Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on: March 30,2024

Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on:March 30,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on: May 05,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on:May 05,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on: May 20,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on:May 20,2024

App promises to improve pain management for dementia patients

by Katie Willis,University of AlbertaCredit: CC0 Public DomainUniversity of Alberta computing scientists are developing an app to help health-care staff assess and manage pain in patients with d

Updated on: March 19,2024

App promises to improve pain management for dementia patients

by Katie Willis,University of AlbertaCredit: CC0 Public DomainUniversity of Alberta computing scientists are developing an app to help health-care staff assess and manage pain in patients with d

Updated on:March 19,2024

Alzheimer's and an unusual molecular chaperone

by University of KonstanzPET scan of a human brain with Alzheimer's disease. Credit: public domainAmong the hallmarks of Alzheimer's disease are the Alzheimer fibrils, deposits of the tau

Updated on: April 20,2024

Alzheimer's and an unusual molecular chaperone

by University of KonstanzPET scan of a human brain with Alzheimer's disease. Credit: public domainAmong the hallmarks of Alzheimer's disease are the Alzheimer fibrils, deposits of the tau

Updated on:April 20,2024

Resveratrol appears to restore blood-brain barrier integrity in Alzheimer's disease

by Georgetown University Medical CenterSkeletal formula of trans-resveratrol. Image: WikipediaResveratrol, given to Alzheimer's patients, appears to restore the integrity of the blood-brain b

Updated on: March 09,2024

Resveratrol appears to restore blood-brain barrier integrity in Alzheimer's disease

by Georgetown University Medical CenterSkeletal formula of trans-resveratrol. Image: WikipediaResveratrol, given to Alzheimer's patients, appears to restore the integrity of the blood-brain b

Updated on:March 09,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Dementia leading cause of death in September

by Alzheimer's Research UKCredit: CC0 Public DomainThe Office for National Statistics (ONS) has today (23 October) revealed "dementia and Alzheimer's disease" were the leading c

Updated on: May 11,2024

Dementia leading cause of death in September

by Alzheimer's Research UKCredit: CC0 Public DomainThe Office for National Statistics (ONS) has today (23 October) revealed "dementia and Alzheimer's disease" were the leading c

Updated on:May 11,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Cholesterol may be key to new therapies for Alzheimer's disease, diabetes

by University of Arizona Health SciencesCredit: Unsplash/CC0 Public DomainA University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2

Updated on: May 20,2024

Cholesterol may be key to new therapies for Alzheimer's disease, diabetes

by University of Arizona Health SciencesCredit: Unsplash/CC0 Public DomainA University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2

Updated on:May 20,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on: April 29,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on:April 29,2024

Study discovers a 'brain thesaurus' that lets neurons derive meaning from spoken words

by Brandon Chase,Massachusetts General HospitalCredit: CC0 Public DomainUsing a novel technology for obtaining recordings from single neurons, a team of investigators at Massachusetts General Ho

Updated on: July 05,2024

Study discovers a 'brain thesaurus' that lets neurons derive meaning from spoken words

by Brandon Chase,Massachusetts General HospitalCredit: CC0 Public DomainUsing a novel technology for obtaining recordings from single neurons, a team of investigators at Massachusetts General Ho

Updated on:July 05,2024