Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Metabolism linked to brain health

by University of South AustraliaCredit: MART PRODUCTION from PexelsEvery three seconds, someone in the world is diagnosed with dementia. And while there is no known cure, changes in the brain can

Updated on: April 01,2024

Metabolism linked to brain health

by University of South AustraliaCredit: MART PRODUCTION from PexelsEvery three seconds, someone in the world is diagnosed with dementia. And while there is no known cure, changes in the brain can

Updated on:April 01,2024

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on: March 28,2024

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on:March 28,2024

Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on: March 30,2024

Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on:March 30,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on: May 20,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on:May 20,2024

ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on: June 14,2024

ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on:June 14,2024

Research suggests myelin fatty acid metabolism could serve as an energy reserve for the central nervous system

by Ingrid Fadelli , Medical XpressElectron microscopy image of optic nerve myelin. Credit: Wiebke Moebius, MPI Goettingen.The brains of mammals expend a significant amount of energy in the form of ade

Updated on: October 18,2024

Research suggests myelin fatty acid metabolism could serve as an energy reserve for the central nervous system

by Ingrid Fadelli , Medical XpressElectron microscopy image of optic nerve myelin. Credit: Wiebke Moebius, MPI Goettingen.The brains of mammals expend a significant amount of energy in the form of ade

Updated on:October 18,2024

AI stroke brain scan readings found to be twice as accurate as current method

by Samantha Rey,Imperial College LondonMethods overview. Credit:npj Digital Medicine(2024). DOI: 10.1038/s41746-024-01325-zNew AI software can read the brain scans of patients who ha

Updated on: December 17,2024

AI stroke brain scan readings found to be twice as accurate as current method

by Samantha Rey,Imperial College LondonMethods overview. Credit:npj Digital Medicine(2024). DOI: 10.1038/s41746-024-01325-zNew AI software can read the brain scans of patients who ha

Updated on:December 17,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on: January 12,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on:January 12,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on: April 20,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on:April 20,2024

Molecular alterations in neuronal trophic regulation in Alzheimer's pathology

by Jason Clement,McGill UniversityCredit: Unsplash/CC0 Public DomainFor decades researchers have known that Alzheimer's disease (AD) causes the atrophy of a system of neurons and synapses hi

Updated on: April 02,2024

Molecular alterations in neuronal trophic regulation in Alzheimer's pathology

by Jason Clement,McGill UniversityCredit: Unsplash/CC0 Public DomainFor decades researchers have known that Alzheimer's disease (AD) causes the atrophy of a system of neurons and synapses hi

Updated on:April 02,2024