Researchers discover role of microglia during early progression of Alzheimer's disease

by Boston University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have determined how toxic tau fib

Updated on: February 26,2024 11

Researchers discover role of microglia during early progression of Alzheimer's disease

by Boston University Medical CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.For the first time, researchers have determined how toxic tau fib

Updated on:February 26,2024 11

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on: February 26,2024 10

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on:February 26,2024 10

Alzheimer's: Proteomics gives clues toward alternatives to amyloid

by Emory UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In Alzheimer's research, one particular protein looms large: plaque-forming a

Updated on: April 07,2024 10

Alzheimer's: Proteomics gives clues toward alternatives to amyloid

by Emory UniversityDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In Alzheimer's research, one particular protein looms large: plaque-forming a

Updated on:April 07,2024 10

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on: April 20,2024 20

Single-cell dissection of Alzheimer's vascular changes across six brain regions

by Rachel Gordon, MIT Computer Science & Artificial Intelligence LabExperimental validation of adDEGs. a. Chromogenic RNAscope for ABCC9 and SLC6A1. Prefrontal cortex brain sections (n = 4 for AD

Updated on:April 20,2024 20

Eli Lilly hopeful of Alzheimer's drug approval after promising results

Credit: Unsplash/CC0 Public DomainA second Alzheimer's drug proven to slow cognitive decline was a step closer to US approval on Monday after clinical trial results published in a top journal conf

Updated on: March 09,2024 16

Eli Lilly hopeful of Alzheimer's drug approval after promising results

Credit: Unsplash/CC0 Public DomainA second Alzheimer's drug proven to slow cognitive decline was a step closer to US approval on Monday after clinical trial results published in a top journal conf

Updated on:March 09,2024 16

Tiny blood vessels in the brain could be the key in treating vascular dementia

by University of SouthamptonTiny blood vessels in the brain could be the key in treating vascular dementia. Credit: University of SouthamptonResearchers from the University of Southampton are to

Updated on: May 18,2024 8

Tiny blood vessels in the brain could be the key in treating vascular dementia

by University of SouthamptonTiny blood vessels in the brain could be the key in treating vascular dementia. Credit: University of SouthamptonResearchers from the University of Southampton are to

Updated on:May 18,2024 8

International study uncovers a molecule that could alleviate stroke-related brain injury

byThe Hospital for Sick ChildrenCredit: CC0 Public DomainA newly developed molecule, LK-2, could inform new therapies for stroke-related brain injury, find scientists at The Hospital for Sick Ch

Updated on: July 17,2024 0

International study uncovers a molecule that could alleviate stroke-related brain injury

byThe Hospital for Sick ChildrenCredit: CC0 Public DomainA newly developed molecule, LK-2, could inform new therapies for stroke-related brain injury, find scientists at The Hospital for Sick Ch

Updated on:July 17,2024 0

Untangling the threads of early onset dementia

by Lynda De Widt, Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainChanges in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementi

Updated on: April 06,2024 0

Untangling the threads of early onset dementia

by Lynda De Widt, Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainChanges in personality, behavior and language are hallmarks of frontotemporal dementia (FTD), the most common form of dementi

Updated on:April 06,2024 0

Having dementia and reduction in social participation are associated with increased depression and anxiety

by IOS PressMental health and activity participation by dementia status per year of assessment. A) Proportion of depressive symptoms. B) Proportion of anxiety. C) Mean score of social activity. D

Updated on: June 07,2024 5

Having dementia and reduction in social participation are associated with increased depression and anxiety

by IOS PressMental health and activity participation by dementia status per year of assessment. A) Proportion of depressive symptoms. B) Proportion of anxiety. C) Mean score of social activity. D

Updated on:June 07,2024 5

First U.S. clinical trial using adult allogeneic stem cells to treat Alzheimer's disease

by Emory UniversityA new study to assess the safety, tolerability and preliminary efficacy of allogeneic stem cells in persons with mild to moderate dementia due to Alzheimer's disease (AD) i

Updated on: March 07,2024 20

First U.S. clinical trial using adult allogeneic stem cells to treat Alzheimer's disease

by Emory UniversityA new study to assess the safety, tolerability and preliminary efficacy of allogeneic stem cells in persons with mild to moderate dementia due to Alzheimer's disease (AD) i

Updated on:March 07,2024 20

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on: May 28,2024 3

Skin cells from frontotemporal dementia patients may reveal disease mechanisms and biomarkers for drug research

by University of Eastern FinlandFibroblasts of C9-HRE carriers show unaltered C9orf72 levels, express RNA foci, but do not display DPR proteins. a TaqMan assay from fibroblast RNA for C9orf72 all

Updated on:May 28,2024 3

Neuroscientist uses AI to map learning, decision-making, to discover how brains work

by Stacey DeLoye,University of FloridaMeta-learning of RL. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01485-3With trial and error, repetition and praise, when a puppy

Updated on: March 13,2024 7

Neuroscientist uses AI to map learning, decision-making, to discover how brains work

by Stacey DeLoye,University of FloridaMeta-learning of RL. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01485-3With trial and error, repetition and praise, when a puppy

Updated on:March 13,2024 7