Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on: November 22,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on:November 22,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Power of light and oxygen clears Alzheimer's disease protein in live mice

by University of TokyoCredit: Unsplash/CC0 Public DomainA small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the b

Updated on: June 05,2024

Power of light and oxygen clears Alzheimer's disease protein in live mice

by University of TokyoCredit: Unsplash/CC0 Public DomainA small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the b

Updated on:June 05,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on: April 18,2024

Alzheimer's breakthrough: Two short strings of amino acids could pave the way to new treatments

by Ryan O'byrne,University of AlbertaU of A neurologist Jack Jhamandas led a team that found a new treatment significantly improved memory in mice with Alzheimer's disease. The researche

Updated on:April 18,2024

Eating less processed red meat could cut your odds for dementia

by Ernie MundellSkip the bacon and those holiday hot dogs: A new study finds eating processed red meats raises your odds for dementia.Overall, just two servings per week of processed red meat was link

Updated on: August 31,2024

Eating less processed red meat could cut your odds for dementia

by Ernie MundellSkip the bacon and those holiday hot dogs: A new study finds eating processed red meats raises your odds for dementia.Overall, just two servings per week of processed red meat was link

Updated on:August 31,2024

Restoring brain function in mice with symptoms of Alzheimer's disease

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainA study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alz

Updated on: June 11,2024

Restoring brain function in mice with symptoms of Alzheimer's disease

by Johns Hopkins University School of MedicineCredit: CC0 Public DomainA study in mice shows that selectively removing cells that are no longer dividing from the brains of mice with a form of Alz

Updated on:June 11,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on: May 12,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on:May 12,2024

'Noisy' autistic brains seem better at certain tasks. Here's why neuroaffirmative research matters

by Pratik Raul, Jeroen van Boxtel and Jovana Acevska,The ConversationCredit: Pixabay/CC0 Public DomainAutism is aneurodevelopmental differenceassociated with specific experiences and

Updated on: March 30,2024

'Noisy' autistic brains seem better at certain tasks. Here's why neuroaffirmative research matters

by Pratik Raul, Jeroen van Boxtel and Jovana Acevska,The ConversationCredit: Pixabay/CC0 Public DomainAutism is aneurodevelopmental differenceassociated with specific experiences and

Updated on:March 30,2024

Neuromuscular training cuts onset of chemo-induced peripheral neuropathy

by Elana GotkineNeuromuscular training reduces the onset of chemotherapy-induced peripheral neuropathy (CIPN), according to a study published online July 1 inJAMA Internal Medicine.Fiona Streckm

Updated on: July 31,2024

Neuromuscular training cuts onset of chemo-induced peripheral neuropathy

by Elana GotkineNeuromuscular training reduces the onset of chemotherapy-induced peripheral neuropathy (CIPN), according to a study published online July 1 inJAMA Internal Medicine.Fiona Streckm

Updated on:July 31,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on: April 28,2024

A flexible microdisplay that can monitor brain activity in real-time during brain surgery

by University of California - San DiegoEach LED in the device mirrors the activity of a few thousand neurons. Credit: University of California San DiegoResearchers have created a thin film that c

Updated on:April 28,2024