Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Insulin resistance in shift workers not affected by melatonin treatment, finds study

by University of SurreyTime course of serum glucose and insulin concentrations during oral glucose tolerance testing in night shift workers at baseline, after 12 weeks, and after 24 weeks as comp

Updated on: March 05,2024

Insulin resistance in shift workers not affected by melatonin treatment, finds study

by University of SurreyTime course of serum glucose and insulin concentrations during oral glucose tolerance testing in night shift workers at baseline, after 12 weeks, and after 24 weeks as comp

Updated on:March 05,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on: January 11,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on:January 11,2024

Researchers: Lifestyle changes can reduce dementia risk by maintaining brain plasticity, but the time to act is now

by Saskia Sivananthan and Laura Middleton,The ConversationCredit: CC0 Public DomainWalk 10,000 steps a day, cut back alcohol, get better sleep at night, stay socially active—we're told that

Updated on: February 24,2024

Researchers: Lifestyle changes can reduce dementia risk by maintaining brain plasticity, but the time to act is now

by Saskia Sivananthan and Laura Middleton,The ConversationCredit: CC0 Public DomainWalk 10,000 steps a day, cut back alcohol, get better sleep at night, stay socially active—we're told that

Updated on:February 24,2024

Research participation associated with greater adherence to medications for dementia, fewer racial disparities

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainNew research conducted by investigators from the Alzheimer's Disease Research Center at Mount Sinai has revealed that while older p

Updated on: May 05,2024

Research participation associated with greater adherence to medications for dementia, fewer racial disparities

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainNew research conducted by investigators from the Alzheimer's Disease Research Center at Mount Sinai has revealed that while older p

Updated on:May 05,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on: September 23,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on:September 23,2024

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved

Updated on: May 26,2024

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved

Updated on:May 26,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on: January 12,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on:January 12,2024

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on: February 21,2024

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on:February 21,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on: May 09,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on:May 09,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on: January 10,2024

Researchers detail mechanism of a key protein implicated in age-related brain dysfunction

byThe Mount Sinai HospitalAccumulation of extracellular matrix content in brain of TIMP2-deficient "KO" mice (left column) that leads to impaired plasticity processes, including the mi

Updated on:January 10,2024