Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on: July 31,2024

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on:July 31,2024

Exercise alters brain chemistry to protect aging synapses

by University of California, San FranciscoCredit: Unsplash/CC0 Public DomainWhen elderly people stay active, their brains have more of a class of proteins that enhances the connections between ne

Updated on: May 22,2024

Exercise alters brain chemistry to protect aging synapses

by University of California, San FranciscoCredit: Unsplash/CC0 Public DomainWhen elderly people stay active, their brains have more of a class of proteins that enhances the connections between ne

Updated on:May 22,2024

New perspectives on understanding, preventing and treating vascular dementia

by Hôpitaux Universitaires de GenèveCCR5 expression in response to oxidative stress is mediated by NF-κB. (A)Upper: Schematic overview of the murineCcr5gene. Blue boxes represent int

Updated on: March 02,2024

New perspectives on understanding, preventing and treating vascular dementia

by Hôpitaux Universitaires de GenèveCCR5 expression in response to oxidative stress is mediated by NF-κB. (A)Upper: Schematic overview of the murineCcr5gene. Blue boxes represent int

Updated on:March 02,2024

Large collaboration yields unprecedented 'live' view into the brain's complexity

by Institute of Science and Technology AustriaLIONESS delineates the complexity of dense brain tissue. a: Complex neuronal environment b: LIONESS can image and reconstruct the sample in a way tha

Updated on: February 18,2024

Large collaboration yields unprecedented 'live' view into the brain's complexity

by Institute of Science and Technology AustriaLIONESS delineates the complexity of dense brain tissue. a: Complex neuronal environment b: LIONESS can image and reconstruct the sample in a way tha

Updated on:February 18,2024

Elon Musk's brain implant company offers an intriguing glimpse of an internet connecting human minds

by Simon Marvin and Allan McCay,The ConversationCredit: Rice UniversityElon Musk'scompany called Neuralink, launched in 2016, aims toimplant a piece of technologyin people&

Updated on: March 28,2024

Elon Musk's brain implant company offers an intriguing glimpse of an internet connecting human minds

by Simon Marvin and Allan McCay,The ConversationCredit: Rice UniversityElon Musk'scompany called Neuralink, launched in 2016, aims toimplant a piece of technologyin people&

Updated on:March 28,2024

Alzheimer's drug trial shows 'evidence of sustained improvement'

by University of AberdeenRelationship between steady-state plasma levels of hydromethylthionine and decline on the ADAS-Cog11scale over 65 weeks in 566 participants receiving hydromethylthi

Updated on: April 16,2024

Alzheimer's drug trial shows 'evidence of sustained improvement'

by University of AberdeenRelationship between steady-state plasma levels of hydromethylthionine and decline on the ADAS-Cog11scale over 65 weeks in 566 participants receiving hydromethylthi

Updated on:April 16,2024

Do veterans who experience concussions have an increased risk of Alzheimer's?

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainMiddle-age veterans who experienced concussions due to blasts from explosive devices may have biomarkers in their spinal fluid sim

Updated on: March 19,2024

Do veterans who experience concussions have an increased risk of Alzheimer's?

by American Academy of NeurologyCredit: Pixabay/CC0 Public DomainMiddle-age veterans who experienced concussions due to blasts from explosive devices may have biomarkers in their spinal fluid sim

Updated on:March 19,2024

Personality changes during transition to developing mild cognitive impairment

by American Geriatrics SocietyA key feature of Alzheimer's disease is memory loss and losing one's ability to think and make decisions (also called "cognitive ability"). Those c

Updated on: March 07,2024

Personality changes during transition to developing mild cognitive impairment

by American Geriatrics SocietyA key feature of Alzheimer's disease is memory loss and losing one's ability to think and make decisions (also called "cognitive ability"). Those c

Updated on:March 07,2024

New proteins involved in spinocerebellar ataxia provide insight into selective neuronal vulnerability

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit:Neuron(2022). DOI: 10.1016/j.neuron.2022.11.016Neurodegenerative disorders like Alzheimer's and Parkinson's

Updated on: February 05,2024

New proteins involved in spinocerebellar ataxia provide insight into selective neuronal vulnerability

by Molly Chiu,Baylor College of MedicineGraphical abstract. Credit:Neuron(2022). DOI: 10.1016/j.neuron.2022.11.016Neurodegenerative disorders like Alzheimer's and Parkinson's

Updated on:February 05,2024

BACE-Inhibitor successfully tested in Alzheimer's animal model

by Technical University MunichMarc Aurel Busche at the two-photon microscope, which allows to visualize nerve cells with high temporal and spatial resolution in the intact brain. Credit: Kurt Bau

Updated on: March 19,2024

BACE-Inhibitor successfully tested in Alzheimer's animal model

by Technical University MunichMarc Aurel Busche at the two-photon microscope, which allows to visualize nerve cells with high temporal and spatial resolution in the intact brain. Credit: Kurt Bau

Updated on:March 19,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on: February 03,2024

Sprint then stop? Brain is wired for the math to make it happen

by Massachusetts Institute of TechnologyRed ("mCherry") staining highlights axonal projections from the motor cortex M2. Of particular importance are ones leading to the subthalamic nuc

Updated on:February 03,2024

Alzheimer's risk gene undermines insulation of brain's 'wiring'

by Massachusetts Institute of TechnologyBlack gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4

Updated on: April 20,2024

Alzheimer's risk gene undermines insulation of brain's 'wiring'

by Massachusetts Institute of TechnologyBlack gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4

Updated on:April 20,2024