Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on: October 21,2024

Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on:October 21,2024

Brain iron accumulation linked to cognitive decline in Alzheimer's patients

by Radiological Society of North AmericaR2? maps of healthy control participants and participants with Alzheimer disease. R2? maps are windowed between 10 and 50 sec21. Differences in iron concen

Updated on: April 10,2024

Brain iron accumulation linked to cognitive decline in Alzheimer's patients

by Radiological Society of North AmericaR2? maps of healthy control participants and participants with Alzheimer disease. R2? maps are windowed between 10 and 50 sec21. Differences in iron concen

Updated on:April 10,2024

Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on: August 08,2024

Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on:August 08,2024

Uncovering the unusual way aggregates hijack proteins

by Utrecht University,Utrecht University Faculty of ScienceTau stacking. Credit: Stefan Rudiger - Utrecht UniversityUtrecht scientists have uncovered how aggregates alter the behavior of Tau pro

Updated on: July 01,2024

Uncovering the unusual way aggregates hijack proteins

by Utrecht University,Utrecht University Faculty of ScienceTau stacking. Credit: Stefan Rudiger - Utrecht UniversityUtrecht scientists have uncovered how aggregates alter the behavior of Tau pro

Updated on:July 01,2024

Study shows beneficial effects of blocking brain inflammation in experimental model of Alzheimer's

by University of SouthamptonDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A University of Southampton-led study has found that blocking a receptor

Updated on: February 27,2024

Study shows beneficial effects of blocking brain inflammation in experimental model of Alzheimer's

by University of SouthamptonDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A University of Southampton-led study has found that blocking a receptor

Updated on:February 27,2024

Dementia diagnosis linked to unnecessary medication use

by University of SydneyCredit: CC0 Public DomainA new international study led by University of Sydney has found that medication use increases in newly diagnosed dementia patients, particularly un

Updated on: May 11,2024

Dementia diagnosis linked to unnecessary medication use

by University of SydneyCredit: CC0 Public DomainA new international study led by University of Sydney has found that medication use increases in newly diagnosed dementia patients, particularly un

Updated on:May 11,2024

LSL60101 compound reduces neuroinflammation and improves cognition

by University of BarcelonaCredit: Pixabay/CC0 Public DomainThe LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies a

Updated on: March 30,2024

LSL60101 compound reduces neuroinflammation and improves cognition

by University of BarcelonaCredit: Pixabay/CC0 Public DomainThe LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies a

Updated on:March 30,2024

Taking proton pump inhibitors not linked to higher dementia risk

by American Geriatrics SocietyProton pump inhibitors (PPIs) are medicines commonly prescribed to treat acid-related digestive problems, including gastroesophageal reflux disease (or GERD). As of

Updated on: March 07,2024

Taking proton pump inhibitors not linked to higher dementia risk

by American Geriatrics SocietyProton pump inhibitors (PPIs) are medicines commonly prescribed to treat acid-related digestive problems, including gastroesophageal reflux disease (or GERD). As of

Updated on:March 07,2024

HIV drug shown to help protect against build-up of dementia-related proteins in mouse brains

by University of CambridgeGraphical Abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.04.006Cambridge scientists have shown how the brain's ability to clear out toxic prot

Updated on: March 30,2024

HIV drug shown to help protect against build-up of dementia-related proteins in mouse brains

by University of CambridgeGraphical Abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.04.006Cambridge scientists have shown how the brain's ability to clear out toxic prot

Updated on:March 30,2024

Physicians debate best screening tools and practices for patients with potential dementia and cognitive impairment

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainIn a new Annals 'Beyond the Guideline's feature, two experts review the available evidence about cognitive impairment to

Updated on: March 02,2024

Physicians debate best screening tools and practices for patients with potential dementia and cognitive impairment

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainIn a new Annals 'Beyond the Guideline's feature, two experts review the available evidence about cognitive impairment to

Updated on:March 02,2024

Progress on early detection of Alzheimer's disease

by Laurie Fickman,University of HoustonCredit: Pixabay/CC0 Public DomainInside the body, some seemingly harmless proteins have sinister potential. In the case of Alzheimer's disease, the amy

Updated on: April 16,2024

Progress on early detection of Alzheimer's disease

by Laurie Fickman,University of HoustonCredit: Pixabay/CC0 Public DomainInside the body, some seemingly harmless proteins have sinister potential. In the case of Alzheimer's disease, the amy

Updated on:April 16,2024

Different 'subtypes' of Alzheimer's may be linked to different modifications of the tau protein

by Massachusetts General HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study reveals a possible biological reason that Alzheimer&#39

Updated on: April 07,2024

Different 'subtypes' of Alzheimer's may be linked to different modifications of the tau protein

by Massachusetts General HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study reveals a possible biological reason that Alzheimer&#39

Updated on:April 07,2024