Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on: July 31,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on:July 31,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on: March 02,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on:March 02,2024

Genetic 'whiteout' offers hope to children living with dementia

by Murdoch UniversityChildren living with dementia have the same symptoms as adults with dementia, in that they are losing memories and face a gradual decline in health, with most not reaching ad

Updated on: June 14,2024

Genetic 'whiteout' offers hope to children living with dementia

by Murdoch UniversityChildren living with dementia have the same symptoms as adults with dementia, in that they are losing memories and face a gradual decline in health, with most not reaching ad

Updated on:June 14,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on: December 11,2024

Understanding the genetic roots of rare mutations in Alzheimer's disease

byVIB (the Flanders Institute for Biotechnology)Hippocampal neurons with staining for endosomes (turquoise and purple) and lysosomes (yellow). When the PSEN2 gene is absent or carries a familial

Updated on:December 11,2024

Signals from muscle protect from dementia

by St. Jude Children's Research HospitalResearch in the lab of Fabio Demontis, PhD, of Developmental Neurobiology, used immunostaining and confocal microscopy on fruit fly brain and retina ce

Updated on: June 14,2024

Signals from muscle protect from dementia

by St. Jude Children's Research HospitalResearch in the lab of Fabio Demontis, PhD, of Developmental Neurobiology, used immunostaining and confocal microscopy on fruit fly brain and retina ce

Updated on:June 14,2024

Improved fitness can mean living longer without dementia

by Norwegian University of Science and TechnologyCredit: AI-generated imageStaying fit or improving fitness over time should be a goal for anyone who wants to reduce the likelihood of getting dem

Updated on: June 24,2024

Improved fitness can mean living longer without dementia

by Norwegian University of Science and TechnologyCredit: AI-generated imageStaying fit or improving fitness over time should be a goal for anyone who wants to reduce the likelihood of getting dem

Updated on:June 24,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on: May 08,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on:May 08,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on: May 11,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on:May 11,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on: April 02,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on:April 02,2024

Study reveals how obesity could accelerate aging in the brain

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainA new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood

Updated on: April 28,2024

Study reveals how obesity could accelerate aging in the brain

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainA new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood

Updated on:April 28,2024