First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on: March 30,2024

First 'gene silencing' drug for Alzheimer's disease shows promise

by University College LondonEffect of MAPTRxon CSF concentrations of p-tau protein and tau/Aβ42. a, The mean percentage change from baseline in p-tau over time according to dose group. b, T

Updated on:March 30,2024

Beyond plaques and tangles: Genetic variation may increase risk of cognitive decline

by American Academy of NeurologyCredit: CC0 Public DomainA genetic variation in some people may be associated with cognitive decline that can't be explained by deposits of two key proteins as

Updated on: May 13,2024

Beyond plaques and tangles: Genetic variation may increase risk of cognitive decline

by American Academy of NeurologyCredit: CC0 Public DomainA genetic variation in some people may be associated with cognitive decline that can't be explained by deposits of two key proteins as

Updated on:May 13,2024

Can the healthy brain offer clues to curing Alzheimer's?

by The ConversationImage of brain with regions of the medial temporal lobe colour-coded"Have you cured Alzheimer's disease yet?"This is a common question people ask when they discov

Updated on: June 24,2024

Can the healthy brain offer clues to curing Alzheimer's?

by The ConversationImage of brain with regions of the medial temporal lobe colour-coded"Have you cured Alzheimer's disease yet?"This is a common question people ask when they discov

Updated on:June 24,2024

Dementia leading cause of death in September

by Alzheimer's Research UKCredit: CC0 Public DomainThe Office for National Statistics (ONS) has today (23 October) revealed "dementia and Alzheimer's disease" were the leading c

Updated on: May 11,2024

Dementia leading cause of death in September

by Alzheimer's Research UKCredit: CC0 Public DomainThe Office for National Statistics (ONS) has today (23 October) revealed "dementia and Alzheimer's disease" were the leading c

Updated on:May 11,2024

From autism to Alzheimer's: A large-scale animal study links brain pH changes to wide-ranging cognitive issues

byFujita Health UniversityIncreased brain lactate levels correlated with decreased pH are associated with poor working memory. Credit: eLife (2024). DOI: 10.7554/eLife.89376.3A global collaborat

Updated on: March 28,2024

From autism to Alzheimer's: A large-scale animal study links brain pH changes to wide-ranging cognitive issues

byFujita Health UniversityIncreased brain lactate levels correlated with decreased pH are associated with poor working memory. Credit: eLife (2024). DOI: 10.7554/eLife.89376.3A global collaborat

Updated on:March 28,2024

Dementia and COVID: What families and physicians should know

by Columbia University Irving Medical CenterCredit: CC0 Public DomainEarly in the pandemic, neurologists expressed concern that COVID-19 patients with dementia may be at higher risk for complicat

Updated on: May 06,2024

Dementia and COVID: What families and physicians should know

by Columbia University Irving Medical CenterCredit: CC0 Public DomainEarly in the pandemic, neurologists expressed concern that COVID-19 patients with dementia may be at higher risk for complicat

Updated on:May 06,2024

Dopamine treatment found to alleviate symptoms in Alzheimer's disease

byRIKENImmunostaining of Aβ (Green) detected by N1D antibody from frontal cortices of 12-month-old AppNL-F; DAT-Cre mice infected with or without the viral vectors AAV8-hSyn-DIO-mCherry and AAV8

Updated on: August 08,2024

Dopamine treatment found to alleviate symptoms in Alzheimer's disease

byRIKENImmunostaining of Aβ (Green) detected by N1D antibody from frontal cortices of 12-month-old AppNL-F; DAT-Cre mice infected with or without the viral vectors AAV8-hSyn-DIO-mCherry and AAV8

Updated on:August 08,2024

Link found between chronic inflammation and risk for Alzheimer's disease

by Boston University School of MedicineWhile it is widely shown that possessing the ApoE4 gene is the major genetic risk factor of Alzheimer's disease (AD), not all ApoE4 carriers develop AD.

Updated on: March 07,2024

Link found between chronic inflammation and risk for Alzheimer's disease

by Boston University School of MedicineWhile it is widely shown that possessing the ApoE4 gene is the major genetic risk factor of Alzheimer's disease (AD), not all ApoE4 carriers develop AD.

Updated on:March 07,2024

Brain's 'appetite control center' found to be different in people who are overweight or living with obesity

by University of CambridgeCredit: CC0 Public DomainCambridge scientists have shown that the hypothalamus, a key region of the brain involved in controlling appetite, is different in the brains of

Updated on: February 05,2024

Brain's 'appetite control center' found to be different in people who are overweight or living with obesity

by University of CambridgeCredit: CC0 Public DomainCambridge scientists have shown that the hypothalamus, a key region of the brain involved in controlling appetite, is different in the brains of

Updated on:February 05,2024

Can brain stimulation improve memory formation?

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainFor some adults, the use of a responsive neurostimulation (RNS) system implanted in the brain can help lessen or

Updated on: February 21,2024

Can brain stimulation improve memory formation?

by Graciela Gutierrez,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainFor some adults, the use of a responsive neurostimulation (RNS) system implanted in the brain can help lessen or

Updated on:February 21,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on: February 03,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on:February 03,2024

Researchers identify three genes associated with neurodevelopmental disorders

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI171235An international study group led by researchers of

Updated on: June 19,2024

Researchers identify three genes associated with neurodevelopmental disorders

by Children's Hospital of PhiladelphiaGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI171235An international study group led by researchers of

Updated on:June 19,2024