Zebrafish discovery could speed testing of motor neuron disease and dementia treatments

by Georgia Gowing,Macquarie UniversityCredit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae112Tiny, transparent fish have made it possible for Macquarie University neuroscientis

Updated on: March 19,2024 15

Zebrafish discovery could speed testing of motor neuron disease and dementia treatments

by Georgia Gowing,Macquarie UniversityCredit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae112Tiny, transparent fish have made it possible for Macquarie University neuroscientis

Updated on:March 19,2024 15

How springing forward to daylight saving time could affect your health—and how to prepare

by Lauran NeergaardA selection of vintage clocks are displayed at Electric Time Company, Tuesday, Nov. 1, 2022, in Medfield, Mass. Most of America “springs forward” Sunday, March 10, 2024, for dayligh

Updated on: March 19,2024 12

How springing forward to daylight saving time could affect your health—and how to prepare

by Lauran NeergaardA selection of vintage clocks are displayed at Electric Time Company, Tuesday, Nov. 1, 2022, in Medfield, Mass. Most of America “springs forward” Sunday, March 10, 2024, for dayligh

Updated on:March 19,2024 12

Early clinical trial results show 'dramatic and rapid' regression of glioblastoma after next generation CAR-T therapy

by Mass General BrighamCredit: Unsplash/CC0 Public DomainA collaborative project to bring the promise of cell therapy to patients with a deadly form of brain cancer has shown dramatic results amo

Updated on: March 20,2024 13

Early clinical trial results show 'dramatic and rapid' regression of glioblastoma after next generation CAR-T therapy

by Mass General BrighamCredit: Unsplash/CC0 Public DomainA collaborative project to bring the promise of cell therapy to patients with a deadly form of brain cancer has shown dramatic results amo

Updated on:March 20,2024 13

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on: March 20,2024 17

Single-cell RNA-seq reveals transcriptomic modulation of Alzheimer's disease by activated protein C

by Impact Journals LLC(A) Representative images and quantification of Aβ stained with thioflavin S in the hippocampus and cortex of 5xFAD mice treated with or without APC. (B) Radial arm water maze te

Updated on:March 20,2024 17

Researchers identify gene involved in neuronal vulnerability in Alzheimer's disease

by Boston University School of MedicineCredit: CC0 Public DomainEarly stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cell

Updated on: March 20,2024 13

Researchers identify gene involved in neuronal vulnerability in Alzheimer's disease

by Boston University School of MedicineCredit: CC0 Public DomainEarly stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cell

Updated on:March 20,2024 13

Research reveals DNA-protecting gene's crucial role in brain disorders

by Jessica Stanley,University of AdelaideL–R: Microscopic images showing bright red spots on a cell, indicating an increase in detrimental RNA:DNA Hybrids. Second image shows cells with high DNA

Updated on: March 20,2024 13

Research reveals DNA-protecting gene's crucial role in brain disorders

by Jessica Stanley,University of AdelaideL–R: Microscopic images showing bright red spots on a cell, indicating an increase in detrimental RNA:DNA Hybrids. Second image shows cells with high DNA

Updated on:March 20,2024 13

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on: March 20,2024 13

Scientists use an innovative approach to provide relevant insights into a rare neurologic disorder

by Germans Trias i Pujol Research InstituteLong-read nanopore sequencing of the genomic region including theDAB1ATTTT/ATTTC repeat tract enriched by CRISPR/Cas9.aThe integrativ

Updated on:March 20,2024 13

First-of-its-kind super minigene to boost spinal muscular atrophy research

by Dave Roepke,Iowa State UniversityGraphical Abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkad1259Ravindra Singh has spent years studying a gene that, when missin

Updated on: March 20,2024 10

First-of-its-kind super minigene to boost spinal muscular atrophy research

by Dave Roepke,Iowa State UniversityGraphical Abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkad1259Ravindra Singh has spent years studying a gene that, when missin

Updated on:March 20,2024 10

FRYL gene variants linked to a new neurological disorder

by Texas Children's HospitalCredit: Unsplash/CC0 Public DomainA recent study from the lab of Dr. Hugo J. Bellen, distinguished service professor at Baylor College of Medicine and investigator

Updated on: March 20,2024 14

FRYL gene variants linked to a new neurological disorder

by Texas Children's HospitalCredit: Unsplash/CC0 Public DomainA recent study from the lab of Dr. Hugo J. Bellen, distinguished service professor at Baylor College of Medicine and investigator

Updated on:March 20,2024 14

Researchers identify mutation that alters Alzheimer's disease progression

by University of MalagaResearchers identify a mutation that alters Alzheimer's disease progression. The UMA coordinates this study, carried out by 100 multidisciplinary researchers from 50 di

Updated on: March 20,2024 19

Researchers identify mutation that alters Alzheimer's disease progression

by University of MalagaResearchers identify a mutation that alters Alzheimer's disease progression. The UMA coordinates this study, carried out by 100 multidisciplinary researchers from 50 di

Updated on:March 20,2024 19

Mutation provides insights into mechanisms of neurodegeneration in Parkinson's disease

by Olivia Dimmer,Northwestern UniversityVPS13C deficiency alters ER-lysosome and mitochondria-lysosome contact sites in iPSC-derived dopaminergic neurons. (A and B). Credit:Journal of Cell

Updated on: March 20,2024 16

Mutation provides insights into mechanisms of neurodegeneration in Parkinson's disease

by Olivia Dimmer,Northwestern UniversityVPS13C deficiency alters ER-lysosome and mitochondria-lysosome contact sites in iPSC-derived dopaminergic neurons. (A and B). Credit:Journal of Cell

Updated on:March 20,2024 16

High blood pressure's impact on white matter could be key to dementia prevention

by Heidi Douglass,University of New South WalesCredit: Pixabay/CC0 Public DomainA study from the Center for Healthy Brain Aging (CHeBA) provides compelling evidence for clinical practice to dire

Updated on: March 20,2024 12

High blood pressure's impact on white matter could be key to dementia prevention

by Heidi Douglass,University of New South WalesCredit: Pixabay/CC0 Public DomainA study from the Center for Healthy Brain Aging (CHeBA) provides compelling evidence for clinical practice to dire

Updated on:March 20,2024 12