Protein shapes matter in Alzheimer's research

by Allison Mills,Michigan Technological UniversityCellular toxicity, which is higher in amyloid amorphous aggregates, shows that small changes in protein folding chemistry can cause differences

Updated on: April 16,2024 12

Protein shapes matter in Alzheimer's research

by Allison Mills,Michigan Technological UniversityCellular toxicity, which is higher in amyloid amorphous aggregates, shows that small changes in protein folding chemistry can cause differences

Updated on:April 16,2024 12

Reorganization of prefrontal cortex circuitry during adolescence enables cognitive maturation of mice

by Ingrid Fadelli , Medical XpressThe artistic image shows that the structural and functional development of neuronal circuits in the prefrontal cortex is supported by microglia mediated refinement of

Updated on: March 28,2024 0

Reorganization of prefrontal cortex circuitry during adolescence enables cognitive maturation of mice

by Ingrid Fadelli , Medical XpressThe artistic image shows that the structural and functional development of neuronal circuits in the prefrontal cortex is supported by microglia mediated refinement of

Updated on:March 28,2024 0

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on: April 23,2024 0

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on:April 23,2024 0

Physicians debate best screening tools and practices for patients with potential dementia and cognitive impairment

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainIn a new Annals 'Beyond the Guideline's feature, two experts review the available evidence about cognitive impairment to

Updated on: March 02,2024 11

Physicians debate best screening tools and practices for patients with potential dementia and cognitive impairment

by American College of PhysiciansCredit: Pixabay/CC0 Public DomainIn a new Annals 'Beyond the Guideline's feature, two experts review the available evidence about cognitive impairment to

Updated on:March 02,2024 11

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on: March 02,2024 11

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on:March 02,2024 11

Spinal fluid of people with Alzheimer's risk gene signals inflammation

by Duke University Medical CenterCredit: Pixabay/CC0 Public DomainPeople who have a gene variant associated with an increased risk of developing Alzheimer's disease also tend to have changes

Updated on: April 20,2024 12

Spinal fluid of people with Alzheimer's risk gene signals inflammation

by Duke University Medical CenterCredit: Pixabay/CC0 Public DomainPeople who have a gene variant associated with an increased risk of developing Alzheimer's disease also tend to have changes

Updated on:April 20,2024 12

A potential agent for treating preeclampsia

by Max Delbrück Center for Molecular MedicineThis image helps researchers analyze, among other things, the spiral arteries in order to gain insights into fetal nutrition. Credit: Nadine Haase, MD

Updated on: May 11,2024 6

A potential agent for treating preeclampsia

by Max Delbrück Center for Molecular MedicineThis image helps researchers analyze, among other things, the spiral arteries in order to gain insights into fetal nutrition. Credit: Nadine Haase, MD

Updated on:May 11,2024 6

Boosting neuron formation restores memory in mice with Alzheimer's disease

by Rockefeller University PressThe new study shows that boosting neurogenesis increases the number of newly formed neurons involved in storing and retrieving memories (arrows) in the hippocampus

Updated on: February 18,2024 5

Boosting neuron formation restores memory in mice with Alzheimer's disease

by Rockefeller University PressThe new study shows that boosting neurogenesis increases the number of newly formed neurons involved in storing and retrieving memories (arrows) in the hippocampus

Updated on:February 18,2024 5

Pathway deep in the brain makes it resilient after injury

by Sarah Williams,Gladstone InstitutesA new study led by Gladstone researchers suggests that targeting a protein in the thalamus could prevent the long-term damage that follows traumatic brain i

Updated on: February 21,2024 16

Pathway deep in the brain makes it resilient after injury

by Sarah Williams,Gladstone InstitutesA new study led by Gladstone researchers suggests that targeting a protein in the thalamus could prevent the long-term damage that follows traumatic brain i

Updated on:February 21,2024 16

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on: June 18,2024 6

'Viral relicts' in the genome could fuel neurodegeneration

by Marcus Neitzert, Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)Different HERV glycoproteins increase intercellular protein aggregate spreading.aExperimental workflow.

Updated on:June 18,2024 6

Alzheimer's leads to changes in the small blood vessels in the brain

by University of OsloEarlier research has shown that several of the same risk factors behind the development of cardiovascular disease also can lead to Alzheimer’s. Pictured left to right: Shreya

Updated on: April 25,2024 14

Alzheimer's leads to changes in the small blood vessels in the brain

by University of OsloEarlier research has shown that several of the same risk factors behind the development of cardiovascular disease also can lead to Alzheimer’s. Pictured left to right: Shreya

Updated on:April 25,2024 14

Magnetic microcoils unlock targeted single-neuron therapies for neurodegenerative disorders

byAmerican Institute of PhysicsA microscopic view of the MagPatch array showing six of the eight microcoils used for nerve stimulation. Credit: Saha et al.Neural stimulation is a medical techniq

Updated on: April 28,2024 0

Magnetic microcoils unlock targeted single-neuron therapies for neurodegenerative disorders

byAmerican Institute of PhysicsA microscopic view of the MagPatch array showing six of the eight microcoils used for nerve stimulation. Credit: Saha et al.Neural stimulation is a medical techniq

Updated on:April 28,2024 0