FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on: November 22,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on:November 22,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on: April 29,2024

Constipation may be a marker for dementia risk

by Amy NortonChronic constipation may not only be an indicator of gut health, but a potential warning sign of thinking declines, a preliminary study suggests.Researchers found that among more than 110

Updated on:April 29,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on: April 20,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on:April 20,2024

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk

by Mayo ClinicCredit: Mayo ClinicCan estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estro

Updated on: May 13,2024

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk

by Mayo ClinicCredit: Mayo ClinicCan estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estro

Updated on:May 13,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on: February 03,2024

How different flavors of inhibition save the day

by Irina Epstein,Max Planck SocietyCredit: Pixabay/CC0 Public DomainDuring development, lack of sensory experience elicits powerful plasticity mechanisms that alter brain circuitry. Many inhibit

Updated on:February 03,2024

Playtime, being social helps a dog's aging brain, study finds

by Dennis ThompsonAs their aging brains shrink, older dogs can suffer the same memory and thinking problems as many older humans do.But dogs are just like humans in another way—playtime and social act

Updated on: April 06,2024

Playtime, being social helps a dog's aging brain, study finds

by Dennis ThompsonAs their aging brains shrink, older dogs can suffer the same memory and thinking problems as many older humans do.But dogs are just like humans in another way—playtime and social act

Updated on:April 06,2024

Radiomics nomograms predict cochlear, vestibular endolymphatic hydrops in meniere disease

by Elana GotkineNovel radiomics nomograms successfully predict cochlear and vestibular endolymphatic hydrops (EH) in patients with Meniere disease, according to astudypublished online Marc

Updated on: April 06,2024

Radiomics nomograms predict cochlear, vestibular endolymphatic hydrops in meniere disease

by Elana GotkineNovel radiomics nomograms successfully predict cochlear and vestibular endolymphatic hydrops (EH) in patients with Meniere disease, according to astudypublished online Marc

Updated on:April 06,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on: March 02,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on:March 02,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on: April 18,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on:April 18,2024