Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

Traumatic brain injury may raise veterans' long-term stroke risk

by Michael Merschel, American Heart Association NewsMilitary veterans who had a traumatic brain injury may have an increased long-term risk of stroke, new research suggests.The study, which used data

Updated on: February 03,2024

Traumatic brain injury may raise veterans' long-term stroke risk

by Michael Merschel, American Heart Association NewsMilitary veterans who had a traumatic brain injury may have an increased long-term risk of stroke, new research suggests.The study, which used data

Updated on:February 03,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on: March 19,2024

How ApoE4 endangers the brain

by Max Delbrück Center for Molecular MedicineCredit: CC0 Public DomainApolipoprotein E (ApoE) is kind of like a delivery service for the human brain. It supplies neurons with important nutrients,

Updated on:March 19,2024

Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on: June 14,2024

Genetic changes differed, increased in people with Alzheimer's disease

by Brigham and Women's HospitalCredit: Public DomainInside brain cells, errors in DNA can accumulate as we age. But in patients with Alzheimer's disease, these errors—known as somatic mut

Updated on:June 14,2024

Molecular pathology of suicide: A postmortem study

byUniversity of AmsterdamCredit: Pixabay/CC0 Public DomainWhat changes in the brains of people who commit or think about committing suicide? Ph.D. candidate Lin Zhang investigated at a molecular

Updated on: January 12,2024

Molecular pathology of suicide: A postmortem study

byUniversity of AmsterdamCredit: Pixabay/CC0 Public DomainWhat changes in the brains of people who commit or think about committing suicide? Ph.D. candidate Lin Zhang investigated at a molecular

Updated on:January 12,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on: April 02,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on:April 02,2024

What allegations of Alzheimer's research fraud mean for patients

by John Mamo,The ConversationCredit: AI-generated imageAlzheimer's disease is themost prevalentform of dementia and, with a rapidly aging global population, it is fueling unprece

Updated on: April 16,2024

What allegations of Alzheimer's research fraud mean for patients

by John Mamo,The ConversationCredit: AI-generated imageAlzheimer's disease is themost prevalentform of dementia and, with a rapidly aging global population, it is fueling unprece

Updated on:April 16,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on: March 02,2024

New study discovers how neurons die in Alzheimer's disease

by Medical Research CouncilNeurons immunoreactive to AT8, PHF1 or MC1 are segmented in Imaris software and rendered to reveal intracellular X34 staining (β-sheet fibrillary structures), an indica

Updated on:March 02,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on: March 07,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on:March 07,2024

Neural activity study shows the brain processes direct speech and its echo separately

byPublic Library of ScienceSpeech processing in an echoic environment. Credit: Jiaxin Gao (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Echoes can make speech harder to understand, and tuning

Updated on: March 13,2024

Neural activity study shows the brain processes direct speech and its echo separately

byPublic Library of ScienceSpeech processing in an echoic environment. Credit: Jiaxin Gao (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Echoes can make speech harder to understand, and tuning

Updated on:March 13,2024

Sounding the alarm on a future Alzheimer's disease epidemic

by Carla Denly,University of California, Los AngelesWe're living longer. The number of U.S. adults 65 and older—roughly 40 million as of the 2010 census—is expected to nearly double to 71 mi

Updated on: February 27,2024

Sounding the alarm on a future Alzheimer's disease epidemic

by Carla Denly,University of California, Los AngelesWe're living longer. The number of U.S. adults 65 and older—roughly 40 million as of the 2010 census—is expected to nearly double to 71 mi

Updated on:February 27,2024

Creating a biomimetic algorithm to find epileptogenic areas of the brain

by National Research University Higher School of EconomicsInterictal spike. a) Typical waveform. b) An example of color-coded activity distribution over sensors at time t=0, corresponding to the peak.

Updated on: February 03,2024

Creating a biomimetic algorithm to find epileptogenic areas of the brain

by National Research University Higher School of EconomicsInterictal spike. a) Typical waveform. b) An example of color-coded activity distribution over sensors at time t=0, corresponding to the peak.

Updated on:February 03,2024