Hidden financial dimensions affect people with cognitive decline and their care partners, report says

by The Gerontological Society of AmericaCredit: CC0 Public DomainIn planning for older adulthood, many people both fear and consistently underestimate the risk of Alzheimer's disease and related d

Updated on: April 29,2024

Hidden financial dimensions affect people with cognitive decline and their care partners, report says

by The Gerontological Society of AmericaCredit: CC0 Public DomainIn planning for older adulthood, many people both fear and consistently underestimate the risk of Alzheimer's disease and related d

Updated on:April 29,2024

Form of B12 deficiency in cerebral spinal fluid found to negatively affect the central nervous system

by Bob Yirka , Medical XpressA patient with an unsual MRI and neurologic deficits eluded typical diagnostic tests.Credit: John PluvinageA large team of doctors and medical researchers with diver

Updated on: July 05,2024

Form of B12 deficiency in cerebral spinal fluid found to negatively affect the central nervous system

by Bob Yirka , Medical XpressA patient with an unsual MRI and neurologic deficits eluded typical diagnostic tests.Credit: John PluvinageA large team of doctors and medical researchers with diver

Updated on:July 05,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on: February 26,2024

Down syndrome research untangles therapeutic possibilities for Alzheimer's

by University of California - San DiegoMichael Rafii, M.D., Ph.D., UC San Diego Health. Credit: UC San Diego HealthMore than five million Americans are living with Alzheimer's disease (AD). O

Updated on:February 26,2024

Brain vesicles found to contain selectively packaged, full-length mRNA

by Sanford-Burnham PrebysThis portrait of extracellular vesicles was taken using confocal laser scanning microscopy. The membrane was stained with fluorescent dye. Image titled"Exosome

Updated on: April 28,2024

Brain vesicles found to contain selectively packaged, full-length mRNA

by Sanford-Burnham PrebysThis portrait of extracellular vesicles was taken using confocal laser scanning microscopy. The membrane was stained with fluorescent dye. Image titled"Exosome

Updated on:April 28,2024

Research team identifies new treatment target for Alzheimer's disease

byLancaster UniversityAlzheimer's disease is the leading cause of dementia and disability in old age. Credit: Lancaster UniversityResearchers at the University of Leeds and Lancaster Univers

Updated on: March 28,2024

Research team identifies new treatment target for Alzheimer's disease

byLancaster UniversityAlzheimer's disease is the leading cause of dementia and disability in old age. Credit: Lancaster UniversityResearchers at the University of Leeds and Lancaster Univers

Updated on:March 28,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on: August 08,2024

It is not clear whether new Alzheimer's drugs will make a difference at a population level, say researchers

byUniversity of CambridgeCredit: CC0 Public DomainCambridge researchers have cast doubt on whether new amyloid immunotherapy drugs will have the desired effect of significantly reducing the impa

Updated on:August 08,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on: March 02,2024

Blood vessel breakdown linked with Alzheimer's disease

by Centenary InstituteSGP expression in mouse models of AD. Representative images of SGP expression in APP/PS1 (A) and APP23 (B) compared to wildtype (WT) mice over different stages of plaque dev

Updated on:March 02,2024

Psychotropic meds tied to risk for post-COVID dementia in seniors

Pre-COVID-19 psychotropic medication use is associated with higher risk for incident dementia following hospitalization for COVID-19 (post-COVID dementia) in older adults, according to a study publish

Updated on: July 04,2024

Psychotropic meds tied to risk for post-COVID dementia in seniors

Pre-COVID-19 psychotropic medication use is associated with higher risk for incident dementia following hospitalization for COVID-19 (post-COVID dementia) in older adults, according to a study publish

Updated on:July 04,2024

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on: March 03,2025

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on:March 03,2025

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024