Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on: June 14,2024

Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on:June 14,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on: January 12,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on:January 12,2024

Neurological research provides molecular insights into the blood–brain barrier

by Liu Jia,Chinese Academy of SciencesGraphical abstract of this study. Credit: Prof. Chang, fromCell Reports(2023). DOI: 10.1016/j.celrep.2023.113392A team of researchers from the S

Updated on: February 26,2024

Neurological research provides molecular insights into the blood–brain barrier

by Liu Jia,Chinese Academy of SciencesGraphical abstract of this study. Credit: Prof. Chang, fromCell Reports(2023). DOI: 10.1016/j.celrep.2023.113392A team of researchers from the S

Updated on:February 26,2024

Machine learning can identify signs of Alzheimer's in patients recalling the story of Cinderella

by St. George's University of LondonCredit: Photo by Robina Weermeijer on Unsplash.A new study by researchers from the Neurosciences Research Centre at St George's has identified the stre

Updated on: June 11,2024

Machine learning can identify signs of Alzheimer's in patients recalling the story of Cinderella

by St. George's University of LondonCredit: Photo by Robina Weermeijer on Unsplash.A new study by researchers from the Neurosciences Research Centre at St George's has identified the stre

Updated on:June 11,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on: January 11,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on:January 11,2024

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on: March 28,2024

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on:March 28,2024

New tool can detect tiny protein clumps associated with neurodegenerative disorders

by University of CopenhagenInsulin proteins clumping together. Credit: Jacob Kæstel-HansenThe clumping of proteins is at the root of a wide range of neurodegenerative disorders that affect the br

Updated on: June 15,2024

New tool can detect tiny protein clumps associated with neurodegenerative disorders

by University of CopenhagenInsulin proteins clumping together. Credit: Jacob Kæstel-HansenThe clumping of proteins is at the root of a wide range of neurodegenerative disorders that affect the br

Updated on:June 15,2024

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu

Updated on: June 11,2024

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu

Updated on:June 11,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Breakthrough in understanding the cause of a rare and life-threatening condition related to sleep apnea

byBen-Gurion University of the NegevGraphical abstract. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-023-00018-9Ben-Gurion University (BGU) of the Negev's Prof. Gad Vatine

Updated on: April 23,2024

Breakthrough in understanding the cause of a rare and life-threatening condition related to sleep apnea

byBen-Gurion University of the NegevGraphical abstract. Credit:The EMBO Journal(2024). DOI: 10.1038/s44318-023-00018-9Ben-Gurion University (BGU) of the Negev's Prof. Gad Vatine

Updated on:April 23,2024

Experiments on mice reveal the parts of the brain involved in motion sickness

by Bob Yirka , Medical XpressIdentification of glutamatergic neuronal subpopulations in the VN. (A)Slc17a6Cremice were bilaterally injected in the VN with a viral vector expressing the Rib

Updated on: January 11,2024

Experiments on mice reveal the parts of the brain involved in motion sickness

by Bob Yirka , Medical XpressIdentification of glutamatergic neuronal subpopulations in the VN. (A)Slc17a6Cremice were bilaterally injected in the VN with a viral vector expressing the Rib

Updated on:January 11,2024