Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on: June 01,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on:June 01,2024

Carriers of Alzheimer's genetic marker have greater difficulty harnessing past knowledge

by Baycrest Centre for Geriatric CareDr. Claude Alain, a senior author on the paper and senior scientist at Baycrest's Rotman Research Institute. Credit: Provided by Baycrest.Adults carrying

Updated on: April 23,2024

Carriers of Alzheimer's genetic marker have greater difficulty harnessing past knowledge

by Baycrest Centre for Geriatric CareDr. Claude Alain, a senior author on the paper and senior scientist at Baycrest's Rotman Research Institute. Credit: Provided by Baycrest.Adults carrying

Updated on:April 23,2024

Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia

by St. Michael's HospitalCredit: CC0 Public DomainFor patients with dementia who have symptoms of aggression and agitation, interventions such as outdoor activities, massage and touch therapy

Updated on: June 01,2024

Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia

by St. Michael's HospitalCredit: CC0 Public DomainFor patients with dementia who have symptoms of aggression and agitation, interventions such as outdoor activities, massage and touch therapy

Updated on:June 01,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on: January 12,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on:January 12,2024

ssResearchers identify key steps to toxic protein accumulation in Alzheimer's and other diseases

by Tamara Bhandari,Washington University School of Medicine in St. LouisStress granules (red) fill stem cell-derived neurons (nuclei shown in blue) from a person with a mutation in the tau gene.

Updated on: March 02,2024

ssResearchers identify key steps to toxic protein accumulation in Alzheimer's and other diseases

by Tamara Bhandari,Washington University School of Medicine in St. LouisStress granules (red) fill stem cell-derived neurons (nuclei shown in blue) from a person with a mutation in the tau gene.

Updated on:March 02,2024

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on: July 31,2024

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on:July 31,2024

Differences in blood biomarkers in people with genetic risk of Alzheimer's

by Ali Howard,University of GlasgowPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers at the University of Glasgow have conducted the largest study to date

Updated on: April 23,2024

Differences in blood biomarkers in people with genetic risk of Alzheimer's

by Ali Howard,University of GlasgowPET scan of a human brain with Alzheimer's disease. Credit: public domainResearchers at the University of Glasgow have conducted the largest study to date

Updated on:April 23,2024

In quiet debut, Alzheimer's drug finds questions, skepticism

by Tom MurphyThis image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. The first new Alzheimer's treatment in more than 20 years was hailed as a breakt

Updated on: April 23,2024

In quiet debut, Alzheimer's drug finds questions, skepticism

by Tom MurphyThis image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. The first new Alzheimer's treatment in more than 20 years was hailed as a breakt

Updated on:April 23,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on: January 12,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on:January 12,2024

Blood-based biomarkers for Alzheimer's disease: Study in China

by Science China PressA total of 817 participants were recruited to evaluate potential alterations in blood-based biomarkers for AD among different clinical groups, including AD dementia, non-AD

Updated on: April 08,2024

Blood-based biomarkers for Alzheimer's disease: Study in China

by Science China PressA total of 817 participants were recruited to evaluate potential alterations in blood-based biomarkers for AD among different clinical groups, including AD dementia, non-AD

Updated on:April 08,2024

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on: March 26,2024

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on:March 26,2024