Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on: January 09,2024

Stem cell scientists develop game-changing organoid model to study human cerebellar development and disease

byKeck School of Medicine of USCCredit: Pixabay/CC0 Public DomainIn a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato has pioneered a novel human brain organoid model that

Updated on:January 09,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on: January 11,2024

Approaching and avoiding 'bad' decisions are linked with different neural communication patterns

by Ingrid Fadelli , Medical XpressOverall neural network organization for avoiding decisions (A), as opposed to approaching decisions (B). These different network organizations potentially show more c

Updated on:January 11,2024

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on: May 20,2024

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on:May 20,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on: February 05,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on:February 05,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on: April 16,2024

No cure for Alzheimer's disease in my lifetime

by Norman A. Paradis,The ConversationCredit: SAM LIN from PexelsBiogen recently announced that it was abandoning its late stage drug for Alzheimer's,aducanumab, causing investors to&nb

Updated on:April 16,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on: June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on:June 07,2024

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved

Updated on: May 26,2024

Halloween can be a scary time for people with dementia. Here's how to help

by Cara MurezWhen there are suddenly creepy decorations and lots of knocks at the door from strangers, Halloween can be frightening for someone living withdementia.It is possible to keep a loved

Updated on:May 26,2024

'Curved' walking and a depth camera: New tool detects early cognitive decline

by Florida Atlantic UniversityMahmoud Seifallahi (seated) and Behnaz Ghoraani, Ph.D., reviewing walking performance using a depth camera, which can detect and track 25 joints of body movement. Cr

Updated on: March 19,2024

'Curved' walking and a depth camera: New tool detects early cognitive decline

by Florida Atlantic UniversityMahmoud Seifallahi (seated) and Behnaz Ghoraani, Ph.D., reviewing walking performance using a depth camera, which can detect and track 25 joints of body movement. Cr

Updated on:March 19,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

How human and dog interactions affect the brain

byWileyCredit: Pixabay/CC0 Public DomainDuring social interactions, the activity of the brain's neurons becomes synchronized between the individuals involved. New researchpublished&nbs

Updated on: September 23,2024

How human and dog interactions affect the brain

byWileyCredit: Pixabay/CC0 Public DomainDuring social interactions, the activity of the brain's neurons becomes synchronized between the individuals involved. New researchpublished&nbs

Updated on:September 23,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on: July 06,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on:July 06,2024