Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Where you live may be associated with more successful stroke recovery

by American Heart AssociationCredit: Pixabay/CC0 Public DomainStroke survivors living in areas with poor economic conditions were twice as likely to have a poor recovery compared to survivors liv

Updated on: March 15,2024

Where you live may be associated with more successful stroke recovery

by American Heart AssociationCredit: Pixabay/CC0 Public DomainStroke survivors living in areas with poor economic conditions were twice as likely to have a poor recovery compared to survivors liv

Updated on:March 15,2024

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved

Updated on: May 26,2024

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved

Updated on:May 26,2024

New findings on physical activity could shape treatment for mild Alzheimer's disease

by University of KansasResearchers say understanding daily patterns of physical activity could help design more effective interventions. Credit: KUFor older adults, physical activity is apt to sh

Updated on: June 05,2024

New findings on physical activity could shape treatment for mild Alzheimer's disease

by University of KansasResearchers say understanding daily patterns of physical activity could help design more effective interventions. Credit: KUFor older adults, physical activity is apt to sh

Updated on:June 05,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on: September 23,2024

Advanced fMRI techniques reveal the brain's dynamic architecture

byMiguel Hernandez University of ElcheHierarchical distribution of connections represented in colors on the surface of a human brain. Credit: Varga, L. et al. inCell Systems(2024)Res

Updated on:September 23,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on: November 28,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on:November 28,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on: May 09,2024

Digital solutions for dementia care

by Flinders UniversityFlinders University Associate Professor Kate Laver, ARC Discovery Early Career Research Fellow and occupational therapist. Credit: Flinders UniversityTelehealth delivery of

Updated on:May 09,2024

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on: February 03,2024

Genes expressed in the brain before birth may affect risk of childhood mental illness

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have identified various genes whose expression in the brain before birth may affect the risk of developing a range of

Updated on:February 03,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Marriage is linked to reduced dementia risk

by Alzheimer's Research UKResearchers from University College London have found that people who are single or widowed are at a greater risk of dementia than people who are married. The resear

Updated on: March 07,2024

Marriage is linked to reduced dementia risk

by Alzheimer's Research UKResearchers from University College London have found that people who are single or widowed are at a greater risk of dementia than people who are married. The resear

Updated on:March 07,2024