Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on: April 07,2024

Alzheimer's pathology, not cognitive decline, drives neuropsychiatric symptoms

by ElsevierFigure 1. Linear Mixed Effect Models displaying effects of pathology at baseline over time on the development of neuropsychiatric symptoms Plots of estimated marginal means and 95% CI

Updated on:April 07,2024

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on: March 28,2024

Researchers make key improvements to Parkinson's disease cell therapies

JULY 13, 2023byMass General BrighamCredit: Pixabay/CC0 Public DomainCell therapy holds promise as a new treatment for Parkinson's disease but, in many trials to date, most transplanted dopam

Updated on:March 28,2024

Researchers: Lifestyle changes can reduce dementia risk by maintaining brain plasticity, but the time to act is now

by Saskia Sivananthan and Laura Middleton,The ConversationCredit: CC0 Public DomainWalk 10,000 steps a day, cut back alcohol, get better sleep at night, stay socially active—we're told that

Updated on: February 24,2024

Researchers: Lifestyle changes can reduce dementia risk by maintaining brain plasticity, but the time to act is now

by Saskia Sivananthan and Laura Middleton,The ConversationCredit: CC0 Public DomainWalk 10,000 steps a day, cut back alcohol, get better sleep at night, stay socially active—we're told that

Updated on:February 24,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on: May 20,2024

Over 1.2 million people in England and Wales will be living with dementia by 2040

by British Medical JournalCredit: CC0 Public DomainBy 2040, there will be over 1.2 million people living with dementia in England and Wales (an increase of 57% from 2016), largely due to increase

Updated on:May 20,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on: March 26,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on:March 26,2024

Mindset4Dementia app uses AI for next generation screening tool

by Kate Clark,University College LondonCredit: Pixabay/CC0 Public DomainA team of students and doctors, led by UCL medic Hamzah Selim, has launched an innovative app which uses fun brain games t

Updated on: April 01,2024

Mindset4Dementia app uses AI for next generation screening tool

by Kate Clark,University College LondonCredit: Pixabay/CC0 Public DomainA team of students and doctors, led by UCL medic Hamzah Selim, has launched an innovative app which uses fun brain games t

Updated on:April 01,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Giving common muscle relaxant via nose shows potential to treat neurodegenerative diseases

by Perelman School of Medicine at the University of PennsylvaniaPET scan of a human brain with Alzheimer's disease. Credit: public domainDelivering the medication dantrolene through the nose

Updated on: July 01,2024

Giving common muscle relaxant via nose shows potential to treat neurodegenerative diseases

by Perelman School of Medicine at the University of PennsylvaniaPET scan of a human brain with Alzheimer's disease. Credit: public domainDelivering the medication dantrolene through the nose

Updated on:July 01,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on: June 01,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on:June 01,2024

Brain stimulation may prove helpful to acute stroke patients, pilot study suggests

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainHighly targeted electrical stimulation to the brain showed promise as a new treatment for the most common type of stroke,

Updated on: February 03,2024

Brain stimulation may prove helpful to acute stroke patients, pilot study suggests

by University of California, Los AngelesCredit: Unsplash/CC0 Public DomainHighly targeted electrical stimulation to the brain showed promise as a new treatment for the most common type of stroke,

Updated on:February 03,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on: February 05,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on:February 05,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on: March 24,2024

Biogen pulls controversial Alzheimer's drug Aduhelm

Biogen said it was discontinuing Aduhelm to put more resources into Leqembi, a newer Alzheimer's medicine that was fully approved in 2023 under the traditional regulatory pathway.A controversial A

Updated on:March 24,2024