Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

The brain isn't the only place a stroke can occur

by Laura WilliamsonSudden, painless loss of vision. Burning back pain. Achy legs. Incontinence.People might not recognize these as signs of astroke, because some are not the symptoms of a stroke

Updated on: February 21,2024

The brain isn't the only place a stroke can occur

by Laura WilliamsonSudden, painless loss of vision. Burning back pain. Achy legs. Incontinence.People might not recognize these as signs of astroke, because some are not the symptoms of a stroke

Updated on:February 21,2024

Molecular alterations in neuronal trophic regulation in Alzheimer's pathology

by Jason Clement,McGill UniversityCredit: Unsplash/CC0 Public DomainFor decades researchers have known that Alzheimer's disease (AD) causes the atrophy of a system of neurons and synapses hi

Updated on: April 02,2024

Molecular alterations in neuronal trophic regulation in Alzheimer's pathology

by Jason Clement,McGill UniversityCredit: Unsplash/CC0 Public DomainFor decades researchers have known that Alzheimer's disease (AD) causes the atrophy of a system of neurons and synapses hi

Updated on:April 02,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on: May 05,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on:May 05,2024

Testing memory over four weeks could predict Alzheimer's disease risk

by University of BristolCredit: CC0 Public DomainNew research suggests testing people's memory over four weeks could identify who is at higher risk of developing Alzheimer's disease befor

Updated on: May 05,2024

Testing memory over four weeks could predict Alzheimer's disease risk

by University of BristolCredit: CC0 Public DomainNew research suggests testing people's memory over four weeks could identify who is at higher risk of developing Alzheimer's disease befor

Updated on:May 05,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on: June 24,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on:June 24,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on: March 26,2024

Cortexyme publishes data on P. gingivalis ability to infect neurons

by IOS PressP. gingivalisbacteria (arrows), after invading a neuron, causes damage to the cellular infrastructure and synapses. Credit: Cortexyme, Inc.Cortexyme, Inc., a clinical stage biop

Updated on:March 26,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on: March 30,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on:March 30,2024

How much does dementia risk increase after traumatic brain injury?

by Public Library of ScienceThe WHO has predicted that TBI will become a leading cause of death and long-term illness during the next ten years. Already one per cent of the population in the United St

Updated on: May 13,2024

How much does dementia risk increase after traumatic brain injury?

by Public Library of ScienceThe WHO has predicted that TBI will become a leading cause of death and long-term illness during the next ten years. Already one per cent of the population in the United St

Updated on:May 13,2024

Alzheimer's trial screening data links high amyloid levels with early stage disease

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainThe first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer&#39

Updated on: April 20,2024

Alzheimer's trial screening data links high amyloid levels with early stage disease

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainThe first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer&#39

Updated on:April 20,2024

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on: March 03,2025

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on:March 03,2025