An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Research highlights misdiagnosis for people with Alzheimer's disease

by Alzheimer's Research UKResearch presented today (Tuesday 26 July) at the Alzheimer's Association International Conference 2016 suggests that men with Alzheimer's may be more likely

Updated on: March 07,2024

Research highlights misdiagnosis for people with Alzheimer's disease

by Alzheimer's Research UKResearch presented today (Tuesday 26 July) at the Alzheimer's Association International Conference 2016 suggests that men with Alzheimer's may be more likely

Updated on:March 07,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on: May 18,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on:May 18,2024

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on: April 28,2025

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on:April 28,2025

Self-management group rehab benefits persons with dementia

(HealthDay)—Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in theJournal of the American Geri

Updated on: February 28,2024

Self-management group rehab benefits persons with dementia

(HealthDay)—Self-management group rehabilitation is beneficial for persons with dementia (PwD) and their spouses, according to a study published online April 5 in theJournal of the American Geri

Updated on:February 28,2024

People with dementia fail to get specialist care despite great need

by University College LondonCredit: University College LondonPeople suffering in the late stages of dementia receive most of their healthcare from GPs or emergency services rather than from speci

Updated on: May 08,2024

People with dementia fail to get specialist care despite great need

by University College LondonCredit: University College LondonPeople suffering in the late stages of dementia receive most of their healthcare from GPs or emergency services rather than from speci

Updated on:May 08,2024

How different areas of the prefrontal cortex influence time variability in individual monkeys

byRIKENDissociations in the involvement of six cortical regions in intra-individual RT variability. Credit:Nature Communications(2024). DOI: 10.1038/s41467-023-44341-5Neuroscientists

Updated on: July 31,2024

How different areas of the prefrontal cortex influence time variability in individual monkeys

byRIKENDissociations in the involvement of six cortical regions in intra-individual RT variability. Credit:Nature Communications(2024). DOI: 10.1038/s41467-023-44341-5Neuroscientists

Updated on:July 31,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on: September 06,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on:September 06,2024

Alzheimer's disease diagnostics could become more accessible

by National University of Science and Technology MISISNational University of Science and Technology MISISA team of researchers from the Laboratory of Biophysics at NUST MISIS, Lomonosov Moscow State U

Updated on: April 08,2024

Alzheimer's disease diagnostics could become more accessible

by National University of Science and Technology MISISNational University of Science and Technology MISISA team of researchers from the Laboratory of Biophysics at NUST MISIS, Lomonosov Moscow State U

Updated on:April 08,2024