New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

Alzheimer's drug gets FDA panel's backing, setting the stage for broader use

by Matthew PerroneThis Dec. 21, 2022, image provided by Eisai in January 2023 shows vials and packaging for their medication Leqembi. On Friday, June 9, 2023, health advisers backed the full approval

Updated on: April 16,2024

Alzheimer's drug gets FDA panel's backing, setting the stage for broader use

by Matthew PerroneThis Dec. 21, 2022, image provided by Eisai in January 2023 shows vials and packaging for their medication Leqembi. On Friday, June 9, 2023, health advisers backed the full approval

Updated on:April 16,2024

New research explains how brain blood vessels are formed

by Université libre de BruxellesMmp25 as a regulator of brain-specific angiogenesis.a, The TC genotype in mosaic sprouts during brain vascular invasion (36 hpf,n = 23 sprouts) and tru

Updated on: April 06,2024

New research explains how brain blood vessels are formed

by Université libre de BruxellesMmp25 as a regulator of brain-specific angiogenesis.a, The TC genotype in mosaic sprouts during brain vascular invasion (36 hpf,n = 23 sprouts) and tru

Updated on:April 06,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on: April 01,2024

Successful Phase 2 clinical trial for neflamapimod in mild-to-moderate Lewy body dementia

by University of North Carolina at Chapel Hill School of MedicineCredit: CC0 Public DomainEIP Pharma announced on October 6 that a phase 2 study in patients with mild-to-moderate Lewy body dement

Updated on:April 01,2024

How the brain's immune system worsens epilepsy

by Richard C. Lewis,University of IowaUniversity of Iowa biologists have definitively linked the brain's immune system to epilepsy. The caption shows the sequence of events that triggers wor

Updated on: February 21,2024

How the brain's immune system worsens epilepsy

by Richard C. Lewis,University of IowaUniversity of Iowa biologists have definitively linked the brain's immune system to epilepsy. The caption shows the sequence of events that triggers wor

Updated on:February 21,2024

Dementia and self-harm: Why it's crucial to support patients in first year after diagnosis

by Lachlan Gilbert,University of New South WalesCredit: AI-generated imagePeople diagnosed with dementia are more likely to self-harm within the first six to 12 months after initial diagnosis, h

Updated on: May 08,2024

Dementia and self-harm: Why it's crucial to support patients in first year after diagnosis

by Lachlan Gilbert,University of New South WalesCredit: AI-generated imagePeople diagnosed with dementia are more likely to self-harm within the first six to 12 months after initial diagnosis, h

Updated on:May 08,2024

Brain mapping technique reveals insights into brain's higher functions

byUniversity of BirminghamHigher-order brain mapping: schematic of the approach and applications. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54472-yA new way of mapp

Updated on: December 17,2024

Brain mapping technique reveals insights into brain's higher functions

byUniversity of BirminghamHigher-order brain mapping: schematic of the approach and applications. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54472-yA new way of mapp

Updated on:December 17,2024

Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on: May 06,2024

Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on:May 06,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on: March 13,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on:March 13,2024

Study indicates possible link between chronic stress and Alzheimer's disease

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainResearchers from Karolinska Institutet have publisheda studyinAlzheimer's Research & Therapythat addresse

Updated on: March 02,2024

Study indicates possible link between chronic stress and Alzheimer's disease

by Karolinska InstitutetCredit: Unsplash/CC0 Public DomainResearchers from Karolinska Institutet have publisheda studyinAlzheimer's Research & Therapythat addresse

Updated on:March 02,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on: February 27,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on:February 27,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on: January 12,2024

How molecules in the zebrafish brain indicate it's time to quit a fight

byRIKENCredit:Current Biology(2023). DOI: 10.1016/j.cub.2023.03.087Two RIKEN neuroscientists have uncovered a molecular switch in the zebrafish brain that causes a fish to quit fight

Updated on:January 12,2024