Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on: April 02,2024

Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on:April 02,2024

High biological age may increase the risk of dementia and stroke

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainPeople who have a higher biological age than their actual chronological age have a significantly increased risk of stroke and dementia, e

Updated on: February 24,2024

High biological age may increase the risk of dementia and stroke

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainPeople who have a higher biological age than their actual chronological age have a significantly increased risk of stroke and dementia, e

Updated on:February 24,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on: April 29,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on:April 29,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on: April 29,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on:April 29,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on: March 07,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on:March 07,2024

Depression best treated by nonpharmacological approaches in people living with dementia

by University of New South WalesCredit: Pixabay/CC0 Public DomainResearch led by UNSW Sydney's Center for Healthy Brain Aging (CHeBA) has confirmed treating symptoms of depression is most eff

Updated on: May 06,2024

Depression best treated by nonpharmacological approaches in people living with dementia

by University of New South WalesCredit: Pixabay/CC0 Public DomainResearch led by UNSW Sydney's Center for Healthy Brain Aging (CHeBA) has confirmed treating symptoms of depression is most eff

Updated on:May 06,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on: March 02,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on:March 02,2024

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on: February 05,2024

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on:February 05,2024

Racial differences in Alzheimer's disease unveiled

by Washington University School of MedicineCredit: CC0 Public DomainAfrican-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why becaus

Updated on: April 08,2024

Racial differences in Alzheimer's disease unveiled

by Washington University School of MedicineCredit: CC0 Public DomainAfrican-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why becaus

Updated on:April 08,2024

How brain circuits switch between different behaviors

by Weizmann Institute of ScienceSet-up and behavioral task. a, The experimental set-up. Bats flew in pairs and alternated between two behavioral modes: solo (left) and cross-over (right). b, Exam

Updated on: February 21,2024

How brain circuits switch between different behaviors

by Weizmann Institute of ScienceSet-up and behavioral task. a, The experimental set-up. Bats flew in pairs and alternated between two behavioral modes: solo (left) and cross-over (right). b, Exam

Updated on:February 21,2024