Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on: January 12,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on:January 12,2024

Are the olfactory responses of patients in a coma or vegetative state signs of consciousness?

by Ingrid Fadelli , Medical XpressBehavioral results and global connectivity among HCs, ORES, and N-ORES. (A) The proportion of olfactory response among MCS and VS/UWS patients. A relationship was obs

Updated on: February 03,2024

Are the olfactory responses of patients in a coma or vegetative state signs of consciousness?

by Ingrid Fadelli , Medical XpressBehavioral results and global connectivity among HCs, ORES, and N-ORES. (A) The proportion of olfactory response among MCS and VS/UWS patients. A relationship was obs

Updated on:February 03,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on: January 21,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on:January 21,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on: May 06,2024

Dementia metaphors help describe the condition, but can also perpetuate stigma and hinder treatment

by Jasmine Mah and Kaitlin Sibbald,The ConversationCredit: AI-generated imageHalf a million Canadians are living with dementiaandone in five Canadians has cared for someone with deme

Updated on:May 06,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on: March 02,2024

Unlocking how the new Alzheimer's drug lecanemab works

by Rockefeller UniversityA false-color SEM image of a fibrin blood clot before and after the buildup of amyloid-beta proteins called protofibrils. Credit: Pradeep Singh, PhD; Images collected at

Updated on:March 02,2024

Power of light and oxygen clears Alzheimer's disease protein in live mice

by University of TokyoCredit: Unsplash/CC0 Public DomainA small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the b

Updated on: June 05,2024

Power of light and oxygen clears Alzheimer's disease protein in live mice

by University of TokyoCredit: Unsplash/CC0 Public DomainA small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the b

Updated on:June 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on: April 02,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on:April 02,2024

Playtime, being social helps a dog's aging brain, study finds

by Dennis ThompsonAs their aging brains shrink, older dogs can suffer the same memory and thinking problems as many older humans do.But dogs are just like humans in another way—playtime and social act

Updated on: April 06,2024

Playtime, being social helps a dog's aging brain, study finds

by Dennis ThompsonAs their aging brains shrink, older dogs can suffer the same memory and thinking problems as many older humans do.But dogs are just like humans in another way—playtime and social act

Updated on:April 06,2024

Hard physical work significantly increases the risk of dementia

by University of CopenhagenCredit: Pixabay/CC0 Public DomainThe muscles and joints are not the only parts of the body to be worn down by physical work. The brain and heart suffer too. A new study

Updated on: June 01,2024

Hard physical work significantly increases the risk of dementia

by University of CopenhagenCredit: Pixabay/CC0 Public DomainThe muscles and joints are not the only parts of the body to be worn down by physical work. The brain and heart suffer too. A new study

Updated on:June 01,2024

Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows

by Nagoya City UniversityCollective time-lapse images of a migrating neuron (bottom) and an elongating axon (top) from super-resolution microscopy. Growth cones at the tips of the neurons are ext

Updated on: March 19,2024

Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows

by Nagoya City UniversityCollective time-lapse images of a migrating neuron (bottom) and an elongating axon (top) from super-resolution microscopy. Growth cones at the tips of the neurons are ext

Updated on:March 19,2024