Brain pathways that control dopamine release may influence motor control

by Anne Trafton,Massachusetts Institute of TechnologyStriosomal S-D1 and S-D2 populations form parallel pathways to dopamine-containing nigral neurons. Credit:Current Biology(2024).

Updated on: November 07,2024

Brain pathways that control dopamine release may influence motor control

by Anne Trafton,Massachusetts Institute of TechnologyStriosomal S-D1 and S-D2 populations form parallel pathways to dopamine-containing nigral neurons. Credit:Current Biology(2024).

Updated on:November 07,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on: March 28,2024

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on:March 28,2024

'Bugs' in the gut might predict dementia in the brain

by American Heart AssociationCredit: CC0 Public DomainThe makeup of bacteria and other microbes in the gut may have a direct association with dementia risk, according to preliminary research to b

Updated on: May 05,2024

'Bugs' in the gut might predict dementia in the brain

by American Heart AssociationCredit: CC0 Public DomainThe makeup of bacteria and other microbes in the gut may have a direct association with dementia risk, according to preliminary research to b

Updated on:May 05,2024

Alzheimer's and dementia: Understand wandering and how to address it

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWandering and becoming lost is common among people with Alzheimer's disease or other disorders causing dementia. This behavior can happen i

Updated on: April 20,2024

Alzheimer's and dementia: Understand wandering and how to address it

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWandering and becoming lost is common among people with Alzheimer's disease or other disorders causing dementia. This behavior can happen i

Updated on:April 20,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on: April 29,2024

Forget me not: Novel target shows promise in treating Alzheimer's and related dementias

by Matthew Greseth,Medical University of South CarolinaThe cytotoxic tau isomer (cis P-tau; red) is partially colocalized with tau oligomers (green; top) and tau tangles (green; bottom) in Alzhe

Updated on:April 29,2024

Hidden financial dimensions affect people with cognitive decline and their care partners, report says

by The Gerontological Society of AmericaCredit: CC0 Public DomainIn planning for older adulthood, many people both fear and consistently underestimate the risk of Alzheimer's disease and related d

Updated on: April 29,2024

Hidden financial dimensions affect people with cognitive decline and their care partners, report says

by The Gerontological Society of AmericaCredit: CC0 Public DomainIn planning for older adulthood, many people both fear and consistently underestimate the risk of Alzheimer's disease and related d

Updated on:April 29,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on: May 08,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on:May 08,2024

Tiny blood vessels in the brain could be the key in treating vascular dementia

by University of SouthamptonTiny blood vessels in the brain could be the key in treating vascular dementia. Credit: University of SouthamptonResearchers from the University of Southampton are to

Updated on: May 18,2024

Tiny blood vessels in the brain could be the key in treating vascular dementia

by University of SouthamptonTiny blood vessels in the brain could be the key in treating vascular dementia. Credit: University of SouthamptonResearchers from the University of Southampton are to

Updated on:May 18,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on: September 03,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on:September 03,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024