Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on: May 06,2024

Dementia risk scores have high error rates

by Lori SolomonCurrent dementia risk scores have high error rates and limited clinical utility for estimating 10-year risk, according to a study published online June 13 inJAMA Network Open.Mika

Updated on:May 06,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on: March 07,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on:March 07,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on: June 20,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on:June 20,2024

Mediterranean diet associated with decreased risk of dementia

by Newcastle UniversityCredit: CC0 Public DomainEating a traditional Mediterranean-type diet—rich in foods such as seafood, fruit, and nuts—may help reduce the risk of dementia by almost a quarte

Updated on: May 20,2024

Mediterranean diet associated with decreased risk of dementia

by Newcastle UniversityCredit: CC0 Public DomainEating a traditional Mediterranean-type diet—rich in foods such as seafood, fruit, and nuts—may help reduce the risk of dementia by almost a quarte

Updated on:May 20,2024

Can the healthy brain offer clues to curing Alzheimer's?

by The ConversationImage of brain with regions of the medial temporal lobe colour-coded"Have you cured Alzheimer's disease yet?"This is a common question people ask when they discov

Updated on: June 24,2024

Can the healthy brain offer clues to curing Alzheimer's?

by The ConversationImage of brain with regions of the medial temporal lobe colour-coded"Have you cured Alzheimer's disease yet?"This is a common question people ask when they discov

Updated on:June 24,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on: March 25,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on:March 25,2024

Use of feeding tubes decreases among nursing home residents with advanced dementia

by The JAMA Network JournalsIn a study appearing in the August 16 issue ofJAMA, Susan L. Mitchell, M.D., M.P.H., of Hebrew SeniorLife Institute for Aging Research, Harvard Medical School, B

Updated on: March 07,2024

Use of feeding tubes decreases among nursing home residents with advanced dementia

by The JAMA Network JournalsIn a study appearing in the August 16 issue ofJAMA, Susan L. Mitchell, M.D., M.P.H., of Hebrew SeniorLife Institute for Aging Research, Harvard Medical School, B

Updated on:March 07,2024

Alzheimer-type brain pathology after transplantation of dura mater

by University of ZurichBrown-colored A-beta plaques in the cerebral cortex in Alzheimer's disease. Credit: University Hospital ZurichUp to now Alzheimer's disease has not been recognized

Updated on: February 27,2024

Alzheimer-type brain pathology after transplantation of dura mater

by University of ZurichBrown-colored A-beta plaques in the cerebral cortex in Alzheimer's disease. Credit: University Hospital ZurichUp to now Alzheimer's disease has not been recognized

Updated on:February 27,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on: February 03,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on:February 03,2024

Form of B12 deficiency in cerebral spinal fluid found to negatively affect the central nervous system

by Bob Yirka , Medical XpressA patient with an unsual MRI and neurologic deficits eluded typical diagnostic tests.Credit: John PluvinageA large team of doctors and medical researchers with diver

Updated on: July 05,2024

Form of B12 deficiency in cerebral spinal fluid found to negatively affect the central nervous system

by Bob Yirka , Medical XpressA patient with an unsual MRI and neurologic deficits eluded typical diagnostic tests.Credit: John PluvinageA large team of doctors and medical researchers with diver

Updated on:July 05,2024

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on: March 28,2024

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on:March 28,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on: May 22,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on:May 22,2024