LSL60101 compound reduces neuroinflammation and improves cognition

by University of BarcelonaCredit: Pixabay/CC0 Public DomainThe LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies a

Updated on: March 30,2024 15

LSL60101 compound reduces neuroinflammation and improves cognition

by University of BarcelonaCredit: Pixabay/CC0 Public DomainThe LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies a

Updated on:March 30,2024 15

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024 20

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024 20

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on: February 26,2024 13

Extending use of existing Alzheimer's drug could delay move into nursing home

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Newly-released follow-up analysis from a 2012 clinical trial led by a

Updated on:February 26,2024 13

Decoding the hidden signals of aggression and arousal in the brain

byCalifornia Institute of TechnologyAttractor dynamics in head-fixed mice observing aggression. Credit:Nature(2024). DOI: 10.1038/s41586-024-07915-xA series of three papers from neur

Updated on: November 07,2024 0

Decoding the hidden signals of aggression and arousal in the brain

byCalifornia Institute of TechnologyAttractor dynamics in head-fixed mice observing aggression. Credit:Nature(2024). DOI: 10.1038/s41586-024-07915-xA series of three papers from neur

Updated on:November 07,2024 0

PET scans reveal key details of Alzheimer's protein growth in aging brains

by University of California - BerkeleyShown are PET scans that track tau (top row) and beta-amyloid from two normal older people and a patient with Alzheimer's disease (AD). The normal older

Updated on: February 28,2024 16

PET scans reveal key details of Alzheimer's protein growth in aging brains

by University of California - BerkeleyShown are PET scans that track tau (top row) and beta-amyloid from two normal older people and a patient with Alzheimer's disease (AD). The normal older

Updated on:February 28,2024 16

Taking proton pump inhibitors not linked to higher dementia risk

by American Geriatrics SocietyProton pump inhibitors (PPIs) are medicines commonly prescribed to treat acid-related digestive problems, including gastroesophageal reflux disease (or GERD). As of

Updated on: March 07,2024 19

Taking proton pump inhibitors not linked to higher dementia risk

by American Geriatrics SocietyProton pump inhibitors (PPIs) are medicines commonly prescribed to treat acid-related digestive problems, including gastroesophageal reflux disease (or GERD). As of

Updated on:March 07,2024 19

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on: March 09,2024 11

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on:March 09,2024 11

Can a calculator predict your risk of dementia?

by The Ottawa HospitalResearchers have built and validated an online calculator that empowers individuals 55 and over to better understand the health of their brain and how they can reduce their risk

Updated on: June 18,2024 5

Can a calculator predict your risk of dementia?

by The Ottawa HospitalResearchers have built and validated an online calculator that empowers individuals 55 and over to better understand the health of their brain and how they can reduce their risk

Updated on:June 18,2024 5

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024 0

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024 0

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on: June 20,2024 4

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on:June 20,2024 4

Living with the risk of Alzheimer's disease

by University of CologneWhat are the expectations of persons who decide to have their risk of Alzheimer's Disease tested? What should doctors pay attention to when ascertaining individual ris

Updated on: March 07,2024 12

Living with the risk of Alzheimer's disease

by University of CologneWhat are the expectations of persons who decide to have their risk of Alzheimer's Disease tested? What should doctors pay attention to when ascertaining individual ris

Updated on:March 07,2024 12

Could blood pressure drugs have a role in Alzheimer's disease treatment?

by Georgetown University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In laboratory neuronal cultures, an FDA-approved drug used to

Updated on: February 27,2024 19

Could blood pressure drugs have a role in Alzheimer's disease treatment?

by Georgetown University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In laboratory neuronal cultures, an FDA-approved drug used to

Updated on:February 27,2024 19