A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on: June 20,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on:June 20,2024

Nerve cells in the brain can halt all movement in the body—even breathing

JULY 29, 2023byUniversity of CopenhagenBrainstem projection targets from Chx10-PPN neurons. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01396-3When a hunting dog picks

Updated on: March 13,2024

Nerve cells in the brain can halt all movement in the body—even breathing

JULY 29, 2023byUniversity of CopenhagenBrainstem projection targets from Chx10-PPN neurons. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01396-3When a hunting dog picks

Updated on:March 13,2024

Pressure sensing by muscles provides a promising new target for treatments

by Michael Dimitriou,Umea UniversityCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114699A new study from Umeå University, Sweden, shows that the body's muscles sense mech

Updated on: September 23,2024

Pressure sensing by muscles provides a promising new target for treatments

by Michael Dimitriou,Umea UniversityCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114699A new study from Umeå University, Sweden, shows that the body's muscles sense mech

Updated on:September 23,2024

Alzheimer's research strengthens evidence for reanalyzing data in clinical trials that 'failed'

by Ellen Goldbaum,University at BuffaloCredit: Unsplash/CC0 Public DomainNew research on Alzheimer's disease led by the University at Buffalo reveals strong evidence that clinical trials on

Updated on: April 16,2024

Alzheimer's research strengthens evidence for reanalyzing data in clinical trials that 'failed'

by Ellen Goldbaum,University at BuffaloCredit: Unsplash/CC0 Public DomainNew research on Alzheimer's disease led by the University at Buffalo reveals strong evidence that clinical trials on

Updated on:April 16,2024

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on: March 28,2024

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on:March 28,2024

Alzheimer's disease protein links plaques to cell death in mice

by RIKENMRI scans of CAPON-overexpressing mouse brains scanned 7 days and 3 months after CAPON cDNA introduction to AD mice. Credit: RIKENA new protein involved in Alzheimer's disease (AD) ha

Updated on: April 07,2024

Alzheimer's disease protein links plaques to cell death in mice

by RIKENMRI scans of CAPON-overexpressing mouse brains scanned 7 days and 3 months after CAPON cDNA introduction to AD mice. Credit: RIKENA new protein involved in Alzheimer's disease (AD) ha

Updated on:April 07,2024

Exploring how astrocytes respond to spinal cord injury or stroke-induced tissue damage

by Ingrid Fadelli , Medical XpressWound repair astrocytes (in green) form a border around the inflammatory cells (in white) that invade an area of brain tissue damaged by a small stroke. This astrocyt

Updated on: July 31,2024

Exploring how astrocytes respond to spinal cord injury or stroke-induced tissue damage

by Ingrid Fadelli , Medical XpressWound repair astrocytes (in green) form a border around the inflammatory cells (in white) that invade an area of brain tissue damaged by a small stroke. This astrocyt

Updated on:July 31,2024

Use of feeding tubes decreases among nursing home residents with advanced dementia

by The JAMA Network JournalsIn a study appearing in the August 16 issue ofJAMA, Susan L. Mitchell, M.D., M.P.H., of Hebrew SeniorLife Institute for Aging Research, Harvard Medical School, B

Updated on: March 07,2024

Use of feeding tubes decreases among nursing home residents with advanced dementia

by The JAMA Network JournalsIn a study appearing in the August 16 issue ofJAMA, Susan L. Mitchell, M.D., M.P.H., of Hebrew SeniorLife Institute for Aging Research, Harvard Medical School, B

Updated on:March 07,2024

How to fast safely during Ramadan: What the science shows

by Feisal Subhan,The ConversationCredit: Pixabay/CC0 Public DomainFor1.9 billion Muslims, Ramadan is the ninth and holiest Islamic month and this year starts on March 11. During the 30 day

Updated on: March 19,2024

How to fast safely during Ramadan: What the science shows

by Feisal Subhan,The ConversationCredit: Pixabay/CC0 Public DomainFor1.9 billion Muslims, Ramadan is the ninth and holiest Islamic month and this year starts on March 11. During the 30 day

Updated on:March 19,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on: February 03,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on:February 03,2024

Care more expensive for dementia patients and families in last years of life

by The Mount Sinai HospitalThe cost of care over the last five years of life for patients with dementia is significantly higher than for patients who die from heart disease, cancer, or other caus

Updated on: February 26,2024

Care more expensive for dementia patients and families in last years of life

by The Mount Sinai HospitalThe cost of care over the last five years of life for patients with dementia is significantly higher than for patients who die from heart disease, cancer, or other caus

Updated on:February 26,2024