Alzheimer's medications, milestones and disease management

by Jeremy Deutchman,University of Southern CaliforniaCredit: Pixabay/CC0 Public DomainAlzheimer's disease and the urgent need for more effective treatments have been making headlines this ye

Updated on: April 08,2024

Alzheimer's medications, milestones and disease management

by Jeremy Deutchman,University of Southern CaliforniaCredit: Pixabay/CC0 Public DomainAlzheimer's disease and the urgent need for more effective treatments have been making headlines this ye

Updated on:April 08,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on: May 08,2024

Chatbots for dementia patients and caregivers need more work

by Holly Ober,University of California - RiversideCredit: CC0 Public DomainChatbots hold promise for dementia patient or caregiver support, but are still in their infancy, finds a paper publishe

Updated on:May 08,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on: March 25,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on:March 25,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on: March 07,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on:March 07,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on: February 27,2024

Can slow walking speed in elderly signal Alzheimer's disease hallmarks?

by American Academy of NeurologyDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.How fast elderly people walk may be related to the amount of amyloid

Updated on:February 27,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on: February 03,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on:February 03,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on: June 20,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on:June 20,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on: March 13,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on:March 13,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on: May 22,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on:May 22,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on: March 30,2024

Understanding the role of microglia in Alzheimer's disease

by VIB (the Flanders Institute for Biotechnology)Illustration of the complex microglial AD genetics by cell-state profiles and driven by different Aβ pathologies. Credit:Nature Neuroscience

Updated on:March 30,2024

Alzheimer's trial screening data links high amyloid levels with early stage disease

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainThe first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer&#39

Updated on: April 20,2024

Alzheimer's trial screening data links high amyloid levels with early stage disease

by National Institutes of HealthPET scan of a human brain with Alzheimer's disease. Credit: public domainThe first published data from the Anti-Amyloid Treatment in Asymptomatic Alzheimer&#39

Updated on:April 20,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on: June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on:June 14,2024