Thinning of brain region may signal dementia risk 5–10 years before symptoms

by Will Sansom,University of Texas Health Science Center at San AntonioStrengths of significant association (regression t values) for gray matter thickness in Alzheimer's disease (AD) dement

Updated on: March 13,2024

Thinning of brain region may signal dementia risk 5–10 years before symptoms

by Will Sansom,University of Texas Health Science Center at San AntonioStrengths of significant association (regression t values) for gray matter thickness in Alzheimer's disease (AD) dement

Updated on:March 13,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on: April 20,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on:April 20,2024

Focused ultrasound shown to enhance the delivery of promising therapeutic for Alzheimer's disease

by Samantha Sexton, Sunnybrook Research InstituteNew neurons (seen here in green) can be generated in the hippocampus, a brain region involved in learning and memory. In the study, the use of focused

Updated on: July 04,2024

Focused ultrasound shown to enhance the delivery of promising therapeutic for Alzheimer's disease

by Samantha Sexton, Sunnybrook Research InstituteNew neurons (seen here in green) can be generated in the hippocampus, a brain region involved in learning and memory. In the study, the use of focused

Updated on:July 04,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on: June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on:June 14,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

Researchers develop new brain network modeling tools to advance Alzheimer's disease research

by Indiana University School of MedicineCredit: CC0 Public DomainIndiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously dev

Updated on: February 24,2024

Researchers develop new brain network modeling tools to advance Alzheimer's disease research

by Indiana University School of MedicineCredit: CC0 Public DomainIndiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously dev

Updated on:February 24,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on: March 13,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on:March 13,2024

Insurers balk at paying for Biogen's $56,000-a-year Alzheimer's treatment

by John Tozzi, Angelica Lavito and Anushree DaveCredit: CC0 Public DomainU.S. health insurers say they want more proof before paying for Biogen Inc.'s Aduhelm, stalling sales of the costly new Alz

Updated on: April 29,2024

Insurers balk at paying for Biogen's $56,000-a-year Alzheimer's treatment

by John Tozzi, Angelica Lavito and Anushree DaveCredit: CC0 Public DomainU.S. health insurers say they want more proof before paying for Biogen Inc.'s Aduhelm, stalling sales of the costly new Alz

Updated on:April 29,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on: February 27,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on:February 27,2024

Improved fitness can mean living longer without dementia

by Norwegian University of Science and TechnologyCredit: AI-generated imageStaying fit or improving fitness over time should be a goal for anyone who wants to reduce the likelihood of getting dem

Updated on: June 24,2024

Improved fitness can mean living longer without dementia

by Norwegian University of Science and TechnologyCredit: AI-generated imageStaying fit or improving fitness over time should be a goal for anyone who wants to reduce the likelihood of getting dem

Updated on:June 24,2024

Healthy lifestyle may offset genetic risk of dementia

by University of ExeterCredit: CC0 Public DomainLiving a healthy lifestyle may help offset a person's genetic risk of dementia, according to new research.The study was led by the University o

Updated on: June 24,2024

Healthy lifestyle may offset genetic risk of dementia

by University of ExeterCredit: CC0 Public DomainLiving a healthy lifestyle may help offset a person's genetic risk of dementia, according to new research.The study was led by the University o

Updated on:June 24,2024