Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on: May 11,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on:May 11,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Systemic sclerosis is on the rise in Quebec, especially in children, study finds

by Claire Loewen,McGill UniversityAge-standardized incidence rates (ASIR) over time (1996–2019) for females, males, and both. The gray shading depicts the 95% confidence intervals for the annual

Updated on: July 17,2024

Systemic sclerosis is on the rise in Quebec, especially in children, study finds

by Claire Loewen,McGill UniversityAge-standardized incidence rates (ASIR) over time (1996–2019) for females, males, and both. The gray shading depicts the 95% confidence intervals for the annual

Updated on:July 17,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on: March 19,2024

Poor neighborhoods linked to elevated dementia risk and faster brain aging

by Duke UniversityCredit: CC0 Public DomainLiving in a poorer neighborhood is linked to accelerated brain aging and increased dementia risk early in life, regardless of income level or education,

Updated on:March 19,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on: June 18,2024

Computer simulations explore how Alzheimer's disease starts

by Rice UniversityA team of Rice University researchers built computer simulations of amyloid beta proteins to see what their energy landscapes reveal about the formation of plaques in patients w

Updated on:June 18,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024

Loneliness associated with increased risk of dementia in older adults

by NYU Langone HealthChart showing incident of dementia for adults under age 80 without APOE ε4 allele, a genetic risk factor for Alzheimer's disease. Credit: NYU Langone HealthAs social isol

Updated on: June 05,2024

Loneliness associated with increased risk of dementia in older adults

by NYU Langone HealthChart showing incident of dementia for adults under age 80 without APOE ε4 allele, a genetic risk factor for Alzheimer's disease. Credit: NYU Langone HealthAs social isol

Updated on:June 05,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on: June 14,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on:June 14,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on: December 11,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on:December 11,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on: April 02,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on:April 02,2024

Sound stimulation aids saccular dysfunction with Meniere disease

by Lori Solomon and Marianne Madeiros sSound stimulation of 75 dB at a frequency of 100 Hz leads to improvement in cervical vestibular-evoked myogenic potential (cVEMP) amplitude in patients with defi

Updated on: July 05,2024

Sound stimulation aids saccular dysfunction with Meniere disease

by Lori Solomon and Marianne Madeiros sSound stimulation of 75 dB at a frequency of 100 Hz leads to improvement in cervical vestibular-evoked myogenic potential (cVEMP) amplitude in patients with defi

Updated on:July 05,2024