Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on: April 25,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on:April 25,2024

Researchers connect Alzheimer's-associated genetic variants with brain cell function

by University of North Carolina at Chapel Hill School of MedicineRepresentative immunofluorescence staining of microglia-specific marker IBA-1. Credit:Nature Genetics(2023). DOI: 10.1

Updated on: March 02,2024

Researchers connect Alzheimer's-associated genetic variants with brain cell function

by University of North Carolina at Chapel Hill School of MedicineRepresentative immunofluorescence staining of microglia-specific marker IBA-1. Credit:Nature Genetics(2023). DOI: 10.1

Updated on:March 02,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on: March 07,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on:March 07,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

Machine-learning algorithms used to detect Alzheimer's during phone conversations

by Bob Yirka , Medical XpressThe whole process in the present study. Credit: Shimoda et al, 2021 (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Researchers working at the Department of Public Health

Updated on: June 14,2024

Machine-learning algorithms used to detect Alzheimer's during phone conversations

by Bob Yirka , Medical XpressThe whole process in the present study. Credit: Shimoda et al, 2021 (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Researchers working at the Department of Public Health

Updated on:June 14,2024

An Alzheimer's treatment would tax the US health care system

by RAND CorporationThe flow of how an Alzheimer's treatment would get to patients after approval. Credit: RAND Corp.The U.S. health care system lacks the capacity to rapidly move a treatment

Updated on: April 08,2024

An Alzheimer's treatment would tax the US health care system

by RAND CorporationThe flow of how an Alzheimer's treatment would get to patients after approval. Credit: RAND Corp.The U.S. health care system lacks the capacity to rapidly move a treatment

Updated on:April 08,2024

Educational background and previous brain injury may be associated with higher risk of frontotemporal dementia

by University of Eastern FinlandCredit: Unsplash/CC0 Public DomainTwo recent studies from the University of Eastern Finland show that educational background and previous traumatic brain injury ma

Updated on: June 24,2024

Educational background and previous brain injury may be associated with higher risk of frontotemporal dementia

by University of Eastern FinlandCredit: Unsplash/CC0 Public DomainTwo recent studies from the University of Eastern Finland show that educational background and previous traumatic brain injury ma

Updated on:June 24,2024

A promising new approach to data sharing in neuroscience research

byHoward Hughes Medical InstituteOverview of Spyglass. Credit:(2024). DOI: 10.1101/2024.01.25.577295Loren Frank's HHMI lab at UCSF has pioneered an ambitious framework for sharing vast

Updated on: March 28,2024

A promising new approach to data sharing in neuroscience research

byHoward Hughes Medical InstituteOverview of Spyglass. Credit:(2024). DOI: 10.1101/2024.01.25.577295Loren Frank's HHMI lab at UCSF has pioneered an ambitious framework for sharing vast

Updated on:March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on: March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on:March 28,2024

Spinal fluid of people with Alzheimer's risk gene signals inflammation

by Duke University Medical CenterCredit: Pixabay/CC0 Public DomainPeople who have a gene variant associated with an increased risk of developing Alzheimer's disease also tend to have changes

Updated on: April 20,2024

Spinal fluid of people with Alzheimer's risk gene signals inflammation

by Duke University Medical CenterCredit: Pixabay/CC0 Public DomainPeople who have a gene variant associated with an increased risk of developing Alzheimer's disease also tend to have changes

Updated on:April 20,2024

Most Medicare beneficiaries say they don't receive cognitive assessments

by Orli Belman,University of Southern CaliforniaCredit: CC0 Public DomainNew research from the University of Southern California measured the use of Medicaid's annual wellness visits and the

Updated on: May 13,2024

Most Medicare beneficiaries say they don't receive cognitive assessments

by Orli Belman,University of Southern CaliforniaCredit: CC0 Public DomainNew research from the University of Southern California measured the use of Medicaid's annual wellness visits and the

Updated on:May 13,2024