First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Antipsychotic drugs likely overprescribed to homebound patients with dementia, study finds

by WileyCredit: CC0 Public DomainNew research published in theJournal of the American Geriatrics Societyindicates that antipsychotics are likely overprescribed and used inappropriatel

Updated on: March 02,2024

Antipsychotic drugs likely overprescribed to homebound patients with dementia, study finds

by WileyCredit: CC0 Public DomainNew research published in theJournal of the American Geriatrics Societyindicates that antipsychotics are likely overprescribed and used inappropriatel

Updated on:March 02,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on: June 01,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on:June 01,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on: March 13,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on:March 13,2024

New strategy for assessing natural history of leukodystrophies

by Children's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainNatural history studies serve as an important standard in medical research because they analyze demographic, genetic, enviro

Updated on: May 14,2024

New strategy for assessing natural history of leukodystrophies

by Children's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainNatural history studies serve as an important standard in medical research because they analyze demographic, genetic, enviro

Updated on:May 14,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on: September 03,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on:September 03,2024

How our brains learn new athletic skills fast: Investigating electrocortical activity and faster locomotor adaptation

byUniversity of FloridaVisual Overview. Credit:eneuro(2024). DOI: 10.1523/ENEURO.0515-23.2024You join a swing dance class, and at first you're all left feet. But—slowly, eyes glu

Updated on: July 31,2024

How our brains learn new athletic skills fast: Investigating electrocortical activity and faster locomotor adaptation

byUniversity of FloridaVisual Overview. Credit:eneuro(2024). DOI: 10.1523/ENEURO.0515-23.2024You join a swing dance class, and at first you're all left feet. But—slowly, eyes glu

Updated on:July 31,2024

Researchers find preclinical evidence that a nasal immunotherapy may help treat Alzheimer's disease

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainAlzheimer's is a debilitating neurodegenerative and neuroinflammatory disease that is difficult to treat. Most existing th

Updated on: March 02,2024

Researchers find preclinical evidence that a nasal immunotherapy may help treat Alzheimer's disease

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainAlzheimer's is a debilitating neurodegenerative and neuroinflammatory disease that is difficult to treat. Most existing th

Updated on:March 02,2024

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on: March 28,2024

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on:March 28,2024

Experts explore new approach to vaccine trials and pandemic preparedness

byUniversity of CologneExemplary setup of a VACCELERATE APT on vaccines. Credit:Infection(2024). DOI: 10.1007/s15010-024-02347-1An international consortium of experts led by Translat

Updated on: August 01,2024

Experts explore new approach to vaccine trials and pandemic preparedness

byUniversity of CologneExemplary setup of a VACCELERATE APT on vaccines. Credit:Infection(2024). DOI: 10.1007/s15010-024-02347-1An international consortium of experts led by Translat

Updated on:August 01,2024

Alzheimer's and dementia: Understand wandering and how to address it

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWandering and becoming lost is common among people with Alzheimer's disease or other disorders causing dementia. This behavior can happen i

Updated on: April 20,2024

Alzheimer's and dementia: Understand wandering and how to address it

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWandering and becoming lost is common among people with Alzheimer's disease or other disorders causing dementia. This behavior can happen i

Updated on:April 20,2024