New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on: July 08,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on:July 08,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on: April 02,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on:April 02,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on: July 25,2024

Study finds siRNA ineffective in reducing mutant huntingtin gene mRNA in nucleus

byMary Ann Liebert, IncHuntingtin. Crystallographic structure of the N-terminal region of the human Huntingtin protein with an artificially attached Maltose-Binding protein used for crystallogra

Updated on:July 25,2024

Activity is important for your brain and for the prevention of Alzheimer's, suggests neurovascular study

by University of Copenhagen"By staying active, we are able to maintain a healthy vascular system so that the blood vessels stay flexible and retain the ability to drive forward the cerebrosp

Updated on: March 02,2024

Activity is important for your brain and for the prevention of Alzheimer's, suggests neurovascular study

by University of Copenhagen"By staying active, we are able to maintain a healthy vascular system so that the blood vessels stay flexible and retain the ability to drive forward the cerebrosp

Updated on:March 02,2024

Machine learning can predict rate of memory change

by Alzheimer's Research UKIn new research published today, researchers have created a machine learning algorithm that is able to form two distinct groups of people who have early memory probl

Updated on: March 07,2024

Machine learning can predict rate of memory change

by Alzheimer's Research UKIn new research published today, researchers have created a machine learning algorithm that is able to form two distinct groups of people who have early memory probl

Updated on:March 07,2024

Mice with frequent flier miles advance the Alzheimer's cause

by University of KentuckyOlivier Thibault's lab at UK uses calcium imaging techniques to measure how neurons are affected over time. Thibault leads one of four groups in a multi-center grant

Updated on: June 01,2024

Mice with frequent flier miles advance the Alzheimer's cause

by University of KentuckyOlivier Thibault's lab at UK uses calcium imaging techniques to measure how neurons are affected over time. Thibault leads one of four groups in a multi-center grant

Updated on:June 01,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on: January 12,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on:January 12,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

Researchers identify key genes in the development of the primate brain

by Bill Hathaway,Yale UniversityRegionalization of macaque telencephalon. Single-cell transcriptomics of prenatal macaque telencephalic regions distinguished subtypes spanning development. The t

Updated on: January 12,2024

Researchers identify key genes in the development of the primate brain

by Bill Hathaway,Yale UniversityRegionalization of macaque telencephalon. Single-cell transcriptomics of prenatal macaque telencephalic regions distinguished subtypes spanning development. The t

Updated on:January 12,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on: April 22,2024

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on:April 22,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024

Research team identifies new treatment target for Alzheimer's disease

byLancaster UniversityAlzheimer's disease is the leading cause of dementia and disability in old age. Credit: Lancaster UniversityResearchers at the University of Leeds and Lancaster Univers

Updated on: March 28,2024

Research team identifies new treatment target for Alzheimer's disease

byLancaster UniversityAlzheimer's disease is the leading cause of dementia and disability in old age. Credit: Lancaster UniversityResearchers at the University of Leeds and Lancaster Univers

Updated on:March 28,2024