In quiet debut, Alzheimer's drug finds questions, skepticism

by Tom MurphyThis image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. The first new Alzheimer's treatment in more than 20 years was hailed as a breakt

Updated on: April 23,2024

In quiet debut, Alzheimer's drug finds questions, skepticism

by Tom MurphyThis image provided by Biogen on Monday, June 7, 2021 shows a vial and packaging for the drug Aduhelm. The first new Alzheimer's treatment in more than 20 years was hailed as a breakt

Updated on:April 23,2024

Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia

by St. Michael's HospitalCredit: CC0 Public DomainFor patients with dementia who have symptoms of aggression and agitation, interventions such as outdoor activities, massage and touch therapy

Updated on: June 01,2024

Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia

by St. Michael's HospitalCredit: CC0 Public DomainFor patients with dementia who have symptoms of aggression and agitation, interventions such as outdoor activities, massage and touch therapy

Updated on:June 01,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

Researchers define seizure burden, developmental outcomes for STXBP1-related disorders

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) found that seizure patterns and response to treatment st

Updated on: June 24,2024

Researchers define seizure burden, developmental outcomes for STXBP1-related disorders

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) found that seizure patterns and response to treatment st

Updated on:June 24,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on: January 12,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on:January 12,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on: April 18,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on:April 18,2024

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on: July 31,2024

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on:July 31,2024

Carriers of Alzheimer's genetic marker have greater difficulty harnessing past knowledge

by Baycrest Centre for Geriatric CareDr. Claude Alain, a senior author on the paper and senior scientist at Baycrest's Rotman Research Institute. Credit: Provided by Baycrest.Adults carrying

Updated on: April 23,2024

Carriers of Alzheimer's genetic marker have greater difficulty harnessing past knowledge

by Baycrest Centre for Geriatric CareDr. Claude Alain, a senior author on the paper and senior scientist at Baycrest's Rotman Research Institute. Credit: Provided by Baycrest.Adults carrying

Updated on:April 23,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on: January 12,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on:January 12,2024

Cognitive impairment afflicts majority of stroke patients

by Wenche Margrethe Kulmo,Norwegian University of Science and TechnologyCredit: Marcus Aurelius from PexelsParalysis and difficulty speaking are well-known problems following a stroke. Establish

Updated on: February 18,2024

Cognitive impairment afflicts majority of stroke patients

by Wenche Margrethe Kulmo,Norwegian University of Science and TechnologyCredit: Marcus Aurelius from PexelsParalysis and difficulty speaking are well-known problems following a stroke. Establish

Updated on:February 18,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on: April 25,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on:April 25,2024

ssResearchers identify key steps to toxic protein accumulation in Alzheimer's and other diseases

by Tamara Bhandari,Washington University School of Medicine in St. LouisStress granules (red) fill stem cell-derived neurons (nuclei shown in blue) from a person with a mutation in the tau gene.

Updated on: March 02,2024

ssResearchers identify key steps to toxic protein accumulation in Alzheimer's and other diseases

by Tamara Bhandari,Washington University School of Medicine in St. LouisStress granules (red) fill stem cell-derived neurons (nuclei shown in blue) from a person with a mutation in the tau gene.

Updated on:March 02,2024