Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Brain mechanism teaches mice to avoid bullies: Findings may offer insight into human social disorders

byNYU Langone HealthCredit: Martha Sexton/public domainLike humans, mice live in complex social groups, fight over territory and mates, and learn when it is safer to avoid certain opponents. Aft

Updated on: March 13,2024

Brain mechanism teaches mice to avoid bullies: Findings may offer insight into human social disorders

byNYU Langone HealthCredit: Martha Sexton/public domainLike humans, mice live in complex social groups, fight over territory and mates, and learn when it is safer to avoid certain opponents. Aft

Updated on:March 13,2024

Pathway deep in the brain makes it resilient after injury

by Sarah Williams,Gladstone InstitutesA new study led by Gladstone researchers suggests that targeting a protein in the thalamus could prevent the long-term damage that follows traumatic brain i

Updated on: February 21,2024

Pathway deep in the brain makes it resilient after injury

by Sarah Williams,Gladstone InstitutesA new study led by Gladstone researchers suggests that targeting a protein in the thalamus could prevent the long-term damage that follows traumatic brain i

Updated on:February 21,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on: November 11,2024

FDA approves Miplyffa for treatment of Niemann-Pick disease, type C

by Lori SolomonThe U.S. Food and Drug Administration has approved Zevra Therapeutics' Miplyffa (arimoclomol), an oral medication for the treatment of Niemann-Pick disease, type C (NPC).Miplyffa, i

Updated on:November 11,2024

Omega-3 levels affect whether B vitamins can slow brain's decline

by University of OxfordWhile research has already established that B vitamin supplements can help slow mental decline in older people with memory problems, an international team have now found th

Updated on: February 27,2024

Omega-3 levels affect whether B vitamins can slow brain's decline

by University of OxfordWhile research has already established that B vitamin supplements can help slow mental decline in older people with memory problems, an international team have now found th

Updated on:February 27,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on: March 13,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on:March 13,2024

How a common food ingredient can take a wrong turn, leading to arthritis

by Mark Harden,CU Anschutz Medical CampusGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI167671A University of Colorado Department of Medicine fac

Updated on: March 19,2024

How a common food ingredient can take a wrong turn, leading to arthritis

by Mark Harden,CU Anschutz Medical CampusGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI167671A University of Colorado Department of Medicine fac

Updated on:March 19,2024

'Curved' walking and a depth camera: New tool detects early cognitive decline

by Florida Atlantic UniversityMahmoud Seifallahi (seated) and Behnaz Ghoraani, Ph.D., reviewing walking performance using a depth camera, which can detect and track 25 joints of body movement. Cr

Updated on: March 19,2024

'Curved' walking and a depth camera: New tool detects early cognitive decline

by Florida Atlantic UniversityMahmoud Seifallahi (seated) and Behnaz Ghoraani, Ph.D., reviewing walking performance using a depth camera, which can detect and track 25 joints of body movement. Cr

Updated on:March 19,2024

Closed-eye imaging can track wakefulness, awareness and pain in unresponsive conditions

byTel-Aviv UniversityPupillary light reflex (PLR) assessment in open-eye and closed-eye conditions. Credit:Communications Medicine(2024). DOI: 10.1038/s43856-024-00572-1A new technol

Updated on: September 23,2024

Closed-eye imaging can track wakefulness, awareness and pain in unresponsive conditions

byTel-Aviv UniversityPupillary light reflex (PLR) assessment in open-eye and closed-eye conditions. Credit:Communications Medicine(2024). DOI: 10.1038/s43856-024-00572-1A new technol

Updated on:September 23,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on: February 03,2024

Blood levels of common antiepileptic drugs drop during pregnancy, causing breakthrough seizures

by University of PittsburghCredit: Unsplash/CC0 Public DomainBlood levels of many commonly used antiepileptic drugs drop dramatically with the onset of pregnancy, report researchers from the Univ

Updated on:February 03,2024

Brain activity differentiates between types of social influence

by Public Library of ScienceDistinct role of dACC in human-human and human-AI interactions. Credit: Bahador Bahrami (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Researchers led by Ali Mahmood

Updated on: February 21,2024

Brain activity differentiates between types of social influence

by Public Library of ScienceDistinct role of dACC in human-human and human-AI interactions. Credit: Bahador Bahrami (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Researchers led by Ali Mahmood

Updated on:February 21,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on: March 28,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on:March 28,2024