Alzheimer's disease: Viagra is seen as a potential treatment, but the research shows contradictory findings

by Ian Maidment and Hayley Gorton,The ConversationCredit: CC0 Public DomainArecent study reportedthat sildenafil, sold under the brand name Viagra, and other medicines from the same

Updated on: March 22,2024

Alzheimer's disease: Viagra is seen as a potential treatment, but the research shows contradictory findings

by Ian Maidment and Hayley Gorton,The ConversationCredit: CC0 Public DomainArecent study reportedthat sildenafil, sold under the brand name Viagra, and other medicines from the same

Updated on:March 22,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on: April 29,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on:April 29,2024

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on: April 18,2024

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on:April 18,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Research reveals exercise brain boost can last for years

byUniversity of QueenslandCredit: Pixabay/CC0 Public DomainA longitudinal study by University of Queensland researchers has found high-intensity interval exercise improves brain function in olde

Updated on: July 11,2024

Research reveals exercise brain boost can last for years

byUniversity of QueenslandCredit: Pixabay/CC0 Public DomainA longitudinal study by University of Queensland researchers has found high-intensity interval exercise improves brain function in olde

Updated on:July 11,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on: March 25,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on:March 25,2024

Potential new treatment for Alzheimer's disease would be relatively cheap

by RIKENNeprilysin (red) and Aβ (green) levels in the hippocampus of Alzheimer's disease model mice. Top: control. Bottom: after being fed diazoxide. After diazoxide treatment, neprilysin lev

Updated on: April 07,2024

Potential new treatment for Alzheimer's disease would be relatively cheap

by RIKENNeprilysin (red) and Aβ (green) levels in the hippocampus of Alzheimer's disease model mice. Top: control. Bottom: after being fed diazoxide. After diazoxide treatment, neprilysin lev

Updated on:April 07,2024

Making long-term memories requires DNA damage, researchers discover

by Albert Einstein College of MedicineFragments released from the nuclei of neurons undergoing DNA damage during learning: DNA (large white dot at center right), histones (purple), and transcript

Updated on: March 30,2024

Making long-term memories requires DNA damage, researchers discover

by Albert Einstein College of MedicineFragments released from the nuclei of neurons undergoing DNA damage during learning: DNA (large white dot at center right), histones (purple), and transcript

Updated on:March 30,2024

New Alzheimer risk gene discovered

by Oxford University PressCredit: CC0 Public DomainA new paper in theJournal of Neuropathology & Experimental Neurologyfinds a gene that may help explain a large part of the genet

Updated on: June 01,2024

New Alzheimer risk gene discovered

by Oxford University PressCredit: CC0 Public DomainA new paper in theJournal of Neuropathology & Experimental Neurologyfinds a gene that may help explain a large part of the genet

Updated on:June 01,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on: February 27,2024

Lipid-based diets effectively combat Alzheimer's disease in mouse model

by Bentham Science PublishersResearchers have devised several lipid-based diets aimed at slowing down progression and relieving symptoms of Alzheimer's disease. Credit: Janickova et al, Bentham Sc

Updated on:February 27,2024

How the brain filters out sounds

by Goethe University Frankfurt am MainSearching for fruit at night: Seba's short-tailed bat. Credit: Julio Hechavarria / Goethe University Frankfurt, GermanyBats are renowned for their echolo

Updated on: February 21,2024

How the brain filters out sounds

by Goethe University Frankfurt am MainSearching for fruit at night: Seba's short-tailed bat. Credit: Julio Hechavarria / Goethe University Frankfurt, GermanyBats are renowned for their echolo

Updated on:February 21,2024

Brain stimulation improves motor skill learning at older age

by Ecole Polytechnique Federale de LausanneA visual summary of the study. Credit: Pablo Maceira-Elvira (EPFL)Even though we don't think about it, every movement we make in our daily life esse

Updated on: February 21,2024

Brain stimulation improves motor skill learning at older age

by Ecole Polytechnique Federale de LausanneA visual summary of the study. Credit: Pablo Maceira-Elvira (EPFL)Even though we don't think about it, every movement we make in our daily life esse

Updated on:February 21,2024