New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on: March 02,2024

New Alzheimer's disease pathways identified

by University of LübeckPath model of main findings. This path model summarizes the main-effect mediation model. Circles indicate principal components or latent variables, rectangles represent observed

Updated on:March 02,2024

Alzheimer-linked protein complex at super resolution

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainWith the advent of super-resolution microscopy, scientists can study close protein associations better than ever before.

Updated on: May 05,2024

Alzheimer-linked protein complex at super resolution

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainWith the advent of super-resolution microscopy, scientists can study close protein associations better than ever before.

Updated on:May 05,2024

Newly discovered mechanism in mitochondria could lead to new treatment for muscle disorders

byUniversity of CopenhagenCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-54183-4Researchers have discovered a mechanism in our cells that is essential to energy producti

Updated on: December 23,2024

Newly discovered mechanism in mitochondria could lead to new treatment for muscle disorders

byUniversity of CopenhagenCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-54183-4Researchers have discovered a mechanism in our cells that is essential to energy producti

Updated on:December 23,2024

Care more expensive for dementia patients and families in last years of life

by The Mount Sinai HospitalThe cost of care over the last five years of life for patients with dementia is significantly higher than for patients who die from heart disease, cancer, or other caus

Updated on: February 26,2024

Care more expensive for dementia patients and families in last years of life

by The Mount Sinai HospitalThe cost of care over the last five years of life for patients with dementia is significantly higher than for patients who die from heart disease, cancer, or other caus

Updated on:February 26,2024

Researchers propose a new way to identify when consciousness emerges in human infancy

byUniversity of BirminghamCredit: Unsplash/CC0 Public DomainAcademics are proposing a new and improved way to help researchers discover when consciousness emerges in human infancy.When over the

Updated on: March 28,2024

Researchers propose a new way to identify when consciousness emerges in human infancy

byUniversity of BirminghamCredit: Unsplash/CC0 Public DomainAcademics are proposing a new and improved way to help researchers discover when consciousness emerges in human infancy.When over the

Updated on:March 28,2024

Brain modeling identifies circuits implicated in consciousness

by Human Brain ProjectResponse differences in brain circuits when broadcasting (top row) or receiving signals (bottom row). Left: healthy controls; Middle: unresponsive wakefulness; Right: minimally c

Updated on: February 21,2024

Brain modeling identifies circuits implicated in consciousness

by Human Brain ProjectResponse differences in brain circuits when broadcasting (top row) or receiving signals (bottom row). Left: healthy controls; Middle: unresponsive wakefulness; Right: minimally c

Updated on:February 21,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on: March 28,2024

A new approach to treating amyotrophic lateral sclerosis and frontotemporal dementia

by Academia SinicaSchematic representation of mechanisms involved in poly-GR/-PR-induced neuronal degradation and the potential therapeutic action of the sulfated disaccharide SOS. Credit: Academia Si

Updated on:March 28,2024

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on: January 15,2025

Discovery of cilia defects in ALS patients suggests new treatment path

byVIB (the Flanders Institute for Biotechnology)Motor neurons with damaged primary cilia (green) from patients with the C21orf2 mutation. Credit: VIBAmyotrophic lateral sclerosis (ALS) is a deva

Updated on:January 15,2025

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on: January 12,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on:January 12,2024

Silent synapses are abundant in the adult brain

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT neuroscientists have discovered that the adult brain contains millions of "silent synapses"—im

Updated on: February 05,2024

Silent synapses are abundant in the adult brain

by Anne Trafton,Massachusetts Institute of TechnologyCredit: Pixabay/CC0 Public DomainMIT neuroscientists have discovered that the adult brain contains millions of "silent synapses"—im

Updated on:February 05,2024

Symptom persistence during first year following traumatic brain injury

by Mary Ann Liebert, IncNumber of symptoms endorsed at any severity by traumatic brain injury (TBI) severity subgroup and time. mTBI, mild TBI (admission Glasgow Coma Scale score 13–15); msTBI, m

Updated on: February 03,2024

Symptom persistence during first year following traumatic brain injury

by Mary Ann Liebert, IncNumber of symptoms endorsed at any severity by traumatic brain injury (TBI) severity subgroup and time. mTBI, mild TBI (admission Glasgow Coma Scale score 13–15); msTBI, m

Updated on:February 03,2024