'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on: April 23,2024

'New' ALS gene destabilizes neuron's structure and chokes off its nucleus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainThe viral ALS Ice Bucket Challenge a few years ago raised major funding that resulted in the discovery of new genes connected to the dis

Updated on:April 23,2024

Researchers find enzyme plays much larger role in preventing neurodegenerative diseases

JANUARY 31, 2024byIndiana UniversityDeleting NMNAT2 in cortical glutamatergic neurons results in age-dependent axonal degeneration.ABody weight of cKO and their littermate control (c

Updated on: March 28,2024

Researchers find enzyme plays much larger role in preventing neurodegenerative diseases

JANUARY 31, 2024byIndiana UniversityDeleting NMNAT2 in cortical glutamatergic neurons results in age-dependent axonal degeneration.ABody weight of cKO and their littermate control (c

Updated on:March 28,2024

Targeted preventive measures for hip fracture are needed for persons with Alzheimer's disease

by University of Eastern FinlandThe hip fracture risk factors are generally similar among those with and without Alzheimer's disease, according to a recent study from the University of Easter

Updated on: March 07,2024

Targeted preventive measures for hip fracture are needed for persons with Alzheimer's disease

by University of Eastern FinlandThe hip fracture risk factors are generally similar among those with and without Alzheimer's disease, according to a recent study from the University of Easter

Updated on:March 07,2024

Large collaboration yields unprecedented 'live' view into the brain's complexity

by Institute of Science and Technology AustriaLIONESS delineates the complexity of dense brain tissue. a: Complex neuronal environment b: LIONESS can image and reconstruct the sample in a way tha

Updated on: February 18,2024

Large collaboration yields unprecedented 'live' view into the brain's complexity

by Institute of Science and Technology AustriaLIONESS delineates the complexity of dense brain tissue. a: Complex neuronal environment b: LIONESS can image and reconstruct the sample in a way tha

Updated on:February 18,2024

Alzheimer's disease protein links plaques to cell death in mice

by RIKENMRI scans of CAPON-overexpressing mouse brains scanned 7 days and 3 months after CAPON cDNA introduction to AD mice. Credit: RIKENA new protein involved in Alzheimer's disease (AD) ha

Updated on: April 07,2024

Alzheimer's disease protein links plaques to cell death in mice

by RIKENMRI scans of CAPON-overexpressing mouse brains scanned 7 days and 3 months after CAPON cDNA introduction to AD mice. Credit: RIKENA new protein involved in Alzheimer's disease (AD) ha

Updated on:April 07,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on: July 31,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on:July 31,2024

Genetic and non-genetic resilience against memory decline and Alzheimer's

by Alzheimer's Research UKResearchers across the world are keen to understand why some people experience memory decline or diseases like Alzheimer's, while others don't. At AAIC2016,

Updated on: March 07,2024

Genetic and non-genetic resilience against memory decline and Alzheimer's

by Alzheimer's Research UKResearchers across the world are keen to understand why some people experience memory decline or diseases like Alzheimer's, while others don't. At AAIC2016,

Updated on:March 07,2024

Often overlooked stem cells hold hidden powers for blood disease treatments

by King Abdullah University of Science and TechnologyResearchers have identified a method to enhance the regenerative capabilities of stem cells found in umbilical cord blood, which could have be

Updated on: March 19,2024

Often overlooked stem cells hold hidden powers for blood disease treatments

by King Abdullah University of Science and TechnologyResearchers have identified a method to enhance the regenerative capabilities of stem cells found in umbilical cord blood, which could have be

Updated on:March 19,2024

Portable cap can measure cognition with pulsed laser light

by Anne McGovern,Massachusetts Institute of TechnologyFour custom readout integrated circuits are mounted so that they can be placed on metal plating. The Geiger-mode avalanche photodiodes are l

Updated on: February 05,2024

Portable cap can measure cognition with pulsed laser light

by Anne McGovern,Massachusetts Institute of TechnologyFour custom readout integrated circuits are mounted so that they can be placed on metal plating. The Geiger-mode avalanche photodiodes are l

Updated on:February 05,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

Time until dementia symptoms appear can be estimated via brain scan

by Tamara Bhandari,Washington University School of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Washington University School of Medicine in St. Louis have developed an approach to est

Updated on: May 11,2024

Time until dementia symptoms appear can be estimated via brain scan

by Tamara Bhandari,Washington University School of MedicineCredit: Pixabay/CC0 Public DomainResearchers at Washington University School of Medicine in St. Louis have developed an approach to est

Updated on:May 11,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024