A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on: April 28,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on:April 28,2024

Clustering method can better describe the pathological process in patients with traumatic brain injury

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainMonitoring brain injury biomarkers and glucose variation in patients who have suffered an acute cranial injury during the entire first wee

Updated on: January 10,2024

Clustering method can better describe the pathological process in patients with traumatic brain injury

byKarolinska InstitutetCredit: Pixabay/CC0 Public DomainMonitoring brain injury biomarkers and glucose variation in patients who have suffered an acute cranial injury during the entire first wee

Updated on:January 10,2024

Examining molecular biomarkers to diagnose vascular cognitive impairment and dementia

by University of New South WalesPathophysiological processes of vascular cognitive impairment and dementia, their interactions and potential biomarkers. Credit:Nature Reviews Neurology&nbsp

Updated on: June 20,2024

Examining molecular biomarkers to diagnose vascular cognitive impairment and dementia

by University of New South WalesPathophysiological processes of vascular cognitive impairment and dementia, their interactions and potential biomarkers. Credit:Nature Reviews Neurology&nbsp

Updated on:June 20,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on: February 27,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on:February 27,2024

Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on: February 21,2024

Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on:February 21,2024

Coronary heart disease before age 45 may increase risk of dementia later in life

by American Heart AssociationCredit: CC0 Public DomainAdults diagnosed with coronary heart disease, especially before the age of 45, may be at increased risk of developing dementia, Alzheimer&#39

Updated on: February 24,2024

Coronary heart disease before age 45 may increase risk of dementia later in life

by American Heart AssociationCredit: CC0 Public DomainAdults diagnosed with coronary heart disease, especially before the age of 45, may be at increased risk of developing dementia, Alzheimer&#39

Updated on:February 24,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Power of light and oxygen clears Alzheimer's disease protein in live mice

by University of TokyoCredit: Unsplash/CC0 Public DomainA small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the b

Updated on: June 05,2024

Power of light and oxygen clears Alzheimer's disease protein in live mice

by University of TokyoCredit: Unsplash/CC0 Public DomainA small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the b

Updated on:June 05,2024

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk

by Mayo ClinicCredit: Mayo ClinicCan estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estro

Updated on: May 13,2024

Estrogen patch in newly postmenopausal women may reduce Alzheimer's risk

by Mayo ClinicCredit: Mayo ClinicCan estrogen preserve brain function and decrease the risk of Alzheimer's disease when given early in menopause? Newly postmenopausal women who received estro

Updated on:May 13,2024

Researchers find new origin of deep brain waves

byUniversity of California, IrvineSpindle frequencies embedded in the spike train. (A) Raw data of single axon from CA3 feedback to DG (F12-G12) channels, array ECDGCA3CA1 19908 160518 160610 d2

Updated on: April 28,2024

Researchers find new origin of deep brain waves

byUniversity of California, IrvineSpindle frequencies embedded in the spike train. (A) Raw data of single axon from CA3 feedback to DG (F12-G12) channels, array ECDGCA3CA1 19908 160518 160610 d2

Updated on:April 28,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on: April 28,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on:April 28,2024