A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on: March 28,2024

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on:March 28,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on: March 25,2024

A novel immunotherapy proves effective in animal models of multiple sclerosis

by Thomas Jefferson UniversityThe purified oligodendrocyte extracellular vesicles under an electron microscope. Credit: G. Casella et al., Science Translational Medicine (2020)Multiple sclerosis

Updated on:March 25,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on: May 22,2024

Amyloid is a less accurate marker for measuring severity, progression of Alzheimer's

by Perelman School of Medicine at the University of PennsylvaniaPET imaging using the radiotracers FDG and florbetapir to quantify cognitive decline in patients with Alzheimer’s disease (AD), mil

Updated on:May 22,2024

Targeted preventive measures for hip fracture are needed for persons with Alzheimer's disease

by University of Eastern FinlandThe hip fracture risk factors are generally similar among those with and without Alzheimer's disease, according to a recent study from the University of Easter

Updated on: March 07,2024

Targeted preventive measures for hip fracture are needed for persons with Alzheimer's disease

by University of Eastern FinlandThe hip fracture risk factors are generally similar among those with and without Alzheimer's disease, according to a recent study from the University of Easter

Updated on:March 07,2024

Recurrent brain trauma may increase Alzheimer's risk

by Radiological Society of North AmericaParametric maps of amyloid deposition in healthy control participants (A and B) and blast-exposed military instructors (C and D) at baseline (A and C) and

Updated on: June 01,2024

Recurrent brain trauma may increase Alzheimer's risk

by Radiological Society of North AmericaParametric maps of amyloid deposition in healthy control participants (A and B) and blast-exposed military instructors (C and D) at baseline (A and C) and

Updated on:June 01,2024

Alzheimer-type brain pathology after transplantation of dura mater

by University of ZurichBrown-colored A-beta plaques in the cerebral cortex in Alzheimer's disease. Credit: University Hospital ZurichUp to now Alzheimer's disease has not been recognized

Updated on: February 27,2024

Alzheimer-type brain pathology after transplantation of dura mater

by University of ZurichBrown-colored A-beta plaques in the cerebral cortex in Alzheimer's disease. Credit: University Hospital ZurichUp to now Alzheimer's disease has not been recognized

Updated on:February 27,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on: February 03,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on:February 03,2024

Alzheimer's genes might show effects in your 20s

by Alan MozesEvery college student misplaces keys or forgets an appointment from time to time. Usually it's no big deal. But a new study warns that when young people with a family history of Alzhe

Updated on: April 18,2024

Alzheimer's genes might show effects in your 20s

by Alan MozesEvery college student misplaces keys or forgets an appointment from time to time. Usually it's no big deal. But a new study warns that when young people with a family history of Alzhe

Updated on:April 18,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on: March 13,2024

5α-reductase inhibitors linked to depression, but not dementia

by Elana Gotkine HealthDay Reporter5α-reductase inhibitors (5-ARIs) are associated with an increased risk for depression but seem not to be associated with dementia, according to a study published onl

Updated on:March 13,2024

Exploring how astrocytes respond to spinal cord injury or stroke-induced tissue damage

by Ingrid Fadelli , Medical XpressWound repair astrocytes (in green) form a border around the inflammatory cells (in white) that invade an area of brain tissue damaged by a small stroke. This astrocyt

Updated on: July 31,2024

Exploring how astrocytes respond to spinal cord injury or stroke-induced tissue damage

by Ingrid Fadelli , Medical XpressWound repair astrocytes (in green) form a border around the inflammatory cells (in white) that invade an area of brain tissue damaged by a small stroke. This astrocyt

Updated on:July 31,2024

Multi-feature-based brain network improves auto-diagnosis of Alzheimer's disease

by ElsevierResearchers have developed a new method for constructing personal brain networks using multiple structural features to improve the accuracy of diagnosing Alzheimer's disease (AD) a

Updated on: March 07,2024

Multi-feature-based brain network improves auto-diagnosis of Alzheimer's disease

by ElsevierResearchers have developed a new method for constructing personal brain networks using multiple structural features to improve the accuracy of diagnosing Alzheimer's disease (AD) a

Updated on:March 07,2024