A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on: April 16,2024

A new breakthrough in Alzheimer's disease research: Visualizing reactive astrocyte-neuron interaction

by Institute for Basic ScienceFig. 1. Augmentation of acetate uptake, mediated by MCT1, facilitates Aβ-induced GABA release in reactive astrocyte. A. Blockade effect of MCT1 inhibitor on 14C-acet

Updated on:April 16,2024

Dementia found to be the dominant risk factor for COVID in elderly care

by University of GothenburgHazard ratios (HR) and 95% Confidence intervals (CI) of the relationship between individual-level factors (age, sex, education, dementia, cardiovascular disease, lung d

Updated on: May 06,2024

Dementia found to be the dominant risk factor for COVID in elderly care

by University of GothenburgHazard ratios (HR) and 95% Confidence intervals (CI) of the relationship between individual-level factors (age, sex, education, dementia, cardiovascular disease, lung d

Updated on:May 06,2024

The brain pulsates differently in people suffering from Alzheimer's disease

by University of OuluIn the magnetic resonance image, a healthy brain is higher and a lower one with Alzheimer's disease. Pulsations in the brain appear as red signals at the frequency of the hear

Updated on: April 20,2024

The brain pulsates differently in people suffering from Alzheimer's disease

by University of OuluIn the magnetic resonance image, a healthy brain is higher and a lower one with Alzheimer's disease. Pulsations in the brain appear as red signals at the frequency of the hear

Updated on:April 20,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on: June 24,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on:June 24,2024

Brain organoids reveal in detail the harms of prenatal alcohol exposure

by University of California - San DiegoLab-grown brain organoids help researchers explore early stages of human brain development. Credit: UC San Diego Health SciencesAlcohol consumption during p

Updated on: February 21,2024

Brain organoids reveal in detail the harms of prenatal alcohol exposure

by University of California - San DiegoLab-grown brain organoids help researchers explore early stages of human brain development. Credit: UC San Diego Health SciencesAlcohol consumption during p

Updated on:February 21,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on: July 01,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on:July 01,2024

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on: March 28,2024

Study finds repetitive high concentration capsaicin patch applications beneficial for nerve pain

FEBRUARY 7, 2024byWileyCredit: CC0 Public DomainCapsaicin, derived from hot chili pepper plants, has been used to treat various types of pain, and a high concentration capsaicin patch (HCCP) is

Updated on:March 28,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on: March 30,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on:March 30,2024

Physical models of a patient's brain help researchers treat neurological disorders and diseases

by David Pulgar,Virginia Commonwealth UniversityRavi Hadimani, Ph.D., associate professor of mechanical and nuclear engineering, leads a team of researchers who seek to use TMS to excite or inhi

Updated on: February 05,2024

Physical models of a patient's brain help researchers treat neurological disorders and diseases

by David Pulgar,Virginia Commonwealth UniversityRavi Hadimani, Ph.D., associate professor of mechanical and nuclear engineering, leads a team of researchers who seek to use TMS to excite or inhi

Updated on:February 05,2024

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on: March 03,2025

Removing large brain artery clot, chased with clot-buster shot may improve stroke outcomes

byAmerican Heart AssociationCredit: Pixabay/CC0 Public DomainRemoving a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in str

Updated on:March 03,2025