Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on: April 18,2024

Improved cellular recycling could benefit patients with neurodegenerative conditions

byThe Hospital for Sick ChildrenNon-functioning parts of the cell like damaged peroxisomes (pictured in yellow) are not recycled properly. On the right is an image from the Kim-Bandsma lab showi

Updated on:April 18,2024

ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on: June 14,2024

ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on:June 14,2024

Breaking stereotype: Brain models are not one-size-fits-all

by Yale UniversityCredit: Pixabay/CC0 Public DomainMachine learning has helped scientists understand how the brain gives rise to complex human characteristics, uncovering patterns of brain activi

Updated on: February 18,2024

Breaking stereotype: Brain models are not one-size-fits-all

by Yale UniversityCredit: Pixabay/CC0 Public DomainMachine learning has helped scientists understand how the brain gives rise to complex human characteristics, uncovering patterns of brain activi

Updated on:February 18,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on: December 11,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on:December 11,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on: June 18,2024

Memory may be preserved in condition with brain changes similar to Alzheimer's disease

by American Academy of NeurologyCredit: Unsplash/CC0 Public DomainPrimary progressive aphasia is a rare neurodegenerative condition characterized by prominent language problems that worsen over t

Updated on:June 18,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on: April 25,2024

Australia unprepared to move future Alzheimer's treatment into rapid clinical use

by RAND CorporationCredit: CC0 Public DomainAs in other countries, the Australian health care system has limited capacity to rapidly move a future treatment for Alzheimer's disease from appro

Updated on:April 25,2024

Marriage is linked to reduced dementia risk

by Alzheimer's Research UKResearchers from University College London have found that people who are single or widowed are at a greater risk of dementia than people who are married. The resear

Updated on: March 07,2024

Marriage is linked to reduced dementia risk

by Alzheimer's Research UKResearchers from University College London have found that people who are single or widowed are at a greater risk of dementia than people who are married. The resear

Updated on:March 07,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on: December 18,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on:December 18,2024

Towards better management of disinhibition in frontotemporal dementia

by Marie Simon,Paris Brain InstituteReconstruction of a waiting room for the ECOCAPTURE study. Credit: FrontLab, Paris Brain InstituteDisinhibition is one of the main symptoms of the behavioral

Updated on: June 05,2024

Towards better management of disinhibition in frontotemporal dementia

by Marie Simon,Paris Brain InstituteReconstruction of a waiting room for the ECOCAPTURE study. Credit: FrontLab, Paris Brain InstituteDisinhibition is one of the main symptoms of the behavioral

Updated on:June 05,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on: April 29,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on:April 29,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on: February 26,2024

New drug candidate ameliorates Alzheimer's and other brain diseases

by Ludwig Maximilian University of MunichCredit: Jens WagnerProfessor Armin Giese from the Center for Neuropathology and Prion Research at the LMU Munich and researchers at the Max Planck Institu

Updated on:February 26,2024