Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Helping dementia carers make sense of their experiences

by Cardiff UniversityCredit: Cardiff UniversityA powerful new animation produced by Cardiff University and narrated by Sir Tony Robinson has laid bare the communication difficulties facing people

Updated on: April 25,2024

Helping dementia carers make sense of their experiences

by Cardiff UniversityCredit: Cardiff UniversityA powerful new animation produced by Cardiff University and narrated by Sir Tony Robinson has laid bare the communication difficulties facing people

Updated on:April 25,2024

Neurological research provides molecular insights into the blood–brain barrier

by Liu Jia,Chinese Academy of SciencesGraphical abstract of this study. Credit: Prof. Chang, fromCell Reports(2023). DOI: 10.1016/j.celrep.2023.113392A team of researchers from the S

Updated on: February 26,2024

Neurological research provides molecular insights into the blood–brain barrier

by Liu Jia,Chinese Academy of SciencesGraphical abstract of this study. Credit: Prof. Chang, fromCell Reports(2023). DOI: 10.1016/j.celrep.2023.113392A team of researchers from the S

Updated on:February 26,2024

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on: June 15,2024

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on:June 15,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on: March 30,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on:March 30,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on: January 11,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on:January 11,2024

Survey shows lack of brain health awareness among women

by Cleveland ClinicCredit: Cleveland ClinicNearly two-thirds of Americans with Alzheimer's disease are women, but according to a Women's Alzheimer's Movement at Cleveland Clinic surve

Updated on: May 22,2024

Survey shows lack of brain health awareness among women

by Cleveland ClinicCredit: Cleveland ClinicNearly two-thirds of Americans with Alzheimer's disease are women, but according to a Women's Alzheimer's Movement at Cleveland Clinic surve

Updated on:May 22,2024

Big data analysis powers the fight against Alzheimer's

by Rita Steyn,Pacific Northwest National LaboratoryA PNNL technician studies a brain tissue sample. Credit: Andrea Starr / Pacific Northwest National LaboratoryAlzheimer's disease has always

Updated on: May 22,2024

Big data analysis powers the fight against Alzheimer's

by Rita Steyn,Pacific Northwest National LaboratoryA PNNL technician studies a brain tissue sample. Credit: Andrea Starr / Pacific Northwest National LaboratoryAlzheimer's disease has always

Updated on:May 22,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on: January 12,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on:January 12,2024

Surprising finding links sleep, brain insulation and neurodegeneration

by Allison Whitten,Stanford UniversityCredit:Neuron(2023). DOI: 10.1016/j.neuron.2023.08.002Scientists affiliated with the Knight Initiative for Brain Resilience at Wu Tsai Neuro hav

Updated on: January 12,2024

Surprising finding links sleep, brain insulation and neurodegeneration

by Allison Whitten,Stanford UniversityCredit:Neuron(2023). DOI: 10.1016/j.neuron.2023.08.002Scientists affiliated with the Knight Initiative for Brain Resilience at Wu Tsai Neuro hav

Updated on:January 12,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on: March 28,2024

New studies suggest millions with mild cognitive impairment go undiagnosed, often until it's too late

by Soeren Mattke and Ying Liu,The ConversationCredit: Pixabay/CC0 Public DomainMild cognitive impairment—an early stage of dementia—is widely underdiagnosed in people 65 and older. That is the k

Updated on:March 28,2024