New tool can detect tiny protein clumps associated with neurodegenerative disorders

by University of CopenhagenInsulin proteins clumping together. Credit: Jacob Kæstel-HansenThe clumping of proteins is at the root of a wide range of neurodegenerative disorders that affect the br

Updated on: June 15,2024

New tool can detect tiny protein clumps associated with neurodegenerative disorders

by University of CopenhagenInsulin proteins clumping together. Credit: Jacob Kæstel-HansenThe clumping of proteins is at the root of a wide range of neurodegenerative disorders that affect the br

Updated on:June 15,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

New study reveals how the brain orchestrates motions in partnership with sensory cues from the body

byColumbia UniversityMicroscope image of a fly brain (gray) with magenta visual neurons connecting to a motor neuron in this study (green). Credit: Stephen Huston, Zuckerman Institute; Rebecca J

Updated on: March 28,2024

New study reveals how the brain orchestrates motions in partnership with sensory cues from the body

byColumbia UniversityMicroscope image of a fly brain (gray) with magenta visual neurons connecting to a motor neuron in this study (green). Credit: Stephen Huston, Zuckerman Institute; Rebecca J

Updated on:March 28,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on: February 21,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on:February 21,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on: April 25,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on:April 25,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on: March 26,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on:March 26,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on: July 06,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on:July 06,2024

Scientists uncover the role of dopamine in mediating short-term and long-term memory dynamics

by Tejasri Gururaj , Medical XpressNeural activity gives information about how fruit flies respond to various sensory stimuli, revealing insights into how they process and encode these experiences int

Updated on: September 09,2024

Scientists uncover the role of dopamine in mediating short-term and long-term memory dynamics

by Tejasri Gururaj , Medical XpressNeural activity gives information about how fruit flies respond to various sensory stimuli, revealing insights into how they process and encode these experiences int

Updated on:September 09,2024

Sounding the alarm on a future Alzheimer's disease epidemic

by Carla Denly,University of California, Los AngelesWe're living longer. The number of U.S. adults 65 and older—roughly 40 million as of the 2010 census—is expected to nearly double to 71 mi

Updated on: February 27,2024

Sounding the alarm on a future Alzheimer's disease epidemic

by Carla Denly,University of California, Los AngelesWe're living longer. The number of U.S. adults 65 and older—roughly 40 million as of the 2010 census—is expected to nearly double to 71 mi

Updated on:February 27,2024

Having great-grandparents, cousins with Alzheimer's linked to higher risk

by American Academy of NeurologyCredit: CC0 Public DomainHaving a parent with Alzheimer's disease has been known to raise a person's risk of developing the disease, but new research sugge

Updated on: May 05,2024

Having great-grandparents, cousins with Alzheimer's linked to higher risk

by American Academy of NeurologyCredit: CC0 Public DomainHaving a parent with Alzheimer's disease has been known to raise a person's risk of developing the disease, but new research sugge

Updated on:May 05,2024

Hallucinations from flickering lights: What happens in our brain?

by Netherlands Institute for Neuroscience - KNAWCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.091A new study from the Netherlands Institute for Neuroscience shows how flickering

Updated on: September 23,2024

Hallucinations from flickering lights: What happens in our brain?

by Netherlands Institute for Neuroscience - KNAWCredit:Current Biology(2024). DOI: 10.1016/j.cub.2024.07.091A new study from the Netherlands Institute for Neuroscience shows how flickering

Updated on:September 23,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on: March 30,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on:March 30,2024