Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on: March 28,2024

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on:March 28,2024

Poor sleep among African Americans associated with diminished cognitive function

by RAND CorporationCredit: Unsplash/CC0 Public DomainMore fragmented sleep and longer periods of wakefulness after bedtime among a group of low-income African American adults were associated with

Updated on: June 01,2024

Poor sleep among African Americans associated with diminished cognitive function

by RAND CorporationCredit: Unsplash/CC0 Public DomainMore fragmented sleep and longer periods of wakefulness after bedtime among a group of low-income African American adults were associated with

Updated on:June 01,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024

Often overlooked stem cells hold hidden powers for blood disease treatments

by King Abdullah University of Science and TechnologyResearchers have identified a method to enhance the regenerative capabilities of stem cells found in umbilical cord blood, which could have be

Updated on: March 19,2024

Often overlooked stem cells hold hidden powers for blood disease treatments

by King Abdullah University of Science and TechnologyResearchers have identified a method to enhance the regenerative capabilities of stem cells found in umbilical cord blood, which could have be

Updated on:March 19,2024

Treatment option for Alzheimer's disease possible

by University of ManchesterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A research project has shown that an experimental model of Alzheimer'

Updated on: April 08,2024

Treatment option for Alzheimer's disease possible

by University of ManchesterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A research project has shown that an experimental model of Alzheimer'

Updated on:April 08,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Consistent gene changes in Alzheimer's disease across studies

by Society for NeuroscienceTop 20 up and down-regulated genes for late phase Alzheimer's disease. Credit: Zhuang et al.,eNeuro2019A comparison of mouse Alzheimer's disease mod

Updated on: April 16,2024

Consistent gene changes in Alzheimer's disease across studies

by Society for NeuroscienceTop 20 up and down-regulated genes for late phase Alzheimer's disease. Credit: Zhuang et al.,eNeuro2019A comparison of mouse Alzheimer's disease mod

Updated on:April 16,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on: April 16,2024

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on:April 16,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on: March 30,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on:March 30,2024

White matter may aid recovery from spinal cord injuries: Study

by Bill Snyder,Vanderbilt University Medical CenterCredit: CC0 Public DomainInjuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability.

Updated on: August 26,2024

White matter may aid recovery from spinal cord injuries: Study

by Bill Snyder,Vanderbilt University Medical CenterCredit: CC0 Public DomainInjuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability.

Updated on:August 26,2024

Risk factors for faster aging in the brain revealed in new study

by University of OxfordTo the left of the figure, the red-yellow color denotes the regions that degenerate earlier than the rest of the brain, and are vulnerable to Alzheimer's disease. These

Updated on: March 30,2024

Risk factors for faster aging in the brain revealed in new study

by University of OxfordTo the left of the figure, the red-yellow color denotes the regions that degenerate earlier than the rest of the brain, and are vulnerable to Alzheimer's disease. These

Updated on:March 30,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on: February 27,2024

Inflammatory changes in the brain twenty years before Alzheimer onset

by Karolinska InstitutetSome of the researcher's PET-images.Roughly twenty years before the first symptoms of Alzheimer's disease appear, inflammatory changes in the brain can be seen, ac

Updated on:February 27,2024