Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on: April 25,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on:April 25,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on: April 16,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on:April 16,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on: May 06,2024

Broken brain cells repaired in dementia mouse model

by Society for NeuroscienceRepresentative images of the hippocampus and Entorhinal cortex. Credit: Terreros-Roncal et al.JNeurosci(2019)Dysfunctional neurons in the hippocampus of adu

Updated on:May 06,2024

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on: March 25,2024

Molecular clusters on glial cells show they are more than our brain's 'glue'

FEBRUARY 28, 2024byFred Hutchinson Cancer CenterGraphical abstract. Credit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113844Neuroscientists at Fred Hutchinson Cancer Center have

Updated on:March 25,2024

Shorter telomeres point to increased Alzheimer's risk

by Kim Krieger,University of ConnecticutHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShort telomeres in midlife are associated with a higher risk of develo

Updated on: May 22,2024

Shorter telomeres point to increased Alzheimer's risk

by Kim Krieger,University of ConnecticutHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShort telomeres in midlife are associated with a higher risk of develo

Updated on:May 22,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on: January 09,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on:January 09,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on: April 26,2024

Study reveals insights into link between genetic mutation and Parkinson's

by Bill Hathaway,Yale UniversityLRRK2 inhibits lysosomal protease activity in human iPSC-derived macrophages. (A) Airyscan live cell confocal micrographs showing lysosome labeling in human iPSC-

Updated on:April 26,2024

Too few seniors are getting their memory tested

by Serena Gordon, Healthday Reporter(HealthDay)—Most seniors expect their doctor to recommend testing of thinking and memory when it's needed.But a new survey discovered that is rarely the case: O

Updated on: June 07,2024

Too few seniors are getting their memory tested

by Serena Gordon, Healthday Reporter(HealthDay)—Most seniors expect their doctor to recommend testing of thinking and memory when it's needed.But a new survey discovered that is rarely the case: O

Updated on:June 07,2024

Vitamin D supplementation could reduce migraine headache attacks

(HealthDay)—Vitamin D supplementation could reduce headache attacks per month and headache days per month among migraine patients, according to a review published in the December issue ofThe Ame

Updated on: February 05,2024

Vitamin D supplementation could reduce migraine headache attacks

(HealthDay)—Vitamin D supplementation could reduce headache attacks per month and headache days per month among migraine patients, according to a review published in the December issue ofThe Ame

Updated on:February 05,2024

Better than a hole in the head: Modernizing intracranial pressure sensing methods

by Sara Vaccar,Carnegie Mellon UniversityCredit: Carnegie Mellon UniversityJust as blood pressure informs heart health, intracranial pressure (ICP) helps indicate brain health. ICP sensing is th

Updated on: February 03,2024

Better than a hole in the head: Modernizing intracranial pressure sensing methods

by Sara Vaccar,Carnegie Mellon UniversityCredit: Carnegie Mellon UniversityJust as blood pressure informs heart health, intracranial pressure (ICP) helps indicate brain health. ICP sensing is th

Updated on:February 03,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on: February 26,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on:February 26,2024