Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on: March 30,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on:March 30,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on: May 20,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on:May 20,2024

How gut neurons communicate with the brain to control thirst

by Lori Dajose,California Institute of TechnologyFig. 1: The vagus nerve responds to visceral osmolality changes. Credit: DOI: 10.1038/s41586-021-04359-5Drinking a glass of water is often suffic

Updated on: February 05,2024

How gut neurons communicate with the brain to control thirst

by Lori Dajose,California Institute of TechnologyFig. 1: The vagus nerve responds to visceral osmolality changes. Credit: DOI: 10.1038/s41586-021-04359-5Drinking a glass of water is often suffic

Updated on:February 05,2024

Dementia study reveals how toxic proteins spread through brain

by University of EdinburghGraphical Abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.04.020Fresh insights into the spread of damaging proteins that build up in the brains of

Updated on: February 03,2024

Dementia study reveals how toxic proteins spread through brain

by University of EdinburghGraphical Abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.04.020Fresh insights into the spread of damaging proteins that build up in the brains of

Updated on:February 03,2024

Extra-large synapses could be a cause of schizophrenia

by RIKENExtra-strong synapses could play an important role in psychiatric disorders such as schizophrenia, a study by RIKEN researchers finds. Credit: Equinox Graphics/Science Photo LibrarySchizo

Updated on: February 03,2024

Extra-large synapses could be a cause of schizophrenia

by RIKENExtra-strong synapses could play an important role in psychiatric disorders such as schizophrenia, a study by RIKEN researchers finds. Credit: Equinox Graphics/Science Photo LibrarySchizo

Updated on:February 03,2024

Three-minute test detects common form of dementia that's hard to diagnose

by Florida Atlantic UniversityJames E. Galvin, M.D., M.P.H., one of the most prominent neuroscientists in the country, and a professor in FAU's Charles E. Schmidt College of Medicine and Chri

Updated on: February 26,2024

Three-minute test detects common form of dementia that's hard to diagnose

by Florida Atlantic UniversityJames E. Galvin, M.D., M.P.H., one of the most prominent neuroscientists in the country, and a professor in FAU's Charles E. Schmidt College of Medicine and Chri

Updated on:February 26,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on: June 18,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on:June 18,2024

Alzheimer's drug gets FDA panel's backing, setting the stage for broader use

by Matthew PerroneThis Dec. 21, 2022, image provided by Eisai in January 2023 shows vials and packaging for their medication Leqembi. On Friday, June 9, 2023, health advisers backed the full approval

Updated on: April 16,2024

Alzheimer's drug gets FDA panel's backing, setting the stage for broader use

by Matthew PerroneThis Dec. 21, 2022, image provided by Eisai in January 2023 shows vials and packaging for their medication Leqembi. On Friday, June 9, 2023, health advisers backed the full approval

Updated on:April 16,2024

Understanding genetic risk could save sight and predict multiple sclerosis earlier in young people

byUniversity of ExeterCredit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start ef

Updated on: April 22,2024

Understanding genetic risk could save sight and predict multiple sclerosis earlier in young people

byUniversity of ExeterCredit: CC0 Public DomainYoung people could be spared from going blind by a new genetic risk tool that could also help diagnose multiple sclerosis (MS) earlier, to start ef

Updated on:April 22,2024

Overlooked proteins may be key to better diagnosis of Alzheimer's

by University of California, San FranciscoCredit: Pixabay/CC0 Public DomainIn a new study of Alzheimer's disease, researchers at UC San Francisco have discovered that a relatively unstudied f

Updated on: April 29,2024

Overlooked proteins may be key to better diagnosis of Alzheimer's

by University of California, San FranciscoCredit: Pixabay/CC0 Public DomainIn a new study of Alzheimer's disease, researchers at UC San Francisco have discovered that a relatively unstudied f

Updated on:April 29,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on: June 24,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on:June 24,2024