Research suggests myelin fatty acid metabolism could serve as an energy reserve for the central nervous system

by Ingrid Fadelli , Medical XpressElectron microscopy image of optic nerve myelin. Credit: Wiebke Moebius, MPI Goettingen.The brains of mammals expend a significant amount of energy in the form of ade

Updated on: October 18,2024

Research suggests myelin fatty acid metabolism could serve as an energy reserve for the central nervous system

by Ingrid Fadelli , Medical XpressElectron microscopy image of optic nerve myelin. Credit: Wiebke Moebius, MPI Goettingen.The brains of mammals expend a significant amount of energy in the form of ade

Updated on:October 18,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on: January 12,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on:January 12,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on: May 05,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on:May 05,2024

Resveratrol appears to restore blood-brain barrier integrity in Alzheimer's disease

by Georgetown University Medical CenterSkeletal formula of trans-resveratrol. Image: WikipediaResveratrol, given to Alzheimer's patients, appears to restore the integrity of the blood-brain b

Updated on: March 09,2024

Resveratrol appears to restore blood-brain barrier integrity in Alzheimer's disease

by Georgetown University Medical CenterSkeletal formula of trans-resveratrol. Image: WikipediaResveratrol, given to Alzheimer's patients, appears to restore the integrity of the blood-brain b

Updated on:March 09,2024

Researchers find unanticipated complexity in aging brain's memory decline

by Stephen Fontenot,University of Texas at DallasSabina Srokova Ph.D. and Dr. Michael Rugg, director of the Center for Vital Longevity. Credit: University of Texas at DallasResearchers from The

Updated on: March 28,2024

Researchers find unanticipated complexity in aging brain's memory decline

by Stephen Fontenot,University of Texas at DallasSabina Srokova Ph.D. and Dr. Michael Rugg, director of the Center for Vital Longevity. Credit: University of Texas at DallasResearchers from The

Updated on:March 28,2024

30 years on, are we winning the fight against Alzheimer's?

by Suzanne Leigh, University of CaliforniaA set of 16 brain PET scans, with orange areas representing Alzheimer's progression. Credit: UC San FranciscoUC San Francisco experts say that we have rea

Updated on: March 13,2024

30 years on, are we winning the fight against Alzheimer's?

by Suzanne Leigh, University of CaliforniaA set of 16 brain PET scans, with orange areas representing Alzheimer's progression. Credit: UC San FranciscoUC San Francisco experts say that we have rea

Updated on:March 13,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on: March 30,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on:March 30,2024

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

by University of QueenslandThe signalling protein Fyn moving and forming clusters in living brain cells - viewed using super-resolution microscopy. Credit: Meunier Lab, University of QueenslandUn

Updated on: May 05,2024

Super-resolution microscopy sheds light on how dementia protein becomes dysfunctional

by University of QueenslandThe signalling protein Fyn moving and forming clusters in living brain cells - viewed using super-resolution microscopy. Credit: Meunier Lab, University of QueenslandUn

Updated on:May 05,2024

Neurons in mouse piriform cortex aid in recurrent circuit development, study finds

by Ingrid Fadelli , Medical XpressEmbryonically active neurons labeled in brain-wide regions, highlighting particularly dense and broad activation in piriform cortex (also known as primary olfactory c

Updated on: October 16,2024

Neurons in mouse piriform cortex aid in recurrent circuit development, study finds

by Ingrid Fadelli , Medical XpressEmbryonically active neurons labeled in brain-wide regions, highlighting particularly dense and broad activation in piriform cortex (also known as primary olfactory c

Updated on:October 16,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on: November 12,2024

Study confirms cognitive deficits in people with the rare disease MOGAD

by Stefan Zorn, Medizinische Hochschule HannoverMean z-scores of neuropsychological tests at baseline (patients <60 years). PASAT, Paced Auditory Serial Addition Task; SDMT, Symbol Digit Modalities

Updated on:November 12,2024