Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on: May 22,2024

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on:May 22,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on: February 03,2024

Different anxiety-related behaviors are mediated by different neural circuits and molecular mechanisms

by Zhejiang UniversityDRNvGluT3∩5-HT→BAPyrand DRNvGluT3∩5-HT→BAPVpathways differentially regulate anxiety-related behaviors. Credit: Zhejiang UniversityAnxiety is a common negative emotion

Updated on:February 03,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on: February 03,2024

Severity of PTSD symptoms linked to decreased activity in hippocampus

by Society for NeuroscienceFear-potentiated startle interacts with hippocampal threat reactivity in predicting PTSD at two-weeks. Credit: Tanriverdi et al.,JNeurosci2022After a trauma

Updated on:February 03,2024

Touchscreens and milkshakes: Study reveals more about brain's reward systems

by Cam Buchan,University of Western OntarioThe touchscreen Autoshaping task to assess Pavlovian approach behaviors toward reward-predicting stimuli. a Layout of the Autoshaping touchscreen opera

Updated on: February 03,2024

Touchscreens and milkshakes: Study reveals more about brain's reward systems

by Cam Buchan,University of Western OntarioThe touchscreen Autoshaping task to assess Pavlovian approach behaviors toward reward-predicting stimuli. a Layout of the Autoshaping touchscreen opera

Updated on:February 03,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on: February 18,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on:February 18,2024

Are the olfactory responses of patients in a coma or vegetative state signs of consciousness?

by Ingrid Fadelli , Medical XpressBehavioral results and global connectivity among HCs, ORES, and N-ORES. (A) The proportion of olfactory response among MCS and VS/UWS patients. A relationship was obs

Updated on: February 03,2024

Are the olfactory responses of patients in a coma or vegetative state signs of consciousness?

by Ingrid Fadelli , Medical XpressBehavioral results and global connectivity among HCs, ORES, and N-ORES. (A) The proportion of olfactory response among MCS and VS/UWS patients. A relationship was obs

Updated on:February 03,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on: March 02,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on:March 02,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on: April 20,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on:April 20,2024

Neuroscientists use brain activity patterns to reveal thoughts of brain-injured patients

by Jeff Renaud,University of Western OntarioAdrian Owen (left) and Karnig Kazazian combine different neuroimaging methods to assess patients at the bedside in the first few days after their brai

Updated on: July 31,2024

Neuroscientists use brain activity patterns to reveal thoughts of brain-injured patients

by Jeff Renaud,University of Western OntarioAdrian Owen (left) and Karnig Kazazian combine different neuroimaging methods to assess patients at the bedside in the first few days after their brai

Updated on:July 31,2024

Computer avatars play a part in dementia detection

by Osaka UniversityFigure 1. Human-Avatar Dialogue System. Figure 1. Human-Avatar Dialogue System: (a)Introduction “What’s your name?”(b) Gaze measurement(c) Reading test(d) Fixed question “What’

Updated on: May 22,2024

Computer avatars play a part in dementia detection

by Osaka UniversityFigure 1. Human-Avatar Dialogue System. Figure 1. Human-Avatar Dialogue System: (a)Introduction “What’s your name?”(b) Gaze measurement(c) Reading test(d) Fixed question “What’

Updated on:May 22,2024