Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Portable cap can measure cognition with pulsed laser light

by Anne McGovern,Massachusetts Institute of TechnologyFour custom readout integrated circuits are mounted so that they can be placed on metal plating. The Geiger-mode avalanche photodiodes are l

Updated on: February 05,2024

Portable cap can measure cognition with pulsed laser light

by Anne McGovern,Massachusetts Institute of TechnologyFour custom readout integrated circuits are mounted so that they can be placed on metal plating. The Geiger-mode avalanche photodiodes are l

Updated on:February 05,2024

Researchers introduce enhanced brain signal analysis technique

by Alex Smith,University of Minnesota Medical SchoolReplication of previous results using a predefined time window. (A) Proportion of channels whose ERP signals’ significance were labeled the sa

Updated on: March 30,2024

Researchers introduce enhanced brain signal analysis technique

by Alex Smith,University of Minnesota Medical SchoolReplication of previous results using a predefined time window. (A) Proportion of channels whose ERP signals’ significance were labeled the sa

Updated on:March 30,2024

Getting the temperature just right helps people with dementia stay cool

by Paul Cooper, Federico Tartarini And Richard Fleming,The ConversationDr Federico Tartarini (right) led the study that found that indoor temperatures in aged care centres have a dramatic impact

Updated on: April 29,2024

Getting the temperature just right helps people with dementia stay cool

by Paul Cooper, Federico Tartarini And Richard Fleming,The ConversationDr Federico Tartarini (right) led the study that found that indoor temperatures in aged care centres have a dramatic impact

Updated on:April 29,2024

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on: March 19,2024

Genome-wide transcriptome profiling and development of age prediction models in the human brain

by Impact Journals LLCDifferential gene expression analysis overall and by sex. Credit:Aging(2024). DOI: 10.18632/aging.205609A new research paper was published inAgingentitled

Updated on:March 19,2024

Potential new treatment for Alzheimer's disease would be relatively cheap

by RIKENNeprilysin (red) and Aβ (green) levels in the hippocampus of Alzheimer's disease model mice. Top: control. Bottom: after being fed diazoxide. After diazoxide treatment, neprilysin lev

Updated on: April 07,2024

Potential new treatment for Alzheimer's disease would be relatively cheap

by RIKENNeprilysin (red) and Aβ (green) levels in the hippocampus of Alzheimer's disease model mice. Top: control. Bottom: after being fed diazoxide. After diazoxide treatment, neprilysin lev

Updated on:April 07,2024

Targeted preventive measures for hip fracture are needed for persons with Alzheimer's disease

by University of Eastern FinlandThe hip fracture risk factors are generally similar among those with and without Alzheimer's disease, according to a recent study from the University of Easter

Updated on: March 07,2024

Targeted preventive measures for hip fracture are needed for persons with Alzheimer's disease

by University of Eastern FinlandThe hip fracture risk factors are generally similar among those with and without Alzheimer's disease, according to a recent study from the University of Easter

Updated on:March 07,2024

Converting brain immune cells into neurons helps mice recover after stroke

by Kyushu UniversityProduction of NeuroD1 in microglial cells induces their development into neurons, therefore decreasing the area of the brain with neuron loss. In scans of the mice brains, neurons

Updated on: January 12,2024

Converting brain immune cells into neurons helps mice recover after stroke

by Kyushu UniversityProduction of NeuroD1 in microglial cells induces their development into neurons, therefore decreasing the area of the brain with neuron loss. In scans of the mice brains, neurons

Updated on:January 12,2024

Gene ID'd as potential therapeutic target for dementia in Parkinson's

by Washington University School of MedicineClumps of the Parkinson's protein alpha-synuclein (red) are visible inside neurons (green) in the brain of a mouse. Researchers at Washington Univer

Updated on: June 14,2024

Gene ID'd as potential therapeutic target for dementia in Parkinson's

by Washington University School of MedicineClumps of the Parkinson's protein alpha-synuclein (red) are visible inside neurons (green) in the brain of a mouse. Researchers at Washington Univer

Updated on:June 14,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on: June 24,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on:June 24,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on: June 18,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on:June 18,2024

People living with dementia boosted by new guide to care

by Flinders UniversityCredit: Flinders UniversityPeople with dementia and their carers can ask for the care they deserve with confidence after the launch of a new guide to their care rights.The C

Updated on: May 08,2024

People living with dementia boosted by new guide to care

by Flinders UniversityCredit: Flinders UniversityPeople with dementia and their carers can ask for the care they deserve with confidence after the launch of a new guide to their care rights.The C

Updated on:May 08,2024