Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Dementia: Blood levels could point to early loss of neuronal connections

by Marcus Neitzert,German Center for Neurodegenerative DiseasesGroup comparisons, correlation analyses, and diagnostic performance of serum beta-synuclein and plasma pTau181. (A) Serum beta-synu

Updated on: May 06,2024

Dementia: Blood levels could point to early loss of neuronal connections

by Marcus Neitzert,German Center for Neurodegenerative DiseasesGroup comparisons, correlation analyses, and diagnostic performance of serum beta-synuclein and plasma pTau181. (A) Serum beta-synu

Updated on:May 06,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on: March 02,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on:March 02,2024

Loneliness associated with increased risk of dementia in older adults

by NYU Langone HealthChart showing incident of dementia for adults under age 80 without APOE ε4 allele, a genetic risk factor for Alzheimer's disease. Credit: NYU Langone HealthAs social isol

Updated on: June 05,2024

Loneliness associated with increased risk of dementia in older adults

by NYU Langone HealthChart showing incident of dementia for adults under age 80 without APOE ε4 allele, a genetic risk factor for Alzheimer's disease. Credit: NYU Langone HealthAs social isol

Updated on:June 05,2024

Brain stimulation shows promise for Alzheimer's disease in early trial

by Alzheimer's Research UKPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists in the US have found that electrically stimulating regions of the brain in th

Updated on: May 13,2024

Brain stimulation shows promise for Alzheimer's disease in early trial

by Alzheimer's Research UKPET scan of a human brain with Alzheimer's disease. Credit: public domainScientists in the US have found that electrically stimulating regions of the brain in th

Updated on:May 13,2024

Injuries to primary visual cortex cause long-term dysfunction of neural circuits

by Marcin Powęska,Polish Academy of SciencesInjuries to primary visual cortex cause long-term dysfunction of neural circuits. Credit: ICTER / Grzegorz KrzyzewskiEven mild head injuries can mean

Updated on: February 05,2024

Injuries to primary visual cortex cause long-term dysfunction of neural circuits

by Marcin Powęska,Polish Academy of SciencesInjuries to primary visual cortex cause long-term dysfunction of neural circuits. Credit: ICTER / Grzegorz KrzyzewskiEven mild head injuries can mean

Updated on:February 05,2024

Study suggests that attention networks support changes in cortical organization and cognition during childhood

by Ingrid Fadelli , Medical XpressVentral attention network areas demonstrate high population-level degree centrality but pronounced functional changes across development. Credit:Nature Neurosci

Updated on: September 23,2024

Study suggests that attention networks support changes in cortical organization and cognition during childhood

by Ingrid Fadelli , Medical XpressVentral attention network areas demonstrate high population-level degree centrality but pronounced functional changes across development. Credit:Nature Neurosci

Updated on:September 23,2024

Improved fitness can mean living longer without dementia

by Norwegian University of Science and TechnologyCredit: AI-generated imageStaying fit or improving fitness over time should be a goal for anyone who wants to reduce the likelihood of getting dem

Updated on: June 24,2024

Improved fitness can mean living longer without dementia

by Norwegian University of Science and TechnologyCredit: AI-generated imageStaying fit or improving fitness over time should be a goal for anyone who wants to reduce the likelihood of getting dem

Updated on:June 24,2024

Study reveals how obesity could accelerate aging in the brain

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainA new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood

Updated on: April 28,2024

Study reveals how obesity could accelerate aging in the brain

byAmerican Physiological SocietyCredit: Pixabay/CC0 Public DomainA new study conducted in mice traces how obesity and a high-fat diet may accelerate aging in the blood vessels that supply blood

Updated on:April 28,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024

People with dementia could be missing out on post-diagnosis care

by Newcastle UniversityCredit: Unsplash/CC0 Public DomainA new report has found that as many as 85% of people with dementia could be missing out on important post-diagnosis care.Now world-leading

Updated on: May 09,2024

People with dementia could be missing out on post-diagnosis care

by Newcastle UniversityCredit: Unsplash/CC0 Public DomainA new report has found that as many as 85% of people with dementia could be missing out on important post-diagnosis care.Now world-leading

Updated on:May 09,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024