Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on: February 28,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on:February 28,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on: May 18,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on:May 18,2024

Inflammation in the brain linked to several forms of dementia

by University of CambridgeCredit: CC0 Public DomainInflammation in the brain may be more widely implicated in dementias than was previously thought, suggests new research from the University of C

Updated on: May 18,2024

Inflammation in the brain linked to several forms of dementia

by University of CambridgeCredit: CC0 Public DomainInflammation in the brain may be more widely implicated in dementias than was previously thought, suggests new research from the University of C

Updated on:May 18,2024

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on: March 02,2024

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on:March 02,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on: February 26,2024

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on:February 26,2024

Untangling tau—researchers find a 'druggable target' for treating Alzheimer's disease

by University of California - San DiegoA micrograph by Thomas Deerinck of the National Center for Microscopy and Imaging Research at UC San Diego School of Medicine depicts tangles of tau protein

Updated on: July 01,2024

Untangling tau—researchers find a 'druggable target' for treating Alzheimer's disease

by University of California - San DiegoA micrograph by Thomas Deerinck of the National Center for Microscopy and Imaging Research at UC San Diego School of Medicine depicts tangles of tau protein

Updated on:July 01,2024

Gut bacteria make pomegranate metabolites that may protect against Alzheimer's disease

by American Chemical SocietyIn a quest to stay healthy, many people are seeking natural ways to prevent neurodegenerative diseases. Recent studies show that pomegranate extract, which is a rich s

Updated on: February 27,2024

Gut bacteria make pomegranate metabolites that may protect against Alzheimer's disease

by American Chemical SocietyIn a quest to stay healthy, many people are seeking natural ways to prevent neurodegenerative diseases. Recent studies show that pomegranate extract, which is a rich s

Updated on:February 27,2024

Does glaucoma affect cognitive function?

by WileyAcute angle closure glaucoma of the right eye (intraocular pressure was 42 in the right eye). Credit: James Heilman, MD/WikipediaPrevious studies have looked for links between glaucoma—a

Updated on: March 09,2024

Does glaucoma affect cognitive function?

by WileyAcute angle closure glaucoma of the right eye (intraocular pressure was 42 in the right eye). Credit: James Heilman, MD/WikipediaPrevious studies have looked for links between glaucoma—a

Updated on:March 09,2024

The evolution of amyloid toxicity in Alzheimer's

by Biophysical SocietyThe suspected molecular dagger in Alzheimer's, shown here in red attacking cells (grey), contains a special twist. Credit: MaitiA tiny protein known as an "amyloid beta&

Updated on: February 28,2024

The evolution of amyloid toxicity in Alzheimer's

by Biophysical SocietyThe suspected molecular dagger in Alzheimer's, shown here in red attacking cells (grey), contains a special twist. Credit: MaitiA tiny protein known as an "amyloid beta&

Updated on:February 28,2024

Scientists discover a trigger of Alzheimer's disease

by Lomonosov Moscow State UniversityThree-dimensional structure of the dimer of the metal-binding domain of beta-amyloid peptide having 'English mutation'. Two peptide molecules connected

Updated on: February 28,2024

Scientists discover a trigger of Alzheimer's disease

by Lomonosov Moscow State UniversityThree-dimensional structure of the dimer of the metal-binding domain of beta-amyloid peptide having 'English mutation'. Two peptide molecules connected

Updated on:February 28,2024

Residence in disadvantaged neighborhoods increases dementia risk

by Elana GotkineFor older veterans, residence within more disadvantaged neighborhoods is associated with an increased risk for dementia, according to a study published online July 19 inJAMA Neur

Updated on: July 04,2024

Residence in disadvantaged neighborhoods increases dementia risk

by Elana GotkineFor older veterans, residence within more disadvantaged neighborhoods is associated with an increased risk for dementia, according to a study published online July 19 inJAMA Neur

Updated on:July 04,2024

AI decodes whole-cortex functional images to predict behavioral states

byKobe UniversityA new "end-to-end" deep learning method for the prediction of behavioral states uses whole-cortex functional imaging that do not require preprocessing or pre-specified

Updated on: March 28,2024

AI decodes whole-cortex functional images to predict behavioral states

byKobe UniversityA new "end-to-end" deep learning method for the prediction of behavioral states uses whole-cortex functional imaging that do not require preprocessing or pre-specified

Updated on:March 28,2024