A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Negative wealth shock linked to accelerated cognitive decline

by Elana GotkineFor older adults, negative wealth shock is associated with accelerated cognitive decline and increased risks for dementia, according to a study published online Dec. 26 inJAMA Ne

Updated on: February 24,2024

Negative wealth shock linked to accelerated cognitive decline

by Elana GotkineFor older adults, negative wealth shock is associated with accelerated cognitive decline and increased risks for dementia, according to a study published online Dec. 26 inJAMA Ne

Updated on:February 24,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on: July 06,2024

Nanoscopic motor proteins in the brain build the physical structures of memory, study finds

by Albert HiuKa Fok,The ConversationCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.113906The puzzle of memory has intrigued philosophers and intellects for a very long time. P

Updated on:July 06,2024

Leading AI chatbots show dementia-like cognitive decline in tests, raising questions about their future in medicine

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainAlmost all leading large language models or "chatbots" show signs of mild cognitive impairment in tests widely used to spot ea

Updated on: January 18,2025

Leading AI chatbots show dementia-like cognitive decline in tests, raising questions about their future in medicine

byBritish Medical JournalCredit: Pixabay/CC0 Public DomainAlmost all leading large language models or "chatbots" show signs of mild cognitive impairment in tests widely used to spot ea

Updated on:January 18,2025

Could a viral illness increase chances of developing Alzheimer's or other neurodegenerative disease?

by National Institutes of HealthCredit: Unsplash/CC0 Public DomainSome viral illnesses may increase a person's chances of later developing Alzheimer's disease or another neurodegenerative

Updated on: February 05,2024

Could a viral illness increase chances of developing Alzheimer's or other neurodegenerative disease?

by National Institutes of HealthCredit: Unsplash/CC0 Public DomainSome viral illnesses may increase a person's chances of later developing Alzheimer's disease or another neurodegenerative

Updated on:February 05,2024

Research shows new documentation tool could help optimize seizure treatments in patients with epilepsy

byCU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainNew research from the University of Colorado Anschutz Medical Campus studies a new tool that will help medical providers identify pat

Updated on: January 12,2024

Research shows new documentation tool could help optimize seizure treatments in patients with epilepsy

byCU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainNew research from the University of Colorado Anschutz Medical Campus studies a new tool that will help medical providers identify pat

Updated on:January 12,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on: February 03,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on:February 03,2024

People with increased risk of Alzheimer's have deficits in navigating

by Ruhr-Universitaet-BochumCredit: Pixabay/CC0 Public DomainAnimals and humans have the ability to follow their own position in space through self-motion cues, even in the absence of any other se

Updated on: June 07,2024

People with increased risk of Alzheimer's have deficits in navigating

by Ruhr-Universitaet-BochumCredit: Pixabay/CC0 Public DomainAnimals and humans have the ability to follow their own position in space through self-motion cues, even in the absence of any other se

Updated on:June 07,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on: July 06,2024

Researchers investigate roles of orexin in energy metabolism during sleep in humans

byUniversity of TsukubaEEG record during indirect calorimetry using a whole room metabolic chamber. Credit: University of TsukubaOrexin, named after its role in feeding regulation, is a potent e

Updated on:July 06,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Having great-grandparents, cousins with Alzheimer's linked to higher risk

by American Academy of NeurologyCredit: CC0 Public DomainHaving a parent with Alzheimer's disease has been known to raise a person's risk of developing the disease, but new research sugge

Updated on: May 05,2024

Having great-grandparents, cousins with Alzheimer's linked to higher risk

by American Academy of NeurologyCredit: CC0 Public DomainHaving a parent with Alzheimer's disease has been known to raise a person's risk of developing the disease, but new research sugge

Updated on:May 05,2024

Single dual time-point PET scan identifies dual Alzheimer's biomarkers

by Society of Nuclear MedicineWhile subject #1 (left) was judged as positive for both the neuronal injury and the amyloid load biomarker, both Alzheimer's disease biomarkers were negative in

Updated on: May 20,2024

Single dual time-point PET scan identifies dual Alzheimer's biomarkers

by Society of Nuclear MedicineWhile subject #1 (left) was judged as positive for both the neuronal injury and the amyloid load biomarker, both Alzheimer's disease biomarkers were negative in

Updated on:May 20,2024