Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on: April 20,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on:April 20,2024

New alteration in the brains of people with Alzheimer's discovered

by Spanish National Research Council (CSIC)Credit: Unsplash/CC0 Public DomainDespite the important advances in research in recent years, the etiopathogenesis of Alzheimer's disease is still not fu

Updated on: April 20,2024

New alteration in the brains of people with Alzheimer's discovered

by Spanish National Research Council (CSIC)Credit: Unsplash/CC0 Public DomainDespite the important advances in research in recent years, the etiopathogenesis of Alzheimer's disease is still not fu

Updated on:April 20,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on: February 21,2024

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on:February 21,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Statin use reduces mortality and stroke risk in dementia patients, new study shows

by The European Academy of NeurologyThe use of statins is significantly associated with a reduction in the risk of mortality in dementia patients, new research presented today at the 5th European Acad

Updated on: March 07,2024

Statin use reduces mortality and stroke risk in dementia patients, new study shows

by The European Academy of NeurologyThe use of statins is significantly associated with a reduction in the risk of mortality in dementia patients, new research presented today at the 5th European Acad

Updated on:March 07,2024

Neuroscientists discover interactions between brain waves and nerve cells during human memory processes

by University Hospital of BonnIllustration of the hypothesis that human associative object–location memory is linked to the coactivity of object cells and place cells during hippocampal ripples. We pr

Updated on: March 13,2024

Neuroscientists discover interactions between brain waves and nerve cells during human memory processes

by University Hospital of BonnIllustration of the hypothesis that human associative object–location memory is linked to the coactivity of object cells and place cells during hippocampal ripples. We pr

Updated on:March 13,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on: October 09,2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on:October 09,2024

The brain pulsates differently in people suffering from Alzheimer's disease

by University of OuluIn the magnetic resonance image, a healthy brain is higher and a lower one with Alzheimer's disease. Pulsations in the brain appear as red signals at the frequency of the hear

Updated on: April 20,2024

The brain pulsates differently in people suffering from Alzheimer's disease

by University of OuluIn the magnetic resonance image, a healthy brain is higher and a lower one with Alzheimer's disease. Pulsations in the brain appear as red signals at the frequency of the hear

Updated on:April 20,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on: April 29,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on:April 29,2024