Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on: March 28,2024

Study finds non-immune brain cells can acquire immune memory, may drive CNS pathologies like multiple sclerosis

byBrigham and Women’s Hospitalp300 promotes astrocyte epigenetic memory in EAE.a, Immunostaining (left) and quantification (right) of H3K27ac+and p300+astrocytes in mice with o

Updated on:March 28,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on: June 20,2024

Genetic 'hotspots' that speed up and slow down brain aging could provide new targets for Alzheimer's drugs

by University of Southern CaliforniaCredit: CC0 Public DomainResearchers from a USC-led consortium have discovered 15 "hotspots" in the genome that either speed up brain aging or slow i

Updated on:June 20,2024

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on: January 15,2025

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on:January 15,2025

How a gene for obesity affects the brain

byUniversity of MichiganPVHSH2B1→DRN neurocircuit inhibits food intake and obesity. Credit:Advanced Science(2024). DOI: 10.1002/advs.202400437Obesity is a complicated condition, caus

Updated on: July 17,2024

How a gene for obesity affects the brain

byUniversity of MichiganPVHSH2B1→DRN neurocircuit inhibits food intake and obesity. Credit:Advanced Science(2024). DOI: 10.1002/advs.202400437Obesity is a complicated condition, caus

Updated on:July 17,2024

Pressure sensing by muscles provides a promising new target for treatments

by Michael Dimitriou,Umea UniversityCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114699A new study from Umeå University, Sweden, shows that the body's muscles sense mech

Updated on: September 23,2024

Pressure sensing by muscles provides a promising new target for treatments

by Michael Dimitriou,Umea UniversityCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114699A new study from Umeå University, Sweden, shows that the body's muscles sense mech

Updated on:September 23,2024

Alzheimer's risk gene undermines insulation of brain's 'wiring'

by Massachusetts Institute of TechnologyBlack gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4

Updated on: April 20,2024

Alzheimer's risk gene undermines insulation of brain's 'wiring'

by Massachusetts Institute of TechnologyBlack gold staining in postmortem human brain samples from three individuals reveals significantly less myelination in people carrying a copy of the APOE4

Updated on:April 20,2024

The brain applies data compression for decision-making

by Champalimaud Centre for the UnknownGeorge Costanza's Frogger arcade videogame from the episode The Frogger of the sitcom Seinfeld. Exhibition Seinfeld: The Apartment, 451 W 14th Street, Manhatt

Updated on: February 21,2024

The brain applies data compression for decision-making

by Champalimaud Centre for the UnknownGeorge Costanza's Frogger arcade videogame from the episode The Frogger of the sitcom Seinfeld. Exhibition Seinfeld: The Apartment, 451 W 14th Street, Manhatt

Updated on:February 21,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on: February 03,2024

Traumatic brain injury may up risk for developing comorbidities

Traumatic brain injury (TBI) of any severity is associated with increased risk of chronic cardiovascular, endocrine, and neurologic comorbidities, according to a study published online April 28 in&nbs

Updated on:February 03,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on: March 28,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on:March 28,2024

Video streaming from ambulance can be life-changing for acute stroke patients

byChalmers University of TechnologyUsing video streaming and consultation in the ambulance, stroke patients can quickly and remotely be assessed by a neurologist and driven directly to the hospi

Updated on: October 18,2024

Video streaming from ambulance can be life-changing for acute stroke patients

byChalmers University of TechnologyUsing video streaming and consultation in the ambulance, stroke patients can quickly and remotely be assessed by a neurologist and driven directly to the hospi

Updated on:October 18,2024

Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on: May 18,2024

Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on:May 18,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on: March 02,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on:March 02,2024