Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on: March 07,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on:March 07,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on: March 02,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on:March 02,2024

Researchers achieve success in allowing a patient to 'speak' using only the power of thought

byTel-Aviv UniversityAn image from the experiment of the speech neuroprosthesis (a.k.a speech brain-computer interface). It shows the participant who is completely silent, with his mouth closed,

Updated on: July 17,2024

Researchers achieve success in allowing a patient to 'speak' using only the power of thought

byTel-Aviv UniversityAn image from the experiment of the speech neuroprosthesis (a.k.a speech brain-computer interface). It shows the participant who is completely silent, with his mouth closed,

Updated on:July 17,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on: May 08,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on:May 08,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Psychotropic meds tied to risk for post-COVID dementia in seniors

Pre-COVID-19 psychotropic medication use is associated with higher risk for incident dementia following hospitalization for COVID-19 (post-COVID dementia) in older adults, according to a study publish

Updated on: July 04,2024

Psychotropic meds tied to risk for post-COVID dementia in seniors

Pre-COVID-19 psychotropic medication use is associated with higher risk for incident dementia following hospitalization for COVID-19 (post-COVID dementia) in older adults, according to a study publish

Updated on:July 04,2024

Systemic sclerosis is on the rise in Quebec, especially in children, study finds

by Claire Loewen,McGill UniversityAge-standardized incidence rates (ASIR) over time (1996–2019) for females, males, and both. The gray shading depicts the 95% confidence intervals for the annual

Updated on: July 17,2024

Systemic sclerosis is on the rise in Quebec, especially in children, study finds

by Claire Loewen,McGill UniversityAge-standardized incidence rates (ASIR) over time (1996–2019) for females, males, and both. The gray shading depicts the 95% confidence intervals for the annual

Updated on:July 17,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on: March 19,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on:March 19,2024

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on: June 18,2024

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on:June 18,2024

Dementia fighter: Orienteering helps brain and body alike, with greater benefits for those who move quickest

by McMaster UniversityA new study finds orienteering helps both brain and body, with greater benefits for those who move quickest. Credit: McMaster UniversityThe sport of orienteering, which simu

Updated on: June 15,2024

Dementia fighter: Orienteering helps brain and body alike, with greater benefits for those who move quickest

by McMaster UniversityA new study finds orienteering helps both brain and body, with greater benefits for those who move quickest. Credit: McMaster UniversityThe sport of orienteering, which simu

Updated on:June 15,2024

Models show promise in predicting cognitive decline in early Alzheimer's

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainA new study, published in the July 10 online issue ofNeurology, looks at predicting how quickly people with early Alzheimer&

Updated on: July 11,2024

Models show promise in predicting cognitive decline in early Alzheimer's

byAmerican Academy of NeurologyCredit: Pixabay/CC0 Public DomainA new study, published in the July 10 online issue ofNeurology, looks at predicting how quickly people with early Alzheimer&

Updated on:July 11,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on: March 30,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on:March 30,2024