Gout strongly associated with reduced gray matter and increased neurodegenerative disease

by Justin Jackson , Medical XpressDifferences in regional gray matter volume between participants with gout (n = 1,165) and controls (n = 32,202), as analyzed by voxel-based morphometry. Blue regions

Updated on: May 13,2024

Gout strongly associated with reduced gray matter and increased neurodegenerative disease

by Justin Jackson , Medical XpressDifferences in regional gray matter volume between participants with gout (n = 1,165) and controls (n = 32,202), as analyzed by voxel-based morphometry. Blue regions

Updated on:May 13,2024

Alzheimer's research strengthens evidence for reanalyzing data in clinical trials that 'failed'

by Ellen Goldbaum,University at BuffaloCredit: Unsplash/CC0 Public DomainNew research on Alzheimer's disease led by the University at Buffalo reveals strong evidence that clinical trials on

Updated on: April 16,2024

Alzheimer's research strengthens evidence for reanalyzing data in clinical trials that 'failed'

by Ellen Goldbaum,University at BuffaloCredit: Unsplash/CC0 Public DomainNew research on Alzheimer's disease led by the University at Buffalo reveals strong evidence that clinical trials on

Updated on:April 16,2024

Alzheimer's disease protein links plaques to cell death in mice

by RIKENMRI scans of CAPON-overexpressing mouse brains scanned 7 days and 3 months after CAPON cDNA introduction to AD mice. Credit: RIKENA new protein involved in Alzheimer's disease (AD) ha

Updated on: April 07,2024

Alzheimer's disease protein links plaques to cell death in mice

by RIKENMRI scans of CAPON-overexpressing mouse brains scanned 7 days and 3 months after CAPON cDNA introduction to AD mice. Credit: RIKENA new protein involved in Alzheimer's disease (AD) ha

Updated on:April 07,2024

Researchers find enzyme plays much larger role in preventing neurodegenerative diseases

JANUARY 31, 2024byIndiana UniversityDeleting NMNAT2 in cortical glutamatergic neurons results in age-dependent axonal degeneration.ABody weight of cKO and their littermate control (c

Updated on: March 28,2024

Researchers find enzyme plays much larger role in preventing neurodegenerative diseases

JANUARY 31, 2024byIndiana UniversityDeleting NMNAT2 in cortical glutamatergic neurons results in age-dependent axonal degeneration.ABody weight of cKO and their littermate control (c

Updated on:March 28,2024

Expert offers perspective on experimental Alzheimer's disease drug

by Deb BalzerCredit: Pixabay/CC0 Public DomainAccording to drugmakers Eisai and Biogen, a Phase 3 clinical study on a potential new Alzheimer's disease drug shows promise. The study findings show

Updated on: April 18,2024

Expert offers perspective on experimental Alzheimer's disease drug

by Deb BalzerCredit: Pixabay/CC0 Public DomainAccording to drugmakers Eisai and Biogen, a Phase 3 clinical study on a potential new Alzheimer's disease drug shows promise. The study findings show

Updated on:April 18,2024

Portable cap can measure cognition with pulsed laser light

by Anne McGovern,Massachusetts Institute of TechnologyFour custom readout integrated circuits are mounted so that they can be placed on metal plating. The Geiger-mode avalanche photodiodes are l

Updated on: February 05,2024

Portable cap can measure cognition with pulsed laser light

by Anne McGovern,Massachusetts Institute of TechnologyFour custom readout integrated circuits are mounted so that they can be placed on metal plating. The Geiger-mode avalanche photodiodes are l

Updated on:February 05,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on: June 24,2024

Identification of potential target protein aggregates for treating Alzheimer's

by CEACredit: CC0 Public DomainThe aggregation of alpha-synuclein proteins in Parkinson's disease and tau proteins in Alzheimer's disease is intimately linked to the progression of these neuro

Updated on:June 24,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on: October 16,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on:October 16,2024

Brain vesicles found to contain selectively packaged, full-length mRNA

by Sanford-Burnham PrebysThis portrait of extracellular vesicles was taken using confocal laser scanning microscopy. The membrane was stained with fluorescent dye. Image titled"Exosome

Updated on: April 28,2024

Brain vesicles found to contain selectively packaged, full-length mRNA

by Sanford-Burnham PrebysThis portrait of extracellular vesicles was taken using confocal laser scanning microscopy. The membrane was stained with fluorescent dye. Image titled"Exosome

Updated on:April 28,2024

Repeated infections associated with increased risk of some neurodegenerative diseases

by Public Library of ScienceResearchers assess hospital-treated infection and risk of neurodegenerative diseases. Created with Adobe Illustrator. Credit: Jiangwei Sun (CC-BY 4.0, creativecommons.

Updated on: June 01,2024

Repeated infections associated with increased risk of some neurodegenerative diseases

by Public Library of ScienceResearchers assess hospital-treated infection and risk of neurodegenerative diseases. Created with Adobe Illustrator. Credit: Jiangwei Sun (CC-BY 4.0, creativecommons.

Updated on:June 01,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

How to fast safely during Ramadan: What the science shows

by Feisal Subhan,The ConversationCredit: Pixabay/CC0 Public DomainFor1.9 billion Muslims, Ramadan is the ninth and holiest Islamic month and this year starts on March 11. During the 30 day

Updated on: March 19,2024

How to fast safely during Ramadan: What the science shows

by Feisal Subhan,The ConversationCredit: Pixabay/CC0 Public DomainFor1.9 billion Muslims, Ramadan is the ninth and holiest Islamic month and this year starts on March 11. During the 30 day

Updated on:March 19,2024