alzheimer's disease affects more than55 million people worldwide, there's still no cure f

Updated on: April 16,2024 17

Alzheimer's: Blood biomarker may help identify the disease ten years before symptoms start

by Caroline Graff and Charlotte Johansson,The ConversationCredit: AI-generated imageThough Alzheimer's disease affects more than55 million people worldwide, there's still no cure f

Updated on:April 16,2024 17

Alzheimer's disease is composed of four distinct subtypes

by Lund UniversityCredit: Unsplash/CC0 Public DomainAlzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can no

Updated on: April 16,2024 12

Alzheimer's disease is composed of four distinct subtypes

by Lund UniversityCredit: Unsplash/CC0 Public DomainAlzheimer's disease is characterized by the abnormal accumulation and spread of the tau protein in the brain. An international study can no

Updated on:April 16,2024 12

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on: April 16,2024 20

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on:April 16,2024 20

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on: April 16,2024 12

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on:April 16,2024 12

Alzheimer's drug trial shows 'evidence of sustained improvement'

by University of AberdeenRelationship between steady-state plasma levels of hydromethylthionine and decline on the ADAS-Cog11scale over 65 weeks in 566 participants receiving hydromethylthi

Updated on: April 16,2024 18

Alzheimer's drug trial shows 'evidence of sustained improvement'

by University of AberdeenRelationship between steady-state plasma levels of hydromethylthionine and decline on the ADAS-Cog11scale over 65 weeks in 566 participants receiving hydromethylthi

Updated on:April 16,2024 18

Advances along the gut-liver-brain axis in Alzheimer's disease

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainFour new studies reported at the Alzheimer's Association International Conference (AAIC)

Updated on: April 16,2024 19

Advances along the gut-liver-brain axis in Alzheimer's disease

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainFour new studies reported at the Alzheimer's Association International Conference (AAIC)

Updated on:April 16,2024 19

Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on: April 16,2024 18

Alzheimer's drug donanemab has been hailed as a turning point. But what does it mean for people with the disease?

by Steve Macfarlane,The ConversationCredit: AI-generated imageTrial results of a new drug to treat Alzheimer's disease, donanemab, shows it canslow cognitive declineby 35%. The d

Updated on:April 16,2024 18

Alzheimer's drug gets FDA panel's backing, setting the stage for broader use

by Matthew PerroneThis Dec. 21, 2022, image provided by Eisai in January 2023 shows vials and packaging for their medication Leqembi. On Friday, June 9, 2023, health advisers backed the full approval

Updated on: April 16,2024 12

Alzheimer's drug gets FDA panel's backing, setting the stage for broader use

by Matthew PerroneThis Dec. 21, 2022, image provided by Eisai in January 2023 shows vials and packaging for their medication Leqembi. On Friday, June 9, 2023, health advisers backed the full approval

Updated on:April 16,2024 12

Alzheimer research: Noise-inducing neurons shut down memories

by German Center for Neurodegenerative DiseasesCredit: Public DomainNeurons that are responsible for new experiences interfere with the signals of neurons that contain memories and thereby distur

Updated on: April 16,2024 10

Alzheimer research: Noise-inducing neurons shut down memories

by German Center for Neurodegenerative DiseasesCredit: Public DomainNeurons that are responsible for new experiences interfere with the signals of neurons that contain memories and thereby distur

Updated on:April 16,2024 10