AAIC: Turnover kinetics vary for different amyloid beta isoforms

(HealthDay)—Amyloid beta (Aβ)38 has faster turnover kinetics than Aβ40 and Aβ42, according to a study published online July 19 inAlzheimer's & Dementiato coincide with presentation

Updated on: March 19,2024

AAIC: Turnover kinetics vary for different amyloid beta isoforms

(HealthDay)—Amyloid beta (Aβ)38 has faster turnover kinetics than Aβ40 and Aβ42, according to a study published online July 19 inAlzheimer's & Dementiato coincide with presentation

Updated on:March 19,2024

Parkinson's disease gene variant found in some people of African ancestry

by National Institutes of HealthScientists discovered a gene variant, found almost exclusively in the genomes of individuals of African ancestry, that increases the risk of having Parkinson's

Updated on: June 23,2024

Parkinson's disease gene variant found in some people of African ancestry

by National Institutes of HealthScientists discovered a gene variant, found almost exclusively in the genomes of individuals of African ancestry, that increases the risk of having Parkinson's

Updated on:June 23,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on: June 14,2024

Genes, cardiovascular health each factor into dementia risk

by University of Texas Health Science Center at San AntonioCredit: CC0 Public DomainGenes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. res

Updated on:June 14,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on: May 11,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on:May 11,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on: April 28,2024

New insights into the molecular mechanisms behind the action of secretagogin

byKarolinska InstitutetThe vesicular release of neurotransmitters and hormones relies on the SNARE-complex formed by three proteins: VAMP (blue), Syntaxin (pink) and SNAP-25 (green). Secretagoin

Updated on:April 28,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on: May 18,2024

Energy storehouses in the brain may be source of Alzheimer's, targets of new therapy

by Arizona State UniversityDiego Mastroeni is a researcher in the ASU-Banner Neurodegenerative Disease Research Center. Credit: Biodesign Institute at Arizona State UniversityAlzheimer's dise

Updated on:May 18,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on: January 12,2024

New molecule to fight against transthyretin amyloidosis

byAutonomous University of BarcelonaCredit:Journal of Medicinal Chemistry(2022). DOI: 10.1021/acs.jmedchem.2c01195Researchers from IBB-UAB have developed a second-generation molecule

Updated on:January 12,2024

Hit the sleep 'sweet spot' to keep brain sharp

by Washington University School of MedicineCredit: CC0 Public DomainLike so many other good things in life, sleep is best in moderation. A multiyear study of older adults found that both short an

Updated on: May 13,2024

Hit the sleep 'sweet spot' to keep brain sharp

by Washington University School of MedicineCredit: CC0 Public DomainLike so many other good things in life, sleep is best in moderation. A multiyear study of older adults found that both short an

Updated on:May 13,2024

How does the brain know whether our actions actually make a difference?

by Champalimaud Centre for the UnknownIn "controllable houses", the door's color determines which room it leads to. In contrast, in "uncontrollable houses" the sequence of room

Updated on: February 21,2024

How does the brain know whether our actions actually make a difference?

by Champalimaud Centre for the UnknownIn "controllable houses", the door's color determines which room it leads to. In contrast, in "uncontrollable houses" the sequence of room

Updated on:February 21,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on: May 08,2024

New artificial neural network detects radiographic sacroiliitis with accuracy

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that an

Updated on:May 08,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on: October 09,2024

Study reveals key role of TRIO gene in epileptic encephalopathies

byUniversity of MontrealDefective migration of MGE-derived cortical INs inTrio–/–embryos. Credit:Molecular Psychiatry(2024). DOI: 10.1038/s41380-024-02742-yWhat are the m

Updated on:October 09,2024

'Super-agers' study may reveal secrets to staying young

Mary Helen Abbott, 77, paints her lips bright pink, still smokes the occasional cigarette, keeps up on all the gossip at the retirement home and wears a short skirt to fitness class.She giggles as the

Updated on: February 26,2024

'Super-agers' study may reveal secrets to staying young

Mary Helen Abbott, 77, paints her lips bright pink, still smokes the occasional cigarette, keeps up on all the gossip at the retirement home and wears a short skirt to fitness class.She giggles as the

Updated on:February 26,2024