FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on: November 22,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on:November 22,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on: February 26,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on:February 26,2024

ANKRD55: A new gene involved in Multiple Sclerosis is discovered

by University of the Basque CountryThis image shows intracellular localization of ANKRD55 in Jurkat, SH-SY5Y and PMA-treated U937 cells. Credit: Koen VandenbroeckMultiple Sclerosis (MS) is a neur

Updated on: March 26,2024

ANKRD55: A new gene involved in Multiple Sclerosis is discovered

by University of the Basque CountryThis image shows intracellular localization of ANKRD55 in Jurkat, SH-SY5Y and PMA-treated U937 cells. Credit: Koen VandenbroeckMultiple Sclerosis (MS) is a neur

Updated on:March 26,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on: July 01,2024

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on:July 01,2024

Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on: July 08,2024

Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on:July 08,2024

Could a viral illness increase chances of developing Alzheimer's or other neurodegenerative disease?

by National Institutes of HealthCredit: Unsplash/CC0 Public DomainSome viral illnesses may increase a person's chances of later developing Alzheimer's disease or another neurodegenerative

Updated on: February 05,2024

Could a viral illness increase chances of developing Alzheimer's or other neurodegenerative disease?

by National Institutes of HealthCredit: Unsplash/CC0 Public DomainSome viral illnesses may increase a person's chances of later developing Alzheimer's disease or another neurodegenerative

Updated on:February 05,2024

Touchscreens and milkshakes: Study reveals more about brain's reward systems

by Cam Buchan,University of Western OntarioThe touchscreen Autoshaping task to assess Pavlovian approach behaviors toward reward-predicting stimuli. a Layout of the Autoshaping touchscreen opera

Updated on: February 03,2024

Touchscreens and milkshakes: Study reveals more about brain's reward systems

by Cam Buchan,University of Western OntarioThe touchscreen Autoshaping task to assess Pavlovian approach behaviors toward reward-predicting stimuli. a Layout of the Autoshaping touchscreen opera

Updated on:February 03,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on: April 20,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on:April 20,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on: February 18,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on:February 18,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on: April 28,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on:April 28,2024