Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on: May 22,2024 8

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on:May 22,2024 8

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024 17

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024 17

How aggression-promoting brain peptide works in fruit flies

by Salk InstituteA fruit fly brain showing male-specific tachykininergic neurons (magenta), which make the neuropeptide tachykinin, and neurons that express TkR86C (green), which receive tachykin

Updated on: February 18,2024 18

How aggression-promoting brain peptide works in fruit flies

by Salk InstituteA fruit fly brain showing male-specific tachykininergic neurons (magenta), which make the neuropeptide tachykinin, and neurons that express TkR86C (green), which receive tachykin

Updated on:February 18,2024 18

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on: February 21,2024 14

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on:February 21,2024 14

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on: April 06,2024 0

Altered brain morphology and functional connectivity in postmenopausal women

by Impact Journals LLCBetween-group comparison map (premenopausal women vs. postmenopausal women) of the left mOFC functional connectivity. Credit:Aging(2024). DOI: 10.18632/aging.205662A

Updated on:April 06,2024 0

Make this Halloween a safe one for people with dementia

by Cara MurezHalloween is often frightening for loved ones who have dementia, but there are ways to keep it safe and not scary."Halloween can be very challenging and stressful for someone with de

Updated on: February 24,2024 13

Make this Halloween a safe one for people with dementia

by Cara MurezHalloween is often frightening for loved ones who have dementia, but there are ways to keep it safe and not scary."Halloween can be very challenging and stressful for someone with de

Updated on:February 24,2024 13

Looking at the way we walk can help predict cognitive decline

by IOS PressCredit: CC0 Public DomainThe way people walk is an indicator of how much their brains, as well as their bodies, are aging. Scientists reporting in a special supplement to theJou

Updated on: June 05,2024 6

Looking at the way we walk can help predict cognitive decline

by IOS PressCredit: CC0 Public DomainThe way people walk is an indicator of how much their brains, as well as their bodies, are aging. Scientists reporting in a special supplement to theJou

Updated on:June 05,2024 6

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024 0

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024 0

Cholesterol may be key to new therapies for Alzheimer's disease, diabetes

by University of Arizona Health SciencesCredit: Unsplash/CC0 Public DomainA University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2

Updated on: May 20,2024 4

Cholesterol may be key to new therapies for Alzheimer's disease, diabetes

by University of Arizona Health SciencesCredit: Unsplash/CC0 Public DomainA University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2

Updated on:May 20,2024 4

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on: April 29,2024 14

Risk of overactive bladder associated with medications for dementia

by University of HoustonCredit: Unsplash/CC0 Public DomainA study from the University of Houston College of Pharmacy, published in theJournal of the American Geriatrics Society, has evaluat

Updated on:April 29,2024 14

How the brain's immune system worsens epilepsy

by Richard C. Lewis,University of IowaUniversity of Iowa biologists have definitively linked the brain's immune system to epilepsy. The caption shows the sequence of events that triggers wor

Updated on: February 21,2024 15

How the brain's immune system worsens epilepsy

by Richard C. Lewis,University of IowaUniversity of Iowa biologists have definitively linked the brain's immune system to epilepsy. The caption shows the sequence of events that triggers wor

Updated on:February 21,2024 15

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on: June 11,2024 4

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on:June 11,2024 4