Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on: October 21,2024

Key mechanisms in asymptomatic Alzheimer's disease brains offer potential protection against cognitive decline

byIndiana UniversityMicroglia and astrocytic coverage around compact, intermediate, and filamentous amyloid plaques between AD and AsymAD cases. Credit:Acta Neuropathologica(2024). D

Updated on:October 21,2024

Colonic diverticular disease linked to dementia risk

(HealthDay)—Colonic diverticular disease appears to be associated with increased risk of dementia in a population from Taiwan, according to a study published online March 31 in theJournal of Gas

Updated on: February 28,2024

Colonic diverticular disease linked to dementia risk

(HealthDay)—Colonic diverticular disease appears to be associated with increased risk of dementia in a population from Taiwan, according to a study published online March 31 in theJournal of Gas

Updated on:February 28,2024

Scientists discover 'entirely unanticipated' role of protein netrin1 in spinal cord development

by Ani Vahradyan,University of California, Los AngelesCells (blue) at the ventral midline of the spinal cord, expressing netrin1 (red) and a fluorescent tracer (GFP, green). Credit: Samantha But

Updated on: November 22,2024

Scientists discover 'entirely unanticipated' role of protein netrin1 in spinal cord development

by Ani Vahradyan,University of California, Los AngelesCells (blue) at the ventral midline of the spinal cord, expressing netrin1 (red) and a fluorescent tracer (GFP, green). Credit: Samantha But

Updated on:November 22,2024

Older Americans' finances decline in years before dementia diagnosis

by Ernie MundellPerhaps succumbing to fraudsters or facing mounting bills, older Americans begin losing wealth in the years preceding a definitive dementia diagnosis, new research shows.For example, t

Updated on: March 02,2024

Older Americans' finances decline in years before dementia diagnosis

by Ernie MundellPerhaps succumbing to fraudsters or facing mounting bills, older Americans begin losing wealth in the years preceding a definitive dementia diagnosis, new research shows.For example, t

Updated on:March 02,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on: April 20,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on:April 20,2024

Receptor structure reveals novel drug design opportunities for Parkinson's disease

by Justin Jackson , Medical XpressTop and side views of GPR6 structures in different conformational states. Credit:Science Signaling(2024). DOI: 10.1126/scisignal.ado8741University of Sout

Updated on: December 17,2024

Receptor structure reveals novel drug design opportunities for Parkinson's disease

by Justin Jackson , Medical XpressTop and side views of GPR6 structures in different conformational states. Credit:Science Signaling(2024). DOI: 10.1126/scisignal.ado8741University of Sout

Updated on:December 17,2024

Caregiver burden in dementia during the COVID-19 crisis

by IOS PressCredit: CC0 Public DomainCaregivers of people with dementia and milder forms of neurocognitive disorder bear a heavy burden. They are constantly confronted with challenging symptoms a

Updated on: March 30,2024

Caregiver burden in dementia during the COVID-19 crisis

by IOS PressCredit: CC0 Public DomainCaregivers of people with dementia and milder forms of neurocognitive disorder bear a heavy burden. They are constantly confronted with challenging symptoms a

Updated on:March 30,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on: March 30,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on:March 30,2024

Excess body fat tied to lower cognitive scores in adults

(HealthDay)—Both generalized and visceral adiposity are associated with lower cognitive scores throughout midlife, according to a study published online Feb. 1 inJAMA Network Open.Sonia S. Anand

Updated on: February 05,2024

Excess body fat tied to lower cognitive scores in adults

(HealthDay)—Both generalized and visceral adiposity are associated with lower cognitive scores throughout midlife, according to a study published online Feb. 1 inJAMA Network Open.Sonia S. Anand

Updated on:February 05,2024

Alzheimer's disease consists of three distinct subtypes, according to study

by Kim Irwin,University of California, Los AngelesDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Alzheimer's disease, long thought to be a sin

Updated on: February 26,2024

Alzheimer's disease consists of three distinct subtypes, according to study

by Kim Irwin,University of California, Los AngelesDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Alzheimer's disease, long thought to be a sin

Updated on:February 26,2024

Alzheimer's disease and type 2 diabetes: Synthetic peptides may suppress formation of harmful amyloid aggregates

by Technical University MunichProposed mechanism and hypothetical models of IAPP/ACM nanofiber co-assembly versus IAPP amyloid self-assembly. The lower part, IAPP self-assembly into toxic oligome

Updated on: April 08,2024

Alzheimer's disease and type 2 diabetes: Synthetic peptides may suppress formation of harmful amyloid aggregates

by Technical University MunichProposed mechanism and hypothetical models of IAPP/ACM nanofiber co-assembly versus IAPP amyloid self-assembly. The lower part, IAPP self-assembly into toxic oligome

Updated on:April 08,2024

Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds

by Sarah L. Spaulding,Yale UniversitySystemic sclerosis study participants before and after treatment with hyaluronic acid filler. Credit:JAAD Case Reports(2024). DOI: 10.1016/j.jdcr

Updated on: August 01,2024

Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds

by Sarah L. Spaulding,Yale UniversitySystemic sclerosis study participants before and after treatment with hyaluronic acid filler. Credit:JAAD Case Reports(2024). DOI: 10.1016/j.jdcr

Updated on:August 01,2024