Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024

Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on: February 28,2024

Study reveals the possibility of curbing synapse loss in Alzheimer's

by Children's Hospital BostonThis schematic shows how beta-amyloid (Aß) oligomers, the classical complement cascade and microglia work together to induce synapse loss in the pre-plaque Alzhei

Updated on:February 28,2024

Navigation skill test could diagnose Alzheimer's long before memory fails

by Gerry Everding,Washington University School of Medicine in St. LouisThe hippocampus (shown in red) is associated with cognitive mapping skills. Credit: Life Science Databases via Wikimedia Co

Updated on: February 28,2024

Navigation skill test could diagnose Alzheimer's long before memory fails

by Gerry Everding,Washington University School of Medicine in St. LouisThe hippocampus (shown in red) is associated with cognitive mapping skills. Credit: Life Science Databases via Wikimedia Co

Updated on:February 28,2024

Direct oral anticoagulants reduce dementia risk in Asian AFib patients compared to traditional blood thinners: Study

by American College of CardiologyCredit: Pixabay/CC0 Public DomainThe use of direct oral anticoagulants (DOACs) was associated with a reduction in dementia risk compared to traditional blood thin

Updated on: March 02,2024

Direct oral anticoagulants reduce dementia risk in Asian AFib patients compared to traditional blood thinners: Study

by American College of CardiologyCredit: Pixabay/CC0 Public DomainThe use of direct oral anticoagulants (DOACs) was associated with a reduction in dementia risk compared to traditional blood thin

Updated on:March 02,2024

New study reveals how biological sex influences brain proteins and disease risk

by Emory UniversitySummary of main analyses. Credit:Nature Medicine(2023). DOI:10.1038/s41591-023-02509-yAn Emory led study published inNature MedicineandSynapse&nbs

Updated on: March 02,2024

New study reveals how biological sex influences brain proteins and disease risk

by Emory UniversitySummary of main analyses. Credit:Nature Medicine(2023). DOI:10.1038/s41591-023-02509-yAn Emory led study published inNature MedicineandSynapse&nbs

Updated on:March 02,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on: September 06,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on:September 06,2024

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on: March 09,2024

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on:March 09,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on: March 28,2024

Mitochondrial DNA fragment losses predict Parkinson's disease before symptoms appear

byUniversity of BarcelonaImage of a fibroblast from a patient with Parkinson's disease. Mitochondria are shown in green and fragments of damaged mitochondria in red. Some of these fragments

Updated on:March 28,2024

PET scans reveal key details of Alzheimer's protein growth in aging brains

by University of California - BerkeleyShown are PET scans that track tau (top row) and beta-amyloid from two normal older people and a patient with Alzheimer's disease (AD). The normal older

Updated on: February 28,2024

PET scans reveal key details of Alzheimer's protein growth in aging brains

by University of California - BerkeleyShown are PET scans that track tau (top row) and beta-amyloid from two normal older people and a patient with Alzheimer's disease (AD). The normal older

Updated on:February 28,2024

Researchers develop combined data model to better evaluate for mild cognitive impairment

by Boston University School of MedicineA new study has shown that by combining imaging and neuropsychological testing, one can more accurately assess the cognitive status of individuals.Cognitive

Updated on: March 07,2024

Researchers develop combined data model to better evaluate for mild cognitive impairment

by Boston University School of MedicineA new study has shown that by combining imaging and neuropsychological testing, one can more accurately assess the cognitive status of individuals.Cognitive

Updated on:March 07,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on: September 06,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on:September 06,2024