A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on: April 28,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on:April 28,2024

Commonly used drug for Alzheimer's disease doubles risk of hospitalization

by Canadian Medical Association JournalPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug commonly used to manage symptoms of Alzheimer disease and other dementia

Updated on: April 02,2024

Commonly used drug for Alzheimer's disease doubles risk of hospitalization

by Canadian Medical Association JournalPET scan of a human brain with Alzheimer's disease. Credit: public domainA drug commonly used to manage symptoms of Alzheimer disease and other dementia

Updated on:April 02,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on: April 18,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on:April 18,2024

Neurons in mouse piriform cortex aid in recurrent circuit development, study finds

by Ingrid Fadelli , Medical XpressEmbryonically active neurons labeled in brain-wide regions, highlighting particularly dense and broad activation in piriform cortex (also known as primary olfactory c

Updated on: October 16,2024

Neurons in mouse piriform cortex aid in recurrent circuit development, study finds

by Ingrid Fadelli , Medical XpressEmbryonically active neurons labeled in brain-wide regions, highlighting particularly dense and broad activation in piriform cortex (also known as primary olfactory c

Updated on:October 16,2024

Radiomics nomograms predict cochlear, vestibular endolymphatic hydrops in meniere disease

by Elana GotkineNovel radiomics nomograms successfully predict cochlear and vestibular endolymphatic hydrops (EH) in patients with Meniere disease, according to astudypublished online Marc

Updated on: April 06,2024

Radiomics nomograms predict cochlear, vestibular endolymphatic hydrops in meniere disease

by Elana GotkineNovel radiomics nomograms successfully predict cochlear and vestibular endolymphatic hydrops (EH) in patients with Meniere disease, according to astudypublished online Marc

Updated on:April 06,2024

Hard physical work significantly increases the risk of dementia

by University of CopenhagenCredit: Pixabay/CC0 Public DomainThe muscles and joints are not the only parts of the body to be worn down by physical work. The brain and heart suffer too. A new study

Updated on: June 01,2024

Hard physical work significantly increases the risk of dementia

by University of CopenhagenCredit: Pixabay/CC0 Public DomainThe muscles and joints are not the only parts of the body to be worn down by physical work. The brain and heart suffer too. A new study

Updated on:June 01,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on: February 24,2024

Alzheimer's drugs might get into the brain faster with new ultrasound tool, study shows

by Lauran NeergaardIn this photo provided by the WVU Rockefeller Neuroscience Institute, an Alzheimer’s patient undergoes focused ultrasound treatment with the WVU RNI team in Morgantown, W.Va., on Oc

Updated on:February 24,2024

Preliminary study: Blood treatment is safe, may help treat stiff person syndrome

by American Academy of NeurologyCredit: CC0 Public DomainStiff person syndrome spectrum disorders are rare autoimmune and neurological disorders that most often cause muscle stiffness and spasms

Updated on: February 03,2024

Preliminary study: Blood treatment is safe, may help treat stiff person syndrome

by American Academy of NeurologyCredit: CC0 Public DomainStiff person syndrome spectrum disorders are rare autoimmune and neurological disorders that most often cause muscle stiffness and spasms

Updated on:February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on: February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on:February 03,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on: February 03,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on:February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on: February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on:February 03,2024