New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on: April 18,2024

New insights into the formation of toxic protein clumps in Alzheimer's disease

byForschungszentrum JuelichSmall Aβ oligomers (left: cryo-electron microscopy) are clumps consisting of just a few Aβ molecules. They cluster together to form short, worm-like structures known a

Updated on:April 18,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on: April 25,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on:April 25,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on: April 02,2024

Tau protein changes correlate with Alzheimer's disease dementia stage

by Alice McCarthy,Children's Hospital BostonPET scan of a human brain with Alzheimer's disease. Credit: public domainResearch into Alzheimer's disease has long focused on understandi

Updated on:April 02,2024

Aging reduces the ability of regulatory T cells to enhance myelin regeneration, study finds

byMiguel Hernandez University of ElcheA Diagram explaining the experimental design of in vivo Treg depletion, Treg adoptive transfer and spinal cord demyelination. Representative images of immun

Updated on: March 28,2024

Aging reduces the ability of regulatory T cells to enhance myelin regeneration, study finds

byMiguel Hernandez University of ElcheA Diagram explaining the experimental design of in vivo Treg depletion, Treg adoptive transfer and spinal cord demyelination. Representative images of immun

Updated on:March 28,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on: August 08,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on:August 08,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on: January 12,2024

Scientists reveal structures of neurotransmitter transporter

bySt. Jude Children's Research HospitalCorresponding author Chia-Hsueh Lee, Ph.D., co-first author Shabareesh Pidathala, Ph.D., and co-first author Yaxin Dai, Ph.D. with maps of neurotransmi

Updated on:January 12,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on: January 12,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on:January 12,2024

Cognitive impairment afflicts majority of stroke patients

by Wenche Margrethe Kulmo,Norwegian University of Science and TechnologyCredit: Marcus Aurelius from PexelsParalysis and difficulty speaking are well-known problems following a stroke. Establish

Updated on: February 18,2024

Cognitive impairment afflicts majority of stroke patients

by Wenche Margrethe Kulmo,Norwegian University of Science and TechnologyCredit: Marcus Aurelius from PexelsParalysis and difficulty speaking are well-known problems following a stroke. Establish

Updated on:February 18,2024

Researchers find some evidence of link between stress, Alzheimer's disease

by University of FloridaTodd Golde, M.D., Ph.D., director of the UF Center for Translational Research in Neurodegenerative Disease and a professor in the UF College of Medicine's department o

Updated on: February 26,2024

Researchers find some evidence of link between stress, Alzheimer's disease

by University of FloridaTodd Golde, M.D., Ph.D., director of the UF Center for Translational Research in Neurodegenerative Disease and a professor in the UF College of Medicine's department o

Updated on:February 26,2024

Dopamine treatment found to alleviate symptoms in Alzheimer's disease

byRIKENImmunostaining of Aβ (Green) detected by N1D antibody from frontal cortices of 12-month-old AppNL-F; DAT-Cre mice infected with or without the viral vectors AAV8-hSyn-DIO-mCherry and AAV8

Updated on: August 08,2024

Dopamine treatment found to alleviate symptoms in Alzheimer's disease

byRIKENImmunostaining of Aβ (Green) detected by N1D antibody from frontal cortices of 12-month-old AppNL-F; DAT-Cre mice infected with or without the viral vectors AAV8-hSyn-DIO-mCherry and AAV8

Updated on:August 08,2024

Reducing early brain inflammation could slow Alzheimer's progression

by Experimental BiologyThis fluorescent photomicrograph shows astrocytes (green) and neurons (pink) in the dentate gyrus of rat hippocampus. Credit: Giorgia Menegoni, Sapienza, University of RomeIn a

Updated on: June 20,2024

Reducing early brain inflammation could slow Alzheimer's progression

by Experimental BiologyThis fluorescent photomicrograph shows astrocytes (green) and neurons (pink) in the dentate gyrus of rat hippocampus. Credit: Giorgia Menegoni, Sapienza, University of RomeIn a

Updated on:June 20,2024

'Didn't understand my suffering': When children get migraines

Credit: Unsplash/CC0 Public DomainMaiwenn Colleaux was 14 when she first started getting migraines, and they immediately turned her life upside down."When I had an attack, I could no longer go ou

Updated on: January 21,2024

'Didn't understand my suffering': When children get migraines

Credit: Unsplash/CC0 Public DomainMaiwenn Colleaux was 14 when she first started getting migraines, and they immediately turned her life upside down."When I had an attack, I could no longer go ou

Updated on:January 21,2024