A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on: July 31,2024

Research reveals link between spinal muscular atrophy and liver damage

byAgency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI173702An international study has

Updated on:July 31,2024

Tactile imagery used to improve rehabilitation of patients with motor disorders

by Skolkovo Institute of Science and TechnologyBrain MRI projection. Credit: SkoltechSkoltech researchers in collaboration with Immanuel Kant Baltic Federal University, Lomonosov Moscow State Uni

Updated on: February 05,2024

Tactile imagery used to improve rehabilitation of patients with motor disorders

by Skolkovo Institute of Science and TechnologyBrain MRI projection. Credit: SkoltechSkoltech researchers in collaboration with Immanuel Kant Baltic Federal University, Lomonosov Moscow State Uni

Updated on:February 05,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on: March 02,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on:March 02,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on: April 25,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on:April 25,2024

Dementia leading cause of death in September

by Alzheimer's Research UKCredit: CC0 Public DomainThe Office for National Statistics (ONS) has today (23 October) revealed "dementia and Alzheimer's disease" were the leading c

Updated on: May 11,2024

Dementia leading cause of death in September

by Alzheimer's Research UKCredit: CC0 Public DomainThe Office for National Statistics (ONS) has today (23 October) revealed "dementia and Alzheimer's disease" were the leading c

Updated on:May 11,2024

Alzheimer's drug trial shows 'evidence of sustained improvement'

by University of AberdeenRelationship between steady-state plasma levels of hydromethylthionine and decline on the ADAS-Cog11scale over 65 weeks in 566 participants receiving hydromethylthi

Updated on: April 16,2024

Alzheimer's drug trial shows 'evidence of sustained improvement'

by University of AberdeenRelationship between steady-state plasma levels of hydromethylthionine and decline on the ADAS-Cog11scale over 65 weeks in 566 participants receiving hydromethylthi

Updated on:April 16,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on: March 02,2024

New link between increased astrocytes in the brain and blood in early Alzheimer's disease

by Karolinska InstitutetBrain regions with increased astrocytes that can appear in the blood. Credit: Konstantinos ChiotisA new study shows that the activation of the brain's immune defense c

Updated on:March 02,2024

Experts explore new approach to vaccine trials and pandemic preparedness

byUniversity of CologneExemplary setup of a VACCELERATE APT on vaccines. Credit:Infection(2024). DOI: 10.1007/s15010-024-02347-1An international consortium of experts led by Translat

Updated on: August 01,2024

Experts explore new approach to vaccine trials and pandemic preparedness

byUniversity of CologneExemplary setup of a VACCELERATE APT on vaccines. Credit:Infection(2024). DOI: 10.1007/s15010-024-02347-1An international consortium of experts led by Translat

Updated on:August 01,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

How brain circuits switch between different behaviors

by Weizmann Institute of ScienceSet-up and behavioral task. a, The experimental set-up. Bats flew in pairs and alternated between two behavioral modes: solo (left) and cross-over (right). b, Exam

Updated on: February 21,2024

How brain circuits switch between different behaviors

by Weizmann Institute of ScienceSet-up and behavioral task. a, The experimental set-up. Bats flew in pairs and alternated between two behavioral modes: solo (left) and cross-over (right). b, Exam

Updated on:February 21,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on: March 28,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on:March 28,2024