A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

New imaging method illuminates oxygen's journey in the brain

by University of Rochester Medical CenterLuminescent protein, substrate, and oxygen all combine to create chemical chain reaction to produce light. Images shows the cortex of a mouse recorded ove

Updated on: March 30,2024

New imaging method illuminates oxygen's journey in the brain

by University of Rochester Medical CenterLuminescent protein, substrate, and oxygen all combine to create chemical chain reaction to produce light. Images shows the cortex of a mouse recorded ove

Updated on:March 30,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on: March 07,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on:March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Schizophrenia linked to increased risk for subsequent CVD events

MARCH 1, 2024by Elana GotkineSchizophrenia is associated with an increased risk of subsequent cardiovascular disease (CVD) events, with the association stronger in women, according to a study publishe

Updated on: March 13,2024

Schizophrenia linked to increased risk for subsequent CVD events

MARCH 1, 2024by Elana GotkineSchizophrenia is associated with an increased risk of subsequent cardiovascular disease (CVD) events, with the association stronger in women, according to a study publishe

Updated on:March 13,2024

Higher antioxidant levels linked to lower dementia risk

by American Academy of NeurologyCredit: CC0 Public DomainPeople with higher levels of antioxidants in their blood may be less likely to develop dementia, according to a study published in the May

Updated on: June 24,2024

Higher antioxidant levels linked to lower dementia risk

by American Academy of NeurologyCredit: CC0 Public DomainPeople with higher levels of antioxidants in their blood may be less likely to develop dementia, according to a study published in the May

Updated on:June 24,2024

Maintaining heart health may protect against cognitive decline

by American College of CardiologyCredit: CC0 Public DomainPeople with a higher risk of developing cardiovascular disease have increased cognitive decline, including an increase in typical markers

Updated on: April 29,2024

Maintaining heart health may protect against cognitive decline

by American College of CardiologyCredit: CC0 Public DomainPeople with a higher risk of developing cardiovascular disease have increased cognitive decline, including an increase in typical markers

Updated on:April 29,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on: March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on:March 28,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on: March 07,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on:March 07,2024

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on: February 26,2024

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on:February 26,2024

Daytime sleepiness linked to Alzheimer's

by From Mayo Clinic News Network, Mayo Clinic News NetworkPET scan of a human brain with Alzheimer's disease. Credit: public domainDo you catch yourself yawning during the day and yearning for an

Updated on: April 25,2024

Daytime sleepiness linked to Alzheimer's

by From Mayo Clinic News Network, Mayo Clinic News NetworkPET scan of a human brain with Alzheimer's disease. Credit: public domainDo you catch yourself yawning during the day and yearning for an

Updated on:April 25,2024