How retrotransposons control the brain

by John Hewitt , Medical XpressCredit: WikipediaAround half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in va

Updated on: June 01,2024

How retrotransposons control the brain

by John Hewitt , Medical XpressCredit: WikipediaAround half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in va

Updated on:June 01,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on: March 30,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on:March 30,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on: May 05,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on:May 05,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on: February 26,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on:February 26,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on: January 12,2024

Unexpected link found between 2 schizophrenia risk proteins

by Emily Caldwell,The Ohio State UniversityBehavioral alterations in MAP6−/−and Kv3.1−/−mice. Adult (3–6 months old) WT B6 (black bars), MAP6−/−(red bars), and Kv3.1−/−(g

Updated on:January 12,2024

Genetics study finds ancestral background can affect Alzheimer's disease risk

by University of Miami Leonard M. Miller School of MedicineThe difference in APOE expression between African and European local ancestry carriers. University of Miami Leonard M. Miller School of

Updated on: March 09,2024

Genetics study finds ancestral background can affect Alzheimer's disease risk

by University of Miami Leonard M. Miller School of MedicineThe difference in APOE expression between African and European local ancestry carriers. University of Miami Leonard M. Miller School of

Updated on:March 09,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on: June 24,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on:June 24,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on: March 26,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on:March 26,2024

People with dementia encouraged to hang up the keys

by Kirsten O'leary,University of QueenslandResearchers have created a program to help people with dementia to hang up their car keys. Credit: University of QueenslandWhen people with dementi

Updated on: May 06,2024

People with dementia encouraged to hang up the keys

by Kirsten O'leary,University of QueenslandResearchers have created a program to help people with dementia to hang up their car keys. Credit: University of QueenslandWhen people with dementi

Updated on:May 06,2024

Black people less likely to receive dementia-related medications

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainBlack people are receiving medications for dementia less often than white people, according to a preliminary study released today,

Updated on: June 07,2024

Black people less likely to receive dementia-related medications

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainBlack people are receiving medications for dementia less often than white people, according to a preliminary study released today,

Updated on:June 07,2024