New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

People with dementia could be missing out on post-diagnosis care

by Newcastle UniversityCredit: Unsplash/CC0 Public DomainA new report has found that as many as 85% of people with dementia could be missing out on important post-diagnosis care.Now world-leading

Updated on: May 09,2024

People with dementia could be missing out on post-diagnosis care

by Newcastle UniversityCredit: Unsplash/CC0 Public DomainA new report has found that as many as 85% of people with dementia could be missing out on important post-diagnosis care.Now world-leading

Updated on:May 09,2024

Thinning of brain region may signal dementia risk 5–10 years before symptoms

by Will Sansom,University of Texas Health Science Center at San AntonioStrengths of significant association (regression t values) for gray matter thickness in Alzheimer's disease (AD) dement

Updated on: March 13,2024

Thinning of brain region may signal dementia risk 5–10 years before symptoms

by Will Sansom,University of Texas Health Science Center at San AntonioStrengths of significant association (regression t values) for gray matter thickness in Alzheimer's disease (AD) dement

Updated on:March 13,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on: April 20,2024

Microscopic blood vessel disease in the brain's white matter associated with worse cognition in Alzheimer's

by Medical College of Georgia at Augusta UniversityDr. Zsolt Bagi with coauthors Katie Anne Fopiano, AU graduate student, and Dr. Yanna Tian, who just earned her graduate degree from AU and has s

Updated on:April 20,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on: June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on:June 14,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on: February 05,2024

Connections between addictive drugs and brain function in mice

by John Spizzirri,Argonne National LaboratoryFigure 1. Experimental design for dopamine connectomics. (A) Adeno-associated viruses (AAVs) expressing Cre-dependent Apex2 were bilaterally injected

Updated on:February 05,2024

Researchers develop new brain network modeling tools to advance Alzheimer's disease research

by Indiana University School of MedicineCredit: CC0 Public DomainIndiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously dev

Updated on: February 24,2024

Researchers develop new brain network modeling tools to advance Alzheimer's disease research

by Indiana University School of MedicineCredit: CC0 Public DomainIndiana University researchers are collaborating on a novel approach to use neuroimaging and network modeling tools—previously dev

Updated on:February 24,2024

Dementia and self-harm: Why it's crucial to support patients in first year after diagnosis

by Lachlan Gilbert,University of New South WalesCredit: AI-generated imagePeople diagnosed with dementia are more likely to self-harm within the first six to 12 months after initial diagnosis, h

Updated on: May 08,2024

Dementia and self-harm: Why it's crucial to support patients in first year after diagnosis

by Lachlan Gilbert,University of New South WalesCredit: AI-generated imagePeople diagnosed with dementia are more likely to self-harm within the first six to 12 months after initial diagnosis, h

Updated on:May 08,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on: February 27,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on:February 27,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on: March 13,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on:March 13,2024

Socially active 60-year-olds face lower dementia risk

by University College LondonCredit: CC0 Public DomainBeing more socially active in your 50s and 60s predicts a lower risk of developing dementia later on, finds a new UCL-led study.Thelongi

Updated on: June 14,2024

Socially active 60-year-olds face lower dementia risk

by University College LondonCredit: CC0 Public DomainBeing more socially active in your 50s and 60s predicts a lower risk of developing dementia later on, finds a new UCL-led study.Thelongi

Updated on:June 14,2024

Gene ID'd as potential therapeutic target for dementia in Parkinson's

by Washington University School of MedicineClumps of the Parkinson's protein alpha-synuclein (red) are visible inside neurons (green) in the brain of a mouse. Researchers at Washington Univer

Updated on: June 14,2024

Gene ID'd as potential therapeutic target for dementia in Parkinson's

by Washington University School of MedicineClumps of the Parkinson's protein alpha-synuclein (red) are visible inside neurons (green) in the brain of a mouse. Researchers at Washington Univer

Updated on:June 14,2024