Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024

On Nutrition: Food for thoughts

by Barbara IntermillCredit: Unsplash/CC0 Public DomainI forgot that June was Brain Health Awareness Month. And then I stumbled over several interesting research articles that say it's never to lat

Updated on: April 01,2024

On Nutrition: Food for thoughts

by Barbara IntermillCredit: Unsplash/CC0 Public DomainI forgot that June was Brain Health Awareness Month. And then I stumbled over several interesting research articles that say it's never to lat

Updated on:April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Researchers develop new brain network modeling tools to advance Alzheimer's disease research

by Indiana University School of MedicineCredit: CC0 Public DomainIndiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously dev

Updated on: February 24,2024

Researchers develop new brain network modeling tools to advance Alzheimer's disease research

by Indiana University School of MedicineCredit: CC0 Public DomainIndiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously dev

Updated on:February 24,2024

How does the brain keep calm? Insight into brain stability and the key role of NMDA receptors

byTel-Aviv UniversityGraphical abstract. Credit:Neuron(2024). DOI: 10.1016/j.neuron.2024.10.014Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor

Updated on: November 28,2024

How does the brain keep calm? Insight into brain stability and the key role of NMDA receptors

byTel-Aviv UniversityGraphical abstract. Credit:Neuron(2024). DOI: 10.1016/j.neuron.2024.10.014Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor

Updated on:November 28,2024

ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on: June 14,2024

ALS and dementia attacked by an RNA-hunting compound that recruits cell's own virus fighter

by The Scripps Research InstituteTo study the effectiveness of their compounds, the scientists directed cells from patients with ALS to become stem cells and then specialize into nerve cells. Cre

Updated on:June 14,2024

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on: February 05,2024

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on:February 05,2024

Dementia leading cause of death in September

by Alzheimer's Research UKCredit: CC0 Public DomainThe Office for National Statistics (ONS) has today (23 October) revealed "dementia and Alzheimer's disease" were the leading c

Updated on: May 11,2024

Dementia leading cause of death in September

by Alzheimer's Research UKCredit: CC0 Public DomainThe Office for National Statistics (ONS) has today (23 October) revealed "dementia and Alzheimer's disease" were the leading c

Updated on:May 11,2024

Alzheimer's may strike women and men in different ways

by Steven Reinberg Healthday Reporter(HealthDay)—The ravages of Alzheimer's may strike later in women than men, but once it takes hold women tend to deteriorate far faster than men, according to a

Updated on: April 25,2024

Alzheimer's may strike women and men in different ways

by Steven Reinberg Healthday Reporter(HealthDay)—The ravages of Alzheimer's may strike later in women than men, but once it takes hold women tend to deteriorate far faster than men, according to a

Updated on:April 25,2024

Brain mapping technique reveals insights into brain's higher functions

byUniversity of BirminghamHigher-order brain mapping: schematic of the approach and applications. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54472-yA new way of mapp

Updated on: December 17,2024

Brain mapping technique reveals insights into brain's higher functions

byUniversity of BirminghamHigher-order brain mapping: schematic of the approach and applications. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54472-yA new way of mapp

Updated on:December 17,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024