Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Alzheimer's and an unusual molecular chaperone

by University of KonstanzPET scan of a human brain with Alzheimer's disease. Credit: public domainAmong the hallmarks of Alzheimer's disease are the Alzheimer fibrils, deposits of the tau

Updated on: April 20,2024

Alzheimer's and an unusual molecular chaperone

by University of KonstanzPET scan of a human brain with Alzheimer's disease. Credit: public domainAmong the hallmarks of Alzheimer's disease are the Alzheimer fibrils, deposits of the tau

Updated on:April 20,2024

Healthy lifestyle linked to better cognition for oldest adults—regardless of genetic risk

by Public Library of ScienceCredit: Unsplash/CC0 Public DomainA new analysis of adults aged 80 years and older shows that a healthier lifestyle is associated with a lower risk of cognitive impair

Updated on: June 24,2024

Healthy lifestyle linked to better cognition for oldest adults—regardless of genetic risk

by Public Library of ScienceCredit: Unsplash/CC0 Public DomainA new analysis of adults aged 80 years and older shows that a healthier lifestyle is associated with a lower risk of cognitive impair

Updated on:June 24,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on: February 03,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on:February 03,2024

Gout strongly associated with reduced gray matter and increased neurodegenerative disease

by Justin Jackson , Medical XpressDifferences in regional gray matter volume between participants with gout (n = 1,165) and controls (n = 32,202), as analyzed by voxel-based morphometry. Blue regions

Updated on: May 13,2024

Gout strongly associated with reduced gray matter and increased neurodegenerative disease

by Justin Jackson , Medical XpressDifferences in regional gray matter volume between participants with gout (n = 1,165) and controls (n = 32,202), as analyzed by voxel-based morphometry. Blue regions

Updated on:May 13,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on: May 08,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on:May 08,2024

Facebook app offers opportunity to help unpaid Alzheimer's caregivers via friendsourcing

by Indiana UniversityDavid Wilkerson, an assistant professor in the IU School of Social Work and a member of the Facebook app research team. Credit: IU School of Social WorkResearchers at IUPUI h

Updated on: March 30,2024

Facebook app offers opportunity to help unpaid Alzheimer's caregivers via friendsourcing

by Indiana UniversityDavid Wilkerson, an assistant professor in the IU School of Social Work and a member of the Facebook app research team. Credit: IU School of Social WorkResearchers at IUPUI h

Updated on:March 30,2024

Why are migraines worse during your period? Study points to progesterone, offering a new treatment target

by Suchitra Joshi and Jaideep Kapur,The ConversationHormone levels change throughout the menstrual cycle. Credit:Draper et al. 2018/Scientific Reports,CC BY-SAMigraines are throbbing

Updated on: August 08,2024

Why are migraines worse during your period? Study points to progesterone, offering a new treatment target

by Suchitra Joshi and Jaideep Kapur,The ConversationHormone levels change throughout the menstrual cycle. Credit:Draper et al. 2018/Scientific Reports,CC BY-SAMigraines are throbbing

Updated on:August 08,2024

Analyzing internal world models of humans, animals and AI

byUniversity of FreiburgCredit: Pixabay/CC0 Public DomainA team of scientists led by Prof. Dr. Ilka Diester, Professor of Optophysiology and spokesperson of the BrainLinks-BrainTools research ce

Updated on: July 31,2024

Analyzing internal world models of humans, animals and AI

byUniversity of FreiburgCredit: Pixabay/CC0 Public DomainA team of scientists led by Prof. Dr. Ilka Diester, Professor of Optophysiology and spokesperson of the BrainLinks-BrainTools research ce

Updated on:July 31,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Alzheimer's in one sibling raises risk of shortened lifespan in others

by Leigh Hopper,University of Southern CaliforniaCredit: CC0 Public DomainAn Alzheimer's diagnosis in a sibling raises the risk of a shortened lifespan in other family members—even those wit

Updated on: February 24,2024

Alzheimer's in one sibling raises risk of shortened lifespan in others

by Leigh Hopper,University of Southern CaliforniaCredit: CC0 Public DomainAn Alzheimer's diagnosis in a sibling raises the risk of a shortened lifespan in other family members—even those wit

Updated on:February 24,2024

'Bugs' in the gut might predict dementia in the brain

by American Heart AssociationCredit: CC0 Public DomainThe makeup of bacteria and other microbes in the gut may have a direct association with dementia risk, according to preliminary research to b

Updated on: May 05,2024

'Bugs' in the gut might predict dementia in the brain

by American Heart AssociationCredit: CC0 Public DomainThe makeup of bacteria and other microbes in the gut may have a direct association with dementia risk, according to preliminary research to b

Updated on:May 05,2024