A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on: March 25,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on:March 25,2024

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on: April 07,2024

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on:April 07,2024

Making long-term memories requires DNA damage, researchers discover

by Albert Einstein College of MedicineFragments released from the nuclei of neurons undergoing DNA damage during learning: DNA (large white dot at center right), histones (purple), and transcript

Updated on: March 30,2024

Making long-term memories requires DNA damage, researchers discover

by Albert Einstein College of MedicineFragments released from the nuclei of neurons undergoing DNA damage during learning: DNA (large white dot at center right), histones (purple), and transcript

Updated on:March 30,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

More than just neurons: Scientists create new model for studying human brain inflammation

bySalk InstituteHuman astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons s

Updated on: March 13,2024

More than just neurons: Scientists create new model for studying human brain inflammation

bySalk InstituteHuman astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons s

Updated on:March 13,2024

Alzheimer's in one sibling raises risk of shortened lifespan in others

by Leigh Hopper,University of Southern CaliforniaCredit: CC0 Public DomainAn Alzheimer's diagnosis in a sibling raises the risk of a shortened lifespan in other family members—even those wit

Updated on: February 24,2024

Alzheimer's in one sibling raises risk of shortened lifespan in others

by Leigh Hopper,University of Southern CaliforniaCredit: CC0 Public DomainAn Alzheimer's diagnosis in a sibling raises the risk of a shortened lifespan in other family members—even those wit

Updated on:February 24,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Why are migraines worse during your period? Study points to progesterone, offering a new treatment target

by Suchitra Joshi and Jaideep Kapur,The ConversationHormone levels change throughout the menstrual cycle. Credit:Draper et al. 2018/Scientific Reports,CC BY-SAMigraines are throbbing

Updated on: August 08,2024

Why are migraines worse during your period? Study points to progesterone, offering a new treatment target

by Suchitra Joshi and Jaideep Kapur,The ConversationHormone levels change throughout the menstrual cycle. Credit:Draper et al. 2018/Scientific Reports,CC BY-SAMigraines are throbbing

Updated on:August 08,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

Healthy lifestyle linked to better cognition for oldest adults—regardless of genetic risk

by Public Library of ScienceCredit: Unsplash/CC0 Public DomainA new analysis of adults aged 80 years and older shows that a healthier lifestyle is associated with a lower risk of cognitive impair

Updated on: June 24,2024

Healthy lifestyle linked to better cognition for oldest adults—regardless of genetic risk

by Public Library of ScienceCredit: Unsplash/CC0 Public DomainA new analysis of adults aged 80 years and older shows that a healthier lifestyle is associated with a lower risk of cognitive impair

Updated on:June 24,2024

Alzheimer's disease impacts women in higher numbers and different ways

by Leigh Hopper,University of Southern CaliforniaAlzheimer’s disease strikes far more women than men, and the reason for this discrepancy isn’t yet known. Credit: PixabayNovember is Alzheimer&#3

Updated on: April 08,2024

Alzheimer's disease impacts women in higher numbers and different ways

by Leigh Hopper,University of Southern CaliforniaAlzheimer’s disease strikes far more women than men, and the reason for this discrepancy isn’t yet known. Credit: PixabayNovember is Alzheimer&#3

Updated on:April 08,2024

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on: April 18,2024

Alzheimer's protein is likely held together with many weak chemical interactions

by University of TokyoCredit: CC0 Public DomainThe chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide

Updated on:April 18,2024