Family history linked to increased Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainResearchers in Utah have found that people who have relatives who died of Alzheimer's are more likely to develop the disease. The findin

Updated on: June 20,2024

Family history linked to increased Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainResearchers in Utah have found that people who have relatives who died of Alzheimer's are more likely to develop the disease. The findin

Updated on:June 20,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on: September 23,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on:September 23,2024

Sets of neurons work in sync to track 'time' and 'place,' giving humans context for past, present and future

byUniversity of California, Los AngelesGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113238Two studies led by UCLA researchers offer new insights into the

Updated on: January 12,2024

Sets of neurons work in sync to track 'time' and 'place,' giving humans context for past, present and future

byUniversity of California, Los AngelesGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113238Two studies led by UCLA researchers offer new insights into the

Updated on:January 12,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

Vitamin D supplementation could reduce migraine headache attacks

(HealthDay)—Vitamin D supplementation could reduce headache attacks per month and headache days per month among migraine patients, according to a review published in the December issue ofThe Ame

Updated on: February 05,2024

Vitamin D supplementation could reduce migraine headache attacks

(HealthDay)—Vitamin D supplementation could reduce headache attacks per month and headache days per month among migraine patients, according to a review published in the December issue ofThe Ame

Updated on:February 05,2024

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on: February 03,2024

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on:February 03,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on: January 12,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on:January 12,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on: February 18,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on:February 18,2024

Understanding and Treating Parkinson's Disease: Unraveling Molecular Signals and Therapeutic Strategies

Updated on: May 17,2024

Understanding and Treating Parkinson's Disease: Unraveling Molecular Signals and Therapeutic Strategies

Updated on:May 17,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024