Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on: June 18,2024 7

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on:June 18,2024 7

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024 0

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024 0

Earlier menopause plus high cardiovascular risk may lead to cognitive problems later

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainEarlier menopause combined with higher risk of cardiovascular disease is linked to an increased risk of thinking and memory proble

Updated on: April 06,2024 0

Earlier menopause plus high cardiovascular risk may lead to cognitive problems later

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainEarlier menopause combined with higher risk of cardiovascular disease is linked to an increased risk of thinking and memory proble

Updated on:April 06,2024 0

Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on: May 18,2024 4

Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on:May 18,2024 4

LipiDiDiet finds broadly sustainable effects of nutrient intervention in early Alzheimer's

by Saarland UniversityCredit: CC0 Public DomainTrial participants who received a multinutrient formulation over an extended period of time showed a significantly less rapid deterioration in cogni

Updated on: March 30,2024 16

LipiDiDiet finds broadly sustainable effects of nutrient intervention in early Alzheimer's

by Saarland UniversityCredit: CC0 Public DomainTrial participants who received a multinutrient formulation over an extended period of time showed a significantly less rapid deterioration in cogni

Updated on:March 30,2024 16

Detecting Alzheimer's disease in the blood

by Hokkaido UniversityConcept for digital detection of amyloid β-binding exosomes in the blood of an Alzheimer's disease model mouse. Credit: Kohei YuyamaResearchers from Hokkaido University

Updated on: June 20,2024 6

Detecting Alzheimer's disease in the blood

by Hokkaido UniversityConcept for digital detection of amyloid β-binding exosomes in the blood of an Alzheimer's disease model mouse. Credit: Kohei YuyamaResearchers from Hokkaido University

Updated on:June 20,2024 6

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on: March 09,2024 12

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on:March 09,2024 12

Signals from muscle protect from dementia

by St. Jude Children's Research HospitalResearch in the lab of Fabio Demontis, PhD, of Developmental Neurobiology, used immunostaining and confocal microscopy on fruit fly brain and retina ce

Updated on: June 14,2024 6

Signals from muscle protect from dementia

by St. Jude Children's Research HospitalResearch in the lab of Fabio Demontis, PhD, of Developmental Neurobiology, used immunostaining and confocal microscopy on fruit fly brain and retina ce

Updated on:June 14,2024 6

Children's headaches and mental health worsened during pandemic

by Children's National HospitalCredit: Unsplash/CC0 Public DomainSince the beginning of the COVID-19 pandemic, many pediatric patients who suffer from headaches have experienced more frequent

Updated on: February 18,2024 15

Children's headaches and mental health worsened during pandemic

by Children's National HospitalCredit: Unsplash/CC0 Public DomainSince the beginning of the COVID-19 pandemic, many pediatric patients who suffer from headaches have experienced more frequent

Updated on:February 18,2024 15

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on: April 02,2024 16

Tau does not stabilize microtubules, challenges approach to treating Alzheimer's

by Drexel UniversityThis image represents the role of tau and MAP6 in regulating the stable (green) and dynamic (red) parts of a neuron's microtubules. Depleting tau from cultured rat neurons

Updated on:April 02,2024 16

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on: May 21,2024 8

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on:May 21,2024 8

People living with dementia add voice to care model debate

by Flinders UniversityCredit: CC0 Public DomainCoinciding with Dementia Awareness Month, a new Flinders University study has asked Australian aged-care residents to rate the quality of care they

Updated on: May 08,2024 5

People living with dementia add voice to care model debate

by Flinders UniversityCredit: CC0 Public DomainCoinciding with Dementia Awareness Month, a new Flinders University study has asked Australian aged-care residents to rate the quality of care they

Updated on:May 08,2024 5