A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Genomics- and image-guided subtyping refines characterization of Alzheimer's disease

by Society of Nuclear Medicine and Molecular ImagingRight and left hemisphere brain surface plots showing the strength of the canonical vector, νƙ, for each subtype. Credit: Images created by Fan Yang

Updated on: June 14,2024

Genomics- and image-guided subtyping refines characterization of Alzheimer's disease

by Society of Nuclear Medicine and Molecular ImagingRight and left hemisphere brain surface plots showing the strength of the canonical vector, νƙ, for each subtype. Credit: Images created by Fan Yang

Updated on:June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on: June 14,2024

Machine learning models rank predictive risks for Alzheimer's disease

by Emily Caldwell,The Ohio State UniversityFeature importance and impact of top 20 most important features for different age groups. SHAP global feature importance bar chart (left) and SHAP loca

Updated on:June 14,2024

Potential new treatment for Alzheimer's disease would be relatively cheap

by RIKENNeprilysin (red) and Aβ (green) levels in the hippocampus of Alzheimer's disease model mice. Top: control. Bottom: after being fed diazoxide. After diazoxide treatment, neprilysin lev

Updated on: April 07,2024

Potential new treatment for Alzheimer's disease would be relatively cheap

by RIKENNeprilysin (red) and Aβ (green) levels in the hippocampus of Alzheimer's disease model mice. Top: control. Bottom: after being fed diazoxide. After diazoxide treatment, neprilysin lev

Updated on:April 07,2024

Use of feeding tubes decreases among nursing home residents with advanced dementia

by The JAMA Network JournalsIn a study appearing in the August 16 issue ofJAMA, Susan L. Mitchell, M.D., M.P.H., of Hebrew SeniorLife Institute for Aging Research, Harvard Medical School, B

Updated on: March 07,2024

Use of feeding tubes decreases among nursing home residents with advanced dementia

by The JAMA Network JournalsIn a study appearing in the August 16 issue ofJAMA, Susan L. Mitchell, M.D., M.P.H., of Hebrew SeniorLife Institute for Aging Research, Harvard Medical School, B

Updated on:March 07,2024

Alzheimer-type brain pathology after transplantation of dura mater

by University of ZurichBrown-colored A-beta plaques in the cerebral cortex in Alzheimer's disease. Credit: University Hospital ZurichUp to now Alzheimer's disease has not been recognized

Updated on: February 27,2024

Alzheimer-type brain pathology after transplantation of dura mater

by University of ZurichBrown-colored A-beta plaques in the cerebral cortex in Alzheimer's disease. Credit: University Hospital ZurichUp to now Alzheimer's disease has not been recognized

Updated on:February 27,2024

Often overlooked stem cells hold hidden powers for blood disease treatments

by King Abdullah University of Science and TechnologyResearchers have identified a method to enhance the regenerative capabilities of stem cells found in umbilical cord blood, which could have be

Updated on: March 19,2024

Often overlooked stem cells hold hidden powers for blood disease treatments

by King Abdullah University of Science and TechnologyResearchers have identified a method to enhance the regenerative capabilities of stem cells found in umbilical cord blood, which could have be

Updated on:March 19,2024

Alzheimer's study: Drug combination improves memory skills in mice

by Elizabeth Hernandez, The Denver PostChanges in glial cell and neuronal numbers with Nanoligomer treatment in tauopathy mice. Credit:Journal of Neuroinflammation(2024). DOI: 10.1186/s129

Updated on: September 25,2024

Alzheimer's study: Drug combination improves memory skills in mice

by Elizabeth Hernandez, The Denver PostChanges in glial cell and neuronal numbers with Nanoligomer treatment in tauopathy mice. Credit:Journal of Neuroinflammation(2024). DOI: 10.1186/s129

Updated on:September 25,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on: February 03,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on:February 03,2024

Insurers balk at paying for Biogen's $56,000-a-year Alzheimer's treatment

by John Tozzi, Angelica Lavito and Anushree DaveCredit: CC0 Public DomainU.S. health insurers say they want more proof before paying for Biogen Inc.'s Aduhelm, stalling sales of the costly new Alz

Updated on: April 29,2024

Insurers balk at paying for Biogen's $56,000-a-year Alzheimer's treatment

by John Tozzi, Angelica Lavito and Anushree DaveCredit: CC0 Public DomainU.S. health insurers say they want more proof before paying for Biogen Inc.'s Aduhelm, stalling sales of the costly new Alz

Updated on:April 29,2024

A century after the EEG was discovered, it remains a crucial tool for understanding the brain

by Giridhar Kalamangalam,The ConversationCredit: Pixabay/CC0 Public DomainJena, Germany, 1924: Working in near-isolation and with painstaking tediousness, thepsychiatrist Hans Berger

Updated on: April 06,2024

A century after the EEG was discovered, it remains a crucial tool for understanding the brain

by Giridhar Kalamangalam,The ConversationCredit: Pixabay/CC0 Public DomainJena, Germany, 1924: Working in near-isolation and with painstaking tediousness, thepsychiatrist Hans Berger

Updated on:April 06,2024

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on: March 19,2024

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on:March 19,2024