FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on: May 26,2024

Sorting protein in neurons defends against neurodegenerative disease

by Temple UniversityDomenico Praticò, MD, Scott Richards North Star Foundation Chair for Alzheimer's Research, Professor in the Departments of Pharmacology and Microbiology, and Director of t

Updated on:May 26,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on: June 01,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on:June 01,2024

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on: May 20,2024

Could a Mediterranean diet and exercise reduce dementia risk?

by University of East AngliaCredit: CC0 Public DomainResearchers at the University of East Anglia (UEA) are launching a new study to see whether eating a Mediterranean-style diet and being more a

Updated on:May 20,2024

'Curved' walking and a depth camera: New tool detects early cognitive decline

by Florida Atlantic UniversityMahmoud Seifallahi (seated) and Behnaz Ghoraani, Ph.D., reviewing walking performance using a depth camera, which can detect and track 25 joints of body movement. Cr

Updated on: March 19,2024

'Curved' walking and a depth camera: New tool detects early cognitive decline

by Florida Atlantic UniversityMahmoud Seifallahi (seated) and Behnaz Ghoraani, Ph.D., reviewing walking performance using a depth camera, which can detect and track 25 joints of body movement. Cr

Updated on:March 19,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on: February 05,2024

Adult-born dentate granule cells support the activity of hippocampal cell populations

by Ingrid Fadelli , Medical XpressConfocal image of the dentate gyrus (cyan), with labelled adult-born dentate granule cells (magenta). Image credit: Katja Hartwich/Stephen McHugh/David DupretThe dent

Updated on:February 05,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on: February 24,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on:February 24,2024

What allegations of Alzheimer's research fraud mean for patients

by John Mamo,The ConversationCredit: AI-generated imageAlzheimer's disease is themost prevalentform of dementia and, with a rapidly aging global population, it is fueling unprece

Updated on: April 16,2024

What allegations of Alzheimer's research fraud mean for patients

by John Mamo,The ConversationCredit: AI-generated imageAlzheimer's disease is themost prevalentform of dementia and, with a rapidly aging global population, it is fueling unprece

Updated on:April 16,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on: June 07,2024

Dementia rates more than 20% higher among black adults than UK average

by University College LondonCrude dementia prevalence (95% CI) in those aged 65 and over, by ethnic group. Credit:Alzheimer's & Dementia(2022). DOI: 10.1002/alz.12774Dementia

Updated on:June 07,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on: May 12,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on:May 12,2024