First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Machine learning can predict rate of memory change

by Alzheimer's Research UKIn new research published today, researchers have created a machine learning algorithm that is able to form two distinct groups of people who have early memory probl

Updated on: March 07,2024

Machine learning can predict rate of memory change

by Alzheimer's Research UKIn new research published today, researchers have created a machine learning algorithm that is able to form two distinct groups of people who have early memory probl

Updated on:March 07,2024

Alzheimer's in one sibling raises risk of shortened lifespan in others

by Leigh Hopper,University of Southern CaliforniaCredit: CC0 Public DomainAn Alzheimer's diagnosis in a sibling raises the risk of a shortened lifespan in other family members—even those wit

Updated on: February 24,2024

Alzheimer's in one sibling raises risk of shortened lifespan in others

by Leigh Hopper,University of Southern CaliforniaCredit: CC0 Public DomainAn Alzheimer's diagnosis in a sibling raises the risk of a shortened lifespan in other family members—even those wit

Updated on:February 24,2024

Dementia and self-harm: Why it's crucial to support patients in first year after diagnosis

by Lachlan Gilbert,University of New South WalesCredit: AI-generated imagePeople diagnosed with dementia are more likely to self-harm within the first six to 12 months after initial diagnosis, h

Updated on: May 08,2024

Dementia and self-harm: Why it's crucial to support patients in first year after diagnosis

by Lachlan Gilbert,University of New South WalesCredit: AI-generated imagePeople diagnosed with dementia are more likely to self-harm within the first six to 12 months after initial diagnosis, h

Updated on:May 08,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on: September 06,2024

Not just a 'bad guy': Researchers discover neuroprotective function of Tau protein

by Rajalaxmi Natarajan,Baylor College of MedicineOverexpression of hTau in glia disrupts LDs and glial cell morphology in response to neuronal ROS. Credit:Nature Neuroscience(2024).

Updated on:September 06,2024

New alteration in the brains of people with Alzheimer's discovered

by Spanish National Research Council (CSIC)Credit: Unsplash/CC0 Public DomainDespite the important advances in research in recent years, the etiopathogenesis of Alzheimer's disease is still not fu

Updated on: April 20,2024

New alteration in the brains of people with Alzheimer's discovered

by Spanish National Research Council (CSIC)Credit: Unsplash/CC0 Public DomainDespite the important advances in research in recent years, the etiopathogenesis of Alzheimer's disease is still not fu

Updated on:April 20,2024

Brain's 'appetite control center' found to be different in people who are overweight or living with obesity

by University of CambridgeCredit: CC0 Public DomainCambridge scientists have shown that the hypothalamus, a key region of the brain involved in controlling appetite, is different in the brains of

Updated on: February 05,2024

Brain's 'appetite control center' found to be different in people who are overweight or living with obesity

by University of CambridgeCredit: CC0 Public DomainCambridge scientists have shown that the hypothalamus, a key region of the brain involved in controlling appetite, is different in the brains of

Updated on:February 05,2024

Decoding the hidden signals of aggression and arousal in the brain

byCalifornia Institute of TechnologyAttractor dynamics in head-fixed mice observing aggression. Credit:Nature(2024). DOI: 10.1038/s41586-024-07915-xA series of three papers from neur

Updated on: November 07,2024

Decoding the hidden signals of aggression and arousal in the brain

byCalifornia Institute of TechnologyAttractor dynamics in head-fixed mice observing aggression. Credit:Nature(2024). DOI: 10.1038/s41586-024-07915-xA series of three papers from neur

Updated on:November 07,2024

Can the healthy brain offer clues to curing Alzheimer's?

by The ConversationImage of brain with regions of the medial temporal lobe colour-coded"Have you cured Alzheimer's disease yet?"This is a common question people ask when they discov

Updated on: June 24,2024

Can the healthy brain offer clues to curing Alzheimer's?

by The ConversationImage of brain with regions of the medial temporal lobe colour-coded"Have you cured Alzheimer's disease yet?"This is a common question people ask when they discov

Updated on:June 24,2024

Researchers develop new brain network modeling tools to advance Alzheimer's disease research

by Indiana University School of MedicineCredit: CC0 Public DomainIndiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously dev

Updated on: February 24,2024

Researchers develop new brain network modeling tools to advance Alzheimer's disease research

by Indiana University School of MedicineCredit: CC0 Public DomainIndiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously dev

Updated on:February 24,2024

Thalamus degeneration found to impact stroke recovery

byBaycrest Centre for Geriatric CareCredit: CC0 Public DomainA recent study by the Baycrest Centre for Geriatric Care reveals that an area of the brain distinct from the stroke lesion may play a

Updated on: December 22,2024

Thalamus degeneration found to impact stroke recovery

byBaycrest Centre for Geriatric CareCredit: CC0 Public DomainA recent study by the Baycrest Centre for Geriatric Care reveals that an area of the brain distinct from the stroke lesion may play a

Updated on:December 22,2024