Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on: June 01,2024

Nonprofits, federal government surpass pharma to lead Alzheimer's drug development

by Alzheimer's AssociationPET scan of a human brain with Alzheimer's disease. Credit: public domainTwo articles published online today byAlzheimer's & Dementia: Translational Res

Updated on:June 01,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on: May 05,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on:May 05,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on: May 20,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on:May 20,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on: April 20,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on:April 20,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024

30 years on, are we winning the fight against Alzheimer's?

by Suzanne Leigh, University of CaliforniaA set of 16 brain PET scans, with orange areas representing Alzheimer's progression. Credit: UC San FranciscoUC San Francisco experts say that we have rea

Updated on: March 13,2024

30 years on, are we winning the fight against Alzheimer's?

by Suzanne Leigh, University of CaliforniaA set of 16 brain PET scans, with orange areas representing Alzheimer's progression. Credit: UC San FranciscoUC San Francisco experts say that we have rea

Updated on:March 13,2024

Metabolism linked to brain health

by University of South AustraliaCredit: MART PRODUCTION from PexelsEvery three seconds, someone in the world is diagnosed with dementia. And while there is no known cure, changes in the brain can

Updated on: April 01,2024

Metabolism linked to brain health

by University of South AustraliaCredit: MART PRODUCTION from PexelsEvery three seconds, someone in the world is diagnosed with dementia. And while there is no known cure, changes in the brain can

Updated on:April 01,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Study indicates possible link between chronic stress and Alzheimer's disease

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainResearchers from Karolinska Institutet have publisheda studyinAlzheimer's Research & Therapythat addresse

Updated on: March 02,2024

Study indicates possible link between chronic stress and Alzheimer's disease

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainResearchers from Karolinska Institutet have publisheda studyinAlzheimer's Research & Therapythat addresse

Updated on:March 02,2024

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

by University of QueenslandThe signalling protein Fyn moving and forming clusters in living brain cells - viewed using super-resolution microscopy. Credit: Meunier Lab, University of QueenslandUn

Updated on: May 05,2024

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

by University of QueenslandThe signalling protein Fyn moving and forming clusters in living brain cells - viewed using super-resolution microscopy. Credit: Meunier Lab, University of QueenslandUn

Updated on:May 05,2024

New biomarker for dementia diagnosis

by Flinders UniversityProfessor Arduino Mangoni, Head of Clinical Pharmacology at Flinders University, in his research laboratory in South Australia. Credit: Flinders UniversityMedical researcher

Updated on: May 11,2024

New biomarker for dementia diagnosis

by Flinders UniversityProfessor Arduino Mangoni, Head of Clinical Pharmacology at Flinders University, in his research laboratory in South Australia. Credit: Flinders UniversityMedical researcher

Updated on:May 11,2024