Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on: March 02,2024

Antibody therapy inspired by patient case reduces tau tangles in a preclinical model of Alzheimer's disease

by Mass General BrighamCredit: Pixabay/Pete Linforth.A team led by researchers from Mass General Brigham reports promising results for a monoclonal antibody that takes aim at a new target for Alz

Updated on:March 02,2024

Silent synapses are abundant in the adult brain

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT neuroscientists have discovered that the adult brain contains millions of "silent synapses"—im

Updated on: February 05,2024

Silent synapses are abundant in the adult brain

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT neuroscientists have discovered that the adult brain contains millions of "silent synapses"—im

Updated on:February 05,2024

The brain applies data compression for decision-making

by Champalimaud Centre for the UnknownGeorge Costanza's Frogger arcade videogame from the episode The Frogger of the sitcom Seinfeld. Exhibition Seinfeld: The Apartment, 451 W 14th Street, Manhatt

Updated on: February 21,2024

The brain applies data compression for decision-making

by Champalimaud Centre for the UnknownGeorge Costanza's Frogger arcade videogame from the episode The Frogger of the sitcom Seinfeld. Exhibition Seinfeld: The Apartment, 451 W 14th Street, Manhatt

Updated on:February 21,2024

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on: October 16,2024

Global effort to map the human brain releases first data

byAllen Institute for Brain ScienceBrain slice being prepared for analysis and study. Credit: Erik Dinnel / Allen InstituteThe BRAIN Initiative Cell Atlas Network (BICAN) has launched its first

Updated on:October 16,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on: March 28,2024

Researchers report on the effectiveness of skin biopsy to detect Parkinson's and related neurodegenerative diseases

byBeth Israel Deaconess Medical CenterCredit: Pixabay/CC0 Public DomainIn a paper published in theJournal of the American Medical Association(JAMA), neurologists at Beth Israel Deaco

Updated on:March 28,2024

Team succeeds in determining the exact moment when the brain detects another person's gaze direction

byUniversity of GenevaExperimental paradigm and stimuli. Credit:NeuroImage(2024). DOI: 10.1016/j.neuroimage.2024.120659The gaze plays a central role in everyday social interactions.

Updated on: July 05,2024

Team succeeds in determining the exact moment when the brain detects another person's gaze direction

byUniversity of GenevaExperimental paradigm and stimuli. Credit:NeuroImage(2024). DOI: 10.1016/j.neuroimage.2024.120659The gaze plays a central role in everyday social interactions.

Updated on:July 05,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on: July 05,2024

Discovery of cellular mechanism to maintain brain's energy could benefit late-life brain health

byUniversity College LondonDeletion of A2B receptors in hippocampal astrocytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07611-wA key mechanism which detects when the brain needs

Updated on:July 05,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on: March 02,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on:March 02,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on: March 13,2024

Oxytocin: The love hormone that holds the key to better memory

byTokyo University of ScienceResearchers discovered that activating a specific group of oxytocin neurons in the mouse brain improves performance in novel object recognition tasks. Credit: Akiyos

Updated on:March 13,2024

Genetic 'whiteout' offers hope to children living with dementia

by Murdoch UniversityChildren living with dementia have the same symptoms as adults with dementia, in that they are losing memories and face a gradual decline in health, with most not reaching ad

Updated on: June 14,2024

Genetic 'whiteout' offers hope to children living with dementia

by Murdoch UniversityChildren living with dementia have the same symptoms as adults with dementia, in that they are losing memories and face a gradual decline in health, with most not reaching ad

Updated on:June 14,2024