Dementia: Blood levels could point to early loss of neuronal connections

by Marcus Neitzert,German Center for Neurodegenerative DiseasesGroup comparisons, correlation analyses, and diagnostic performance of serum beta-synuclein and plasma pTau181. (A) Serum beta-synu

Updated on: May 06,2024

Dementia: Blood levels could point to early loss of neuronal connections

by Marcus Neitzert,German Center for Neurodegenerative DiseasesGroup comparisons, correlation analyses, and diagnostic performance of serum beta-synuclein and plasma pTau181. (A) Serum beta-synu

Updated on:May 06,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on: March 02,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on:March 02,2024

Neuroscientist uses AI to map learning, decision-making, to discover how brains work

by Stacey DeLoye,University of FloridaMeta-learning of RL. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01485-3With trial and error, repetition and praise, when a puppy

Updated on: March 13,2024

Neuroscientist uses AI to map learning, decision-making, to discover how brains work

by Stacey DeLoye,University of FloridaMeta-learning of RL. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01485-3With trial and error, repetition and praise, when a puppy

Updated on:March 13,2024

How gut neurons communicate with the brain to control thirst

by Lori Dajose,California Institute of TechnologyFig. 1: The vagus nerve responds to visceral osmolality changes. Credit: DOI: 10.1038/s41586-021-04359-5Drinking a glass of water is often suffic

Updated on: February 05,2024

How gut neurons communicate with the brain to control thirst

by Lori Dajose,California Institute of TechnologyFig. 1: The vagus nerve responds to visceral osmolality changes. Credit: DOI: 10.1038/s41586-021-04359-5Drinking a glass of water is often suffic

Updated on:February 05,2024

Blood oxygen levels could explain why memory loss is an early symptom of Alzheimer's

by University of SussexCredit: Fakurian DesignIn a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for w

Updated on: March 09,2024

Blood oxygen levels could explain why memory loss is an early symptom of Alzheimer's

by University of SussexCredit: Fakurian DesignIn a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for w

Updated on:March 09,2024

Study reveals how obesity could accelerate aging in the brain

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainA new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood

Updated on: April 28,2024

Study reveals how obesity could accelerate aging in the brain

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainA new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood

Updated on:April 28,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024

Having dementia and reduction in social participation are associated with increased depression and anxiety

by IOS PressMental health and activity participation by dementia status per year of assessment. A) Proportion of depressive symptoms. B) Proportion of anxiety. C) Mean score of social activity. D

Updated on: June 07,2024

Having dementia and reduction in social participation are associated with increased depression and anxiety

by IOS PressMental health and activity participation by dementia status per year of assessment. A) Proportion of depressive symptoms. B) Proportion of anxiety. C) Mean score of social activity. D

Updated on:June 07,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on: December 11,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on:December 11,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on: May 08,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on:May 08,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on: June 18,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on:June 18,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on: March 07,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on:March 07,2024