First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on: March 02,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on:March 02,2024

How retrotransposons control the brain

by John Hewitt , Medical XpressCredit: WikipediaAround half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in va

Updated on: June 01,2024

How retrotransposons control the brain

by John Hewitt , Medical XpressCredit: WikipediaAround half of the genome is made up of transposable elements or 'jumping genes' that derive from ancient viral integrations. They persist in va

Updated on:June 01,2024

The brain pulsates differently in people suffering from Alzheimer's disease

by University of OuluIn the magnetic resonance image, a healthy brain is higher and a lower one with Alzheimer's disease. Pulsations in the brain appear as red signals at the frequency of the hear

Updated on: April 20,2024

The brain pulsates differently in people suffering from Alzheimer's disease

by University of OuluIn the magnetic resonance image, a healthy brain is higher and a lower one with Alzheimer's disease. Pulsations in the brain appear as red signals at the frequency of the hear

Updated on:April 20,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on: April 29,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on:April 29,2024

How aggression-promoting brain peptide works in fruit flies

by Salk InstituteA fruit fly brain showing male-specific tachykininergic neurons (magenta), which make the neuropeptide tachykinin, and neurons that express TkR86C (green), which receive tachykin

Updated on: February 18,2024

How aggression-promoting brain peptide works in fruit flies

by Salk InstituteA fruit fly brain showing male-specific tachykininergic neurons (magenta), which make the neuropeptide tachykinin, and neurons that express TkR86C (green), which receive tachykin

Updated on:February 18,2024

Brain organoids reveal in detail the harms of prenatal alcohol exposure

by University of California - San DiegoLab-grown brain organoids help researchers explore early stages of human brain development. Credit: UC San Diego Health SciencesAlcohol consumption during p

Updated on: February 21,2024

Brain organoids reveal in detail the harms of prenatal alcohol exposure

by University of California - San DiegoLab-grown brain organoids help researchers explore early stages of human brain development. Credit: UC San Diego Health SciencesAlcohol consumption during p

Updated on:February 21,2024

Dementia found to be the dominant risk factor for COVID in elderly care

by University of GothenburgHazard ratios (HR) and 95% Confidence intervals (CI) of the relationship between individual-level factors (age, sex, education, dementia, cardiovascular disease, lung d

Updated on: May 06,2024

Dementia found to be the dominant risk factor for COVID in elderly care

by University of GothenburgHazard ratios (HR) and 95% Confidence intervals (CI) of the relationship between individual-level factors (age, sex, education, dementia, cardiovascular disease, lung d

Updated on:May 06,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on: March 30,2024

Clinical trial results for lecanemab are a significant step for Alzheimer's, but not a historic breakthrough

by University of New South WalesAmyloid plaques and neurofibrillary tangles occur in the brains of patients with Alzheimer's disease. Credit: Ian JosonPartner companies Eisai and Biogen recen

Updated on:March 30,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on: March 30,2024

How blocking a neural receptor responsible for addiction could reduce alcohol use

by The Scripps Research InstituteTime course of alcohol self-administration acquisition across 21 training sessions and escalation of drinking during week 6 of CIE vapor exposure. (A) Male and fe

Updated on:March 30,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on: January 12,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on:January 12,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on: December 11,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on:December 11,2024