Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on: April 08,2024

Alzheimer's disease risk gene APOE4 impairs function of brain immune cells

by University of Eastern FinlandThe induced pluripotent stem cell (iPSC) -derived microglia demonstrate that apolipoprotein E4 (APOE4) has a profound impact on several functions of human brain im

Updated on:April 08,2024

Blood test for Alzheimer's disease predicts future cognitive decline in healthy people

by Brigham and Women's HospitalCredit: CC0 Public DomainToday, a clinician can order a blood test to check a patient's cholesterol or hemoglobin A1c levels—biomarkers that help predict an

Updated on: April 08,2024

Blood test for Alzheimer's disease predicts future cognitive decline in healthy people

by Brigham and Women's HospitalCredit: CC0 Public DomainToday, a clinician can order a blood test to check a patient's cholesterol or hemoglobin A1c levels—biomarkers that help predict an

Updated on:April 08,2024

Brain stimulation shows promise in treating drug addiction

by Marla Broadfoot,Mayo ClinicCredit: Public DomainToday, neurostimulation is used to treat avariety of human disorders, including Parkinson's disease, tremor, obsessive-compulsive dis

Updated on: March 19,2024

Brain stimulation shows promise in treating drug addiction

by Marla Broadfoot,Mayo ClinicCredit: Public DomainToday, neurostimulation is used to treat avariety of human disorders, including Parkinson's disease, tremor, obsessive-compulsive dis

Updated on:March 19,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Researchers define seizure burden, developmental outcomes for STXBP1-related disorders

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) found that seizure patterns and response to treatment st

Updated on: June 24,2024

Researchers define seizure burden, developmental outcomes for STXBP1-related disorders

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) found that seizure patterns and response to treatment st

Updated on:June 24,2024

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on: February 28,2024

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on:February 28,2024

Research reveals exercise brain boost can last for years

byUniversity of QueenslandCredit: Pixabay/CC0 Public DomainA longitudinal study by University of Queensland researchers has found high-intensity interval exercise improves brain function in olde

Updated on: July 11,2024

Research reveals exercise brain boost can last for years

byUniversity of QueenslandCredit: Pixabay/CC0 Public DomainA longitudinal study by University of Queensland researchers has found high-intensity interval exercise improves brain function in olde

Updated on:July 11,2024

Lightweight, head-mounted microscope unveils brain oxygenation in freely moving mice

by TranSpreadPhotoacoustic fiberscope for cerebral imaging in the freely moving-state. Credit:Light: Science & Applications(2024). DOI: 10.1038/s41377-023-01348-3The brain consumes app

Updated on: April 06,2024

Lightweight, head-mounted microscope unveils brain oxygenation in freely moving mice

by TranSpreadPhotoacoustic fiberscope for cerebral imaging in the freely moving-state. Credit:Light: Science & Applications(2024). DOI: 10.1038/s41377-023-01348-3The brain consumes app

Updated on:April 06,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on: March 02,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on:March 02,2024

Professor discusses what's new in concussion treatment and management

by Laura Bailey,University of MichiganCredit: Unsplash/CC0 Public DomainThere have been significant changes in the last few years in how concussions are identified and treated. Steven Broglio, d

Updated on: March 30,2024

Professor discusses what's new in concussion treatment and management

by Laura Bailey,University of MichiganCredit: Unsplash/CC0 Public DomainThere have been significant changes in the last few years in how concussions are identified and treated. Steven Broglio, d

Updated on:March 30,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on: March 07,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on:March 07,2024

Study reveals brain's role in starting meals through GABA, dopamine

by Taylor Barnes,Baylor College of MedicineCredit:Metabolism(2024). DOI: 10.1016/j.metabol.2024.156099When you are feeling hungry, the brain takes the necessary steps toward consumin

Updated on: January 15,2025

Study reveals brain's role in starting meals through GABA, dopamine

by Taylor Barnes,Baylor College of MedicineCredit:Metabolism(2024). DOI: 10.1016/j.metabol.2024.156099When you are feeling hungry, the brain takes the necessary steps toward consumin

Updated on:January 15,2025