A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on: February 21,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on:February 21,2024

From molecular to whole-brain scale in a simple animal, study reveals serotonin's effects

byMassachusetts Institute of TechnologyA 3D rendering of a C. elegans worm, mapping all of its neurons. Credit: Steve Flavell/MIT Picower InstituteBecause serotonin is one of the primary chemica

Updated on: February 18,2024

From molecular to whole-brain scale in a simple animal, study reveals serotonin's effects

byMassachusetts Institute of TechnologyA 3D rendering of a C. elegans worm, mapping all of its neurons. Credit: Steve Flavell/MIT Picower InstituteBecause serotonin is one of the primary chemica

Updated on:February 18,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on: April 25,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on:April 25,2024

ANKRD55: A new gene involved in Multiple Sclerosis is discovered

by University of the Basque CountryThis image shows intracellular localization of ANKRD55 in Jurkat, SH-SY5Y and PMA-treated U937 cells. Credit: Koen VandenbroeckMultiple Sclerosis (MS) is a neur

Updated on: March 26,2024

ANKRD55: A new gene involved in Multiple Sclerosis is discovered

by University of the Basque CountryThis image shows intracellular localization of ANKRD55 in Jurkat, SH-SY5Y and PMA-treated U937 cells. Credit: Koen VandenbroeckMultiple Sclerosis (MS) is a neur

Updated on:March 26,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on: June 14,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on:June 14,2024

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on: June 15,2024

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on:June 15,2024

Neurosurgeon explains the difference in brain aneurysms

by Deb Balzer, Mayo Clinic News NetworkCredit: CC0 Public DomainEach year, nearly half a million people worldwide die from brain aneurysms. In the U.S., an estimated 6.7 million people have an unruptu

Updated on: March 28,2024

Neurosurgeon explains the difference in brain aneurysms

by Deb Balzer, Mayo Clinic News NetworkCredit: CC0 Public DomainEach year, nearly half a million people worldwide die from brain aneurysms. In the U.S., an estimated 6.7 million people have an unruptu

Updated on:March 28,2024

Brain imaging of tau protein in patients with various forms of dementia

by Cell PressThis figure shows associations between the Clinical Disease Severity and the Extent of Areas Showing Increased 18F-PM-PBB3 Binding in the AD Spectrum. Credit: Tagai, Ono, and Kubota

Updated on: May 05,2024

Brain imaging of tau protein in patients with various forms of dementia

by Cell PressThis figure shows associations between the Clinical Disease Severity and the Extent of Areas Showing Increased 18F-PM-PBB3 Binding in the AD Spectrum. Credit: Tagai, Ono, and Kubota

Updated on:May 05,2024

Driving with dementia—New guidance for doctors

by Newcastle UniversityNew guidelines have been published to help doctors and health care professionals assess and manage when people living with dementia should stop driving. Credit: Newcastle U

Updated on: May 09,2024

Driving with dementia—New guidance for doctors

by Newcastle UniversityNew guidelines have been published to help doctors and health care professionals assess and manage when people living with dementia should stop driving. Credit: Newcastle U

Updated on:May 09,2024

Low-cost versatile mesoscope makes brain imaging in rodents more accessible

by SPIEThis newly developed modular mesoscope can be used for in vivo fluorescence imaging of rodent brains. It is versatile and can adjust to different experimental requirements while still prov

Updated on: March 19,2024

Low-cost versatile mesoscope makes brain imaging in rodents more accessible

by SPIEThis newly developed modular mesoscope can be used for in vivo fluorescence imaging of rodent brains. It is versatile and can adjust to different experimental requirements while still prov

Updated on:March 19,2024