C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on: March 26,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on:March 26,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on: April 28,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on:April 28,2024

How sensory neurons impact the gut

by The Scripps Research InstituteResearchers showed that PIEZO2 receptors in sensory neurons control the rate of gut transit. In this fluorescently stained microscopy image, nerve endings stemmin

Updated on: June 20,2024

How sensory neurons impact the gut

by The Scripps Research InstituteResearchers showed that PIEZO2 receptors in sensory neurons control the rate of gut transit. In this fluorescently stained microscopy image, nerve endings stemmin

Updated on:June 20,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on: November 28,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on:November 28,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on: April 07,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on:April 07,2024

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on: March 28,2024

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on:March 28,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on: January 11,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on:January 11,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on: May 20,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on:May 20,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on: February 03,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on:February 03,2024

Giving common muscle relaxant via nose shows potential to treat neurodegenerative diseases

by Perelman School of Medicine at the University of PennsylvaniaPET scan of a human brain with Alzheimer's disease. Credit: public domainDelivering the medication dantrolene through the nose

Updated on: July 01,2024

Giving common muscle relaxant via nose shows potential to treat neurodegenerative diseases

by Perelman School of Medicine at the University of PennsylvaniaPET scan of a human brain with Alzheimer's disease. Credit: public domainDelivering the medication dantrolene through the nose

Updated on:July 01,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on: June 01,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on:June 01,2024