Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on: May 22,2024

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on:May 22,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on: May 13,2024

Bench-to-bedside drug design could lead to new Alzheimer's disease treatments

by University of GlasgowCredit: CC0 Public DomainAn international team of scientists and pharmaceutical collaborators has made a breakthrough "bench to bedside" discovery, ten years in

Updated on:May 13,2024

More amyloid in the brain, more cognitive decline

by University of Texas at DallasCredit: copyright American Heart AssociationA new study from the Center for Vital Longevity at The University of Texas at Dallas has found that the amount of amylo

Updated on: May 18,2024

More amyloid in the brain, more cognitive decline

by University of Texas at DallasCredit: copyright American Heart AssociationA new study from the Center for Vital Longevity at The University of Texas at Dallas has found that the amount of amylo

Updated on:May 18,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on: August 08,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on:August 08,2024

Scientists define new type of memory loss in older adults

byMayo ClinicGraphical abstract. Credit:(2024). DOI: 10.1093/braincomms/fcae183Researchers at Mayo Clinic have established new criteria for a memory-loss syndrome in older adults that spec

Updated on: July 31,2024

Scientists define new type of memory loss in older adults

byMayo ClinicGraphical abstract. Credit:(2024). DOI: 10.1093/braincomms/fcae183Researchers at Mayo Clinic have established new criteria for a memory-loss syndrome in older adults that spec

Updated on:July 31,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on: June 01,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on:June 01,2024

Approximately half of AD dementia cases are mild, one-fifth are severe

by Boston University School of MedicineCredit: CC0 Public DomainWhat percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are

Updated on: May 20,2024

Approximately half of AD dementia cases are mild, one-fifth are severe

by Boston University School of MedicineCredit: CC0 Public DomainWhat percent of patients with Alzheimer's Disease (AD) currently have severe dementia? Do more people have mild disease? Or are

Updated on:May 20,2024

Single dual time-point PET scan identifies dual Alzheimer's biomarkers

by Society of Nuclear MedicineWhile subject #1 (left) was judged as positive for both the neuronal injury and the amyloid load biomarker, both Alzheimer's disease biomarkers were negative in

Updated on: May 20,2024

Single dual time-point PET scan identifies dual Alzheimer's biomarkers

by Society of Nuclear MedicineWhile subject #1 (left) was judged as positive for both the neuronal injury and the amyloid load biomarker, both Alzheimer's disease biomarkers were negative in

Updated on:May 20,2024

Mediterranean diet associated with decreased risk of dementia

by Newcastle UniversityCredit: CC0 Public DomainEating a traditional Mediterranean-type diet—rich in foods such as seafood, fruit, and nuts—may help reduce the risk of dementia by almost a quarte

Updated on: May 20,2024

Mediterranean diet associated with decreased risk of dementia

by Newcastle UniversityCredit: CC0 Public DomainEating a traditional Mediterranean-type diet—rich in foods such as seafood, fruit, and nuts—may help reduce the risk of dementia by almost a quarte

Updated on:May 20,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on: April 20,2024

Depression in Alzheimer's has different risk factors than depression in those without dementia

by University of BristolGDS trajectory analysis in NACC (A). Individuals with persistent depressive symptoms during follow-up (group 5) appeared to have more apathy (C), anxiety (D), and NPI rate

Updated on:April 20,2024

New study reveals limited public understanding of dementia globally

by Trinity College DublinBelieving that dementia is a normal part of aging is the most common misconception about dementia, according to a new study conducted by researchers at Trinity College Du

Updated on: February 26,2024

New study reveals limited public understanding of dementia globally

by Trinity College DublinBelieving that dementia is a normal part of aging is the most common misconception about dementia, according to a new study conducted by researchers at Trinity College Du

Updated on:February 26,2024