Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on: January 10,2024

Researchers discover new molecular drug targets for progressive neurological disorder

by Lynda De Widt,Mayo ClinicSingle-nucleus RNAseq captures glial expression changes in PSP brains. a Nuclei in UMAP space colored by cluster number and grouped by its cell type. b Average expres

Updated on:January 10,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024

First U.S. clinical trial using adult allogeneic stem cells to treat Alzheimer's disease

by Emory UniversityA new study to assess the safety, tolerability and preliminary efficacy of allogeneic stem cells in persons with mild to moderate dementia due to Alzheimer's disease (AD) i

Updated on: March 07,2024

First U.S. clinical trial using adult allogeneic stem cells to treat Alzheimer's disease

by Emory UniversityA new study to assess the safety, tolerability and preliminary efficacy of allogeneic stem cells in persons with mild to moderate dementia due to Alzheimer's disease (AD) i

Updated on:March 07,2024

How do we decide what to look at next? A computational model has the answer

byTechnical University of BerlinObject-based scanpath simulation in dynamic scenes. Credit: The image is derived from a frame of the field03 video of the VidCom dataset (Permission to Publish Co

Updated on: January 11,2024

How do we decide what to look at next? A computational model has the answer

byTechnical University of BerlinObject-based scanpath simulation in dynamic scenes. Credit: The image is derived from a frame of the field03 video of the VidCom dataset (Permission to Publish Co

Updated on:January 11,2024

Poor sleep among African Americans associated with diminished cognitive function

by RAND CorporationCredit: Unsplash/CC0 Public DomainMore fragmented sleep and longer periods of wakefulness after bedtime among a group of low-income African American adults were associated with

Updated on: June 01,2024

Poor sleep among African Americans associated with diminished cognitive function

by RAND CorporationCredit: Unsplash/CC0 Public DomainMore fragmented sleep and longer periods of wakefulness after bedtime among a group of low-income African American adults were associated with

Updated on:June 01,2024

Cooperation advances Alzheimer's disease prevention research

by GYMRThe future success of Alzheimer's prevention research could depend on the ability of researchers from different clinical trials to build collaborative relationships that facilitate the shar

Updated on: February 26,2024

Cooperation advances Alzheimer's disease prevention research

by GYMRThe future success of Alzheimer's prevention research could depend on the ability of researchers from different clinical trials to build collaborative relationships that facilitate the shar

Updated on:February 26,2024

Brain changes following traumatic brain injury share similarities with Alzheimer's disease

by Jenesse Miller,University of Southern CaliforniaThe image displays a TBI-affected brain’s white matter connectivity as inferred using diffusion tensor imaging and streamline tractography. The

Updated on: May 13,2024

Brain changes following traumatic brain injury share similarities with Alzheimer's disease

by Jenesse Miller,University of Southern CaliforniaThe image displays a TBI-affected brain’s white matter connectivity as inferred using diffusion tensor imaging and streamline tractography. The

Updated on:May 13,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on: September 03,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on:September 03,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on: March 02,2024

Researchers identify new gene mutation that alters Alzheimer's disease risk

by Indiana University School of MedicineGraphical Abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.08.008A study led by experts from Indiana University School of Medicine h

Updated on:March 02,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on: April 25,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on:April 25,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on: April 16,2024

Alzheimer's disease raises the risk of severe COVID-19 and death from this viral disease

by Elton Alisson,FAPESPPatients with dementia and especially Alzheimer’s run a threefold risk of dying as a result of infection by SARS-CoV-2. The risk is six times greater if they are over 80,

Updated on:April 16,2024