Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on: March 26,2024

Early-life stress can disrupt maturation of brain's reward circuits, promoting disorders

by University of California, IrvineA projection of CRH/GABA neurons in the medial BLA to the medial NAc shell.a–cRetrograde tracing of CRH+neuronal inputs to medial NAc shell of

Updated on:March 26,2024

New alteration in the brains of people with Alzheimer's discovered

by Spanish National Research Council (CSIC)Credit: Unsplash/CC0 Public DomainDespite the important advances in research in recent years, the etiopathogenesis of Alzheimer's disease is still not fu

Updated on: April 20,2024

New alteration in the brains of people with Alzheimer's discovered

by Spanish National Research Council (CSIC)Credit: Unsplash/CC0 Public DomainDespite the important advances in research in recent years, the etiopathogenesis of Alzheimer's disease is still not fu

Updated on:April 20,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Researchers find some evidence of link between stress, Alzheimer's disease

by University of FloridaTodd Golde, M.D., Ph.D., director of the UF Center for Translational Research in Neurodegenerative Disease and a professor in the UF College of Medicine's department o

Updated on: February 26,2024

Researchers find some evidence of link between stress, Alzheimer's disease

by University of FloridaTodd Golde, M.D., Ph.D., director of the UF Center for Translational Research in Neurodegenerative Disease and a professor in the UF College of Medicine's department o

Updated on:February 26,2024

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on: February 21,2024

How the brain encodes social rank and 'winning mindset'

by Salk InstituteMice that have formed a social hierarchy get placed in a box where they compete for a food reward. Salk scientists can use brain readouts to accurately predict which animal will

Updated on:February 21,2024

Our brains take rhythmic snapshots of the world as we walk

by Matthew Davidson,The ConversationCredit: Pixabay/CC0 Public DomainFor decades, psychology departments around the world have studied human behavior in darkened laboratories that restrict natur

Updated on: March 19,2024

Our brains take rhythmic snapshots of the world as we walk

by Matthew Davidson,The ConversationCredit: Pixabay/CC0 Public DomainFor decades, psychology departments around the world have studied human behavior in darkened laboratories that restrict natur

Updated on:March 19,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on: March 02,2024

Phase I clinical trial shows treatment designed to clear senescent cells in Alzheimer's disease is safe

by Atrium Health Wake Forest BaptistSenescent neurons are represented by areas of blue, red and white. Senescent cells are old, sick cells that cannot properly repair themselves and don't die

Updated on:March 02,2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on: October 09,2024

Largest-ever genetic study of epilepsy finds possible therapeutic targets

by Ari Navetta,Broad Institute of MIT and HarvardEpilepsy genetic architecture from large-scale genetic association studies. Credit:Nature Neuroscience(2024). DOI: 10.1038/s41593-024

Updated on:October 09,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on: April 20,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on:April 20,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on: April 29,2024

Brain health 'Check-in' tool to help reduce dementia risk

by University College LondonCredit: Alzheimer's Research UKA free new digital tool has been launched by Alzheimer's Research UK, supported by evidence from UCL researchers, to help people

Updated on:April 29,2024

Racial differences in Alzheimer's disease unveiled

by Washington University School of MedicineCredit: CC0 Public DomainAfrican-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why becaus

Updated on: April 08,2024

Racial differences in Alzheimer's disease unveiled

by Washington University School of MedicineCredit: CC0 Public DomainAfrican-Americans may be twice as likely as Caucasian Americans to develop Alzheimer's disease, but nobody knows why becaus

Updated on:April 08,2024