First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Lithium shows promise in treating autism-related symptoms in mouse study

byInstitute for Basic ScienceLithium restored microcephaly, abnormal synaptic function, and communication issues in mice with Dyrk1a deficiency, a gene associated with autism and Dyrk1a syndrome

Updated on: January 18,2025

Lithium shows promise in treating autism-related symptoms in mouse study

byInstitute for Basic ScienceLithium restored microcephaly, abnormal synaptic function, and communication issues in mice with Dyrk1a deficiency, a gene associated with autism and Dyrk1a syndrome

Updated on:January 18,2025

Electrical stimulation on wrist can sway hand choice and possibly aid rehabilitation

byWaseda UniversitySomatosensory electrical stimulation settings. Anodal electrodes with a 3-cm diameter are attached to the ventral distal end of the forearm on each side, while the cathodal el

Updated on: January 18,2025

Electrical stimulation on wrist can sway hand choice and possibly aid rehabilitation

byWaseda UniversitySomatosensory electrical stimulation settings. Anodal electrodes with a 3-cm diameter are attached to the ventral distal end of the forearm on each side, while the cathodal el

Updated on:January 18,2025

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on: April 29,2024

Controversial Alzheimer's drug approval sparks surprising impact

by University of California, IrvineCredit: Pixabay/CC0 Public DomainWhen the U.S. Food and Drug Administration gave controversial accelerated approval to the first Alzheimer's drug in nearly

Updated on:April 29,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on: May 22,2024

Does the Mediterranean diet really decrease your risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainA number of studies have suggested that eating a healthy diet may reduce a person's risk of dementia, but a new study has found that t

Updated on:May 22,2024

Thinning of brain region may signal dementia risk 5–10 years before symptoms

by Will Sansom,University of Texas Health Science Center at San AntonioStrengths of significant association (regression t values) for gray matter thickness in Alzheimer's disease (AD) dement

Updated on: March 13,2024

Thinning of brain region may signal dementia risk 5–10 years before symptoms

by Will Sansom,University of Texas Health Science Center at San AntonioStrengths of significant association (regression t values) for gray matter thickness in Alzheimer's disease (AD) dement

Updated on:March 13,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on: May 05,2024

Gut microbiota, Alzheimer's and the central nervous system

by Justin Jackson , Medical XpressGenetic association between PRSs for Collinsella and APOE rs429358 genotype in the discovery sample. Individuals in the discovery sample were separated by their genot

Updated on:May 05,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on: March 30,2024

Research links age-related inflammation, microglia and Alzheimer's disease

by Nicholas Weiler,Stanford UniversityMyeloid TREM1 expression positively associates with increasing AD pathology. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024-01610-wSt

Updated on:March 30,2024

Cholesterol may be key to new therapies for Alzheimer's disease, diabetes

by University of Arizona Health SciencesCredit: Unsplash/CC0 Public DomainA University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2

Updated on: May 20,2024

Cholesterol may be key to new therapies for Alzheimer's disease, diabetes

by University of Arizona Health SciencesCredit: Unsplash/CC0 Public DomainA University of Arizona Health Sciences researcher examined the role of cholesterol in both Alzheimer's disease and Type 2

Updated on:May 20,2024

What an animated taco reveals about curiosity and patience

byDuke UniversityCredit: Pixabay/CC0 Public DomainCuriosity paradoxically increases people's patience for an answer, while simultaneously making them more eager to hear it, finds a new study

Updated on: January 12,2024

What an animated taco reveals about curiosity and patience

byDuke UniversityCredit: Pixabay/CC0 Public DomainCuriosity paradoxically increases people's patience for an answer, while simultaneously making them more eager to hear it, finds a new study

Updated on:January 12,2024