Depression symptoms in Alzheimer's could be signs for cognitive decline

by Massachusetts General HospitalCredit: CC0 Public DomainBOSTON -Increasingly, Alzheimer's disease (AD) research has focused on the preclinical stage, when people have biological evidence of

Updated on: April 18,2024

Depression symptoms in Alzheimer's could be signs for cognitive decline

by Massachusetts General HospitalCredit: CC0 Public DomainBOSTON -Increasingly, Alzheimer's disease (AD) research has focused on the preclinical stage, when people have biological evidence of

Updated on:April 18,2024

Structure of adult brain, previously thought to be fixed, is changed by treatment

by European College of NeuropsychopharmacologyRepresentative map of the affected connections in the brain. The number of these connections increased after treatment. Credit: Jonathan ReppleScient

Updated on: February 05,2024

Structure of adult brain, previously thought to be fixed, is changed by treatment

by European College of NeuropsychopharmacologyRepresentative map of the affected connections in the brain. The number of these connections increased after treatment. Credit: Jonathan ReppleScient

Updated on:February 05,2024

New research shows that the heart has a mini-brain—its own nervous system that controls the heartbeat

byKarolinska InstitutetNeuroanatomy of the adult zebrafish intracardiac nervous system. Neuroanatomy of the adult zebrafish intracardiac nervous system. Credit:Nature Communications(

Updated on: December 18,2024

New research shows that the heart has a mini-brain—its own nervous system that controls the heartbeat

byKarolinska InstitutetNeuroanatomy of the adult zebrafish intracardiac nervous system. Neuroanatomy of the adult zebrafish intracardiac nervous system. Credit:Nature Communications(

Updated on:December 18,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on: June 01,2024

Couples and young-onset dementia: Study of coping offers hope for new interventions

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers from Massachusetts General Hospital (MGH) have used a couples-based framework to describe the experiences of individuals diag

Updated on:June 01,2024

AI helping bring vital stroke care 'virtually to the patient's bedside'

JANUARY 19, 2024by Audrey Kirby,University of KentuckyJustin Fraser, M.D., and Muhammed Fawad Ishfaq, M.D., are able to quickly review patient scans through their phones. Credit: Lily Wilder/Uni

Updated on: March 13,2024

AI helping bring vital stroke care 'virtually to the patient's bedside'

JANUARY 19, 2024by Audrey Kirby,University of KentuckyJustin Fraser, M.D., and Muhammed Fawad Ishfaq, M.D., are able to quickly review patient scans through their phones. Credit: Lily Wilder/Uni

Updated on:March 13,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on: July 01,2024

Unlocking the mystery of tau for treatment of neurodegenerative diseases

by Nagoya UniversityUnder normal physiological conditions, FUS and SFPQ interact in the nucleus of nerve cells and regulate the alternative splicing of MAPT by excising exon 10. When this functio

Updated on:July 01,2024

Seizures in Alzheimer's mouse model disrupt adult neurogenesis

by Baylor College of MedicineDr. Jeannie Chin. Credit: Baylor College of MedicineMemory impairment and mood changes are typically observed in patients with Alzheimer's disease but what distur

Updated on: April 20,2024

Seizures in Alzheimer's mouse model disrupt adult neurogenesis

by Baylor College of MedicineDr. Jeannie Chin. Credit: Baylor College of MedicineMemory impairment and mood changes are typically observed in patients with Alzheimer's disease but what distur

Updated on:April 20,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Your education and income level may affect your survival, recovery from stroke

byAmerican Academy of NeurologyCredit: CC0 Public DomainPeople with low education and income levels may have a 10% increased risk of death or being dependent on others to complete daily tasks th

Updated on: January 10,2024

Your education and income level may affect your survival, recovery from stroke

byAmerican Academy of NeurologyCredit: CC0 Public DomainPeople with low education and income levels may have a 10% increased risk of death or being dependent on others to complete daily tasks th

Updated on:January 10,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on: June 18,2024

Blood-based biomarkers for Alzheimer's disease could greatly simplify diagnosis and reduce costs

by Hôpitaux Universitaires de GenèveProportion of traditional exams that could be saved by using plasma biomarkers with 95%-sensitivity or 95%-specificity cut-offs. Values indicate the proportion of s

Updated on:June 18,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on: April 02,2024

Solanezumab does not slow cognitive decline in preclinical Alzheimer disease

by Elana GotkineFor patients with preclinical Alzheimer disease, solanezumab does not slow cognitive decline, according to a study published online July 17 in theNew England Journal of Medicine&

Updated on:April 02,2024