FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on: March 02,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on:March 02,2024

Progranulin and dementia—a blood sample does not tell the full story!

by Bentham Science PublishersProgranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal

Updated on: March 07,2024

Progranulin and dementia—a blood sample does not tell the full story!

by Bentham Science PublishersProgranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal

Updated on:March 07,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on: March 07,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on:March 07,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on: July 17,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on:July 17,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on: May 13,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on:May 13,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on: March 09,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on:March 09,2024

Scientists say Alzheimer's is probably a collection of diseases that should be classified and treated separately

by Hebrew University of JerusalemDeciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of

Updated on: February 26,2024

Scientists say Alzheimer's is probably a collection of diseases that should be classified and treated separately

by Hebrew University of JerusalemDeciphering the mechanism that underlies the development of Alzheimer's disease in certain families but not in others, researchers at the Hebrew University of

Updated on:February 26,2024

New blood test for Alzheimer's developed

by Margareta G. Kubista,University of GothenburgCredit: CC0 Public DomainA new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of

Updated on: April 18,2024

New blood test for Alzheimer's developed

by Margareta G. Kubista,University of GothenburgCredit: CC0 Public DomainA new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of

Updated on:April 18,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on: May 06,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on:May 06,2024