Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on: January 12,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on:January 12,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on: June 14,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on:June 14,2024

COVID-19: Advice for caring for people with Alzheimer's disease, mild cognitive impairment

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWith the COVID-19 pandemic at the forefront of daily life, how much information should you share with a loved one who has Alzheimer's disea

Updated on: March 26,2024

COVID-19: Advice for caring for people with Alzheimer's disease, mild cognitive impairment

by From Mayo Clinic News NetworkCredit: CC0 Public DomainWith the COVID-19 pandemic at the forefront of daily life, how much information should you share with a loved one who has Alzheimer's disea

Updated on:March 26,2024

People with dementia could be missing out on post-diagnosis care

by Newcastle UniversityCredit: Unsplash/CC0 Public DomainA new report has found that as many as 85% of people with dementia could be missing out on important post-diagnosis care.Now world-leading

Updated on: May 09,2024

People with dementia could be missing out on post-diagnosis care

by Newcastle UniversityCredit: Unsplash/CC0 Public DomainA new report has found that as many as 85% of people with dementia could be missing out on important post-diagnosis care.Now world-leading

Updated on:May 09,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on: July 31,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on:July 31,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on: March 30,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on:March 30,2024

Having dementia and reduction in social participation are associated with increased depression and anxiety

by IOS PressMental health and activity participation by dementia status per year of assessment. A) Proportion of depressive symptoms. B) Proportion of anxiety. C) Mean score of social activity. D

Updated on: June 07,2024

Having dementia and reduction in social participation are associated with increased depression and anxiety

by IOS PressMental health and activity participation by dementia status per year of assessment. A) Proportion of depressive symptoms. B) Proportion of anxiety. C) Mean score of social activity. D

Updated on:June 07,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on: August 08,2024

New visual technique could advance early detection of neurodegenerative diseases

byUniversity of MinnesotaIntroduction and overview of Cap-QuIC method. Credit:npj Biosensing(2024). DOI: 10.1038/s44328-024-00003-0Researchers at the University of Minnesota have dev

Updated on:August 08,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on: October 16,2024

Turning brain cells on using the power of light: Researchers refine noninvasive method of bioluminescent optogenetics

by Kelsie Smith Hayduk,University of Rochester(A) Schematic illustration of the LMO7 molecule. (B) Representative histological images showing fluorescence expression in the left SI of a mouse. (

Updated on:October 16,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

Record month for dementia diagnosis shows need for better tools, treatments

by Alzheimer's Research UKCredit: CC0 Public DomainAlzheimer's Research UK is calling for continued improvements in the way the UK diagnoses and treats dementia after a record number of p

Updated on: May 11,2024

Record month for dementia diagnosis shows need for better tools, treatments

by Alzheimer's Research UKCredit: CC0 Public DomainAlzheimer's Research UK is calling for continued improvements in the way the UK diagnoses and treats dementia after a record number of p

Updated on:May 11,2024