Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu

Updated on: June 11,2024

Machine-learning program reveals genes responsible for sex-specific differences in Alzheimer's disease progression

by Texas Children's HospitalThe top 98 EAML genes are connected to GWAS genes, dysregulated in AD patients, and capable of separating AD and healthy control samples. Credit:Nature Commu

Updated on:June 11,2024

Research participation associated with greater adherence to medications for dementia, fewer racial disparities

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainNew research conducted by investigators from the Alzheimer's Disease Research Center at Mount Sinai has revealed that while older p

Updated on: May 05,2024

Research participation associated with greater adherence to medications for dementia, fewer racial disparities

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainNew research conducted by investigators from the Alzheimer's Disease Research Center at Mount Sinai has revealed that while older p

Updated on:May 05,2024

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on: April 20,2024

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on:April 20,2024

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on: March 19,2024

Study opens the door to earlier diagnosis and potential treatment for Alzheimer's disease

by Aarhus UniversityLarge Aβ Agg [+] MCI patients display lower AD-like brain pathology than large Aβ Agg [-] MCI.a18F-FTP PET uptake in each group at baseline, two-year follow-up, an

Updated on:March 19,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on: January 12,2024

Imprinted genes in the 'parenting hub' of the brain determine if mice are good parents, new study finds

byPublic Library of ScienceCredit: Pixabay/CC0 Public DomainWhether a mouse is a good or bad parent can be traced back to imprinted genes in key neurons in the "parenting hub" in the b

Updated on:January 12,2024

Surprising finding links sleep, brain insulation and neurodegeneration

by Allison Whitten,Stanford UniversityCredit:Neuron(2023). DOI: 10.1016/j.neuron.2023.08.002Scientists affiliated with the Knight Initiative for Brain Resilience at Wu Tsai Neuro hav

Updated on: January 12,2024

Surprising finding links sleep, brain insulation and neurodegeneration

by Allison Whitten,Stanford UniversityCredit:Neuron(2023). DOI: 10.1016/j.neuron.2023.08.002Scientists affiliated with the Knight Initiative for Brain Resilience at Wu Tsai Neuro hav

Updated on:January 12,2024

Machine learning can identify signs of Alzheimer's in patients recalling the story of Cinderella

by St. George's University of LondonCredit: Photo by Robina Weermeijer on Unsplash.A new study by researchers from the Neurosciences Research Centre at St George's has identified the stre

Updated on: June 11,2024

Machine learning can identify signs of Alzheimer's in patients recalling the story of Cinderella

by St. George's University of LondonCredit: Photo by Robina Weermeijer on Unsplash.A new study by researchers from the Neurosciences Research Centre at St George's has identified the stre

Updated on:June 11,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on: June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on:June 07,2024

How human and dog interactions affect the brain

byWileyCredit: Pixabay/CC0 Public DomainDuring social interactions, the activity of the brain's neurons becomes synchronized between the individuals involved. New researchpublished&nbs

Updated on: September 23,2024

How human and dog interactions affect the brain

byWileyCredit: Pixabay/CC0 Public DomainDuring social interactions, the activity of the brain's neurons becomes synchronized between the individuals involved. New researchpublished&nbs

Updated on:September 23,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on: February 05,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on:February 05,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024