Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on: June 18,2024

Could disease pathogens be the dark matter behind Alzheimer's disease?

by Richard Harth,Arizona State UniversityCould viruses, bacteria or other infectious pathogens play a role in the onset or progression of Alzheimer's disease? A new Viewpoint article discuss

Updated on:June 18,2024

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on: July 01,2024

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on:July 01,2024

Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia

by St. Michael's HospitalCredit: CC0 Public DomainFor patients with dementia who have symptoms of aggression and agitation, interventions such as outdoor activities, massage and touch therapy

Updated on: June 01,2024

Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia

by St. Michael's HospitalCredit: CC0 Public DomainFor patients with dementia who have symptoms of aggression and agitation, interventions such as outdoor activities, massage and touch therapy

Updated on:June 01,2024

Gut could sound early warning alarm for motor neuron disease

by University of AberdeenCredit: Pixabay/CC0 Public DomainThe same proteins thought to contribute to motor neuron disease can be found in the gut many years before any brain symptoms occur, a new

Updated on: February 03,2024

Gut could sound early warning alarm for motor neuron disease

by University of AberdeenCredit: Pixabay/CC0 Public DomainThe same proteins thought to contribute to motor neuron disease can be found in the gut many years before any brain symptoms occur, a new

Updated on:February 03,2024

Pandemic adds to challenge of caring for loved one with dementia

by Amy NortonBefore the COVID-19 outbreak, Annette Adams-Brown's 87-year-old mother was an avid follower of TV news. Now Adams-Brown has to channel-surf for a less stressful pastime.Her mother, Be

Updated on: May 13,2024

Pandemic adds to challenge of caring for loved one with dementia

by Amy NortonBefore the COVID-19 outbreak, Annette Adams-Brown's 87-year-old mother was an avid follower of TV news. Now Adams-Brown has to channel-surf for a less stressful pastime.Her mother, Be

Updated on:May 13,2024

Most caregivers of people with dementia are family members, and they need help

by Alan Stevens, Carole White, Marcia G. Ory And Sandhya Sanghi,The ConversationCredit: Kindel Media from PexelsFamily care of an older adult has emerged as an essential element of the U.S. heal

Updated on: May 13,2024

Most caregivers of people with dementia are family members, and they need help

by Alan Stevens, Carole White, Marcia G. Ory And Sandhya Sanghi,The ConversationCredit: Kindel Media from PexelsFamily care of an older adult has emerged as an essential element of the U.S. heal

Updated on:May 13,2024

Molecular alterations in neuronal trophic regulation in Alzheimer's pathology

by Jason Clement,McGill UniversityCredit: Unsplash/CC0 Public DomainFor decades researchers have known that Alzheimer's disease (AD) causes the atrophy of a system of neurons and synapses hi

Updated on: April 02,2024

Molecular alterations in neuronal trophic regulation in Alzheimer's pathology

by Jason Clement,McGill UniversityCredit: Unsplash/CC0 Public DomainFor decades researchers have known that Alzheimer's disease (AD) causes the atrophy of a system of neurons and synapses hi

Updated on:April 02,2024

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on: March 26,2024

Aduhelm: Will Medicare cover the controversial Alzheimer's drug?

by Dennis Thompson(HealthDay)—Following a months-long and unprecedented review, Medicare officials expect to announce within the next couple of weeks whether the program will cover the controversial A

Updated on:March 26,2024

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on: April 10,2024

Alzheimer's disease: Sex affects tau accumulation in the brain

by Society of Nuclear Medicine and Molecular ImagingSex Modulates the ApoE ε4 Effect on 18F-AV-1451 Tau PET. Credit: Paranjpe M, Liu M, Paranjpe I, et al.The strongest genetic risk factor for Alzheime

Updated on:April 10,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on: August 08,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on:August 08,2024

Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease

by American Academy of NeurologyCredit: CC0 Public DomainThe drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study p

Updated on: June 01,2024

Erectile dysfunction drugs may be linked to reduced risk of Alzheimer's disease

by American Academy of NeurologyCredit: CC0 Public DomainThe drugs used to treat erectile dysfunction may also be associated with a reduced risk of Alzheimer's disease, according to a study p

Updated on:June 01,2024