FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on: November 22,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on:November 22,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on: March 07,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on:March 07,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on: January 12,2024

How a single synapse transmits both visual and subconscious information to the brain of fruit flies

by Justin Jackson , Medical XpressACh and histamine act on distinct neurons. Credit:Nature(2023). DOI: 10.1038/s41586-023-06681-6Research led by Peking University, China, has discovered a

Updated on:January 12,2024

New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on: February 05,2024

New insights into the role of the different meningeal layers in autoimmune-inflammatory diseases

by Stefan Weller, Universitätsmedizin Göttingen - Georg-August-UniversitätAuthors of the publication: (f. l.) Prof. Dr. Alexander Flügel (Institute Director), Dr. Arianna Merlini (First author, postdo

Updated on:February 05,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on: April 25,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on:April 25,2024

Eating less processed red meat could cut your odds for dementia

by Ernie MundellSkip the bacon and those holiday hot dogs: A new study finds eating processed red meats raises your odds for dementia.Overall, just two servings per week of processed red meat was link

Updated on: August 31,2024

Eating less processed red meat could cut your odds for dementia

by Ernie MundellSkip the bacon and those holiday hot dogs: A new study finds eating processed red meats raises your odds for dementia.Overall, just two servings per week of processed red meat was link

Updated on:August 31,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on: April 28,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on:April 28,2024

Professor discusses what's new in concussion treatment and management

by Laura Bailey,University of MichiganCredit: Unsplash/CC0 Public DomainThere have been significant changes in the last few years in how concussions are identified and treated. Steven Broglio, d

Updated on: March 30,2024

Professor discusses what's new in concussion treatment and management

by Laura Bailey,University of MichiganCredit: Unsplash/CC0 Public DomainThere have been significant changes in the last few years in how concussions are identified and treated. Steven Broglio, d

Updated on:March 30,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on: July 08,2024

Finding the sweet spot in brain development: Study discovers receptor protein regulates timing of temporary connections

by Luis Sandoval,Cold Spring Harbor LaboratoryA cross-section of the somatosensory cortex in a young mouse brain. A key receptor protein named mGluR1 (green) is necessary to prime sensory circui

Updated on:July 08,2024

Gene identified that could help prevent or delay onset of Alzheimer's disease

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: Pixabay/CC0 Public DomainFindings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City o

Updated on: June 14,2024

Gene identified that could help prevent or delay onset of Alzheimer's disease

by Steve Yozwiak,The Translational Genomics Research InstituteCredit: Pixabay/CC0 Public DomainFindings of a study by the Translational Genomics Research Institute (TGen), an affiliate of City o

Updated on:June 14,2024