Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024

More appropriate support is needed for older residents with dementia in subsidized housing

by University of TorontoCredit: Pixabay/CC0 Public DomainA recent scoping review, published online in theJournal of Aging and Environment, found that older adults with dementia or cognitive

Updated on: May 26,2024

More appropriate support is needed for older residents with dementia in subsidized housing

by University of TorontoCredit: Pixabay/CC0 Public DomainA recent scoping review, published online in theJournal of Aging and Environment, found that older adults with dementia or cognitive

Updated on:May 26,2024

Epigenetic markers associated with Alzheimer's disease found

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers from the Brigham and Women's Hospital, Harvard Medical School and the Dana-Farber Cancer Institute in the U.S., and Shan

Updated on: June 01,2024

Epigenetic markers associated with Alzheimer's disease found

by Bob Yirka , Medical XpressCredit: CC0 Public DomainA team of researchers from the Brigham and Women's Hospital, Harvard Medical School and the Dana-Farber Cancer Institute in the U.S., and Shan

Updated on:June 01,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on: February 18,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on:February 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on: June 01,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on:June 01,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

Too few seniors are getting their memory tested

by Serena Gordon, Healthday Reporter(HealthDay)—Most seniors expect their doctor to recommend testing of thinking and memory when it's needed.But a new survey discovered that is rarely the case: O

Updated on: June 07,2024

Too few seniors are getting their memory tested

by Serena Gordon, Healthday Reporter(HealthDay)—Most seniors expect their doctor to recommend testing of thinking and memory when it's needed.But a new survey discovered that is rarely the case: O

Updated on:June 07,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on: March 02,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on:March 02,2024

Scientists explain how the brain encodes lottery values

bySainsbury Wellcome CentreCartoon of a rat playing a game involving risk. Credit: The image was created with the assistance of AI (DALL·E 3)Neuroscientists have uncovered a key brain area in ra

Updated on: January 11,2024

Scientists explain how the brain encodes lottery values

bySainsbury Wellcome CentreCartoon of a rat playing a game involving risk. Credit: The image was created with the assistance of AI (DALL·E 3)Neuroscientists have uncovered a key brain area in ra

Updated on:January 11,2024

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on: February 03,2024

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on:February 03,2024