FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on: November 28,2024

Investigating specific pathological features of cerebral cavernous malformation in children

by Katie Paradis,Children's Hospital BostonCredit: CC0 Public DomainChildren with cavernous malformations face unique treatment challenges due to factors such as the malformation's locat

Updated on:November 28,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on: April 18,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on:April 18,2024

Structure of adult brain, previously thought to be fixed, is changed by treatment

by European College of NeuropsychopharmacologyRepresentative map of the affected connections in the brain. The number of these connections increased after treatment. Credit: Jonathan ReppleScient

Updated on: February 05,2024

Structure of adult brain, previously thought to be fixed, is changed by treatment

by European College of NeuropsychopharmacologyRepresentative map of the affected connections in the brain. The number of these connections increased after treatment. Credit: Jonathan ReppleScient

Updated on:February 05,2024

'Noisy' autistic brains seem better at certain tasks. Here's why neuroaffirmative research matters

by Pratik Raul, Jeroen van Boxtel and Jovana Acevska,The ConversationCredit: Pixabay/CC0 Public DomainAutism is aneurodevelopmental differenceassociated with specific experiences and

Updated on: March 30,2024

'Noisy' autistic brains seem better at certain tasks. Here's why neuroaffirmative research matters

by Pratik Raul, Jeroen van Boxtel and Jovana Acevska,The ConversationCredit: Pixabay/CC0 Public DomainAutism is aneurodevelopmental differenceassociated with specific experiences and

Updated on:March 30,2024

Having great-grandparents, cousins with Alzheimer's linked to higher risk

by American Academy of NeurologyCredit: CC0 Public DomainHaving a parent with Alzheimer's disease has been known to raise a person's risk of developing the disease, but new research sugge

Updated on: May 05,2024

Having great-grandparents, cousins with Alzheimer's linked to higher risk

by American Academy of NeurologyCredit: CC0 Public DomainHaving a parent with Alzheimer's disease has been known to raise a person's risk of developing the disease, but new research sugge

Updated on:May 05,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Touching a nerve in the fight against chronic pain and diseases

JANUARY 11, 2024by Vittoria D'Alessio,Horizon: The EU Research & Innovation MagazineCredit: Pixabay/CC0 Public DomainThe human body's longest cranial nerve has the potential to impro

Updated on: March 13,2024

Touching a nerve in the fight against chronic pain and diseases

JANUARY 11, 2024by Vittoria D'Alessio,Horizon: The EU Research & Innovation MagazineCredit: Pixabay/CC0 Public DomainThe human body's longest cranial nerve has the potential to impro

Updated on:March 13,2024

Seizures in Alzheimer's mouse model disrupt adult neurogenesis

by Baylor College of MedicineDr. Jeannie Chin. Credit: Baylor College of MedicineMemory impairment and mood changes are typically observed in patients with Alzheimer's disease but what distur

Updated on: April 20,2024

Seizures in Alzheimer's mouse model disrupt adult neurogenesis

by Baylor College of MedicineDr. Jeannie Chin. Credit: Baylor College of MedicineMemory impairment and mood changes are typically observed in patients with Alzheimer's disease but what distur

Updated on:April 20,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on: June 18,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on:June 18,2024

What happens to your brain as you age

Updated on: August 15,2024

What happens to your brain as you age

Updated on:August 15,2024