A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on: January 12,2024

World's first collection of brain metastasis living samples will help treat each patient with the most effective therapy

byThe Spanish National Cancer Research CentreSample prepared, classified and conserved at the CNIO Biobank. Credit: Laura M. Lombardía / CNIOAt 18 Spanish hospitals, when a patient with brain me

Updated on:January 12,2024

A telltale protein spreads throughout the brain in distinct patterns based on patients' Alzheimer's phenotype

by Delthia Ricks , Medical XpressIdentification of specific anatomical tracts using tau-PET seeds from each clinical group. Credit: J. Therriault, et al.,Science Translational Medicine(202

Updated on: June 05,2024

A telltale protein spreads throughout the brain in distinct patterns based on patients' Alzheimer's phenotype

by Delthia Ricks , Medical XpressIdentification of specific anatomical tracts using tau-PET seeds from each clinical group. Credit: J. Therriault, et al.,Science Translational Medicine(202

Updated on:June 05,2024

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on: February 05,2024

Gut bacteria changes could signal onset of rare genetic disease

by Georgia Gowing,Macquarie UniversityGraphical abstract. Credit:Neurobiology of Disease(2023). DOI: 10.1016/j.nbd.2023.106051New research may have uncovered a relationship between c

Updated on:February 05,2024

Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on: February 21,2024

Growth charts for the brain help to understand mental illness

by Radboud UniversityResearchers have developed growth charts for the brain as reference models for brain develpment and aging. Credit: Andre MarquandResearchers from Radboudumc have developed a

Updated on:February 21,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on: April 16,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on:April 16,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on: January 21,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on:January 21,2024

Thinking 'out-of-the-box' may build a better brain and prevent dementia

by Florida Atlantic UniversityFAU Neuroscientist James Galvin, M.D., uses the functional range of motion board to test a patient's manual dexterity as part of the Dementia Prevention Initiati

Updated on: March 13,2024

Thinking 'out-of-the-box' may build a better brain and prevent dementia

by Florida Atlantic UniversityFAU Neuroscientist James Galvin, M.D., uses the functional range of motion board to test a patient's manual dexterity as part of the Dementia Prevention Initiati

Updated on:March 13,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on: February 03,2024

Beyond neurons: How cells called astrocytes contribute to brain disorders

by Salk InstituteSalk researchers studied the molecules produced by astrocytes, like those pictured, to understand how the cells play a role in neurodevelopmental disorders. Credit: Salk Institut

Updated on:February 03,2024

Research shows new documentation tool could help optimize seizure treatments in patients with epilepsy

byCU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainNew research from the University of Colorado Anschutz Medical Campus studies a new tool that will help medical providers identify pat

Updated on: January 12,2024

Research shows new documentation tool could help optimize seizure treatments in patients with epilepsy

byCU Anschutz Medical CampusCredit: Pixabay/CC0 Public DomainNew research from the University of Colorado Anschutz Medical Campus studies a new tool that will help medical providers identify pat

Updated on:January 12,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on: April 02,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on:April 02,2024