Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on: March 07,2024

Nicotinic acetylcholine receptors in the pathophysiology of Alzheimer's disease

by Bentham Science PublishersNicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due

Updated on:March 07,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on: March 13,2024

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on:March 13,2024

Portable cap can measure cognition with pulsed laser light

by Anne McGovern,Massachusetts Institute of TechnologyFour custom readout integrated circuits are mounted so that they can be placed on metal plating. The Geiger-mode avalanche photodiodes are l

Updated on: February 05,2024

Portable cap can measure cognition with pulsed laser light

by Anne McGovern,Massachusetts Institute of TechnologyFour custom readout integrated circuits are mounted so that they can be placed on metal plating. The Geiger-mode avalanche photodiodes are l

Updated on:February 05,2024

Brain modeling identifies circuits implicated in consciousness

by Human Brain ProjectResponse differences in brain circuits when broadcasting (top row) or receiving signals (bottom row). Left: healthy controls; Middle: unresponsive wakefulness; Right: minimally c

Updated on: February 21,2024

Brain modeling identifies circuits implicated in consciousness

by Human Brain ProjectResponse differences in brain circuits when broadcasting (top row) or receiving signals (bottom row). Left: healthy controls; Middle: unresponsive wakefulness; Right: minimally c

Updated on:February 21,2024

Trials reveal that internet-based conversations help sustain brain function in older adults

by Brian Burns,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainSocial isolation has been linked to faster cognitive decline and an increased risk of developing dementia, although

Updated on: April 28,2024

Trials reveal that internet-based conversations help sustain brain function in older adults

by Brian Burns,Massachusetts General HospitalCredit: Pixabay/CC0 Public DomainSocial isolation has been linked to faster cognitive decline and an increased risk of developing dementia, although

Updated on:April 28,2024

Genetic and non-genetic resilience against memory decline and Alzheimer's

by Alzheimer's Research UKResearchers across the world are keen to understand why some people experience memory decline or diseases like Alzheimer's, while others don't. At AAIC2016,

Updated on: March 07,2024

Genetic and non-genetic resilience against memory decline and Alzheimer's

by Alzheimer's Research UKResearchers across the world are keen to understand why some people experience memory decline or diseases like Alzheimer's, while others don't. At AAIC2016,

Updated on:March 07,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on: March 02,2024

Protein experts show altered ubiquitin signaling induces hallmarks of sporadic Alzheimer's disease

by Technion - Israel Institute of TechnologyUBB+1accumulates in the early stages of AD postmortem tissue.aImmunofluorescence staining of human tissue (ER = hippocampal complex,

Updated on:March 02,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on: March 13,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on:March 13,2024

Newly discovered mechanism in mitochondria could lead to new treatment for muscle disorders

byUniversity of CopenhagenCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-54183-4Researchers have discovered a mechanism in our cells that is essential to energy producti

Updated on: December 23,2024

Newly discovered mechanism in mitochondria could lead to new treatment for muscle disorders

byUniversity of CopenhagenCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-54183-4Researchers have discovered a mechanism in our cells that is essential to energy producti

Updated on:December 23,2024

From 'demented' to 'person with dementia': how and why the language of disability changed

by Roland Sussex,The ConversationThe initial aim of political correctness, to establish non-hateful language was, and still is, admirable. Credit: Nathan Anderson/UnsplashIn the second half of t

Updated on: May 13,2024

From 'demented' to 'person with dementia': how and why the language of disability changed

by Roland Sussex,The ConversationThe initial aim of political correctness, to establish non-hateful language was, and still is, admirable. Credit: Nathan Anderson/UnsplashIn the second half of t

Updated on:May 13,2024

More sunshine as a baby linked to less disease activity for children with multiple sclerosis

Updated on: March 05,2025

More sunshine as a baby linked to less disease activity for children with multiple sclerosis

Updated on:March 05,2025

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on: October 16,2024

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on:October 16,2024