How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024

Viral infections including COVID are among the important causes of dementia. One more reason to consider vaccination

by John Donne Potter,The ConversationCredit: Unsplash/CC0 Public DomainWith more of us living into old age than at any other time, dementia is increasing steadily worldwide, with major individua

Updated on: April 29,2024

Viral infections including COVID are among the important causes of dementia. One more reason to consider vaccination

by John Donne Potter,The ConversationCredit: Unsplash/CC0 Public DomainWith more of us living into old age than at any other time, dementia is increasing steadily worldwide, with major individua

Updated on:April 29,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

DNA vaccine protects against toxic proteins linked to Alzheimer's

by UT Southwestern Medical CenterUT Southwestern researchers have developed a DNA vaccine that helps the body protect against toxic proteins associated with Alzheimer's disease. These images

Updated on: March 30,2024

DNA vaccine protects against toxic proteins linked to Alzheimer's

by UT Southwestern Medical CenterUT Southwestern researchers have developed a DNA vaccine that helps the body protect against toxic proteins associated with Alzheimer's disease. These images

Updated on:March 30,2024

Could a viral illness increase chances of developing Alzheimer's or other neurodegenerative disease?

by National Institutes of HealthCredit: Unsplash/CC0 Public DomainSome viral illnesses may increase a person's chances of later developing Alzheimer's disease or another neurodegenerative

Updated on: February 05,2024

Could a viral illness increase chances of developing Alzheimer's or other neurodegenerative disease?

by National Institutes of HealthCredit: Unsplash/CC0 Public DomainSome viral illnesses may increase a person's chances of later developing Alzheimer's disease or another neurodegenerative

Updated on:February 05,2024

Touchscreens and milkshakes: Study reveals more about brain's reward systems

by Cam Buchan,University of Western OntarioThe touchscreen Autoshaping task to assess Pavlovian approach behaviors toward reward-predicting stimuli. a Layout of the Autoshaping touchscreen opera

Updated on: February 03,2024

Touchscreens and milkshakes: Study reveals more about brain's reward systems

by Cam Buchan,University of Western OntarioThe touchscreen Autoshaping task to assess Pavlovian approach behaviors toward reward-predicting stimuli. a Layout of the Autoshaping touchscreen opera

Updated on:February 03,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on: February 18,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on:February 18,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on: February 05,2024

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on:February 05,2024

Need for formal bereavement support in dementia care is largely underestimated

by University College LondonCredit: Unsplash/CC0 Public DomainThe need for grief counseling in dementia care may be substantially underestimated, according to new research led by a UCL academic.T

Updated on: May 08,2024

Need for formal bereavement support in dementia care is largely underestimated

by University College LondonCredit: Unsplash/CC0 Public DomainThe need for grief counseling in dementia care may be substantially underestimated, according to new research led by a UCL academic.T

Updated on:May 08,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024