Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Researchers investigate the aging brain and peripheral vascular dysfunction

by Impact Journals LLCCerebrovascular dysfunction is an underlying feature of most major types of dementia. Credit: 2024 Wahl and Clayton.A new review paper waspublishedinAging

Updated on: June 15,2024

Researchers investigate the aging brain and peripheral vascular dysfunction

by Impact Journals LLCCerebrovascular dysfunction is an underlying feature of most major types of dementia. Credit: 2024 Wahl and Clayton.A new review paper waspublishedinAging

Updated on:June 15,2024

Form of B12 deficiency in cerebral spinal fluid found to negatively affect the central nervous system

by Bob Yirka , Medical XpressA patient with an unsual MRI and neurologic deficits eluded typical diagnostic tests.Credit: John PluvinageA large team of doctors and medical researchers with diver

Updated on: July 05,2024

Form of B12 deficiency in cerebral spinal fluid found to negatively affect the central nervous system

by Bob Yirka , Medical XpressA patient with an unsual MRI and neurologic deficits eluded typical diagnostic tests.Credit: John PluvinageA large team of doctors and medical researchers with diver

Updated on:July 05,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on: July 01,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on:July 01,2024

How retrotransposons control the brain

by John Hewitt , Medical XpressCredit: WikipediaAround half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in va

Updated on: June 01,2024

How retrotransposons control the brain

by John Hewitt , Medical XpressCredit: WikipediaAround half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in va

Updated on:June 01,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on: March 07,2024

Lifestyle changes prevent cognitive decline even in genetically susceptible individuals

by University of Eastern FinlandEnhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, accor

Updated on:March 07,2024

Novel algorithm improves intracranial EEG accuracy to enhance future patient care

byUniversity of Minnesota Medical SchoolThe ABCD Algorithm. (A) Example raw log-power spectra from 152 channels during a single recording session. (B) Example, mean log-power spectrum and second

Updated on: September 06,2024

Novel algorithm improves intracranial EEG accuracy to enhance future patient care

byUniversity of Minnesota Medical SchoolThe ABCD Algorithm. (A) Example raw log-power spectra from 152 channels during a single recording session. (B) Example, mean log-power spectrum and second

Updated on:September 06,2024

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on: February 28,2024

Eli Lilly changes outcome goals in Alzheimer's drug study

by Linda A. JohnsonEli Lilly said Tuesday that it's changed the outcome goals for a late-stage patient study of its closely watched experimental drug for Alzheimer's disease, solanezumab.The E

Updated on:February 28,2024

Genetics study finds ancestral background can affect Alzheimer's disease risk

by University of Miami Leonard M. Miller School of MedicineThe difference in APOE expression between African and European local ancestry carriers. University of Miami Leonard M. Miller School of

Updated on: March 09,2024

Genetics study finds ancestral background can affect Alzheimer's disease risk

by University of Miami Leonard M. Miller School of MedicineThe difference in APOE expression between African and European local ancestry carriers. University of Miami Leonard M. Miller School of

Updated on:March 09,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on: June 24,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on:June 24,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on: June 18,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on:June 18,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on: March 26,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on:March 26,2024