A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on: April 16,2024

A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on:April 16,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on: August 08,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on:August 08,2024

Reducing early brain inflammation could slow Alzheimer's progression

by Experimental BiologyThis fluorescent photomicrograph shows astrocytes (green) and neurons (pink) in the dentate gyrus of rat hippocampus. Credit: Giorgia Menegoni, Sapienza, University of RomeIn a

Updated on: June 20,2024

Reducing early brain inflammation could slow Alzheimer's progression

by Experimental BiologyThis fluorescent photomicrograph shows astrocytes (green) and neurons (pink) in the dentate gyrus of rat hippocampus. Credit: Giorgia Menegoni, Sapienza, University of RomeIn a

Updated on:June 20,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on: June 01,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on:June 01,2024

IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on: April 16,2024

IL-21 protein a key part of immune response to central nervous system infections

by Zachary Sweger,Pennsylvania State UniversityT cells infiltrating brains of MuPyV-infected mice captured in the Lukacher lab. Credit: Penn StateResearchers at Penn State College of Medicine no

Updated on:April 16,2024

Activity is important for your brain and for the prevention of Alzheimer's, suggests neurovascular study

by University of Copenhagen"By staying active, we are able to maintain a healthy vascular system so that the blood vessels stay flexible and retain the ability to drive forward the cerebrosp

Updated on: March 02,2024

Activity is important for your brain and for the prevention of Alzheimer's, suggests neurovascular study

by University of Copenhagen"By staying active, we are able to maintain a healthy vascular system so that the blood vessels stay flexible and retain the ability to drive forward the cerebrosp

Updated on:March 02,2024

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on: July 31,2024

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on:July 31,2024

Neuroscientists uncover important thinning mechanism that affects how the brain matures in adolescence

byUniversity of MontrealCredit: CC0 Public DomainWhat determines how a teenager's brain is structured and how it evolves? In a scientific first, researchers led by Université de Montréal neu

Updated on: January 12,2024

Neuroscientists uncover important thinning mechanism that affects how the brain matures in adolescence

byUniversity of MontrealCredit: CC0 Public DomainWhat determines how a teenager's brain is structured and how it evolves? In a scientific first, researchers led by Université de Montréal neu

Updated on:January 12,2024

How gut bacteria influence the effects of cocaine in mice

by Cell PressThis photo represents Cuesta et al.'s demonstration that cocaine exposure increases norepinephrine in the gut facilitating γ-Proteobacteria colonization. This gut microbiota shif

Updated on: February 03,2024

How gut bacteria influence the effects of cocaine in mice

by Cell PressThis photo represents Cuesta et al.'s demonstration that cocaine exposure increases norepinephrine in the gut facilitating γ-Proteobacteria colonization. This gut microbiota shif

Updated on:February 03,2024

Researchers find some evidence of link between stress, Alzheimer's disease

by University of FloridaTodd Golde, M.D., Ph.D., director of the UF Center for Translational Research in Neurodegenerative Disease and a professor in the UF College of Medicine's department o

Updated on: February 26,2024

Researchers find some evidence of link between stress, Alzheimer's disease

by University of FloridaTodd Golde, M.D., Ph.D., director of the UF Center for Translational Research in Neurodegenerative Disease and a professor in the UF College of Medicine's department o

Updated on:February 26,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on: March 30,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on:March 30,2024

Early biomarker found for degenerative neurologic disease

by Society of Nuclear Medicine and Molecular ImagingPI-2620 binding expressed as distribution volume ratios from multilinear reference tissue modeling 2. Axial and sagittal slices from averaged groups

Updated on: June 01,2024

Early biomarker found for degenerative neurologic disease

by Society of Nuclear Medicine and Molecular ImagingPI-2620 binding expressed as distribution volume ratios from multilinear reference tissue modeling 2. Axial and sagittal slices from averaged groups

Updated on:June 01,2024