Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on: January 11,2024

Novel Rett syndrome variant shines light on new screening strategies for therapies

byTexas Children's HospitalMeCP2 protein level is reduced in the patient fibroblast-derived neurons. (A) Diagram of MeCP2 protein with the G118E mutation in the methyl-CpG binding domain (MB

Updated on:January 11,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024

Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease

by American Academy of NeurologyCredit: CC0 Public DomainThe drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study p

Updated on: June 01,2024

Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease

by American Academy of NeurologyCredit: CC0 Public DomainThe drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study p

Updated on:June 01,2024

Anticoagulants fail to prevent unexplained strokes, clinical trial finds

by Columbia University Irving Medical CenterVisual Abstract.Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy. Credit:JAMA, (2024). doi:10.10

Updated on: May 21,2024

Anticoagulants fail to prevent unexplained strokes, clinical trial finds

by Columbia University Irving Medical CenterVisual Abstract.Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy. Credit:JAMA, (2024). doi:10.10

Updated on:May 21,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on: February 03,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on:February 03,2024

Neuralink shows quadriplegic playing chess with brain implant

Elon Musk's Neuralink startup designed a surgical robot to implant devices into brains to link them to computers.Neuralink on Wednesday streamed a video of its first human patient playing computer

Updated on: March 28,2024

Neuralink shows quadriplegic playing chess with brain implant

Elon Musk's Neuralink startup designed a surgical robot to implant devices into brains to link them to computers.Neuralink on Wednesday streamed a video of its first human patient playing computer

Updated on:March 28,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

Marriage is linked to reduced dementia risk

by Alzheimer's Research UKResearchers from University College London have found that people who are single or widowed are at a greater risk of dementia than people who are married. The resear

Updated on: March 07,2024

Marriage is linked to reduced dementia risk

by Alzheimer's Research UKResearchers from University College London have found that people who are single or widowed are at a greater risk of dementia than people who are married. The resear

Updated on:March 07,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on: May 12,2024

Optimizing Dysphagia Management in Ischemic Stroke Patients: Insights from a Retrospective Study

Updated on:May 12,2024

Fluctuating levels of cholesterol and triglycerides linked to increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainOlder people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and re

Updated on: May 20,2024

Fluctuating levels of cholesterol and triglycerides linked to increased risk of dementia

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainOlder people who have fluctuating levels of cholesterol and triglycerides may have a higher risk of Alzheimer's disease and re

Updated on:May 20,2024

Biogen cuts the price tag on its Alzheimer's drug in half

by Tom MurphyThe Biogen Inc., headquarters is shown March 11, 2020, in Cambridge, Mass. Biogen is slashing the price of its Alzheimer's treatment months after the drug debuted to widespread critic

Updated on: April 25,2024

Biogen cuts the price tag on its Alzheimer's drug in half

by Tom MurphyThe Biogen Inc., headquarters is shown March 11, 2020, in Cambridge, Mass. Biogen is slashing the price of its Alzheimer's treatment months after the drug debuted to widespread critic

Updated on:April 25,2024

Aging reduces the ability of regulatory T cells to enhance myelin regeneration, study finds

byMiguel Hernandez University of ElcheA Diagram explaining the experimental design of in vivo Treg depletion, Treg adoptive transfer and spinal cord demyelination. Representative images of immun

Updated on: March 28,2024

Aging reduces the ability of regulatory T cells to enhance myelin regeneration, study finds

byMiguel Hernandez University of ElcheA Diagram explaining the experimental design of in vivo Treg depletion, Treg adoptive transfer and spinal cord demyelination. Representative images of immun

Updated on:March 28,2024