Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on: February 24,2024

Researchers identify a new small molecule inhibitor for use against Alzheimer's disease

by Brandon Chase,Massachusetts General HospitalChemical properties, and synthesis of PB118. Credit:Advanced Science(2023). DOI: 10.1002/advs.202304545In people with Alzheimer's d

Updated on:February 24,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024

Striking changes to metal levels discovered in brain tissue of patients with Huntington's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainScientists from The Universities of Manchester and Auckland have discovered widespread differences in metal levels in th

Updated on: January 12,2024

Striking changes to metal levels discovered in brain tissue of patients with Huntington's disease

by Mike Addelman,University of ManchesterCredit: Pixabay/CC0 Public DomainScientists from The Universities of Manchester and Auckland have discovered widespread differences in metal levels in th

Updated on:January 12,2024

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on: February 03,2024

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on:February 03,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on: February 21,2024

Secret structure in the wiring diagram of the brain

by Petra Sandow,University of BonnCredit: UKB & LMU / Dr. Nataliya Kraynyukova; Dr. Simon RennerIn the brain, our perception arises from a complex interplay of neurons that are connected via

Updated on:February 21,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on: May 09,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on:May 09,2024

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on: June 15,2024

Tips to making your home safer for people with Alzheimer's

by Ernie MundellBright lights, loud sounds and trip hazards can make a person with Alzheimer's uncomfortable in the home and even pose real dangers.The Alzheimer's Foundation of America (AFA)

Updated on:June 15,2024

Prospects continue to improve for people with MS, but disease management in older adults presents challenges

by Ellen Goldbaum,University at BuffaloCredit: Anna Shvets from PexelsThe past five years have seen significant advancements in diagnosing and treating multiple sclerosis (MS), but challenges re

Updated on: January 10,2024

Prospects continue to improve for people with MS, but disease management in older adults presents challenges

by Ellen Goldbaum,University at BuffaloCredit: Anna Shvets from PexelsThe past five years have seen significant advancements in diagnosing and treating multiple sclerosis (MS), but challenges re

Updated on:January 10,2024

Family history linked to increased Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainResearchers in Utah have found that people who have relatives who died of Alzheimer's are more likely to develop the disease. The findin

Updated on: June 20,2024

Family history linked to increased Alzheimer's risk

by Alzheimer's Research UKCredit: CC0 Public DomainResearchers in Utah have found that people who have relatives who died of Alzheimer's are more likely to develop the disease. The findin

Updated on:June 20,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on: March 02,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on:March 02,2024