Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on: January 12,2024

Research reveals how sleep disruption can exacerbate pain

byMassachusetts General HospitalCSD induces hyperalgesia.aExperimental diagram of the sleep deprivation experiment and behavioral testing.bSample EEG recording using wire

Updated on:January 12,2024

Alzheimer's and dementia: Understand wandering and how to address it

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWandering and becoming lost is common among people with Alzheimer's disease or other disorders causing dementia. This behavior can happen i

Updated on: April 20,2024

Alzheimer's and dementia: Understand wandering and how to address it

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWandering and becoming lost is common among people with Alzheimer's disease or other disorders causing dementia. This behavior can happen i

Updated on:April 20,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on: April 20,2024

Alzheimer's or Lewy body dementia? How patients draw can help determine the type of dementia

by University of TsukubaCredit: AI-generated imageThe two most common neurodegenerative dementias are Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). There is often an overlap o

Updated on:April 20,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on: February 05,2024

A new mechanism for crossing the blood–brain barrier

by Lori Dajose,California Institute of TechnologyCA-IV is required for the CNS potency of Car4-dependent AAV. (A) Immunostaining for CA-IV in the brains of WT/WT and KO/KO Car4 mice. Magnified r

Updated on:February 05,2024

ANKRD55: A new gene involved in Multiple Sclerosis is discovered

by University of the Basque CountryThis image shows intracellular localization of ANKRD55 in Jurkat, SH-SY5Y and PMA-treated U937 cells. Credit: Koen VandenbroeckMultiple Sclerosis (MS) is a neur

Updated on: March 26,2024

ANKRD55: A new gene involved in Multiple Sclerosis is discovered

by University of the Basque CountryThis image shows intracellular localization of ANKRD55 in Jurkat, SH-SY5Y and PMA-treated U937 cells. Credit: Koen VandenbroeckMultiple Sclerosis (MS) is a neur

Updated on:March 26,2024

Untangling the threads of early onset dementia

by Lynda De Widt, Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainChanges in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementi

Updated on: April 06,2024

Untangling the threads of early onset dementia

by Lynda De Widt, Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainChanges in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementi

Updated on:April 06,2024

Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows

by Nagoya City UniversityCollective time-lapse images of a migrating neuron (bottom) and an elongating axon (top) from super-resolution microscopy. Growth cones at the tips of the neurons are ext

Updated on: March 19,2024

Growth cone in migrating neurons involved in promoting neuronal migration and regeneration in brain injury, study shows

by Nagoya City UniversityCollective time-lapse images of a migrating neuron (bottom) and an elongating axon (top) from super-resolution microscopy. Growth cones at the tips of the neurons are ext

Updated on:March 19,2024

Power of light and oxygen clears Alzheimer's disease protein in live mice

by University of TokyoCredit: Unsplash/CC0 Public DomainA small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the b

Updated on: June 05,2024

Power of light and oxygen clears Alzheimer's disease protein in live mice

by University of TokyoCredit: Unsplash/CC0 Public DomainA small, light-activated molecule recently tested in mice represents a new approach to eliminating clumps of amyloid protein found in the b

Updated on:June 05,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on: April 02,2024

Tau PET: A window into the future of Alzheimer's patients

by University of GenevaTau imaging with 18F-Flortaucipir PET in Alzheimer’s disease. The figure shows a prototypical tau accumulation pattern, obtained by comparing tau load of patients with Alzh

Updated on:April 02,2024

Playtime, being social helps a dog's aging brain, study finds

by Dennis ThompsonAs their aging brains shrink, older dogs can suffer the same memory and thinking problems as many older humans do.But dogs are just like humans in another way—playtime and social act

Updated on: April 06,2024

Playtime, being social helps a dog's aging brain, study finds

by Dennis ThompsonAs their aging brains shrink, older dogs can suffer the same memory and thinking problems as many older humans do.But dogs are just like humans in another way—playtime and social act

Updated on:April 06,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on: January 21,2024

'Abnormal' protein could be common link between all forms of motor neuron disease

byUniversity of SydneyAbnormal SOD1 protein detected in human spinal cord tissue (dark spots). Credit: Trist et al. 2022.Researchers have found an abnormal protein usually linked to a rare inher

Updated on:January 21,2024