Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on: March 02,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on:March 02,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Poor sleep among African Americans associated with diminished cognitive function

by RAND CorporationCredit: Unsplash/CC0 Public DomainMore fragmented sleep and longer periods of wakefulness after bedtime among a group of low-income African American adults were associated with

Updated on: June 01,2024

Poor sleep among African Americans associated with diminished cognitive function

by RAND CorporationCredit: Unsplash/CC0 Public DomainMore fragmented sleep and longer periods of wakefulness after bedtime among a group of low-income African American adults were associated with

Updated on:June 01,2024

Electrical stimulation on wrist can sway hand choice and possibly aid rehabilitation

byWaseda UniversitySomatosensory electrical stimulation settings. Anodal electrodes with a 3-cm diameter are attached to the ventral distal end of the forearm on each side, while the cathodal el

Updated on: January 18,2025

Electrical stimulation on wrist can sway hand choice and possibly aid rehabilitation

byWaseda UniversitySomatosensory electrical stimulation settings. Anodal electrodes with a 3-cm diameter are attached to the ventral distal end of the forearm on each side, while the cathodal el

Updated on:January 18,2025

New study reveals limited public understanding of dementia globally

by Trinity College DublinBelieving that dementia is a normal part of aging is the most common misconception about dementia, according to a new study conducted by researchers at Trinity College Du

Updated on: February 26,2024

New study reveals limited public understanding of dementia globally

by Trinity College DublinBelieving that dementia is a normal part of aging is the most common misconception about dementia, according to a new study conducted by researchers at Trinity College Du

Updated on:February 26,2024

Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on: April 02,2024

Alzheimer's: Protective immune cells active decades before symptom onset

by German Center for Neurodegenerative DiseasesCredit: Pixabay/CC0 Public DomainIn individuals with a genetic predisposition to Alzheimer's disease, the immune cells of the brain—the "mi

Updated on:April 02,2024

Researchers identify three genes associated with neurodevelopmental disorders

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI171235An international study group led by researchers of

Updated on: June 19,2024

Researchers identify three genes associated with neurodevelopmental disorders

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI171235An international study group led by researchers of

Updated on:June 19,2024

New research explains how brain blood vessels are formed

by Université libre de BruxellesMmp25 as a regulator of brain-specific angiogenesis.a, The TC genotype in mosaic sprouts during brain vascular invasion (36 hpf,n = 23 sprouts) and tru

Updated on: April 06,2024

New research explains how brain blood vessels are formed

by Université libre de BruxellesMmp25 as a regulator of brain-specific angiogenesis.a, The TC genotype in mosaic sprouts during brain vascular invasion (36 hpf,n = 23 sprouts) and tru

Updated on:April 06,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on: December 18,2024

Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits

byNiigata UniversityL-arginine inhibits the aggregation of polyglutamine proteins in neuronal cells. Credit: Niigata UniversityA team has conducted a trial on the efficacy and safety of L-argini

Updated on:December 18,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on: May 22,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on:May 22,2024