Adults with Alzheimer's risk factors show subtle alterations in brain networks despite normal cognition

by Jason Clement,McGill UniversityPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers at McGill University and the Douglas Mental Health University Institute

Updated on: June 07,2024

Adults with Alzheimer's risk factors show subtle alterations in brain networks despite normal cognition

by Jason Clement,McGill UniversityPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers at McGill University and the Douglas Mental Health University Institute

Updated on:June 07,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on: March 02,2024

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on:March 02,2024

Single dual time-point PET scan identifies dual Alzheimer's biomarkers

by Society of Nuclear MedicineWhile subject #1 (left) was judged as positive for both the neuronal injury and the amyloid load biomarker, both Alzheimer's disease biomarkers were negative in

Updated on: May 20,2024

Single dual time-point PET scan identifies dual Alzheimer's biomarkers

by Society of Nuclear MedicineWhile subject #1 (left) was judged as positive for both the neuronal injury and the amyloid load biomarker, both Alzheimer's disease biomarkers were negative in

Updated on:May 20,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on: February 05,2024

Innovative method identifies rare brain cell types for the first time

by Katherine Fenz,Rockefeller UniversityEasySci enables high-throughput and low-cost single-cell transcriptome and chromatin accessibility profiling across the entire mammalian brain. Credit:&nb

Updated on:February 05,2024

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on: April 08,2024

Alzheimer's treatment holds promise for primary progressive aphasia patients

by Northwestern UniversityCredit: CC0 Public DomainNorthwestern Medicine scientists have discovered that an existing therapy frequently used to treat Alzheimer's disease might also work on pa

Updated on:April 08,2024

Alzheimer's meds are mostly tested in whites. That worries Black patients, caregivers

by Sydney MurphyLarry Griner resigned from his job in California and moved back to his childhood home in Baltimore nearly five years ago so he could care for his mother, Norma.She had been diagnosed w

Updated on: April 08,2024

Alzheimer's meds are mostly tested in whites. That worries Black patients, caregivers

by Sydney MurphyLarry Griner resigned from his job in California and moved back to his childhood home in Baltimore nearly five years ago so he could care for his mother, Norma.She had been diagnosed w

Updated on:April 08,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on: June 01,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on:June 01,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on: July 08,2024

New cellular mechanisms in Parkinson's disease discovered

by Melissa Rohman,Northwestern UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.05.003A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken

Updated on:July 08,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on: January 12,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on:January 12,2024

Treatment of metabolic dysfunction could be a potential therapy for Alzheimer's disease

by Yale-NUS CollegeCredit: CC0 Public DomainA team of researchers led by Yale-NUS College has found evidence that metabolic dysfunction is a primary cause of Alzheimer's disease.Alzheimer&#39

Updated on: May 20,2024

Treatment of metabolic dysfunction could be a potential therapy for Alzheimer's disease

by Yale-NUS CollegeCredit: CC0 Public DomainA team of researchers led by Yale-NUS College has found evidence that metabolic dysfunction is a primary cause of Alzheimer's disease.Alzheimer&#39

Updated on:May 20,2024

Brain changes following traumatic brain injury share similarities with Alzheimer's disease

by Jenesse Miller,University of Southern CaliforniaThe image displays a TBI-affected brain’s white matter connectivity as inferred using diffusion tensor imaging and streamline tractography. The

Updated on: May 13,2024

Brain changes following traumatic brain injury share similarities with Alzheimer's disease

by Jenesse Miller,University of Southern CaliforniaThe image displays a TBI-affected brain’s white matter connectivity as inferred using diffusion tensor imaging and streamline tractography. The

Updated on:May 13,2024