Alzheimer-linked enzyme complex 'buckles up' for safe trip through the cell

by VIB (the Flanders Institute for Biotechnology)Credit: Opabinia regalis, CC BY-SA 4.0A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protei

Updated on: April 10,2024 20

Alzheimer-linked enzyme complex 'buckles up' for safe trip through the cell

by VIB (the Flanders Institute for Biotechnology)Credit: Opabinia regalis, CC BY-SA 4.0A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protei

Updated on:April 10,2024 20

Changes in Alzheimer biomarkers tied to withdrawal of positive airway pressure for obstructive sleep apnea

For patients with severe obstructive sleep apnea (OSA), withdrawal of positive airway pressure (PAP) is associated with changes in plasma Alzheimer disease biomarkers, according to a study published o

Updated on: April 10,2024 17

Changes in Alzheimer biomarkers tied to withdrawal of positive airway pressure for obstructive sleep apnea

For patients with severe obstructive sleep apnea (OSA), withdrawal of positive airway pressure (PAP) is associated with changes in plasma Alzheimer disease biomarkers, according to a study published o

Updated on:April 10,2024 17

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on: April 10,2024 18

Alzheimer's: New study supports amyloid hypothesis but suggests alternative treatment

by Columbia UniversityCREB3L2-ATF4 up-regulation in β-amyloid pathology 5xFAD model. In vivo detection and quantification of CREB3L2-ATF4 dimers by PLA in the dentate gyrus of 10-week-old 5xFAD o

Updated on:April 10,2024 18

Alzheimer's disease might be a 'whole body' problem

by University of British ColumbiaPair of surgically joined mice. Credit: University of British ColumbiaAlzheimer's disease, the leading cause of dementia, has long been assumed to originate i

Updated on: April 10,2024 17

Alzheimer's disease might be a 'whole body' problem

by University of British ColumbiaPair of surgically joined mice. Credit: University of British ColumbiaAlzheimer's disease, the leading cause of dementia, has long been assumed to originate i

Updated on:April 10,2024 17

Alzheimer's vs. other dementias: What's the difference?

by Ann SchreiberImagine struggling to remember your loved ones, the places you've been or even your own name. The haunting reality of Alzheimer's disease and dementia is a terrifying prospect

Updated on: April 10,2024 14

Alzheimer's vs. other dementias: What's the difference?

by Ann SchreiberImagine struggling to remember your loved ones, the places you've been or even your own name. The haunting reality of Alzheimer's disease and dementia is a terrifying prospect

Updated on:April 10,2024 14

More hospital days seen with antipsychotic use in Alzheimer disease

(HealthDay)—Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics, according to a study recently p

Updated on: April 10,2024 17

More hospital days seen with antipsychotic use in Alzheimer disease

(HealthDay)—Alzheimer disease patients who initiate treatment with antipsychotic medications spend more days hospitalized than those who do not initiate antipsychotics, according to a study recently p

Updated on:April 10,2024 17

Alzheimer's disease—why insulin is a new suspect

by Christian Holscher,The ConversationCredit: AI-generated imageJohnson and Johnsonrecently announcedthat it was halting a clinical trial for a new Alzheimer's drug after safety

Updated on: April 10,2024 11

Alzheimer's disease—why insulin is a new suspect

by Christian Holscher,The ConversationCredit: AI-generated imageJohnson and Johnsonrecently announcedthat it was halting a clinical trial for a new Alzheimer's drug after safety

Updated on:April 10,2024 11

Can Alzheimer's be stopped years before it starts?

by Erica Rheinschild,University of Southern CaliforniaCredit: AI-generated imageResearchers at the Keck School of Medicine of USC are tackling the sixth-leading cause of death in the United Stat

Updated on: April 10,2024 10

Can Alzheimer's be stopped years before it starts?

by Erica Rheinschild,University of Southern CaliforniaCredit: AI-generated imageResearchers at the Keck School of Medicine of USC are tackling the sixth-leading cause of death in the United Stat

Updated on:April 10,2024 10

Alzheimer's and cardiovascular disease share common genetics in some patients

by University of California, San FranciscoCredit: CC0 Public DomainGenetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a

Updated on: April 10,2024 14

Alzheimer's and cardiovascular disease share common genetics in some patients

by University of California, San FranciscoCredit: CC0 Public DomainGenetics may predispose some people to both Alzheimer's disease and high levels of blood lipids such as cholesterol, a

Updated on:April 10,2024 14

Spread of tau protein measured in the brains of Alzheimer's patients

by Karolinska InstitutetThe images show tau deposits in the brain of a patient with early-stage Alzheimer’s disease. The warm colours indicate regions of heavy deposition and the difference in sp

Updated on: April 10,2024 12

Spread of tau protein measured in the brains of Alzheimer's patients

by Karolinska InstitutetThe images show tau deposits in the brain of a patient with early-stage Alzheimer’s disease. The warm colours indicate regions of heavy deposition and the difference in sp

Updated on:April 10,2024 12

Potential noninvasive treatment for Alzheimer's disease

by University of QueenslandCredit: University of QueenslandUltrasound can overcome some of the detrimental effects of aging and dementia without the need to cross the blood-brain barrier, researc

Updated on: April 10,2024 14

Potential noninvasive treatment for Alzheimer's disease

by University of QueenslandCredit: University of QueenslandUltrasound can overcome some of the detrimental effects of aging and dementia without the need to cross the blood-brain barrier, researc

Updated on:April 10,2024 14

Alzheimer's disease plasma biomarker contributes to postoperative delirium-like behavior in rodents

by Brandon Chase,Massachusetts General HospitalCredit: CC0 Public DomainTauopathy is one of the hallmarks of Alzheimer's disease (AD) pathogenesis, and the phosphorylation of Tau at threonin

Updated on: April 10,2024 12

Alzheimer's disease plasma biomarker contributes to postoperative delirium-like behavior in rodents

by Brandon Chase,Massachusetts General HospitalCredit: CC0 Public DomainTauopathy is one of the hallmarks of Alzheimer's disease (AD) pathogenesis, and the phosphorylation of Tau at threonin

Updated on:April 10,2024 12