Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024

Hippocampus study shows chronic pain can be predicted within three days of whiplash injury

byNorthwestern UniversityHippocampal head, body, and tail seeds were defined from the hippocampal parcellation of ref, and target hippocampal network ROIs were defined using the Harvard–Oxford C

Updated on: November 06,2024

Hippocampus study shows chronic pain can be predicted within three days of whiplash injury

byNorthwestern UniversityHippocampal head, body, and tail seeds were defined from the hippocampal parcellation of ref, and target hippocampal network ROIs were defined using the Harvard–Oxford C

Updated on:November 06,2024

Higher antioxidant levels linked to lower dementia risk

by American Academy of NeurologyCredit: CC0 Public DomainPeople with higher levels of antioxidants in their blood may be less likely to develop dementia, according to a study published in the May

Updated on: June 24,2024

Higher antioxidant levels linked to lower dementia risk

by American Academy of NeurologyCredit: CC0 Public DomainPeople with higher levels of antioxidants in their blood may be less likely to develop dementia, according to a study published in the May

Updated on:June 24,2024

Progress on early detection of Alzheimer's disease

by Laurie Fickman,University of HoustonCredit: Pixabay/CC0 Public DomainInside the body, some seemingly harmless proteins have sinister potential. In the case of Alzheimer's disease, the amy

Updated on: April 16,2024

Progress on early detection of Alzheimer's disease

by Laurie Fickman,University of HoustonCredit: Pixabay/CC0 Public DomainInside the body, some seemingly harmless proteins have sinister potential. In the case of Alzheimer's disease, the amy

Updated on:April 16,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on: March 30,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on:March 30,2024

Minimally invasive neural interface allows brain access without skull opening

byRice UniversityEndocisternal neural interface in human and sheep models. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s41551-024-01281-9A team of researchers led by Ric

Updated on: November 28,2024

Minimally invasive neural interface allows brain access without skull opening

byRice UniversityEndocisternal neural interface in human and sheep models. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s41551-024-01281-9A team of researchers led by Ric

Updated on:November 28,2024

Curcumin for amyloidosis and lipid metabolism—a novel insight

by Shinshu UniversitySchematic diagram of the effect of curcumin mediated by PPARa pathway in AApoAII amyloidosis model mouse. Credit: Jian DaiCurcumin is a polyphenol compound produced by plants of t

Updated on: June 24,2024

Curcumin for amyloidosis and lipid metabolism—a novel insight

by Shinshu UniversitySchematic diagram of the effect of curcumin mediated by PPARa pathway in AApoAII amyloidosis model mouse. Credit: Jian DaiCurcumin is a polyphenol compound produced by plants of t

Updated on:June 24,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Neurons involved in cognitive flexibility communicate at a distance

by Marie Simon,Paris Brain InstituteNeuron projection. Credit: N. Gupta, National Institute of Child Health and Human Development, National Institutes of Health.To adapt to the small and large e

Updated on: February 05,2024

Neurons involved in cognitive flexibility communicate at a distance

by Marie Simon,Paris Brain InstituteNeuron projection. Credit: N. Gupta, National Institute of Child Health and Human Development, National Institutes of Health.To adapt to the small and large e

Updated on:February 05,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on: May 13,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on:May 13,2024

Parkinson's paradox: When more dopamine means more tremor

byChampalimaud Centre for the UnknownReduced dopamine loss is linked to tremor in Parkinson's patients, challenging common beliefs. Credit: Neural Circuits Dysfunction Lab, Champalimaud Foun

Updated on: November 27,2024

Parkinson's paradox: When more dopamine means more tremor

byChampalimaud Centre for the UnknownReduced dopamine loss is linked to tremor in Parkinson's patients, challenging common beliefs. Credit: Neural Circuits Dysfunction Lab, Champalimaud Foun

Updated on:November 27,2024