Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

New study reveals how the brain orchestrates motions in partnership with sensory cues from the body

byColumbia UniversityMicroscope image of a fly brain (gray) with magenta visual neurons connecting to a motor neuron in this study (green). Credit: Stephen Huston, Zuckerman Institute; Rebecca J

Updated on: March 28,2024

New study reveals how the brain orchestrates motions in partnership with sensory cues from the body

byColumbia UniversityMicroscope image of a fly brain (gray) with magenta visual neurons connecting to a motor neuron in this study (green). Credit: Stephen Huston, Zuckerman Institute; Rebecca J

Updated on:March 28,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on: January 11,2024

Different pain types in multiple sclerosis can cause difficulty staying active

by Valerie Goodwin,University of MichiganCredit: CC0 Public DomainFor patients with multiple sclerosis, a regular exercise routine is important for managing symptoms. But due to different causes

Updated on:January 11,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on: May 20,2024

Protein aggregation: Protein assemblies relevant not only for neurodegenerative disease

by Heinrich-Heine University DuesseldorfCross section of the 3D model of an amyloid fibril against the backdrop of a cryo-electron microscopy recording. A PI3K SH3 domain is highlighted in yellow. Cre

Updated on:May 20,2024

New approach to traumatic brain injuries could revolutionise diagnosis and treatment

by Queen Mary, University of LondonFigure 1. Cerebral biopsy sample and fluorescent immunostaining. (A) An image of the cerebral biopsy obtained from a severe TBI patient and fixed in 10% formali

Updated on: February 03,2024

New approach to traumatic brain injuries could revolutionise diagnosis and treatment

by Queen Mary, University of LondonFigure 1. Cerebral biopsy sample and fluorescent immunostaining. (A) An image of the cerebral biopsy obtained from a severe TBI patient and fixed in 10% formali

Updated on:February 03,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on: February 21,2024

How does the brain make memories?

by Cedars-Sinai Medical CenterCredit: CC0 Public DomainIn a study led by Cedars-Sinai, researchers have discovered two types of brain cells that play a key role in dividing continuous human exper

Updated on:February 21,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on: March 30,2024

Molecular mechanism behind HIV-associated dementia revealed

by Will Doss,Northwestern UniversityThe interaction between APP (red) and GAG (green) in the cell. Credit: Northwestern UniversityFor the first time, scientists have identified and inhibited a m

Updated on:March 30,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on: July 06,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on:July 06,2024

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on: February 03,2024

How processing speed affects the benefits of cognitive rehabilitation for individuals with traumatic brain injury

by Kessler FoundationCredit: Pixabay/CC0 Public DomainScientists at Kessler Foundation reported results from a randomized controlled trial examining the influence of processing speed on treatment bene

Updated on:February 03,2024

How do we get more women into health care and medical leadership?

by Medical Journal of Australia (MJA)Credit: National Cancer Institute on UnsplashWomen continue to be under-represented in health care and medical leadership in Australia, with experts labeling the d

Updated on: March 19,2024

How do we get more women into health care and medical leadership?

by Medical Journal of Australia (MJA)Credit: National Cancer Institute on UnsplashWomen continue to be under-represented in health care and medical leadership in Australia, with experts labeling the d

Updated on:March 19,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on: April 25,2024

Targeting the LANDO pathway holds a potential clue to treating Alzheimer's disease

by St. Jude Children's Research HospitalBradlee Heckmann, Ph.D., of St. Jude Immunology. Credit: St. Jude Children's Research HospitalScientists at St. Jude Children's Research Hospit

Updated on:April 25,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on: March 26,2024

C/EBPβ/AEP pathway dictates both Alzheimer's disease and longevity: Study

by Chinese Academy of SciencesNeuronal C/EBPβ escalation shortens the life span of mice, leading to neural excitation. Credit: SIATCognitive decline during normal aging is exacerbated in neurodeg

Updated on:March 26,2024