New pathway in Alzheimer's disease provides earlier target for potential therapies

by Case Western Reserve UniversityCredit: CC0 Public DomainResearchers at the Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer's dis

Updated on: April 07,2024 16

New pathway in Alzheimer's disease provides earlier target for potential therapies

by Case Western Reserve UniversityCredit: CC0 Public DomainResearchers at the Case Western Reserve University School of Medicine have identified a new target in development of Alzheimer's dis

Updated on:April 07,2024 16

Alzheimer's risk gene disrupts endocytosis, but another disease-linked gene could help

by Massachusetts Institute of TechnologyAPOE4 Astrocytes showed an increase in endocytosis after overexpression of PICALM. In the bottom row, astrocytes (labeled blue), have taken up more of a pr

Updated on: April 07,2024 18

Alzheimer's risk gene disrupts endocytosis, but another disease-linked gene could help

by Massachusetts Institute of TechnologyAPOE4 Astrocytes showed an increase in endocytosis after overexpression of PICALM. In the bottom row, astrocytes (labeled blue), have taken up more of a pr

Updated on:April 07,2024 18

New study finds cell donor's socioeconomic status shapes cancer treatment outcomes

by Alex Smith,University of Minnesota Medical SchoolCredit: Pixabay/CC0 Public DomainA research team led by the University of Minnesota Medical School demonstrated that the socioeconomic status

Updated on: August 01,2024 0

New study finds cell donor's socioeconomic status shapes cancer treatment outcomes

by Alex Smith,University of Minnesota Medical SchoolCredit: Pixabay/CC0 Public DomainA research team led by the University of Minnesota Medical School demonstrated that the socioeconomic status

Updated on:August 01,2024 0

Multiple sclerosis drug may help with poor working memory

byUniversity of BaselPost-hoc analysis of the drug effect on the primary outcome per cognitive baseline group, violin plots. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-02

Updated on: November 24,2024 0

Multiple sclerosis drug may help with poor working memory

byUniversity of BaselPost-hoc analysis of the drug effect on the primary outcome per cognitive baseline group, violin plots. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-02

Updated on:November 24,2024 0

The link between headache disorders and suicide—a 25-year Danish cohort study

by Justin Jackson , Medical XpressCredit: Kindel Media from PexelsNew evidence from a large population-based cohort analysis indicates an increased risk of both attempted and completed suicide among i

Updated on: February 23,2025 0

The link between headache disorders and suicide—a 25-year Danish cohort study

by Justin Jackson , Medical XpressCredit: Kindel Media from PexelsNew evidence from a large population-based cohort analysis indicates an increased risk of both attempted and completed suicide among i

Updated on:February 23,2025 0

A potential new treatment target for Alzheimer's disease

by Keck School of Medicine of USCActivation of cyclophilin A (CypA; red upper panels) leads to activation of MMP9 (red lower panels) in CD13+-pericytes (green) in brain capillaries of APOE4 human

Updated on: April 07,2024 19

A potential new treatment target for Alzheimer's disease

by Keck School of Medicine of USCActivation of cyclophilin A (CypA; red upper panels) leads to activation of MMP9 (red lower panels) in CD13+-pericytes (green) in brain capillaries of APOE4 human

Updated on:April 07,2024 19

Promising pathways to simplified Alzheimer's diagnosis unveiled in new study

FEBRUARY 28, 2024by Global Alzheimer's Platform FoundationROC curves for prediction of brain PET or CSF amyloid positivity adjusted for age and apoE ε4 status with imputed values. Credit:Alz

Updated on: March 28,2024 3

Promising pathways to simplified Alzheimer's diagnosis unveiled in new study

FEBRUARY 28, 2024by Global Alzheimer's Platform FoundationROC curves for prediction of brain PET or CSF amyloid positivity adjusted for age and apoE ε4 status with imputed values. Credit:Alz

Updated on:March 28,2024 3

DNA molecules with 'invisibility cloak' sequences can selectively target diseased cells in motor neuron disease

byThe Francis Crick InstituteMouse neuron grown on coverslips. The dots of colour are individual synapses. Credit: The Francis Crick InstituteResearchers at the Francis Crick Institute and the U

Updated on: October 14,2024 0

DNA molecules with 'invisibility cloak' sequences can selectively target diseased cells in motor neuron disease

byThe Francis Crick InstituteMouse neuron grown on coverslips. The dots of colour are individual synapses. Credit: The Francis Crick InstituteResearchers at the Francis Crick Institute and the U

Updated on:October 14,2024 0

New insights into Niemann-Pick type C: A form of childhood dementia

by Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Bone marrow-derived macrophages (BMDMs) share key molecular and functional alterations observed in NPC1-deficient microglia. Credit:&

Updated on: December 17,2024 0

New insights into Niemann-Pick type C: A form of childhood dementia

by Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Bone marrow-derived macrophages (BMDMs) share key molecular and functional alterations observed in NPC1-deficient microglia. Credit:&

Updated on:December 17,2024 0

New research shows that the heart has a mini-brain—its own nervous system that controls the heartbeat

byKarolinska InstitutetNeuroanatomy of the adult zebrafish intracardiac nervous system. Neuroanatomy of the adult zebrafish intracardiac nervous system. Credit:Nature Communications(

Updated on: December 18,2024 0

New research shows that the heart has a mini-brain—its own nervous system that controls the heartbeat

byKarolinska InstitutetNeuroanatomy of the adult zebrafish intracardiac nervous system. Neuroanatomy of the adult zebrafish intracardiac nervous system. Credit:Nature Communications(

Updated on:December 18,2024 0

How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice

by Massachusetts Institute of TechnologyBright staining highlights VIP-expressing interneurons in this coronal cross-section of a mouse brain. The neurons may help drive glymphatic clearance of a

Updated on: March 08,2024 20

How 40Hz sensory gamma rhythm stimulation clears amyloid in Alzheimer's mice

by Massachusetts Institute of TechnologyBright staining highlights VIP-expressing interneurons in this coronal cross-section of a mouse brain. The neurons may help drive glymphatic clearance of a

Updated on:March 08,2024 20

Rate of Alzheimer's deaths on the rise

by Pennsylvania State UniversityCredit: Thinkstock/monkeybusinessimagesThe rate of death from Alzheimer's disease in the United States increased by more than 50 percent in the past 15 years,

Updated on: April 07,2024 13

Rate of Alzheimer's deaths on the rise

by Pennsylvania State UniversityCredit: Thinkstock/monkeybusinessimagesThe rate of death from Alzheimer's disease in the United States increased by more than 50 percent in the past 15 years,

Updated on:April 07,2024 13