Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on: April 20,2024

Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on:April 20,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on: March 09,2024

'Lesser of two evils' argument used to defend antipsychotic overuse for dementia

by University of ReadingCredit: University of ReadingThe increasing use of antipsychotic drugs to manage dementia in care homes has been explained by some practitioners as "the lesser of two

Updated on:March 09,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on: March 09,2024

How an Alzheimer's-related protein forms plaques

by Leiden UniversityCredit: Leiden UniversityNeurological diseases such as Alzheimer's disease are characterised by aggregates of protein in the brain. The connection of these aggregates to t

Updated on:March 09,2024

Blood-based multiplexed diagnostic sensor helps to accurately detect Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Figure: A schematic diagram of a high-density aligned carbon nanotube-based resistive sensor that distinguishes patients with Alzh

Updated on: June 18,2024

Blood-based multiplexed diagnostic sensor helps to accurately detect Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Figure: A schematic diagram of a high-density aligned carbon nanotube-based resistive sensor that distinguishes patients with Alzh

Updated on:June 18,2024

Cracking the code for cerebellar movement disorders

byTexas Children's HospitalSupervised classifier model predicts mouse phenotype based on spike signatures. Credit:eLife(2024). DOI: 10.7554/eLife.91483.2The cerebellum is a regio

Updated on: July 05,2024

Cracking the code for cerebellar movement disorders

byTexas Children's HospitalSupervised classifier model predicts mouse phenotype based on spike signatures. Credit:eLife(2024). DOI: 10.7554/eLife.91483.2The cerebellum is a regio

Updated on:July 05,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on: April 16,2024

Investigational Alzheimer's drug improves biomarkers of the disease

by Washington University School of MedicineRandall Bateman, MD, director of the Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU), an ongoing international clinical trial to evaluate e

Updated on:April 16,2024

Depression and dementia in the age of COVID-19

by Donald Weaver,The ConversationMore than half of patients with dementia also suffer from depression. If the depression remains untreated, the associated memory and cognitive problems worsen. C

Updated on: March 30,2024

Depression and dementia in the age of COVID-19

by Donald Weaver,The ConversationMore than half of patients with dementia also suffer from depression. If the depression remains untreated, the associated memory and cognitive problems worsen. C

Updated on:March 30,2024

Lost and found: Japan tags dementia sufferers with barcodes

A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.A company in Iruma, north

Updated on: March 07,2024

Lost and found: Japan tags dementia sufferers with barcodes

A Japanese city has introduced a novel way to keep track of senior citizens with dementia who are prone to getting lost—tagging their fingers and toes with scan-able barcodes.A company in Iruma, north

Updated on:March 07,2024

Receptor structure reveals novel drug design opportunities for Parkinson's disease

by Justin Jackson , Medical XpressTop and side views of GPR6 structures in different conformational states. Credit:Science Signaling(2024). DOI: 10.1126/scisignal.ado8741University of Sout

Updated on: December 17,2024

Receptor structure reveals novel drug design opportunities for Parkinson's disease

by Justin Jackson , Medical XpressTop and side views of GPR6 structures in different conformational states. Credit:Science Signaling(2024). DOI: 10.1126/scisignal.ado8741University of Sout

Updated on:December 17,2024

Detecting dementia in the blood

by Swiss Federal Laboratories for Materials Science and TechnologyEmpa researcher Peter Nirmalraj analyzes blood samples using atomic force microscopy (AFM). Credit: EmpaIf the suspicion of Alzhe

Updated on: March 30,2024

Detecting dementia in the blood

by Swiss Federal Laboratories for Materials Science and TechnologyEmpa researcher Peter Nirmalraj analyzes blood samples using atomic force microscopy (AFM). Credit: EmpaIf the suspicion of Alzhe

Updated on:March 30,2024

Using tau imaging as diagnostic marker for Alzheimer disease

by The JAMA Network JournalsThe accumulation of β-Amyloid (Αβ) and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tra

Updated on: March 07,2024

Using tau imaging as diagnostic marker for Alzheimer disease

by The JAMA Network JournalsThe accumulation of β-Amyloid (Αβ) and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tra

Updated on:March 07,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024