Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on: March 30,2024

Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on:March 30,2024

Neuroscientists discover interactions between brain waves and nerve cells during human memory processes

by University Hospital of BonnIllustration of the hypothesis that human associative object–location memory is linked to the coactivity of object cells and place cells during hippocampal ripples. We pr

Updated on: March 13,2024

Neuroscientists discover interactions between brain waves and nerve cells during human memory processes

by University Hospital of BonnIllustration of the hypothesis that human associative object–location memory is linked to the coactivity of object cells and place cells during hippocampal ripples. We pr

Updated on:March 13,2024

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on: February 05,2024

Beyond the brain: A link between hearing loss and autism spectrum disorder

by Josef Blaszkiewicz,Medical University of South CarolinaExpression of the MEF2C protein (green) in the nuclei of neuronal cells (stained with a neuronal marker protein in red) in the inner ear

Updated on:February 05,2024

Early signs of Alzheimer's disease identified

by University of AberdeenCredit: University of AberdeenResearchers from the University of Aberdeen have detected key changes in the brains of people with Alzheimer's disease.The study confirm

Updated on: April 08,2024

Early signs of Alzheimer's disease identified

by University of AberdeenCredit: University of AberdeenResearchers from the University of Aberdeen have detected key changes in the brains of people with Alzheimer's disease.The study confirm

Updated on:April 08,2024

Alzheimer 'tau' protein far surpasses amyloid in predicting toll on brain tissue

by University of California, San FranciscoPET scan of a human brain with Alzheimer's disease. Credit: public domainBrain imaging of pathological tau-protein "tangles" reliably predi

Updated on: April 02,2024

Alzheimer 'tau' protein far surpasses amyloid in predicting toll on brain tissue

by University of California, San FranciscoPET scan of a human brain with Alzheimer's disease. Credit: public domainBrain imaging of pathological tau-protein "tangles" reliably predi

Updated on:April 02,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on: March 25,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on:March 25,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on: March 07,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on:March 07,2024

Scientists compete to make best predictions about pertussis vaccine

by La Jolla Institute for ImmunologyGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100731Scientists love a challenge. Or a friendly competition. Now

Updated on: March 19,2024

Scientists compete to make best predictions about pertussis vaccine

by La Jolla Institute for ImmunologyGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100731Scientists love a challenge. Or a friendly competition. Now

Updated on:March 19,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on: May 08,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on:May 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024