Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Lithium shows promise in treating autism-related symptoms in mouse study

byInstitute for Basic ScienceLithium restored microcephaly, abnormal synaptic function, and communication issues in mice with Dyrk1a deficiency, a gene associated with autism and Dyrk1a syndrome

Updated on: January 18,2025

Lithium shows promise in treating autism-related symptoms in mouse study

byInstitute for Basic ScienceLithium restored microcephaly, abnormal synaptic function, and communication issues in mice with Dyrk1a deficiency, a gene associated with autism and Dyrk1a syndrome

Updated on:January 18,2025

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on: January 12,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on:January 12,2024

Understanding genetic risk could save sight and predict multiple sclerosis earlier in young people

byUniversity of ExeterCredit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start ef

Updated on: April 22,2024

Understanding genetic risk could save sight and predict multiple sclerosis earlier in young people

byUniversity of ExeterCredit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start ef

Updated on:April 22,2024

How does the brain keep calm? Insight into brain stability and the key role of NMDA receptors

byTel-Aviv UniversityGraphical abstract. Credit:Neuron(2024). DOI: 10.1016/j.neuron.2024.10.014Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor

Updated on: November 28,2024

How does the brain keep calm? Insight into brain stability and the key role of NMDA receptors

byTel-Aviv UniversityGraphical abstract. Credit:Neuron(2024). DOI: 10.1016/j.neuron.2024.10.014Researchers at Tel Aviv University have made a fundamental discovery: the NMDA receptor

Updated on:November 28,2024

Unreliable neurons improve brain functionalities

by Bar-Ilan UniversityCredit: Pixabay/CC0 Public DomainThe brain is composed of millions of billions of neurons that communicate with one another. Each neuron collects its many inputs and transmi

Updated on: February 05,2024

Unreliable neurons improve brain functionalities

by Bar-Ilan UniversityCredit: Pixabay/CC0 Public DomainThe brain is composed of millions of billions of neurons that communicate with one another. Each neuron collects its many inputs and transmi

Updated on:February 05,2024

New biomarker for dementia diagnosis

by Flinders UniversityProfessor Arduino Mangoni, Head of Clinical Pharmacology at Flinders University, in his research laboratory in South Australia. Credit: Flinders UniversityMedical researcher

Updated on: May 11,2024

New biomarker for dementia diagnosis

by Flinders UniversityProfessor Arduino Mangoni, Head of Clinical Pharmacology at Flinders University, in his research laboratory in South Australia. Credit: Flinders UniversityMedical researcher

Updated on:May 11,2024

Decoding the hidden signals of aggression and arousal in the brain

byCalifornia Institute of TechnologyAttractor dynamics in head-fixed mice observing aggression. Credit:Nature(2024). DOI: 10.1038/s41586-024-07915-xA series of three papers from neur

Updated on: November 07,2024

Decoding the hidden signals of aggression and arousal in the brain

byCalifornia Institute of TechnologyAttractor dynamics in head-fixed mice observing aggression. Credit:Nature(2024). DOI: 10.1038/s41586-024-07915-xA series of three papers from neur

Updated on:November 07,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on: April 29,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on:April 29,2024

Alzheimer's may strike women and men in different ways

by Steven Reinberg Healthday Reporter(HealthDay)—The ravages of Alzheimer's may strike later in women than men, but once it takes hold women tend to deteriorate far faster than men, according to a

Updated on: April 25,2024

Alzheimer's may strike women and men in different ways

by Steven Reinberg Healthday Reporter(HealthDay)—The ravages of Alzheimer's may strike later in women than men, but once it takes hold women tend to deteriorate far faster than men, according to a

Updated on:April 25,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on: May 22,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on:May 22,2024