Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on: March 30,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on:March 30,2024

Study finds high prevalence of hidden brain changes in people with heart disease

byGeorge Institute for Global HealthCredit: Pixabay/CC0 Public DomainA new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of str

Updated on: March 28,2024

Study finds high prevalence of hidden brain changes in people with heart disease

byGeorge Institute for Global HealthCredit: Pixabay/CC0 Public DomainA new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of str

Updated on:March 28,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on: July 01,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on:July 01,2024

Metabolism linked to brain health

by University of South AustraliaCredit: MART PRODUCTION from PexelsEvery three seconds, someone in the world is diagnosed with dementia. And while there is no known cure, changes in the brain can

Updated on: April 01,2024

Metabolism linked to brain health

by University of South AustraliaCredit: MART PRODUCTION from PexelsEvery three seconds, someone in the world is diagnosed with dementia. And while there is no known cure, changes in the brain can

Updated on:April 01,2024

High biological age may increase the risk of dementia and stroke

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainPeople who have a higher biological age than their actual chronological age have a significantly increased risk of stroke and dementia, e

Updated on: February 24,2024

High biological age may increase the risk of dementia and stroke

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainPeople who have a higher biological age than their actual chronological age have a significantly increased risk of stroke and dementia, e

Updated on:February 24,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on: May 20,2024

Protein misfolding as a risk marker for Alzheimer's disease

by German Cancer Research CenterCredit: CC0 Public DomainIn symptom-free individuals, the detection of misfolded amyloid-β protein in the blood indicates a considerably higher risk of Alzheimer&#

Updated on:May 20,2024

Genomics- and image-guided subtyping refines characterization of Alzheimer's disease

by Society of Nuclear Medicine and Molecular ImagingRight and left hemisphere brain surface plots showing the strength of the canonical vector, νƙ, for each subtype. Credit: Images created by Fan Yang

Updated on: June 14,2024

Genomics- and image-guided subtyping refines characterization of Alzheimer's disease

by Society of Nuclear Medicine and Molecular ImagingRight and left hemisphere brain surface plots showing the strength of the canonical vector, νƙ, for each subtype. Credit: Images created by Fan Yang

Updated on:June 14,2024

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on: June 11,2024

Imaging of a living brain can help clearly differentiate between two types of dementia

by Champalimaud Centre for the UnknownSPECT images, superimposed on a magnetic resonance atlas, of an axial slice (top row) and a sagittal slice (bottom row) of the human brain, with a quantitative ar

Updated on:June 11,2024

Dementia found to be the dominant risk factor for COVID in elderly care

by University of GothenburgHazard ratios (HR) and 95% Confidence intervals (CI) of the relationship between individual-level factors (age, sex, education, dementia, cardiovascular disease, lung d

Updated on: May 06,2024

Dementia found to be the dominant risk factor for COVID in elderly care

by University of GothenburgHazard ratios (HR) and 95% Confidence intervals (CI) of the relationship between individual-level factors (age, sex, education, dementia, cardiovascular disease, lung d

Updated on:May 06,2024

Uncovering Alzheimer's disease: Researchers examine impact of menopause on cognitive function

by University of MissouriCredit: CC0 Public DomainCharacterized by a buildup of amyloid plaques in the brain, Alzheimer's is an irreversible disease that leads to memory loss and a decrease i

Updated on: July 01,2024

Uncovering Alzheimer's disease: Researchers examine impact of menopause on cognitive function

by University of MissouriCredit: CC0 Public DomainCharacterized by a buildup of amyloid plaques in the brain, Alzheimer's is an irreversible disease that leads to memory loss and a decrease i

Updated on:July 01,2024

Alzheimer's in one sibling raises risk of shortened lifespan in others

by Leigh Hopper,University of Southern CaliforniaCredit: CC0 Public DomainAn Alzheimer's diagnosis in a sibling raises the risk of a shortened lifespan in other family members—even those wit

Updated on: February 24,2024

Alzheimer's in one sibling raises risk of shortened lifespan in others

by Leigh Hopper,University of Southern CaliforniaCredit: CC0 Public DomainAn Alzheimer's diagnosis in a sibling raises the risk of a shortened lifespan in other family members—even those wit

Updated on:February 24,2024