Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on: May 18,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on:May 18,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on: February 05,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on:February 05,2024

People with dementia fail to get specialist care despite great need

by University College LondonCredit: University College LondonPeople suffering in the late stages of dementia receive most of their healthcare from GPs or emergency services rather than from speci

Updated on: May 08,2024

People with dementia fail to get specialist care despite great need

by University College LondonCredit: University College LondonPeople suffering in the late stages of dementia receive most of their healthcare from GPs or emergency services rather than from speci

Updated on:May 08,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on: July 31,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on:July 31,2024

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on: June 24,2024

Tips for reducing dementia risk

by Susan Barber LindquistCredit: Pixabay/CC0 Public DomainMore than 55 million people worldwide are believed to be living with dementia, according to the World Health Organization. Ronald Petersen, M.

Updated on:June 24,2024

Alzheimer's disease diagnostics could become more accessible

by National University of Science and Technology MISISNational University of Science and Technology MISISA team of researchers from the Laboratory of Biophysics at NUST MISIS, Lomonosov Moscow State U

Updated on: April 08,2024

Alzheimer's disease diagnostics could become more accessible

by National University of Science and Technology MISISNational University of Science and Technology MISISA team of researchers from the Laboratory of Biophysics at NUST MISIS, Lomonosov Moscow State U

Updated on:April 08,2024

An implant to prevent Alzheimer's

by Ecole Polytechnique Federale de LausanneAn infographic of how the implanted capsule releases antibodies to the brain. Credit: Patrick Aebischer (EPFL)In a cutting-edge treatment for Alzheimer&

Updated on: February 28,2024

An implant to prevent Alzheimer's

by Ecole Polytechnique Federale de LausanneAn infographic of how the implanted capsule releases antibodies to the brain. Credit: Patrick Aebischer (EPFL)In a cutting-edge treatment for Alzheimer&

Updated on:February 28,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on: June 20,2024

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on:June 20,2024