A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on: March 25,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on:March 25,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on: March 07,2024

Lack of brain shrinkage may help predict who develops dementia with Lewy bodies

by Mayo ClinicDementia with Lewy bodies is a progressive disease that causes hallucinations, decline in mental abilities, rigid muscles, slow movement and tremors. With symptoms similar to Alzhei

Updated on:March 07,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on: March 30,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on:March 30,2024

More than just neurons: Scientists create new model for studying human brain inflammation

bySalk InstituteHuman astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons s

Updated on: March 13,2024

More than just neurons: Scientists create new model for studying human brain inflammation

bySalk InstituteHuman astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons s

Updated on:March 13,2024

Black people less likely to receive dementia-related medications

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainBlack people are receiving medications for dementia less often than white people, according to a preliminary study released today,

Updated on: June 07,2024

Black people less likely to receive dementia-related medications

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainBlack people are receiving medications for dementia less often than white people, according to a preliminary study released today,

Updated on:June 07,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on: March 07,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on:March 07,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on: June 20,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on:June 20,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on: May 22,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on:May 22,2024

Tactile imagery used to improve rehabilitation of patients with motor disorders

by Skolkovo Institute of Science and TechnologyBrain MRI projection. Credit: SkoltechSkoltech researchers in collaboration with Immanuel Kant Baltic Federal University, Lomonosov Moscow State Uni

Updated on: February 05,2024

Tactile imagery used to improve rehabilitation of patients with motor disorders

by Skolkovo Institute of Science and TechnologyBrain MRI projection. Credit: SkoltechSkoltech researchers in collaboration with Immanuel Kant Baltic Federal University, Lomonosov Moscow State Uni

Updated on:February 05,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on: February 27,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on:February 27,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on: June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on:June 14,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on: March 28,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on:March 28,2024