Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on: January 12,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on:January 12,2024

Blood oxygen levels could explain why memory loss is an early symptom of Alzheimer's

by University of SussexCredit: Fakurian DesignIn a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for w

Updated on: March 09,2024

Blood oxygen levels could explain why memory loss is an early symptom of Alzheimer's

by University of SussexCredit: Fakurian DesignIn a world first, scientists from the University of Sussex have recorded blood oxygen levels in the hippocampus and provided experimental proof for w

Updated on:March 09,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on: June 18,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on:June 18,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on: May 11,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on:May 11,2024

Sound stimulation aids saccular dysfunction with Meniere disease

by Lori Solomon and Marianne Madeiros sSound stimulation of 75 dB at a frequency of 100 Hz leads to improvement in cervical vestibular-evoked myogenic potential (cVEMP) amplitude in patients with defi

Updated on: July 05,2024

Sound stimulation aids saccular dysfunction with Meniere disease

by Lori Solomon and Marianne Madeiros sSound stimulation of 75 dB at a frequency of 100 Hz leads to improvement in cervical vestibular-evoked myogenic potential (cVEMP) amplitude in patients with defi

Updated on:July 05,2024

Having dementia and reduction in social participation are associated with increased depression and anxiety

by IOS PressMental health and activity participation by dementia status per year of assessment. A) Proportion of depressive symptoms. B) Proportion of anxiety. C) Mean score of social activity. D

Updated on: June 07,2024

Having dementia and reduction in social participation are associated with increased depression and anxiety

by IOS PressMental health and activity participation by dementia status per year of assessment. A) Proportion of depressive symptoms. B) Proportion of anxiety. C) Mean score of social activity. D

Updated on:June 07,2024

Forty percent of dementia cases could be prevented or delayed by targeting 12 risk factors throughout life

by LancetCredit: CC0 Public DomainModifying 12 risk factors over the lifecourse could delay or prevent 40% of dementia cases, according to an update toThe LancetCommission on dementia

Updated on: March 13,2024

Forty percent of dementia cases could be prevented or delayed by targeting 12 risk factors throughout life

by LancetCredit: CC0 Public DomainModifying 12 risk factors over the lifecourse could delay or prevent 40% of dementia cases, according to an update toThe LancetCommission on dementia

Updated on:March 13,2024

Brain stimulation shows promise for Alzheimer's disease in early trial

by Alzheimer's Research UKPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists in the US have found that electrically stimulating regions of the brain in th

Updated on: May 13,2024

Brain stimulation shows promise for Alzheimer's disease in early trial

by Alzheimer's Research UKPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists in the US have found that electrically stimulating regions of the brain in th

Updated on:May 13,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on: May 08,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on:May 08,2024

Study reveals how obesity could accelerate aging in the brain

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainA new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood

Updated on: April 28,2024

Study reveals how obesity could accelerate aging in the brain

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainA new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood

Updated on:April 28,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on: May 18,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on:May 18,2024