New synapse type discovered through spatial proteomics

by Tamara Bäßler,Max Planck SocietyNeuronal atlas with 30 different protein types in spatial resolution, visualized with the new SUM-PAINT method. The detailed images illustrate the extremely hi

Updated on: March 30,2024

New synapse type discovered through spatial proteomics

by Tamara Bäßler,Max Planck SocietyNeuronal atlas with 30 different protein types in spatial resolution, visualized with the new SUM-PAINT method. The detailed images illustrate the extremely hi

Updated on:March 30,2024

Salt-seeking behavior traced to specific brain neurons

byUniversity of IowaCredit: Pixabay/CC0 Public DomainSalt, or more precisely the sodium it contains, is very much a "Goldilocks" nutrient. Low sodium levels cause a drop in blood volum

Updated on: January 19,2025

Salt-seeking behavior traced to specific brain neurons

byUniversity of IowaCredit: Pixabay/CC0 Public DomainSalt, or more precisely the sodium it contains, is very much a "Goldilocks" nutrient. Low sodium levels cause a drop in blood volum

Updated on:January 19,2025

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on: March 02,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on:March 02,2024

Residence in disadvantaged neighborhoods increases dementia risk

by Elana GotkineFor older veterans, residence within more disadvantaged neighborhoods is associated with an increased risk for dementia, according to a study published online July 19 inJAMA Neur

Updated on: July 04,2024

Residence in disadvantaged neighborhoods increases dementia risk

by Elana GotkineFor older veterans, residence within more disadvantaged neighborhoods is associated with an increased risk for dementia, according to a study published online July 19 inJAMA Neur

Updated on:July 04,2024

An Alzheimer's treatment would tax the US health care system

by RAND CorporationThe flow of how an Alzheimer's treatment would get to patients after approval. Credit: RAND Corp.The U.S. health care system lacks the capacity to rapidly move a treatment

Updated on: April 08,2024

An Alzheimer's treatment would tax the US health care system

by RAND CorporationThe flow of how an Alzheimer's treatment would get to patients after approval. Credit: RAND Corp.The U.S. health care system lacks the capacity to rapidly move a treatment

Updated on:April 08,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Forecasting method may help people with epilepsy predict their seizures

byUniversity of California, San FranciscoMapping network connectivity to cycles of seizure likelihood. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03149-6A team of epilepsy

Updated on: July 31,2024

Forecasting method may help people with epilepsy predict their seizures

byUniversity of California, San FranciscoMapping network connectivity to cycles of seizure likelihood. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03149-6A team of epilepsy

Updated on:July 31,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on: July 17,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on:July 17,2024

Excess body fat tied to lower cognitive scores in adults

(HealthDay)—Both generalized and visceral adiposity are associated with lower cognitive scores throughout midlife, according to a study published online Feb. 1 inJAMA Network Open.Sonia S. Anand

Updated on: February 05,2024

Excess body fat tied to lower cognitive scores in adults

(HealthDay)—Both generalized and visceral adiposity are associated with lower cognitive scores throughout midlife, according to a study published online Feb. 1 inJAMA Network Open.Sonia S. Anand

Updated on:February 05,2024

Potential noninvasive test for Alzheimer's disease

by University of Central LancashireProfessor Francis Martin, principal investigator of the study and Biosciences theme lead at UCLan. Credit: University of Central LancashireIn the largest and most co

Updated on: April 07,2024

Potential noninvasive test for Alzheimer's disease

by University of Central LancashireProfessor Francis Martin, principal investigator of the study and Biosciences theme lead at UCLan. Credit: University of Central LancashireIn the largest and most co

Updated on:April 07,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on: March 07,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on:March 07,2024