A new treatment reduces inflammation in multiple sclerosis mice models

by Autonomous University of BarcelonaMaR1 reduces pro-inflammatory cytokines in the spinal cord of EAE mice. Plot showing the fold change in cytokine protein levels of different cytokines in the

Updated on: March 25,2024

A new treatment reduces inflammation in multiple sclerosis mice models

by Autonomous University of BarcelonaMaR1 reduces pro-inflammatory cytokines in the spinal cord of EAE mice. Plot showing the fold change in cytokine protein levels of different cytokines in the

Updated on:March 25,2024

Low-cost versatile mesoscope makes brain imaging in rodents more accessible

by SPIEThis newly developed modular mesoscope can be used for in vivo fluorescence imaging of rodent brains. It is versatile and can adjust to different experimental requirements while still prov

Updated on: March 19,2024

Low-cost versatile mesoscope makes brain imaging in rodents more accessible

by SPIEThis newly developed modular mesoscope can be used for in vivo fluorescence imaging of rodent brains. It is versatile and can adjust to different experimental requirements while still prov

Updated on:March 19,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on: June 01,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on:June 01,2024

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on: February 28,2024

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on:February 28,2024

How touch dampens the brain's response to painful stimuli

by Jennifer Michalowski,Massachusetts Institute of TechnologyNeurons in the thalamus (green) project to the somatosensory cortex and relay tactile information. These neurons are required for tou

Updated on: February 05,2024

How touch dampens the brain's response to painful stimuli

by Jennifer Michalowski,Massachusetts Institute of TechnologyNeurons in the thalamus (green) project to the somatosensory cortex and relay tactile information. These neurons are required for tou

Updated on:February 05,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024

Important signs of blood clots in the lungs missed in patients with dementia

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainPatients with dementia who had signs and risk factors of a pulmonary embolism, or a blood clot in the lungs, were much les

Updated on: May 09,2024

Important signs of blood clots in the lungs missed in patients with dementia

by University of California, Los AngelesCredit: Pixabay/CC0 Public DomainPatients with dementia who had signs and risk factors of a pulmonary embolism, or a blood clot in the lungs, were much les

Updated on:May 09,2024

A new model to predict brain development

by Paris Brain InstituteRepresentation of the cerebral development in C. elegans as a statio-temporal topographical map. Credit: Vito Dichio, Fabrizio De Vico Fallani.From the very first weeks of

Updated on: March 19,2024

A new model to predict brain development

by Paris Brain InstituteRepresentation of the cerebral development in C. elegans as a statio-temporal topographical map. Credit: Vito Dichio, Fabrizio De Vico Fallani.From the very first weeks of

Updated on:March 19,2024

Researchers identify gene involved in neuronal vulnerability in Alzheimer's disease

by Boston University School of MedicineCredit: CC0 Public DomainEarly stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cell

Updated on: March 20,2024

Researchers identify gene involved in neuronal vulnerability in Alzheimer's disease

by Boston University School of MedicineCredit: CC0 Public DomainEarly stages of neurodegenerative disorders are characterized by the accumulation of proteins in discrete populations of brain cell

Updated on:March 20,2024

Anxiety associated with faster Alzheimer's disease onset

by Radiological Society of North AmericaBrain MRI of a 72-year-old woman shows loss of volume of the hippocampus (arrows). The patient had all three characteristics, volume loss of the hippocampi

Updated on: June 24,2024

Anxiety associated with faster Alzheimer's disease onset

by Radiological Society of North AmericaBrain MRI of a 72-year-old woman shows loss of volume of the hippocampus (arrows). The patient had all three characteristics, volume loss of the hippocampi

Updated on:June 24,2024

Alzheimer's breakthrough: Brain metals that may drive disease progression revealed

by University of WarwickIn brains affected by Alzheimer's, researchers identify chemically reduced iron species, with mineral forms including a magnetic iron oxide which they hypothesize are

Updated on: April 18,2024

Alzheimer's breakthrough: Brain metals that may drive disease progression revealed

by University of WarwickIn brains affected by Alzheimer's, researchers identify chemically reduced iron species, with mineral forms including a magnetic iron oxide which they hypothesize are

Updated on:April 18,2024

Researchers find connections between neuroinflammation and Alzheimer's disease

by Brigham and Women's HospitalINPP5D expression in the human brain is restricted to microglia in the human brain. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-4281

Updated on: June 19,2024

Researchers find connections between neuroinflammation and Alzheimer's disease

by Brigham and Women's HospitalINPP5D expression in the human brain is restricted to microglia in the human brain. Credit:Nature Communications(2023). DOI: 10.1038/s41467-023-4281

Updated on:June 19,2024