First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on: June 20,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on:June 20,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on: June 01,2024

Unusual mechanism in rare mutation associated with Alzheimer's uncovered

by University of Chicago Medical CenterPET scan of a human brain with Alzheimer's disease. Credit: public domainA novel mechanism has been identified that might explain why a rare mutation is

Updated on:June 01,2024

Recurrent brain trauma may increase Alzheimer's risk

by Radiological Society of North AmericaParametric maps of amyloid deposition in healthy control participants (A and B) and blast-exposed military instructors (C and D) at baseline (A and C) and

Updated on: June 01,2024

Recurrent brain trauma may increase Alzheimer's risk

by Radiological Society of North AmericaParametric maps of amyloid deposition in healthy control participants (A and B) and blast-exposed military instructors (C and D) at baseline (A and C) and

Updated on:June 01,2024

Pilot study shows promise for remote cognitive rehabilitation for multiple sclerosis patients

by Kessler FoundationCredit: Anna Shvets from PexelsA pilot study shows promise for a new treatment option for individuals with memory impairments caused by multiple sclerosis (MS). Thearticle,

Updated on: July 08,2024

Pilot study shows promise for remote cognitive rehabilitation for multiple sclerosis patients

by Kessler FoundationCredit: Anna Shvets from PexelsA pilot study shows promise for a new treatment option for individuals with memory impairments caused by multiple sclerosis (MS). Thearticle,

Updated on:July 08,2024

People who cannot read may be three times as likely to develop dementia

by American Academy of NeurologyCredit: CC0 Public DomainNew research has found that people who are illiterate, meaning they never learned to read or write, may have nearly three times greater ri

Updated on: May 05,2024

People who cannot read may be three times as likely to develop dementia

by American Academy of NeurologyCredit: CC0 Public DomainNew research has found that people who are illiterate, meaning they never learned to read or write, may have nearly three times greater ri

Updated on:May 05,2024

Study reveals how, when and where non-invasive brain stimulation influences neuronal activity and cognition

byMonash UniversityOverall response time modulations in humans and in monkeys. Credit:Brain(2024). DOI: 10.1093/brain/awae273Brain stimulation using electrodes placed on the head has

Updated on: September 23,2024

Study reveals how, when and where non-invasive brain stimulation influences neuronal activity and cognition

byMonash UniversityOverall response time modulations in humans and in monkeys. Credit:Brain(2024). DOI: 10.1093/brain/awae273Brain stimulation using electrodes placed on the head has

Updated on:September 23,2024

Extra-large synapses could be a cause of schizophrenia

by RIKENExtra-strong synapses could play an important role in psychiatric disorders such as schizophrenia, a study by RIKEN researchers finds. Credit: Equinox Graphics/Science Photo LibrarySchizo

Updated on: February 03,2024

Extra-large synapses could be a cause of schizophrenia

by RIKENExtra-strong synapses could play an important role in psychiatric disorders such as schizophrenia, a study by RIKEN researchers finds. Credit: Equinox Graphics/Science Photo LibrarySchizo

Updated on:February 03,2024

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on: April 07,2024

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on:April 07,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on: September 03,2024

Epigenetics blood markers can help understand dementia risk

byUniversity of ExeterOverview of the model generation. The model generation workflow consists of model training in the EXTEND and EMIF-AD cohorts using two different approaches. Credit:Al

Updated on:September 03,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on: August 08,2024

How astrocytes and perineuronal nets cooperate to sustain synaptic homeostasis

by Ingrid Fadelli , Medical XpressConfocal micrographs showing close association between Perineuronal nets (magenta) and astrocytes (green) in mouse cerebral cortex. Credit: Bhanu TewariSynapses are s

Updated on:August 08,2024

Researchers discover role of microglia during early progression of Alzheimer's disease

by Boston University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have determined how toxic tau fib

Updated on: February 26,2024

Researchers discover role of microglia during early progression of Alzheimer's disease

by Boston University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have determined how toxic tau fib

Updated on:February 26,2024