Alzheimer's medications, milestones and disease management

by Jeremy Deutchman,University of Southern CaliforniaCredit: Pixabay/CC0 Public DomainAlzheimer's disease and the urgent need for more effective treatments have been making headlines this ye

Updated on: April 08,2024

Alzheimer's medications, milestones and disease management

by Jeremy Deutchman,University of Southern CaliforniaCredit: Pixabay/CC0 Public DomainAlzheimer's disease and the urgent need for more effective treatments have been making headlines this ye

Updated on:April 08,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on: March 25,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on:March 25,2024

Alzheimer's trial screening data links high amyloid levels with early stage disease

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainThe first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer&#39

Updated on: April 20,2024

Alzheimer's trial screening data links high amyloid levels with early stage disease

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainThe first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer&#39

Updated on:April 20,2024

Publication highlights care challenges of dementia-related psychosis

by The Gerontological Society of AmericaCredit: CC0 Public DomainIt is estimated that over 2 million Americans with dementia experience delusions (false beliefs) and hallucinations (seeing or hearing

Updated on: May 11,2024

Publication highlights care challenges of dementia-related psychosis

by The Gerontological Society of AmericaCredit: CC0 Public DomainIt is estimated that over 2 million Americans with dementia experience delusions (false beliefs) and hallucinations (seeing or hearing

Updated on:May 11,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on: March 07,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on:March 07,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on: March 13,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on:March 13,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on: May 22,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on:May 22,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on: March 30,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on:March 30,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on: February 03,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on:February 03,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on: June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on:June 14,2024

Extra-large synapses could be a cause of schizophrenia

by RIKENExtra-strong synapses could play an important role in psychiatric disorders such as schizophrenia, a study by RIKEN researchers finds. Credit: Equinox Graphics/Science Photo LibrarySchizo

Updated on: February 03,2024

Extra-large synapses could be a cause of schizophrenia

by RIKENExtra-strong synapses could play an important role in psychiatric disorders such as schizophrenia, a study by RIKEN researchers finds. Credit: Equinox Graphics/Science Photo LibrarySchizo

Updated on:February 03,2024

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on: April 07,2024

Alzheimer's brain barrier damage theory could pave way for new treatments

by University of ReadingCredit: Pixabay/CC0 Public DomainAlzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brai

Updated on:April 07,2024