Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on: April 16,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on:April 16,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on: March 02,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on:March 02,2024

Mechanisms of phototherapy of Alzheimer's disease during sleep and wakefulness

by Frontiers JournalsPhotobiomodulation of brain cleansing of beta-amyloid during sleep. Credit: Frontiers JournalsPhotobiomodulation during sleep turns the brain into a washing machine, helping to cl

Updated on: March 02,2024

Mechanisms of phototherapy of Alzheimer's disease during sleep and wakefulness

by Frontiers JournalsPhotobiomodulation of brain cleansing of beta-amyloid during sleep. Credit: Frontiers JournalsPhotobiomodulation during sleep turns the brain into a washing machine, helping to cl

Updated on:March 02,2024

When memory loss should concern you

by Lauren Woods,University of ConnecticutCredit: AI-generated imageAlthough there is currently no cure for Alzheimer's Disease, Dr. Patrick Coll of UConn's Center on Aging recommends ear

Updated on: February 27,2024

When memory loss should concern you

by Lauren Woods,University of ConnecticutCredit: AI-generated imageAlthough there is currently no cure for Alzheimer's Disease, Dr. Patrick Coll of UConn's Center on Aging recommends ear

Updated on:February 27,2024

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on: February 28,2024

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on:February 28,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Could there be a link between the enteric neurons, gut microbiome and ALS?

by University of Illinois at ChicagoFigure 1. SOD1G93Amice have slow intestinal mobility, decreased rotarod test time and grip strength during ALS progression. (a) SOD1G93Amice signif

Updated on: February 05,2024

Could there be a link between the enteric neurons, gut microbiome and ALS?

by University of Illinois at ChicagoFigure 1. SOD1G93Amice have slow intestinal mobility, decreased rotarod test time and grip strength during ALS progression. (a) SOD1G93Amice signif

Updated on:February 05,2024

Discovery adds context to Alzheimer's fight

by Paul Mayne,University of Western OntarioRobarts Research Institute scientists Vania and Marco Prado have found a gene, TRPM2, that could be a therapeutic target to assist in decreasing cognit

Updated on: February 27,2024

Discovery adds context to Alzheimer's fight

by Paul Mayne,University of Western OntarioRobarts Research Institute scientists Vania and Marco Prado have found a gene, TRPM2, that could be a therapeutic target to assist in decreasing cognit

Updated on:February 27,2024

Exercising can protect the brain from Alzheimer's disease

by University of British ColumbiaKathleen Martin Ginis is a professor in UBC Okanagan's School of Heath and Exercise Sciences. Credit: UBC OkanaganThe evidence is clear. Physical activity is

Updated on: March 09,2024

Exercising can protect the brain from Alzheimer's disease

by University of British ColumbiaKathleen Martin Ginis is a professor in UBC Okanagan's School of Heath and Exercise Sciences. Credit: UBC OkanaganThe evidence is clear. Physical activity is

Updated on:March 09,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on: April 16,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on:April 16,2024

GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on: March 30,2024

GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on:March 30,2024

New device helps people with spinal cord injuries grasp large, heavy objects

by Marni Ellery,University of California - BerkeleyThe Dorsal Grasper assistive device, developed by UC Berkeley engineers, facilitates human-robot collaborative grasping. Credit: Adam Lau/Berke

Updated on: February 17,2025

New device helps people with spinal cord injuries grasp large, heavy objects

by Marni Ellery,University of California - BerkeleyThe Dorsal Grasper assistive device, developed by UC Berkeley engineers, facilitates human-robot collaborative grasping. Credit: Adam Lau/Berke

Updated on:February 17,2025