Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024

Is risk of Alzheimer's linked to specific sleep patterns?

by American Academy of NeurologyPET scan of a human brain with Alzheimer's disease. Credit: public domainDisturbed sleep patterns do not cause Alzheimer's disease but people who are at hi

Updated on: June 07,2024

Is risk of Alzheimer's linked to specific sleep patterns?

by American Academy of NeurologyPET scan of a human brain with Alzheimer's disease. Credit: public domainDisturbed sleep patterns do not cause Alzheimer's disease but people who are at hi

Updated on:June 07,2024

Family history linked to increased Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainResearchers in Utah have found that people who have relatives who died of Alzheimer's are more likely to develop the disease. The findin

Updated on: June 20,2024

Family history linked to increased Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainResearchers in Utah have found that people who have relatives who died of Alzheimer's are more likely to develop the disease. The findin

Updated on:June 20,2024

More education may not protect against dementia

by Universität Duisburg-EssenCredit: CC0 Public DomainThe state of knowledge seemed clear: school education protects against dementia. Every school year is supposed to reduce the risk of developing de

Updated on: June 05,2024

More education may not protect against dementia

by Universität Duisburg-EssenCredit: CC0 Public DomainThe state of knowledge seemed clear: school education protects against dementia. Every school year is supposed to reduce the risk of developing de

Updated on:June 05,2024

Scientists explain how the brain encodes lottery values

bySainsbury Wellcome CentreCartoon of a rat playing a game involving risk. Credit: The image was created with the assistance of AI (DALL·E 3)Neuroscientists have uncovered a key brain area in ra

Updated on: January 11,2024

Scientists explain how the brain encodes lottery values

bySainsbury Wellcome CentreCartoon of a rat playing a game involving risk. Credit: The image was created with the assistance of AI (DALL·E 3)Neuroscientists have uncovered a key brain area in ra

Updated on:January 11,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on: February 18,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on:February 18,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on: March 26,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on:March 26,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on: March 02,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on:March 02,2024

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on: February 03,2024

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on:February 03,2024

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on: February 03,2024

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on:February 03,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on: November 28,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on:November 28,2024