Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on: February 03,2024

Fearful memories of pain stored in the prefrontal cortex could shape the experience of pain later in life

by Ingrid Fadelli , Medical XpressViral-mediated, Dox-controlled expression of protein tags under the Fos promoter, leading to activity-dependent tagging of prelimbic neurons with mCherry following pa

Updated on:February 03,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Helping dementia carers make sense of their experiences

by Cardiff UniversityCredit: Cardiff UniversityA powerful new animation produced by Cardiff University and narrated by Sir Tony Robinson has laid bare the communication difficulties facing people

Updated on: April 25,2024

Helping dementia carers make sense of their experiences

by Cardiff UniversityCredit: Cardiff UniversityA powerful new animation produced by Cardiff University and narrated by Sir Tony Robinson has laid bare the communication difficulties facing people

Updated on:April 25,2024

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on: February 21,2024

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on:February 21,2024

Brain flexibility may hasten hearing improvements from cochlear implants

by NYU Langone HealthCredit: Pixabay/CC0 Public DomainKickstarting the brain's natural ability to adjust to new circumstances, or neuroplasticity, improves how effectively a cochlear implant

Updated on: February 21,2024

Brain flexibility may hasten hearing improvements from cochlear implants

by NYU Langone HealthCredit: Pixabay/CC0 Public DomainKickstarting the brain's natural ability to adjust to new circumstances, or neuroplasticity, improves how effectively a cochlear implant

Updated on:February 21,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on: January 11,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on:January 11,2024

Study uncovers multiple lineages of stem cells contributing to neuron production

by Elena Garrido,Miguel Hernandez University of ElcheDiversity of Radial Glia cells in the neonatal ferret cerebral cortex, labeled with green fluorescent protein and seen within the transparent

Updated on: April 27,2024

Study uncovers multiple lineages of stem cells contributing to neuron production

by Elena Garrido,Miguel Hernandez University of ElcheDiversity of Radial Glia cells in the neonatal ferret cerebral cortex, labeled with green fluorescent protein and seen within the transparent

Updated on:April 27,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on: March 07,2024

Personality changes don't precede clinical onset of Alzheimer's, study shows

by Doug Carlson,Florida State UniversityFor years, scientists and physicians have been debating whether personality and behavior changes might appear prior to the onset of Alzheimer's diseas

Updated on:March 07,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on: February 18,2024

Extraction of bouton-like structures from neuropil calcium imaging data

by The University of Electro-CommunicationsCalcium imaging of the VNC neuropil in an isolated CNS. (A) Schematics of the CNS, the VNC, the neuropil, and boutons in the Drosophila larvae. (B) Schematic

Updated on:February 18,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on: January 12,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on:January 12,2024