Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on: January 12,2024

Novel cause of brain mosaicism and focal epilepsy identified

byNationwide Children's HospitalBrain mosaic copy number gain of chr1q.a, Six patients included in the study met the following criteria: infantile spasms progressing to intractable foc

Updated on:January 12,2024

How heavy alcohol consumption increases brain inflammation

by The Scripps Research InstituteResearchers discovered higher than usual levels of the immune signaling molecule interleukin 1β (green) in neurons (outlined in red) from the brains of alcohol-de

Updated on: February 18,2024

How heavy alcohol consumption increases brain inflammation

by The Scripps Research InstituteResearchers discovered higher than usual levels of the immune signaling molecule interleukin 1β (green) in neurons (outlined in red) from the brains of alcohol-de

Updated on:February 18,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on: March 24,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on:March 24,2024

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on: February 21,2024

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on:February 21,2024

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu

Updated on: June 11,2024

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu

Updated on:June 11,2024

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on: April 16,2024

Alzheimer's: Nicotinic receptors as a new therapeutic target

by Institut PasteurRepresentation of space in the nicotinic receptor. Credit: Institut PasteurSeveral scientific studies have indicated that nicotine may be beneficial for memory function. Scientists

Updated on:April 16,2024

Mice with frequent flier miles advance the Alzheimer's cause

by University of KentuckyOlivier Thibault's lab at UK uses calcium imaging techniques to measure how neurons are affected over time. Thibault leads one of four groups in a multi-center grant

Updated on: June 01,2024

Mice with frequent flier miles advance the Alzheimer's cause

by University of KentuckyOlivier Thibault's lab at UK uses calcium imaging techniques to measure how neurons are affected over time. Thibault leads one of four groups in a multi-center grant

Updated on:June 01,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Breakthrough in understanding the cause of a rare and life-threatening condition related to sleep apnea

byBen-Gurion University of the NegevGraphical abstract. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-023-00018-9Ben-Gurion University (BGU) of the Negev's Prof. Gad Vatine

Updated on: April 23,2024

Breakthrough in understanding the cause of a rare and life-threatening condition related to sleep apnea

byBen-Gurion University of the NegevGraphical abstract. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-023-00018-9Ben-Gurion University (BGU) of the Negev's Prof. Gad Vatine

Updated on:April 23,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on: January 11,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on:January 11,2024

Striking changes to metal levels discovered in brain tissue of patients with Huntington's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainScientists from The Universities of Manchester and Auckland have discovered widespread differences in metal levels in th

Updated on: January 12,2024

Striking changes to metal levels discovered in brain tissue of patients with Huntington's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainScientists from The Universities of Manchester and Auckland have discovered widespread differences in metal levels in th

Updated on:January 12,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on: January 12,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on:January 12,2024