New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

People with dementia could be missing out on post-diagnosis care

by Newcastle UniversityCredit: Unsplash/CC0 Public DomainA new report has found that as many as 85% of people with dementia could be missing out on important post-diagnosis care.Now world-leading

Updated on: May 09,2024

People with dementia could be missing out on post-diagnosis care

by Newcastle UniversityCredit: Unsplash/CC0 Public DomainA new report has found that as many as 85% of people with dementia could be missing out on important post-diagnosis care.Now world-leading

Updated on:May 09,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on: January 12,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on:January 12,2024

How gut neurons communicate with the brain to control thirst

by Lori Dajose,California Institute of TechnologyFig. 1: The vagus nerve responds to visceral osmolality changes. Credit: DOI: 10.1038/s41586-021-04359-5Drinking a glass of water is often suffic

Updated on: February 05,2024

How gut neurons communicate with the brain to control thirst

by Lori Dajose,California Institute of TechnologyFig. 1: The vagus nerve responds to visceral osmolality changes. Credit: DOI: 10.1038/s41586-021-04359-5Drinking a glass of water is often suffic

Updated on:February 05,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on: March 19,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on:March 19,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on: June 14,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on:June 14,2024

Women's blood lipid metabolism found to be better at countering effects of sleep apnea

by University of OttawaSubjects were seated for six hours with an intravenous catheter to measure blood lipids, breathing medical nitrogen to simulate sleep apnea. Credit: University of OttawaSle

Updated on: March 05,2024

Women's blood lipid metabolism found to be better at countering effects of sleep apnea

by University of OttawaSubjects were seated for six hours with an intravenous catheter to measure blood lipids, breathing medical nitrogen to simulate sleep apnea. Credit: University of OttawaSle

Updated on:March 05,2024

New strategy for assessing natural history of leukodystrophies

by Children's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainNatural history studies serve as an important standard in medical research because they analyze demographic, genetic, enviro

Updated on: May 14,2024

New strategy for assessing natural history of leukodystrophies

by Children's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainNatural history studies serve as an important standard in medical research because they analyze demographic, genetic, enviro

Updated on:May 14,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Researchers study connection between cholesterol level and cognitive decline in old age

by Heidelberg UniversityChanges in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University'

Updated on: February 26,2024

Researchers study connection between cholesterol level and cognitive decline in old age

by Heidelberg UniversityChanges in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University'

Updated on:February 26,2024

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on: June 18,2024

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on:June 18,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on: March 07,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on:March 07,2024