Super ager brains contain 'super neurons'

by Northwestern UniversityCredit: Pixabay/CC0 Public DomainNeurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 yea

Updated on: February 03,2024

Super ager brains contain 'super neurons'

by Northwestern UniversityCredit: Pixabay/CC0 Public DomainNeurons in an area of the brain responsible for memory (known as the entorhinal cortex) were significantly larger in super agers (80 yea

Updated on:February 03,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on: June 18,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on:June 18,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on: November 22,2024

FDA grants orphan drug designation to potential treatment of STXBP1 developmental and epileptic encephalopathy

by Graciela Gutierrez,Baylor College of MedicineDNA, which has a double-helix structure, can have many genetic mutations and variations. Credit: NIHResearch that was carried out by Baylor Colleg

Updated on:November 22,2024

Gut could sound early warning alarm for motor neuron disease

by University of AberdeenCredit: Pixabay/CC0 Public DomainThe same proteins thought to contribute to motor neuron disease can be found in the gut many years before any brain symptoms occur, a new

Updated on: February 03,2024

Gut could sound early warning alarm for motor neuron disease

by University of AberdeenCredit: Pixabay/CC0 Public DomainThe same proteins thought to contribute to motor neuron disease can be found in the gut many years before any brain symptoms occur, a new

Updated on:February 03,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on: April 18,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on:April 18,2024

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on: April 10,2024

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on:April 10,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on: April 28,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on:April 28,2024

Study finds high prevalence of hidden brain changes in people with heart disease

byGeorge Institute for Global HealthCredit: Pixabay/CC0 Public DomainA new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of str

Updated on: March 28,2024

Study finds high prevalence of hidden brain changes in people with heart disease

byGeorge Institute for Global HealthCredit: Pixabay/CC0 Public DomainA new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of str

Updated on:March 28,2024

A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on: April 16,2024

A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on:April 16,2024

Family caregivers find support on #dementia TikTok

by Kate WellsCredit: Unsplash/CC0 Public DomainIt all changed on a Saturday night in New York City in 2016. Jacquelyn Revere was 29 and headed out to attend a friend's comedy show. She was on the

Updated on: June 20,2024

Family caregivers find support on #dementia TikTok

by Kate WellsCredit: Unsplash/CC0 Public DomainIt all changed on a Saturday night in New York City in 2016. Jacquelyn Revere was 29 and headed out to attend a friend's comedy show. She was on the

Updated on:June 20,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on: March 02,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on:March 02,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024