Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Make this Halloween a safe one for people with dementia

by Cara MurezHalloween is often frightening for loved ones who have dementia, but there are ways to keep it safe and not scary."Halloween can be very challenging and stressful for someone with de

Updated on: February 24,2024

Make this Halloween a safe one for people with dementia

by Cara MurezHalloween is often frightening for loved ones who have dementia, but there are ways to keep it safe and not scary."Halloween can be very challenging and stressful for someone with de

Updated on:February 24,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on: May 20,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on:May 20,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on: April 20,2024

Diagnosis of Alzheimer's and related dementias reduces social activity

by Rutgers UniversityCredit: Pixabay/CC0 Public DomainDespite the belief that early diagnosis of Alzheimer's disease and other dementias is crucial, a new Rutgers study found that the diagnos

Updated on:April 20,2024

'Care Chair' helps detect patients' movements, mental state

by Joe Mccune,Missouri University of Science and TechnologyDebraj De, a postdoctoral fellow at Missouri S&T, and S&T professor Sajal Das developed a chair sensor device that can detect a

Updated on: March 09,2024

'Care Chair' helps detect patients' movements, mental state

by Joe Mccune,Missouri University of Science and TechnologyDebraj De, a postdoctoral fellow at Missouri S&T, and S&T professor Sajal Das developed a chair sensor device that can detect a

Updated on:March 09,2024

Magnetic resonance imaging shows brain inflammation in vivo for the first time

by Spanish National Research Council (CSIC)Researchers from the UMH-CSIC Neurosciences Institute have developed an innovative strategy that allows imaging of microglial and astrocyte activation in the

Updated on: February 05,2024

Magnetic resonance imaging shows brain inflammation in vivo for the first time

by Spanish National Research Council (CSIC)Researchers from the UMH-CSIC Neurosciences Institute have developed an innovative strategy that allows imaging of microglial and astrocyte activation in the

Updated on:February 05,2024

Study finds high prevalence of hidden brain changes in people with heart disease

byGeorge Institute for Global HealthCredit: Pixabay/CC0 Public DomainA new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of str

Updated on: March 28,2024

Study finds high prevalence of hidden brain changes in people with heart disease

byGeorge Institute for Global HealthCredit: Pixabay/CC0 Public DomainA new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of str

Updated on:March 28,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on: March 30,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on:March 30,2024

Case study showcases effectiveness of multimodality approaches for diagnosing hydrocephalus

by Beijing Institute of Technology Press Co., LtdThis case demonstrates the efficacy of using multimodality approaches for iNPH diagnosis, which saves the patient time and clinical costs, worthy of fu

Updated on: September 05,2024

Case study showcases effectiveness of multimodality approaches for diagnosing hydrocephalus

by Beijing Institute of Technology Press Co., LtdThis case demonstrates the efficacy of using multimodality approaches for iNPH diagnosis, which saves the patient time and clinical costs, worthy of fu

Updated on:September 05,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on: September 06,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on:September 06,2024