Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on: February 28,2024 15

Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on:February 28,2024 15

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024 20

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024 20

PET scans reveal key details of Alzheimer's protein growth in aging brains

by University of California - BerkeleyShown are PET scans that track tau (top row) and beta-amyloid from two normal older people and a patient with Alzheimer's disease (AD). The normal older

Updated on: February 28,2024 16

PET scans reveal key details of Alzheimer's protein growth in aging brains

by University of California - BerkeleyShown are PET scans that track tau (top row) and beta-amyloid from two normal older people and a patient with Alzheimer's disease (AD). The normal older

Updated on:February 28,2024 16

Inflammation in the brain linked to several forms of dementia

by University of CambridgeCredit: CC0 Public DomainInflammation in the brain may be more widely implicated in dementias than was previously thought, suggests new research from the University of C

Updated on: May 18,2024 6

Inflammation in the brain linked to several forms of dementia

by University of CambridgeCredit: CC0 Public DomainInflammation in the brain may be more widely implicated in dementias than was previously thought, suggests new research from the University of C

Updated on:May 18,2024 6

Imaging technique shows Alzheimer's disease progress

by Wiebe Van Der Veen,University of TwenteThe high-lighted squares (left) are the 30 by 30 micron areas in the middle and right images (upper: plaque, lower: tangle). Credit: Univers

Updated on: May 06,2024 14

Imaging technique shows Alzheimer's disease progress

by Wiebe Van Der Veen,University of TwenteThe high-lighted squares (left) are the 30 by 30 micron areas in the middle and right images (upper: plaque, lower: tangle). Credit: Univers

Updated on:May 06,2024 14

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on: June 20,2024 4

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on:June 20,2024 4

LSL60101 compound reduces neuroinflammation and improves cognition

by University of BarcelonaCredit: Pixabay/CC0 Public DomainThe LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies a

Updated on: March 30,2024 15

LSL60101 compound reduces neuroinflammation and improves cognition

by University of BarcelonaCredit: Pixabay/CC0 Public DomainThe LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies a

Updated on:March 30,2024 15

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024 20

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024 20

Gut protein may protect brain cells in Parkinson's disease

by Moriah Cunningham,Thomas Jefferson UniversityFunctional GUCY2C protein and mRNA are expressed by DA neurons within the SNpc.aSchematic of mice used for analyses.b–dImm

Updated on: July 31,2024 0

Gut protein may protect brain cells in Parkinson's disease

by Moriah Cunningham,Thomas Jefferson UniversityFunctional GUCY2C protein and mRNA are expressed by DA neurons within the SNpc.aSchematic of mice used for analyses.b–dImm

Updated on:July 31,2024 0

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on: September 06,2024 0

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on:September 06,2024 0

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on: March 09,2024 20

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on:March 09,2024 20

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on: June 24,2024 8

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on:June 24,2024 8