Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024

Dementia: Blood levels could point to early loss of neuronal connections

by Marcus Neitzert,German Center for Neurodegenerative DiseasesGroup comparisons, correlation analyses, and diagnostic performance of serum beta-synuclein and plasma pTau181. (A) Serum beta-synu

Updated on: May 06,2024

Dementia: Blood levels could point to early loss of neuronal connections

by Marcus Neitzert,German Center for Neurodegenerative DiseasesGroup comparisons, correlation analyses, and diagnostic performance of serum beta-synuclein and plasma pTau181. (A) Serum beta-synu

Updated on:May 06,2024

Simple blood test can accurately reveal underlying neurodegeneration

by King's College LondonCredit: CC0 Public DomainA new study of over 3000 people led by King's College London in collaboration with Lund University, has shown for the first time that a si

Updated on: June 20,2024

Simple blood test can accurately reveal underlying neurodegeneration

by King's College LondonCredit: CC0 Public DomainA new study of over 3000 people led by King's College London in collaboration with Lund University, has shown for the first time that a si

Updated on:June 20,2024

Reducing dementia risks

by Deb BalzerCredit: Pixabay/CC0 Public DomainFormer first lady Rosalynn Carter has been diagnosed with dementia. A family statement, posted on The Carter Center website, says that she continues to li

Updated on: April 01,2024

Reducing dementia risks

by Deb BalzerCredit: Pixabay/CC0 Public DomainFormer first lady Rosalynn Carter has been diagnosed with dementia. A family statement, posted on The Carter Center website, says that she continues to li

Updated on:April 01,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on: January 12,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on:January 12,2024

AAIC: Turnover kinetics vary for different amyloid beta isoforms

(HealthDay)—Amyloid beta (Aβ)38 has faster turnover kinetics than Aβ40 and Aβ42, according to a study published online July 19 inAlzheimer's & Dementiato coincide with presentation

Updated on: March 19,2024

AAIC: Turnover kinetics vary for different amyloid beta isoforms

(HealthDay)—Amyloid beta (Aβ)38 has faster turnover kinetics than Aβ40 and Aβ42, according to a study published online July 19 inAlzheimer's & Dementiato coincide with presentation

Updated on:March 19,2024

A million Aussies will have dementia by 2056, so now is the time to act on prevention

by Cate Swannell, Medical Journal of AustraliaCredit: CC0 Public DomainDementia prevention needs to be Australia's next public health area of focus, as the nation heads towards a projected number

Updated on: May 20,2024

A million Aussies will have dementia by 2056, so now is the time to act on prevention

by Cate Swannell, Medical Journal of AustraliaCredit: CC0 Public DomainDementia prevention needs to be Australia's next public health area of focus, as the nation heads towards a projected number

Updated on:May 20,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on: December 11,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on:December 11,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on: May 18,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on:May 18,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

Is that 'midlife crisis' really Alzheimer's disease?

by Carmela Tartaglia,The ConversationCredit: AI-generated imageImagine you tell your 55 year-old mom you're going to get married and she's too disorganized to help you with the wedding p

Updated on: March 13,2024

Is that 'midlife crisis' really Alzheimer's disease?

by Carmela Tartaglia,The ConversationCredit: AI-generated imageImagine you tell your 55 year-old mom you're going to get married and she's too disorganized to help you with the wedding p

Updated on:March 13,2024

Neuroscientist uses AI to map learning, decision-making, to discover how brains work

by Stacey DeLoye,University of FloridaMeta-learning of RL. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01485-3With trial and error, repetition and praise, when a puppy

Updated on: March 13,2024

Neuroscientist uses AI to map learning, decision-making, to discover how brains work

by Stacey DeLoye,University of FloridaMeta-learning of RL. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01485-3With trial and error, repetition and praise, when a puppy

Updated on:March 13,2024