Researchers investigate the aging brain and peripheral vascular dysfunction

by Impact Journals LLCCerebrovascular dysfunction is an underlying feature of most major types of dementia. Credit: 2024 Wahl and Clayton.A new review paper waspublishedinAging

Updated on: June 15,2024

Researchers investigate the aging brain and peripheral vascular dysfunction

by Impact Journals LLCCerebrovascular dysfunction is an underlying feature of most major types of dementia. Credit: 2024 Wahl and Clayton.A new review paper waspublishedinAging

Updated on:June 15,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on: March 02,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on:March 02,2024

Making long-term memories requires DNA damage, researchers discover

by Albert Einstein College of MedicineFragments released from the nuclei of neurons undergoing DNA damage during learning: DNA (large white dot at center right), histones (purple), and transcript

Updated on: March 30,2024

Making long-term memories requires DNA damage, researchers discover

by Albert Einstein College of MedicineFragments released from the nuclei of neurons undergoing DNA damage during learning: DNA (large white dot at center right), histones (purple), and transcript

Updated on:March 30,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on: March 30,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on:March 30,2024

Massive genome study informs the biology of reading and language

by Max Planck SocietyCredit: Pixabay/CC0 Public DomainWhat is the biological basis of our uniquely human capacity to speak, read and write? A genome-wide analysis of five reading- and language-ba

Updated on: February 18,2024

Massive genome study informs the biology of reading and language

by Max Planck SocietyCredit: Pixabay/CC0 Public DomainWhat is the biological basis of our uniquely human capacity to speak, read and write? A genome-wide analysis of five reading- and language-ba

Updated on:February 18,2024

How brain circuits switch between different behaviors

by Weizmann Institute of ScienceSet-up and behavioral task. a, The experimental set-up. Bats flew in pairs and alternated between two behavioral modes: solo (left) and cross-over (right). b, Exam

Updated on: February 21,2024

How brain circuits switch between different behaviors

by Weizmann Institute of ScienceSet-up and behavioral task. a, The experimental set-up. Bats flew in pairs and alternated between two behavioral modes: solo (left) and cross-over (right). b, Exam

Updated on:February 21,2024

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on: February 21,2024

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on:February 21,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on: April 28,2024

Decoding spontaneous thoughts from the brain via machine learning

by Institute for Basic ScienceFigure 1. Predictive modeling analysis pipelineFirst, the data was independently segmented into quintiles (5 levels) for self-relevance and valence based on particip

Updated on:April 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Dopamine treatment found to alleviate symptoms in Alzheimer's disease

byRIKENImmunostaining of Aβ (Green) detected by N1D antibody from frontal cortices of 12-month-old AppNL-F; DAT-Cre mice infected with or without the viral vectors AAV8-hSyn-DIO-mCherry and AAV8

Updated on: August 08,2024

Dopamine treatment found to alleviate symptoms in Alzheimer's disease

byRIKENImmunostaining of Aβ (Green) detected by N1D antibody from frontal cortices of 12-month-old AppNL-F; DAT-Cre mice infected with or without the viral vectors AAV8-hSyn-DIO-mCherry and AAV8

Updated on:August 08,2024

Radiologists could soon be using AI to detect brain tumors

byOxford University PressCredit: Anna Shvets from PexelsA paper titled "Deep Learning and Transfer Learning for Brain Tumor Detection and Classification" published inBiology Meth

Updated on: November 23,2024

Radiologists could soon be using AI to detect brain tumors

byOxford University PressCredit: Anna Shvets from PexelsA paper titled "Deep Learning and Transfer Learning for Brain Tumor Detection and Classification" published inBiology Meth

Updated on:November 23,2024