Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on: January 12,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on:January 12,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on: June 14,2024

ALS and frontotemporal dementia: Early diagnosis thanks to an experimental test

by International School of Advanced Studies (SISSA)The scientists developed an experimental technique able to detect the protein TDP-43 even when it is present in the body in minute quantities an

Updated on:June 14,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on: February 21,2024

The brain's drainage system in 3D

by Elisabeth Reitman,Yale UniversityCredit:Journal of Experimental MedicineMeningeal lymphatic vessels are potential targets to treat brain diseases. Laboratories at Yale and the Paris Bra

Updated on:February 21,2024

Racial differences in Alzheimer's disease unveiled

by Washington University School of MedicineCredit: CC0 Public DomainAfrican-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why becaus

Updated on: April 08,2024

Racial differences in Alzheimer's disease unveiled

by Washington University School of MedicineCredit: CC0 Public DomainAfrican-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why becaus

Updated on:April 08,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on: July 05,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on:July 05,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on: March 28,2024

When does the brain process reward and risk? Neuroscientists test a computational model

by Cynthia Eller,California Institute of TechnologyNeural activity in a region of the brain called the anterior insula could utilize a representation of RePE to then decode RiPE at a later time.

Updated on:March 28,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on: August 08,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on:August 08,2024

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on: May 22,2024

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on:May 22,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on: March 07,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on:March 07,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on: February 24,2024

Clues to preventing Alzheimer's come from patient who evaded disease, despite genetics

by Washington University School of MedicineCredit:Cell(2023). DOI: 10.1016/j.cell.2023.11.029Alzheimer's disease has plagued one large Colombian family for generations, striking d

Updated on:February 24,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on: January 12,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on:January 12,2024