Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on: May 22,2024

Gene therapy using 'zinc fingers' may help treat Alzheimer's disease, animal study shows

by Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainResearchers have used a genetic engineering strategy to dramatically reduce levels of tau—a key protein that accumulates and beco

Updated on:May 22,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on: January 11,2024

Study associates reduced activity of a key enzyme with microcephaly in Zika-infected offspring

byFAPESPCredit:Journal of Neurochemistry(2023). DOI: 10.1111/jnc.15918Mice that were infected with Zika virus during pregnancy and developed microcephaly displayed less activity of N

Updated on:January 11,2024

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on: March 02,2024

Could a breakdown in the brain's networks allow infections to contribute to Alzheimer's disease?

by Drexel UniversityCartoon of the LDA algorithm. Credit:Frontiers in Cellular and Infection Microbiology(2023). DOI: 10.3389/fcimb.2023.1123228The human microbiome includes the genet

Updated on:March 02,2024

Congenital cytomegalovirus infection: Study successfully implements pooled saliva tests

by Hebrew University of JerusalemSchematic presentation of neonatal cCMV screening algorithms at the Hadassah Medical Center.a, Targeted screening algorithm of suspected neonates by convent

Updated on: March 19,2024

Congenital cytomegalovirus infection: Study successfully implements pooled saliva tests

by Hebrew University of JerusalemSchematic presentation of neonatal cCMV screening algorithms at the Hadassah Medical Center.a, Targeted screening algorithm of suspected neonates by convent

Updated on:March 19,2024

Researchers identify key genes in the development of the primate brain

by Bill Hathaway,Yale UniversityRegionalization of macaque telencephalon. Single-cell transcriptomics of prenatal macaque telencephalic regions distinguished subtypes spanning development. The t

Updated on: January 12,2024

Researchers identify key genes in the development of the primate brain

by Bill Hathaway,Yale UniversityRegionalization of macaque telencephalon. Single-cell transcriptomics of prenatal macaque telencephalic regions distinguished subtypes spanning development. The t

Updated on:January 12,2024

Alzheimer's disease: Viagra is seen as a potential treatment, but the research shows contradictory findings

by Ian Maidment and Hayley Gorton,The ConversationCredit: CC0 Public DomainArecent study reportedthat sildenafil, sold under the brand name Viagra, and other medicines from the same

Updated on: March 22,2024

Alzheimer's disease: Viagra is seen as a potential treatment, but the research shows contradictory findings

by Ian Maidment and Hayley Gorton,The ConversationCredit: CC0 Public DomainArecent study reportedthat sildenafil, sold under the brand name Viagra, and other medicines from the same

Updated on:March 22,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on: January 12,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on:January 12,2024

Alzheimer's breakthrough: Brain metals that may drive disease progression revealed

by University of WarwickIn brains affected by Alzheimer's, researchers identify chemically reduced iron species, with mineral forms including a magnetic iron oxide which they hypothesize are

Updated on: April 18,2024

Alzheimer's breakthrough: Brain metals that may drive disease progression revealed

by University of WarwickIn brains affected by Alzheimer's, researchers identify chemically reduced iron species, with mineral forms including a magnetic iron oxide which they hypothesize are

Updated on:April 18,2024

New research finds a direct communication path between the lungs and the brain

byUniversity of CalgaryCredit:Cell(2024). DOI: 10.1016/j.cell.2024.03.001University of Calgary researchers have discovered the lungs communicate directly with the brain when there is

Updated on: March 28,2024

New research finds a direct communication path between the lungs and the brain

byUniversity of CalgaryCredit:Cell(2024). DOI: 10.1016/j.cell.2024.03.001University of Calgary researchers have discovered the lungs communicate directly with the brain when there is

Updated on:March 28,2024

Family caregivers find support on #dementia TikTok

by Kate WellsCredit: Unsplash/CC0 Public DomainIt all changed on a Saturday night in New York City in 2016. Jacquelyn Revere was 29 and headed out to attend a friend's comedy show. She was on the

Updated on: June 20,2024

Family caregivers find support on #dementia TikTok

by Kate WellsCredit: Unsplash/CC0 Public DomainIt all changed on a Saturday night in New York City in 2016. Jacquelyn Revere was 29 and headed out to attend a friend's comedy show. She was on the

Updated on:June 20,2024

A new model to predict brain development

by Paris Brain InstituteRepresentation of the cerebral development in C. elegans as a statio-temporal topographical map. Credit: Vito Dichio, Fabrizio De Vico Fallani.From the very first weeks of

Updated on: March 19,2024

A new model to predict brain development

by Paris Brain InstituteRepresentation of the cerebral development in C. elegans as a statio-temporal topographical map. Credit: Vito Dichio, Fabrizio De Vico Fallani.From the very first weeks of

Updated on:March 19,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on: June 01,2024

Fecal implants drive behavioral and cognitive changes in Alzheimer's model

by Erik Robinson,Oregon Health & Science UniversityCredit: CC0 Public DomainNew research in mice for the first time draws a definitive causal connection between changes in the gut microbiome

Updated on:June 01,2024