Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on: May 22,2024 8

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on:May 22,2024 8

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024 17

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024 17

Looking at the way we walk can help predict cognitive decline

by IOS PressCredit: CC0 Public DomainThe way people walk is an indicator of how much their brains, as well as their bodies, are aging. Scientists reporting in a special supplement to theJou

Updated on: June 05,2024 6

Looking at the way we walk can help predict cognitive decline

by IOS PressCredit: CC0 Public DomainThe way people walk is an indicator of how much their brains, as well as their bodies, are aging. Scientists reporting in a special supplement to theJou

Updated on:June 05,2024 6

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024 0

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024 0

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024 17

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024 17

Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease

by American Academy of NeurologyCredit: CC0 Public DomainThe drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study p

Updated on: June 01,2024 3

Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease

by American Academy of NeurologyCredit: CC0 Public DomainThe drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study p

Updated on:June 01,2024 3

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on: April 29,2024 14

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on:April 29,2024 14

Mapping the human brain's default mode network: Anatomical study suggests it has widespread influence

Updated on: March 02,2025 0

Mapping the human brain's default mode network: Anatomical study suggests it has widespread influence

Updated on:March 02,2025 0

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on: February 21,2024 14

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on:February 21,2024 14

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on: June 11,2024 4

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on:June 11,2024 4

Driving with dementia—New guidance for doctors

by Newcastle UniversityNew guidelines have been published to help doctors and health care professionals assess and manage when people living with dementia should stop driving. Credit: Newcastle U

Updated on: May 09,2024 3

Driving with dementia—New guidance for doctors

by Newcastle UniversityNew guidelines have been published to help doctors and health care professionals assess and manage when people living with dementia should stop driving. Credit: Newcastle U

Updated on:May 09,2024 3

Why some types of music make people want to dance more than others

by Bob Yirka , Medical XpressTwelve 8-s melodies with a 2-Hz beat were created. For each melody, three variants were designed to vary the level of rhythmic predictability (degree of syncopation) while

Updated on: March 30,2024 10

Why some types of music make people want to dance more than others

by Bob Yirka , Medical XpressTwelve 8-s melodies with a 2-Hz beat were created. For each melody, three variants were designed to vary the level of rhythmic predictability (degree of syncopation) while

Updated on:March 30,2024 10