Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on: December 18,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on:December 18,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024

Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease

by American Academy of NeurologyCredit: CC0 Public DomainThe drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study p

Updated on: June 01,2024

Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease

by American Academy of NeurologyCredit: CC0 Public DomainThe drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study p

Updated on:June 01,2024

Towards better management of disinhibition in frontotemporal dementia

by Marie Simon,Paris Brain InstituteReconstruction of a waiting room for the ECOCAPTURE study. Credit: FrontLab, Paris Brain InstituteDisinhibition is one of the main symptoms of the behavioral

Updated on: June 05,2024

Towards better management of disinhibition in frontotemporal dementia

by Marie Simon,Paris Brain InstituteReconstruction of a waiting room for the ECOCAPTURE study. Credit: FrontLab, Paris Brain InstituteDisinhibition is one of the main symptoms of the behavioral

Updated on:June 05,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on: December 11,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on:December 11,2024

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on: January 12,2024

Anxiety may be contagious, mouse study suggests

bySociety for NeuroscienceCredit: CC0 Public DomainSevere instances of stress experienced early in life (ELS) are a risk factor for developing neuropsychiatric diseases, such as anxiety, later i

Updated on:January 12,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on: June 18,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on:June 18,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on: February 26,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on:February 26,2024

Disorders of consciousness: Increasing awareness of advances in brain injury medicine

by IOS PressCredit: Pixabay/CC0 Public DomainEmerging trends and new developments in the care and management of patients with disorders of consciousness (DoC) are increasingly focused on a multid

Updated on: March 19,2024

Disorders of consciousness: Increasing awareness of advances in brain injury medicine

by IOS PressCredit: Pixabay/CC0 Public DomainEmerging trends and new developments in the care and management of patients with disorders of consciousness (DoC) are increasingly focused on a multid

Updated on:March 19,2024

How do we decide what to look at next? A computational model has the answer

byTechnical University of BerlinObject-based scanpath simulation in dynamic scenes. Credit: The image is derived from a frame of the field03 video of the VidCom dataset (Permission to Publish Co

Updated on: January 11,2024

How do we decide what to look at next? A computational model has the answer

byTechnical University of BerlinObject-based scanpath simulation in dynamic scenes. Credit: The image is derived from a frame of the field03 video of the VidCom dataset (Permission to Publish Co

Updated on:January 11,2024

Researchers identify key genes in the development of the primate brain

by Bill Hathaway,Yale UniversityRegionalization of macaque telencephalon. Single-cell transcriptomics of prenatal macaque telencephalic regions distinguished subtypes spanning development. The t

Updated on: January 12,2024

Researchers identify key genes in the development of the primate brain

by Bill Hathaway,Yale UniversityRegionalization of macaque telencephalon. Single-cell transcriptomics of prenatal macaque telencephalic regions distinguished subtypes spanning development. The t

Updated on:January 12,2024