Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on: February 05,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on:February 05,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on: May 26,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on:May 26,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on: January 09,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on:January 09,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on: January 12,2024

SARS-CoV-2 virus found to migrate within neurons and infect the brain

byPasteur InstituteClinical profile of hamsters infected with SARS-CoV-2 original virus (Wuhan), the recombinant Wuhan/ΔORF7ab or the variants of concern (VoC) Gamma, Delta, and Omicron/BA.1.&nb

Updated on:January 12,2024

Seizures in Alzheimer's mouse model disrupt adult neurogenesis

by Baylor College of MedicineDr. Jeannie Chin. Credit: Baylor College of MedicineMemory impairment and mood changes are typically observed in patients with Alzheimer's disease but what distur

Updated on: April 20,2024

Seizures in Alzheimer's mouse model disrupt adult neurogenesis

by Baylor College of MedicineDr. Jeannie Chin. Credit: Baylor College of MedicineMemory impairment and mood changes are typically observed in patients with Alzheimer's disease but what distur

Updated on:April 20,2024

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on: May 20,2024

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on:May 20,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on: June 01,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on:June 01,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Understanding and Treating Parkinson's Disease: Unraveling Molecular Signals and Therapeutic Strategies

Updated on: May 17,2024

Understanding and Treating Parkinson's Disease: Unraveling Molecular Signals and Therapeutic Strategies

Updated on:May 17,2024

Shorter telomeres point to increased Alzheimer's risk

by Kim Krieger,University of ConnecticutHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShort telomeres in midlife are associated with a higher risk of develo

Updated on: May 22,2024

Shorter telomeres point to increased Alzheimer's risk

by Kim Krieger,University of ConnecticutHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShort telomeres in midlife are associated with a higher risk of develo

Updated on:May 22,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on: January 11,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on:January 11,2024