Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

Alzheimer's disease and type 2 diabetes: Synthetic peptides may suppress formation of harmful amyloid aggregates

by Technical University MunichProposed mechanism and hypothetical models of IAPP/ACM nanofiber co-assembly versus IAPP amyloid self-assembly. The lower part, IAPP self-assembly into toxic oligome

Updated on: April 08,2024

Alzheimer's disease and type 2 diabetes: Synthetic peptides may suppress formation of harmful amyloid aggregates

by Technical University MunichProposed mechanism and hypothetical models of IAPP/ACM nanofiber co-assembly versus IAPP amyloid self-assembly. The lower part, IAPP self-assembly into toxic oligome

Updated on:April 08,2024

Recorded deaths from dementia more than double in 13 years

by Gisela Valencia,Alzheimer's Research UKNew figures released today show the proportion of people dying with a diagnosis of dementia more than doubled in 13 years. According to reports publ

Updated on: March 07,2024

Recorded deaths from dementia more than double in 13 years

by Gisela Valencia,Alzheimer's Research UKNew figures released today show the proportion of people dying with a diagnosis of dementia more than doubled in 13 years. According to reports publ

Updated on:March 07,2024

New imaging method illuminates oxygen's journey in the brain

by University of Rochester Medical CenterLuminescent protein, substrate, and oxygen all combine to create chemical chain reaction to produce light. Images shows the cortex of a mouse recorded ove

Updated on: March 30,2024

New imaging method illuminates oxygen's journey in the brain

by University of Rochester Medical CenterLuminescent protein, substrate, and oxygen all combine to create chemical chain reaction to produce light. Images shows the cortex of a mouse recorded ove

Updated on:March 30,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on: March 30,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on:March 30,2024

Excess body fat tied to lower cognitive scores in adults

(HealthDay)—Both generalized and visceral adiposity are associated with lower cognitive scores throughout midlife, according to a study published online Feb. 1 inJAMA Network Open.Sonia S. Anand

Updated on: February 05,2024

Excess body fat tied to lower cognitive scores in adults

(HealthDay)—Both generalized and visceral adiposity are associated with lower cognitive scores throughout midlife, according to a study published online Feb. 1 inJAMA Network Open.Sonia S. Anand

Updated on:February 05,2024

Alzheimer's disease consists of three distinct subtypes, according to study

by Kim Irwin,University of California, Los AngelesDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Alzheimer's disease, long thought to be a sin

Updated on: February 26,2024

Alzheimer's disease consists of three distinct subtypes, according to study

by Kim Irwin,University of California, Los AngelesDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Alzheimer's disease, long thought to be a sin

Updated on:February 26,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

How the brain remembers where you're going

by Julia Weiler, Donata Zuber,Ruhr-Universitaet-BochumCredit: CC0 Public DomainResearchers have made new discoveries about how certain brainwaves aid navigation. They hope that the methods may b

Updated on: May 18,2024

How the brain remembers where you're going

by Julia Weiler, Donata Zuber,Ruhr-Universitaet-BochumCredit: CC0 Public DomainResearchers have made new discoveries about how certain brainwaves aid navigation. They hope that the methods may b

Updated on:May 18,2024

Could blood pressure drugs have a role in Alzheimer's disease treatment?

by Georgetown University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In laboratory neuronal cultures, an FDA-approved drug used to

Updated on: February 27,2024

Could blood pressure drugs have a role in Alzheimer's disease treatment?

by Georgetown University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In laboratory neuronal cultures, an FDA-approved drug used to

Updated on:February 27,2024

Biochemical clues may predict who develops Alzheimer's disease—and who doesn't

by ElsevierDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Investigators have wondered why the brains of some cognitively-intact elderly individuals

Updated on: February 27,2024

Biochemical clues may predict who develops Alzheimer's disease—and who doesn't

by ElsevierDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Investigators have wondered why the brains of some cognitively-intact elderly individuals

Updated on:February 27,2024

People with cluster headaches may have a significantly increased risk of other illnesses

by American Academy of NeurologyCredit: CC0 Public DomainPeople with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental diso

Updated on: February 18,2024

People with cluster headaches may have a significantly increased risk of other illnesses

by American Academy of NeurologyCredit: CC0 Public DomainPeople with cluster headaches may be more than three times more likely to have other medical conditions such as heart disease, mental diso

Updated on:February 18,2024