Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024 3

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024 3

New proteins involved in spinocerebellar ataxia provide insight into selective neuronal vulnerability

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit:Neuron(2022). DOI: 10.1016/j.neuron.2022.11.016Neurodegenerative disorders like Alzheimer's and Parkinson's

Updated on: February 05,2024 10

New proteins involved in spinocerebellar ataxia provide insight into selective neuronal vulnerability

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit:Neuron(2022). DOI: 10.1016/j.neuron.2022.11.016Neurodegenerative disorders like Alzheimer's and Parkinson's

Updated on:February 05,2024 10

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on: October 09,2024 0

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on:October 09,2024 0

BACE-Inhibitor successfully tested in Alzheimer's animal model

by Technical University MunichMarc Aurel Busche at the two-photon microscope, which allows to visualize nerve cells with high temporal and spatial resolution in the intact brain. Credit: Kurt Bau

Updated on: March 19,2024 13

BACE-Inhibitor successfully tested in Alzheimer's animal model

by Technical University MunichMarc Aurel Busche at the two-photon microscope, which allows to visualize nerve cells with high temporal and spatial resolution in the intact brain. Credit: Kurt Bau

Updated on:March 19,2024 13

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on: March 19,2024 16

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on:March 19,2024 16

Elon Musk's brain implant company offers an intriguing glimpse of an internet connecting human minds

by Simon Marvin and Allan McCay,The ConversationCredit: Rice UniversityElon Musk'scompany called Neuralink, launched in 2016, aims toimplant a piece of technologyin people&

Updated on: March 28,2024 0

Elon Musk's brain implant company offers an intriguing glimpse of an internet connecting human minds

by Simon Marvin and Allan McCay,The ConversationCredit: Rice UniversityElon Musk'scompany called Neuralink, launched in 2016, aims toimplant a piece of technologyin people&

Updated on:March 28,2024 0

Dementia: Blood levels could point to early loss of neuronal connections

by Marcus Neitzert,German Center for Neurodegenerative DiseasesGroup comparisons, correlation analyses, and diagnostic performance of serum beta-synuclein and plasma pTau181. (A) Serum beta-synu

Updated on: May 06,2024 19

Dementia: Blood levels could point to early loss of neuronal connections

by Marcus Neitzert,German Center for Neurodegenerative DiseasesGroup comparisons, correlation analyses, and diagnostic performance of serum beta-synuclein and plasma pTau181. (A) Serum beta-synu

Updated on:May 06,2024 19

Reducing early brain inflammation could slow Alzheimer's progression

by Experimental BiologyThis fluorescent photomicrograph shows astrocytes (green) and neurons (pink) in the dentate gyrus of rat hippocampus. Credit: Giorgia Menegoni, Sapienza, University of RomeIn a

Updated on: June 20,2024 6

Reducing early brain inflammation could slow Alzheimer's progression

by Experimental BiologyThis fluorescent photomicrograph shows astrocytes (green) and neurons (pink) in the dentate gyrus of rat hippocampus. Credit: Giorgia Menegoni, Sapienza, University of RomeIn a

Updated on:June 20,2024 6

White matter may aid recovery from spinal cord injuries: Study

by Bill Snyder,Vanderbilt University Medical CenterCredit: CC0 Public DomainInjuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability.

Updated on: August 26,2024 0

White matter may aid recovery from spinal cord injuries: Study

by Bill Snyder,Vanderbilt University Medical CenterCredit: CC0 Public DomainInjuries, infection and inflammatory diseases that damage the spinal cord can lead to intractable pain and disability.

Updated on:August 26,2024 0

Towards better management of disinhibition in frontotemporal dementia

by Marie Simon,Paris Brain InstituteReconstruction of a waiting room for the ECOCAPTURE study. Credit: FrontLab, Paris Brain InstituteDisinhibition is one of the main symptoms of the behavioral

Updated on: June 05,2024 8

Towards better management of disinhibition in frontotemporal dementia

by Marie Simon,Paris Brain InstituteReconstruction of a waiting room for the ECOCAPTURE study. Credit: FrontLab, Paris Brain InstituteDisinhibition is one of the main symptoms of the behavioral

Updated on:June 05,2024 8

Single brain scan can diagnose Alzheimer's disease

by Imperial College LondonPET scan of a human brain with Alzheimer's disease. Credit: public domainThe research uses machine learning technology to look at structural features within the brai

Updated on: May 20,2024 8

Single brain scan can diagnose Alzheimer's disease

by Imperial College LondonPET scan of a human brain with Alzheimer's disease. Credit: public domainThe research uses machine learning technology to look at structural features within the brai

Updated on:May 20,2024 8

Exploring a hidden genetic cause of intellectual disability

byUniversity of the Sunshine CoastMolecular modeling of GTF3C3 variants in the structure of yeast τ131/Tfc4. Credit:Genetics in Medicine(2024). DOI: 10.1016/j.gim.2024.101253A global

Updated on: December 12,2024 0

Exploring a hidden genetic cause of intellectual disability

byUniversity of the Sunshine CoastMolecular modeling of GTF3C3 variants in the structure of yeast τ131/Tfc4. Credit:Genetics in Medicine(2024). DOI: 10.1016/j.gim.2024.101253A global

Updated on:December 12,2024 0