Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on: March 02,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on:March 02,2024

Study indicates possible link between chronic stress and Alzheimer's disease

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainResearchers from Karolinska Institutet have publisheda studyinAlzheimer's Research & Therapythat addresse

Updated on: March 02,2024

Study indicates possible link between chronic stress and Alzheimer's disease

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainResearchers from Karolinska Institutet have publisheda studyinAlzheimer's Research & Therapythat addresse

Updated on:March 02,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on: September 06,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on:September 06,2024

Healthy diet may reduce cognitive decline as people age

by Karolinska InstitutetEating healthier may reduce cognitive decline and diminish the negative impact of an unhealthy diet on memory and thinking abilities in older adults, suggests a new study

Updated on: February 26,2024

Healthy diet may reduce cognitive decline as people age

by Karolinska InstitutetEating healthier may reduce cognitive decline and diminish the negative impact of an unhealthy diet on memory and thinking abilities in older adults, suggests a new study

Updated on:February 26,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on: June 11,2024

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on:June 11,2024

Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on: April 02,2024

Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on:April 02,2024

Alzheimer's drug gets FDA panel's backing, setting the stage for broader use

by Matthew PerroneThis Dec. 21, 2022, image provided by Eisai in January 2023 shows vials and packaging for their medication Leqembi. On Friday, June 9, 2023, health advisers backed the full approval

Updated on: April 16,2024

Alzheimer's drug gets FDA panel's backing, setting the stage for broader use

by Matthew PerroneThis Dec. 21, 2022, image provided by Eisai in January 2023 shows vials and packaging for their medication Leqembi. On Friday, June 9, 2023, health advisers backed the full approval

Updated on:April 16,2024

Electrical stimulation on wrist can sway hand choice and possibly aid rehabilitation

byWaseda UniversitySomatosensory electrical stimulation settings. Anodal electrodes with a 3-cm diameter are attached to the ventral distal end of the forearm on each side, while the cathodal el

Updated on: January 18,2025

Electrical stimulation on wrist can sway hand choice and possibly aid rehabilitation

byWaseda UniversitySomatosensory electrical stimulation settings. Anodal electrodes with a 3-cm diameter are attached to the ventral distal end of the forearm on each side, while the cathodal el

Updated on:January 18,2025

Researchers identify three genes associated with neurodevelopmental disorders

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI171235An international study group led by researchers of

Updated on: June 19,2024

Researchers identify three genes associated with neurodevelopmental disorders

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI171235An international study group led by researchers of

Updated on:June 19,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024