Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on: April 25,2024

Chaperone protein imbalance promotes toxic tau buildup in the aging brain

by University of South FloridaTau pathology resembling that seen in Alzheimer's disease brains. Credit: Laura Blair's laboratory, USF Health/University of South FloridaChaperone protein i

Updated on:April 25,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on: January 12,2024

How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on:January 12,2024

New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on: February 05,2024

New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on:February 05,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on: April 02,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on:April 02,2024

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on: May 17,2024

Microbes may hold the key for treating neurological disorders

by Baylor College of MedicineCredit: Pixabay/CC0 Public DomainWhen we think about the causes of neurological disorders and how to treat them, we think about targeting the brain. But is this the b

Updated on:May 17,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on: February 27,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on:February 27,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on: April 20,2024

How the discovery of an Alzheimer's tipping point could improve drug trials

by Robin Marks,University of California, San FranciscoDormant tau proteins in the brain's memory centers (red) are spurred to spread as amyloid beta (blue) develops in the neocortex. When th

Updated on:April 20,2024

Alzheimer's disease: Viagra is seen as a potential treatment, but the research shows contradictory findings

by Ian Maidment and Hayley Gorton,The ConversationCredit: CC0 Public DomainArecent study reportedthat sildenafil, sold under the brand name Viagra, and other medicines from the same

Updated on: March 22,2024

Alzheimer's disease: Viagra is seen as a potential treatment, but the research shows contradictory findings

by Ian Maidment and Hayley Gorton,The ConversationCredit: CC0 Public DomainArecent study reportedthat sildenafil, sold under the brand name Viagra, and other medicines from the same

Updated on:March 22,2024

Molecular pathology of suicide: A postmortem study

byUniversity of AmsterdamCredit: Pixabay/CC0 Public DomainWhat changes in the brains of people who commit or think about committing suicide? Ph.D. candidate Lin Zhang investigated at a molecular

Updated on: January 12,2024

Molecular pathology of suicide: A postmortem study

byUniversity of AmsterdamCredit: Pixabay/CC0 Public DomainWhat changes in the brains of people who commit or think about committing suicide? Ph.D. candidate Lin Zhang investigated at a molecular

Updated on:January 12,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on: July 05,2024

How our blood-brain barrier stops bugs and toxins getting to our brain

by Sebastian Furness,The ConversationCredit: Unsplash/CC0 Public DomainOur brain is an extremely complex and delicate organ. Our body fiercely protects it by holding onto things that help it and

Updated on:July 05,2024

Activity is important for your brain and for the prevention of Alzheimer's, suggests neurovascular study

by University of Copenhagen"By staying active, we are able to maintain a healthy vascular system so that the blood vessels stay flexible and retain the ability to drive forward the cerebrosp

Updated on: March 02,2024

Activity is important for your brain and for the prevention of Alzheimer's, suggests neurovascular study

by University of Copenhagen"By staying active, we are able to maintain a healthy vascular system so that the blood vessels stay flexible and retain the ability to drive forward the cerebrosp

Updated on:March 02,2024