Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Neurosurgeon explains the difference in brain aneurysms

by Deb Balzer, Mayo Clinic News NetworkCredit: CC0 Public DomainEach year, nearly half a million people worldwide die from brain aneurysms. In the U.S., an estimated 6.7 million people have an unruptu

Updated on: March 28,2024

Neurosurgeon explains the difference in brain aneurysms

by Deb Balzer, Mayo Clinic News NetworkCredit: CC0 Public DomainEach year, nearly half a million people worldwide die from brain aneurysms. In the U.S., an estimated 6.7 million people have an unruptu

Updated on:March 28,2024

How the brain coordinates speaking and breathing

by Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT researchers have discovered a brain circuit that drives vocalization and ensures that you talk only when you breathe o

Updated on: March 19,2024

How the brain coordinates speaking and breathing

by Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT researchers have discovered a brain circuit that drives vocalization and ensures that you talk only when you breathe o

Updated on:March 19,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on: January 11,2024

Post-COVID condition is not linked to ongoing infection or active brain damage, study shows

by Gustav Löfgren,Swedish Research CouncilPrincipal component analysis plot of 5 neurobiomarkers in CSF. The centroids for each group are indicated and surrounded with ellipses indicating 95% co

Updated on:January 11,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

Older adults with mild cognitive impairment may struggle with everyday decision-making

by Keck School of Medicine of USCCredit: CC0 Public DomainMild cognitive impairment (MCI) is a form of cognitive ability loss that can precede Alzheimer's disease or other types of dementia.

Updated on: June 11,2024

Older adults with mild cognitive impairment may struggle with everyday decision-making

by Keck School of Medicine of USCCredit: CC0 Public DomainMild cognitive impairment (MCI) is a form of cognitive ability loss that can precede Alzheimer's disease or other types of dementia.

Updated on:June 11,2024

Optimizing chronic subdural hematoma treatment

by Cactus CommunicationsThe MRCSDH is the first nationwide study in mainland China to assess the safety and efficacy of different treatment approaches for CSDH. Its findings can help the medical commu

Updated on: April 06,2024

Optimizing chronic subdural hematoma treatment

by Cactus CommunicationsThe MRCSDH is the first nationwide study in mainland China to assess the safety and efficacy of different treatment approaches for CSDH. Its findings can help the medical commu

Updated on:April 06,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on: May 06,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on:May 06,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on: July 06,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on:July 06,2024

Study reveals how, when and where non-invasive brain stimulation influences neuronal activity and cognition

byMonash UniversityOverall response time modulations in humans and in monkeys. Credit:Brain(2024). DOI: 10.1093/brain/awae273Brain stimulation using electrodes placed on the head has

Updated on: September 23,2024

Study reveals how, when and where non-invasive brain stimulation influences neuronal activity and cognition

byMonash UniversityOverall response time modulations in humans and in monkeys. Credit:Brain(2024). DOI: 10.1093/brain/awae273Brain stimulation using electrodes placed on the head has

Updated on:September 23,2024

Touchscreens and milkshakes: Study reveals more about brain's reward systems

by Cam Buchan,University of Western OntarioThe touchscreen Autoshaping task to assess Pavlovian approach behaviors toward reward-predicting stimuli. a Layout of the Autoshaping touchscreen opera

Updated on: February 03,2024

Touchscreens and milkshakes: Study reveals more about brain's reward systems

by Cam Buchan,University of Western OntarioThe touchscreen Autoshaping task to assess Pavlovian approach behaviors toward reward-predicting stimuli. a Layout of the Autoshaping touchscreen opera

Updated on:February 03,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on: March 24,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on:March 24,2024