Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on: February 21,2024

Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on:February 21,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk

by Mayo ClinicCredit: Mayo ClinicCan estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estro

Updated on: May 13,2024

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk

by Mayo ClinicCredit: Mayo ClinicCan estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estro

Updated on:May 13,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on: November 28,2024

How cells recycle damaged mitochondria in middle age may be critical for brain health

byUniversity of HelsinkiSnapshot of a specialized nerve cell, called an interneuron, undergoing autophagy in the hippocampus—a key brain region for memory function. Credit: Anna RappeMitochondri

Updated on:November 28,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on: January 21,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on:January 21,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on: March 19,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on:March 19,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on: April 20,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on:April 20,2024

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on: February 28,2024

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on:February 28,2024

Touching a nerve in the fight against chronic pain and diseases

JANUARY 11, 2024by Vittoria D'Alessio,Horizon: The EU Research & Innovation MagazineCredit: Pixabay/CC0 Public DomainThe human body's longest cranial nerve has the potential to impro

Updated on: March 13,2024

Touching a nerve in the fight against chronic pain and diseases

JANUARY 11, 2024by Vittoria D'Alessio,Horizon: The EU Research & Innovation MagazineCredit: Pixabay/CC0 Public DomainThe human body's longest cranial nerve has the potential to impro

Updated on:March 13,2024