Newly discovered mechanism reveals NAD's role in aging and disease

byUniversity of BergenProposed model for the cooperation of SLC25A51 and NMNAT3 to buffer cellular NAD+fluctuations. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-024-011

Updated on: February 01,2025 0

Newly discovered mechanism reveals NAD's role in aging and disease

byUniversity of BergenProposed model for the cooperation of SLC25A51 and NMNAT3 to buffer cellular NAD+fluctuations. Credit:Nature Metabolism(2024). DOI: 10.1038/s42255-024-011

Updated on:February 01,2025 0

Early biomarker found for degenerative neurologic disease

by Society of Nuclear Medicine and Molecular ImagingPI-2620 binding expressed as distribution volume ratios from multilinear reference tissue modeling 2. Axial and sagittal slices from averaged groups

Updated on: June 01,2024 8

Early biomarker found for degenerative neurologic disease

by Society of Nuclear Medicine and Molecular ImagingPI-2620 binding expressed as distribution volume ratios from multilinear reference tissue modeling 2. Axial and sagittal slices from averaged groups

Updated on:June 01,2024 8

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on: March 30,2024 15

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on:March 30,2024 15

Molecular changes in the brain in aftermath of traumatic event may help explain long-term susceptibility or resilience

by Medical College of Georgia at Augusta UniversityDr. Chung Sub Kim. Credit: Michael Holahan, Augusta UniversitySocial avoidance is a common symptom of PTSD, and scientists working to better und

Updated on: February 05,2024 12

Molecular changes in the brain in aftermath of traumatic event may help explain long-term susceptibility or resilience

by Medical College of Georgia at Augusta UniversityDr. Chung Sub Kim. Credit: Michael Holahan, Augusta UniversitySocial avoidance is a common symptom of PTSD, and scientists working to better und

Updated on:February 05,2024 12

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on: April 22,2024 0

Scientists identify mutated gene behind mirror movement disorder

byUniversity of MontrealArhgef7 is required for Netrin-1–mediated commissural axon guidance. (A) The mean mRNA expression, fragments per kilobase of transcript per million mapped reads (fpkm), (

Updated on:April 22,2024 0

Pathway deep in the brain makes it resilient after injury

by Sarah Williams,Gladstone InstitutesA new study led by Gladstone researchers suggests that targeting a protein in the thalamus could prevent the long-term damage that follows traumatic brain i

Updated on: February 21,2024 16

Pathway deep in the brain makes it resilient after injury

by Sarah Williams,Gladstone InstitutesA new study led by Gladstone researchers suggests that targeting a protein in the thalamus could prevent the long-term damage that follows traumatic brain i

Updated on:February 21,2024 16

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on: April 18,2024 18

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on:April 18,2024 18

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on: April 02,2024 20

Tau hot spots open new avenues of discovery into dementia

by Queensland Brain InstituteRepresentative diffraction-limited image of a neuroblastoma cell expressing Tau-mEos3.2 molecules acquired in the green channel before single-molecule imaging. Credit: Dr

Updated on:April 02,2024 20

Research team identifies new treatment target for Alzheimer's disease

byLancaster UniversityAlzheimer's disease is the leading cause of dementia and disability in old age. Credit: Lancaster UniversityResearchers at the University of Leeds and Lancaster Univers

Updated on: March 28,2024 0

Research team identifies new treatment target for Alzheimer's disease

byLancaster UniversityAlzheimer's disease is the leading cause of dementia and disability in old age. Credit: Lancaster UniversityResearchers at the University of Leeds and Lancaster Univers

Updated on:March 28,2024 0

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on: April 16,2024 14

Good news, bad news from Alzheimer's vaccine trial

by Marianne Madeiros and Robin FosterAn experimental Alzheimer's vaccine appears to safely clear abnormal tau protein from the brain, but it's not yet clear whether the shot will be able to sa

Updated on:April 16,2024 14

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on: March 19,2024 10

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on:March 19,2024 10

Antipsychotic drugs likely overprescribed to homebound patients with dementia, study finds

by WileyCredit: CC0 Public DomainNew research published in theJournal of the American Geriatrics Societyindicates that antipsychotics are likely overprescribed and used inappropriatel

Updated on: March 02,2024 15

Antipsychotic drugs likely overprescribed to homebound patients with dementia, study finds

by WileyCredit: CC0 Public DomainNew research published in theJournal of the American Geriatrics Societyindicates that antipsychotics are likely overprescribed and used inappropriatel

Updated on:March 02,2024 15