Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on: September 23,2024

Hippocampal study unveils distinct protein machineries for calcium channel clustering and vesicle priming

by Ingrid Fadelli , Medical XpressMunc13-1 and CaV2.1 nanoclustering. a–c, Example STED images of sideview synapses (a), quantification of line profiles (b) and Pearson's colocalization coefficien

Updated on:September 23,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Where you live may be associated with more successful stroke recovery

by American Heart AssociationCredit: Pixabay/CC0 Public DomainStroke survivors living in areas with poor economic conditions were twice as likely to have a poor recovery compared to survivors liv

Updated on: March 15,2024

Where you live may be associated with more successful stroke recovery

by American Heart AssociationCredit: Pixabay/CC0 Public DomainStroke survivors living in areas with poor economic conditions were twice as likely to have a poor recovery compared to survivors liv

Updated on:March 15,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on: June 01,2024

A diet of essential amino acids could keep dementia at bay

by The National Institutes for Quantum Science and TechnologyFig. 1. Neurodegenerative processes in rTg4510 mice are accelerated by an LPD and ameliorated by Amino LP7.(A) Schematic diagram of the exp

Updated on:June 01,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on: February 24,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on:February 24,2024

How touch dampens the brain's response to painful stimuli

by Jennifer Michalowski,Massachusetts Institute of TechnologyNeurons in the thalamus (green) project to the somatosensory cortex and relay tactile information. These neurons are required for tou

Updated on: February 05,2024

How touch dampens the brain's response to painful stimuli

by Jennifer Michalowski,Massachusetts Institute of TechnologyNeurons in the thalamus (green) project to the somatosensory cortex and relay tactile information. These neurons are required for tou

Updated on:February 05,2024

Neurosurgeon explains the difference in brain aneurysms

by Deb Balzer, Mayo Clinic News NetworkCredit: CC0 Public DomainEach year, nearly half a million people worldwide die from brain aneurysms. In the U.S., an estimated 6.7 million people have an unruptu

Updated on: March 28,2024

Neurosurgeon explains the difference in brain aneurysms

by Deb Balzer, Mayo Clinic News NetworkCredit: CC0 Public DomainEach year, nearly half a million people worldwide die from brain aneurysms. In the U.S., an estimated 6.7 million people have an unruptu

Updated on:March 28,2024

Mindset4Dementia app uses AI for next generation screening tool

by Kate Clark,University College LondonCredit: Pixabay/CC0 Public DomainA team of students and doctors, led by UCL medic Hamzah Selim, has launched an innovative app which uses fun brain games t

Updated on: April 01,2024

Mindset4Dementia app uses AI for next generation screening tool

by Kate Clark,University College LondonCredit: Pixabay/CC0 Public DomainA team of students and doctors, led by UCL medic Hamzah Selim, has launched an innovative app which uses fun brain games t

Updated on:April 01,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on: February 26,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on:February 26,2024

Helping dementia carers make sense of their experiences

by Cardiff UniversityCredit: Cardiff UniversityA powerful new animation produced by Cardiff University and narrated by Sir Tony Robinson has laid bare the communication difficulties facing people

Updated on: April 25,2024

Helping dementia carers make sense of their experiences

by Cardiff UniversityCredit: Cardiff UniversityA powerful new animation produced by Cardiff University and narrated by Sir Tony Robinson has laid bare the communication difficulties facing people

Updated on:April 25,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024