Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Pilot study shows promise for remote cognitive rehabilitation for multiple sclerosis patients

by Kessler FoundationCredit: Anna Shvets from PexelsA pilot study shows promise for a new treatment option for individuals with memory impairments caused by multiple sclerosis (MS). Thearticle,

Updated on: July 08,2024

Pilot study shows promise for remote cognitive rehabilitation for multiple sclerosis patients

by Kessler FoundationCredit: Anna Shvets from PexelsA pilot study shows promise for a new treatment option for individuals with memory impairments caused by multiple sclerosis (MS). Thearticle,

Updated on:July 08,2024

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on: March 03,2025

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on:March 03,2025

Understanding genetic risk could save sight and predict multiple sclerosis earlier in young people

byUniversity of ExeterCredit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start ef

Updated on: April 22,2024

Understanding genetic risk could save sight and predict multiple sclerosis earlier in young people

byUniversity of ExeterCredit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start ef

Updated on:April 22,2024

Brain activity differentiates between types of social influence

by Public Library of ScienceDistinct role of dACC in human-human and human-AI interactions. Credit: Bahador Bahrami (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Researchers led by Ali Mahmood

Updated on: February 21,2024

Brain activity differentiates between types of social influence

by Public Library of ScienceDistinct role of dACC in human-human and human-AI interactions. Credit: Bahador Bahrami (CC-BY 4.0, creativecommons.org/licenses/by/4.0/)Researchers led by Ali Mahmood

Updated on:February 21,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on: January 12,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on:January 12,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on: May 05,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on:May 05,2024

Alzheimer's may strike women and men in different ways

by Steven Reinberg Healthday Reporter(HealthDay)—The ravages of Alzheimer's may strike later in women than men, but once it takes hold women tend to deteriorate far faster than men, according to a

Updated on: April 25,2024

Alzheimer's may strike women and men in different ways

by Steven Reinberg Healthday Reporter(HealthDay)—The ravages of Alzheimer's may strike later in women than men, but once it takes hold women tend to deteriorate far faster than men, according to a

Updated on:April 25,2024

30 years on, are we winning the fight against Alzheimer's?

by Suzanne Leigh, University of CaliforniaA set of 16 brain PET scans, with orange areas representing Alzheimer's progression. Credit: UC San FranciscoUC San Francisco experts say that we have rea

Updated on: March 13,2024

30 years on, are we winning the fight against Alzheimer's?

by Suzanne Leigh, University of CaliforniaA set of 16 brain PET scans, with orange areas representing Alzheimer's progression. Credit: UC San FranciscoUC San Francisco experts say that we have rea

Updated on:March 13,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on: March 02,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on:March 02,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024