ssResearchers identify key steps to toxic protein accumulation in Alzheimer's and other diseases

by Tamara Bhandari,Washington University School of Medicine in St. LouisStress granules (red) fill stem cell-derived neurons (nuclei shown in blue) from a person with a mutation in the tau gene.

Updated on: March 02,2024

ssResearchers identify key steps to toxic protein accumulation in Alzheimer's and other diseases

by Tamara Bhandari,Washington University School of Medicine in St. LouisStress granules (red) fill stem cell-derived neurons (nuclei shown in blue) from a person with a mutation in the tau gene.

Updated on:March 02,2024

Exploring how astrocytes respond to spinal cord injury or stroke-induced tissue damage

by Ingrid Fadelli , Medical XpressWound repair astrocytes (in green) form a border around the inflammatory cells (in white) that invade an area of brain tissue damaged by a small stroke. This astrocyt

Updated on: July 31,2024

Exploring how astrocytes respond to spinal cord injury or stroke-induced tissue damage

by Ingrid Fadelli , Medical XpressWound repair astrocytes (in green) form a border around the inflammatory cells (in white) that invade an area of brain tissue damaged by a small stroke. This astrocyt

Updated on:July 31,2024

Alzheimer-type brain pathology after transplantation of dura mater

by University of ZurichBrown-colored A-beta plaques in the cerebral cortex in Alzheimer's disease. Credit: University Hospital ZurichUp to now Alzheimer's disease has not been recognized

Updated on: February 27,2024

Alzheimer-type brain pathology after transplantation of dura mater

by University of ZurichBrown-colored A-beta plaques in the cerebral cortex in Alzheimer's disease. Credit: University Hospital ZurichUp to now Alzheimer's disease has not been recognized

Updated on:February 27,2024

Alzheimer's trial screening data links high amyloid levels with early stage disease

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainThe first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer&#39

Updated on: April 20,2024

Alzheimer's trial screening data links high amyloid levels with early stage disease

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainThe first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer&#39

Updated on:April 20,2024

Study finds high prevalence of hidden brain changes in people with heart disease

byGeorge Institute for Global HealthCredit: Pixabay/CC0 Public DomainA new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of str

Updated on: March 28,2024

Study finds high prevalence of hidden brain changes in people with heart disease

byGeorge Institute for Global HealthCredit: Pixabay/CC0 Public DomainA new analysis involving over 13,000 people has found changes to blood vessels in the brain that can increase the risk of str

Updated on:March 28,2024

Make this Halloween a safe one for people with dementia

by Cara MurezHalloween is often frightening for loved ones who have dementia, but there are ways to keep it safe and not scary."Halloween can be very challenging and stressful for someone with de

Updated on: February 24,2024

Make this Halloween a safe one for people with dementia

by Cara MurezHalloween is often frightening for loved ones who have dementia, but there are ways to keep it safe and not scary."Halloween can be very challenging and stressful for someone with de

Updated on:February 24,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on: March 02,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on:March 02,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on: May 22,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on:May 22,2024

Study suggests that attention networks support changes in cortical organization and cognition during childhood

by Ingrid Fadelli , Medical XpressVentral attention network areas demonstrate high population-level degree centrality but pronounced functional changes across development. Credit:Nature Neurosci

Updated on: September 23,2024

Study suggests that attention networks support changes in cortical organization and cognition during childhood

by Ingrid Fadelli , Medical XpressVentral attention network areas demonstrate high population-level degree centrality but pronounced functional changes across development. Credit:Nature Neurosci

Updated on:September 23,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on: April 29,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on:April 29,2024

Brain organoids reveal in detail the harms of prenatal alcohol exposure

by University of California - San DiegoLab-grown brain organoids help researchers explore early stages of human brain development. Credit: UC San Diego Health SciencesAlcohol consumption during p

Updated on: February 21,2024

Brain organoids reveal in detail the harms of prenatal alcohol exposure

by University of California - San DiegoLab-grown brain organoids help researchers explore early stages of human brain development. Credit: UC San Diego Health SciencesAlcohol consumption during p

Updated on:February 21,2024