Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on: June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on:June 14,2024

Exploring how astrocytes respond to spinal cord injury or stroke-induced tissue damage

by Ingrid Fadelli , Medical XpressWound repair astrocytes (in green) form a border around the inflammatory cells (in white) that invade an area of brain tissue damaged by a small stroke. This astrocyt

Updated on: July 31,2024

Exploring how astrocytes respond to spinal cord injury or stroke-induced tissue damage

by Ingrid Fadelli , Medical XpressWound repair astrocytes (in green) form a border around the inflammatory cells (in white) that invade an area of brain tissue damaged by a small stroke. This astrocyt

Updated on:July 31,2024

Different biological variants discovered in Alzheimer's disease

by Amsterdam University Medical CenterCredit: Pixabay/CC0 Public DomainDutch scientists have discovered five biological variants of Alzheimer's disease, which may require different treatments. As

Updated on: February 24,2024

Different biological variants discovered in Alzheimer's disease

by Amsterdam University Medical CenterCredit: Pixabay/CC0 Public DomainDutch scientists have discovered five biological variants of Alzheimer's disease, which may require different treatments. As

Updated on:February 24,2024

Genomics- and image-guided subtyping refines characterization of Alzheimer's disease

by Society of Nuclear Medicine and Molecular ImagingRight and left hemisphere brain surface plots showing the strength of the canonical vector, νƙ, for each subtype. Credit: Images created by Fan Yang

Updated on: June 14,2024

Genomics- and image-guided subtyping refines characterization of Alzheimer's disease

by Society of Nuclear Medicine and Molecular ImagingRight and left hemisphere brain surface plots showing the strength of the canonical vector, νƙ, for each subtype. Credit: Images created by Fan Yang

Updated on:June 14,2024

How a common food ingredient can take a wrong turn, leading to arthritis

by Mark Harden,CU Anschutz Medical CampusGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI167671A University of Colorado Department of Medicine fac

Updated on: March 19,2024

How a common food ingredient can take a wrong turn, leading to arthritis

by Mark Harden,CU Anschutz Medical CampusGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI167671A University of Colorado Department of Medicine fac

Updated on:March 19,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on: February 03,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on:February 03,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on: October 16,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on:October 16,2024

Researchers find preclinical evidence that a nasal immunotherapy may help treat Alzheimer's disease

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainAlzheimer's is a debilitating neurodegenerative and neuroinflammatory disease that is difficult to treat. Most existing th

Updated on: March 02,2024

Researchers find preclinical evidence that a nasal immunotherapy may help treat Alzheimer's disease

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainAlzheimer's is a debilitating neurodegenerative and neuroinflammatory disease that is difficult to treat. Most existing th

Updated on:March 02,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on: February 03,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on:February 03,2024

Alzheimer's genes might show effects in your 20s

by Alan MozesEvery college student misplaces keys or forgets an appointment from time to time. Usually it's no big deal. But a new study warns that when young people with a family history of Alzhe

Updated on: April 18,2024

Alzheimer's genes might show effects in your 20s

by Alan MozesEvery college student misplaces keys or forgets an appointment from time to time. Usually it's no big deal. But a new study warns that when young people with a family history of Alzhe

Updated on:April 18,2024

New proteins involved in spinocerebellar ataxia provide insight into selective neuronal vulnerability

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit:Neuron(2022). DOI: 10.1016/j.neuron.2022.11.016Neurodegenerative disorders like Alzheimer's and Parkinson's

Updated on: February 05,2024

New proteins involved in spinocerebellar ataxia provide insight into selective neuronal vulnerability

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit:Neuron(2022). DOI: 10.1016/j.neuron.2022.11.016Neurodegenerative disorders like Alzheimer's and Parkinson's

Updated on:February 05,2024

Nerve cells in the brain can halt all movement in the body—even breathing

JULY 29, 2023byUniversity of CopenhagenBrainstem projection targets from Chx10-PPN neurons. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01396-3When a hunting dog picks

Updated on: March 13,2024

Nerve cells in the brain can halt all movement in the body—even breathing

JULY 29, 2023byUniversity of CopenhagenBrainstem projection targets from Chx10-PPN neurons. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01396-3When a hunting dog picks

Updated on:March 13,2024