Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on: March 19,2024

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on:March 19,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Neuroscientists discover interactions between brain waves and nerve cells during human memory processes

by University Hospital of BonnIllustration of the hypothesis that human associative object–location memory is linked to the coactivity of object cells and place cells during hippocampal ripples. We pr

Updated on: March 13,2024

Neuroscientists discover interactions between brain waves and nerve cells during human memory processes

by University Hospital of BonnIllustration of the hypothesis that human associative object–location memory is linked to the coactivity of object cells and place cells during hippocampal ripples. We pr

Updated on:March 13,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on: February 03,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on:February 03,2024

Alzheimer's genes might show effects in your 20s

by Alan MozesEvery college student misplaces keys or forgets an appointment from time to time. Usually it's no big deal. But a new study warns that when young people with a family history of Alzhe

Updated on: April 18,2024

Alzheimer's genes might show effects in your 20s

by Alan MozesEvery college student misplaces keys or forgets an appointment from time to time. Usually it's no big deal. But a new study warns that when young people with a family history of Alzhe

Updated on:April 18,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on: March 28,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on:March 28,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on: June 01,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on:June 01,2024

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on: February 05,2024

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on:February 05,2024

Hidden financial dimensions affect people with cognitive decline and their care partners, report says

by The Gerontological Society of AmericaCredit: CC0 Public DomainIn planning for older adulthood, many people both fear and consistently underestimate the risk of Alzheimer's disease and related d

Updated on: April 29,2024

Hidden financial dimensions affect people with cognitive decline and their care partners, report says

by The Gerontological Society of AmericaCredit: CC0 Public DomainIn planning for older adulthood, many people both fear and consistently underestimate the risk of Alzheimer's disease and related d

Updated on:April 29,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on: July 05,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on:July 05,2024

Call it Mighty Mouse: Breakthrough leaps Alzheimer's research hurdle

by University of California, IrvineThe reserchers, led by Mathew Blurton-Jones, associate professor of neurobiology & behavior, said the breakthrough also holds promise for investigating many

Updated on: May 06,2024

Call it Mighty Mouse: Breakthrough leaps Alzheimer's research hurdle

by University of California, IrvineThe reserchers, led by Mathew Blurton-Jones, associate professor of neurobiology & behavior, said the breakthrough also holds promise for investigating many

Updated on:May 06,2024