Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on: January 09,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on:January 09,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on: January 11,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on:January 11,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on: February 24,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on:February 24,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on: February 05,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on:February 05,2024

Negative wealth shock linked to accelerated cognitive decline

by Elana GotkineFor older adults, negative wealth shock is associated with accelerated cognitive decline and increased risks for dementia, according to a study published online Dec. 26 inJAMA Ne

Updated on: February 24,2024

Negative wealth shock linked to accelerated cognitive decline

by Elana GotkineFor older adults, negative wealth shock is associated with accelerated cognitive decline and increased risks for dementia, according to a study published online Dec. 26 inJAMA Ne

Updated on:February 24,2024

New findings on physical activity could shape treatment for mild Alzheimer's disease

by University of KansasResearchers say understanding daily patterns of physical activity could help design more effective interventions. Credit: KUFor older adults, physical activity is apt to sh

Updated on: June 05,2024

New findings on physical activity could shape treatment for mild Alzheimer's disease

by University of KansasResearchers say understanding daily patterns of physical activity could help design more effective interventions. Credit: KUFor older adults, physical activity is apt to sh

Updated on:June 05,2024

The biggest financial, legal and functional challenges of caregivers of persons living with dementia

by Ann Kellett,Texas A&M UniversityCredit: Pixabay/CC0 Public DomainAnew studypublished inJMIR Agingidentifies the major challenges and needs of the 11 million Americ

Updated on: March 02,2024

The biggest financial, legal and functional challenges of caregivers of persons living with dementia

by Ann Kellett,Texas A&M UniversityCredit: Pixabay/CC0 Public DomainAnew studypublished inJMIR Agingidentifies the major challenges and needs of the 11 million Americ

Updated on:March 02,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

'Curved' walking and a depth camera: New tool detects early cognitive decline

by Florida Atlantic UniversityMahmoud Seifallahi (seated) and Behnaz Ghoraani, Ph.D., reviewing walking performance using a depth camera, which can detect and track 25 joints of body movement. Cr

Updated on: March 19,2024

'Curved' walking and a depth camera: New tool detects early cognitive decline

by Florida Atlantic UniversityMahmoud Seifallahi (seated) and Behnaz Ghoraani, Ph.D., reviewing walking performance using a depth camera, which can detect and track 25 joints of body movement. Cr

Updated on:March 19,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on: February 26,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on:February 26,2024

Brain pathways that control dopamine release may influence motor control

by Anne Trafton,Massachusetts Institute of TechnologyStriosomal S-D1 and S-D2 populations form parallel pathways to dopamine-containing nigral neurons. Credit:Current Biology(2024).

Updated on: November 07,2024

Brain pathways that control dopamine release may influence motor control

by Anne Trafton,Massachusetts Institute of TechnologyStriosomal S-D1 and S-D2 populations form parallel pathways to dopamine-containing nigral neurons. Credit:Current Biology(2024).

Updated on:November 07,2024