How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on: March 19,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on:March 19,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024

Understanding the how and why of preterm brain injury

by Rob Clancy,Hudson Institute of Medical ResearchRepresentative images of NeuN- and MAP2-positive cells in the cortical gray matter (cortex; Layer V) and caudate. Scale bar represents 50μ

Updated on: September 23,2024

Understanding the how and why of preterm brain injury

by Rob Clancy,Hudson Institute of Medical ResearchRepresentative images of NeuN- and MAP2-positive cells in the cortical gray matter (cortex; Layer V) and caudate. Scale bar represents 50μ

Updated on:September 23,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on: February 18,2024

Oxytocin spreads cooperation in social networks

by Society for NeuroscienceSchematic of the artificial social networks in the cooperation games. Credit: Li et al.,JNeurosci2022Administering oxytocin to the central members of a soci

Updated on:February 18,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on: June 17,2024

Risk factors for Parkinson's disease: Study proves the protective function of the RIT2 gene

by Eurac ResearchIn vivo aSyn overexpression increases endogenous LRRK2 activity, which is prevented by Rit2 co-expression.aPLA analysis of AAV-GFP, AAV-A53T-aSyn and AAV-A53T-aSyn + AAV-R

Updated on:June 17,2024

Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on: February 21,2024

Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on:February 21,2024

Untangling the threads of early onset dementia

by Lynda De Widt, Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainChanges in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementi

Updated on: April 06,2024

Untangling the threads of early onset dementia

by Lynda De Widt, Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainChanges in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementi

Updated on:April 06,2024

Could sudden infant death syndrome be caused by unrecognized brain infections?

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainSome infants who pass away from sudden infant death syndrome (SIDS) are known to have had acute minor infections.

Updated on: March 30,2024

Could sudden infant death syndrome be caused by unrecognized brain infections?

by Nancy Fliesler,Children's Hospital BostonCredit: Pixabay/CC0 Public DomainSome infants who pass away from sudden infant death syndrome (SIDS) are known to have had acute minor infections.

Updated on:March 30,2024

Study identifies new biomarkers of Alzheimer's disease

by Ingrid Fadelli , Medical XpressStudy overview. Credit:Nature Human Behaviour(2024). DOI: 10.1038/s41562-024-01924-6Recent advances in the study of proteomes (i.e., the entire range of p

Updated on: July 31,2024

Study identifies new biomarkers of Alzheimer's disease

by Ingrid Fadelli , Medical XpressStudy overview. Credit:Nature Human Behaviour(2024). DOI: 10.1038/s41562-024-01924-6Recent advances in the study of proteomes (i.e., the entire range of p

Updated on:July 31,2024

AI helping bring vital stroke care 'virtually to the patient's bedside'

JANUARY 19, 2024by Audrey Kirby,University of KentuckyJustin Fraser, M.D., and Muhammed Fawad Ishfaq, M.D., are able to quickly review patient scans through their phones. Credit: Lily Wilder/Uni

Updated on: March 13,2024

AI helping bring vital stroke care 'virtually to the patient's bedside'

JANUARY 19, 2024by Audrey Kirby,University of KentuckyJustin Fraser, M.D., and Muhammed Fawad Ishfaq, M.D., are able to quickly review patient scans through their phones. Credit: Lily Wilder/Uni

Updated on:March 13,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on: February 21,2024

Specific brain responses to traumatic stress linked to PTSD risk

by University of North Carolina Health CareCredit: CC0 Public DomainResults from the largest prospective study of its kind indicate that in the initial days and weeks after experiencing trauma, i

Updated on:February 21,2024