Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on: July 01,2024 4

Untangling APOE ε4's association to tau tangles

by McGill UniversityCredit: CC0 Public DomainFor years, physicians have been aware that patients carrying the apolipoprotein E4 (APOEε4) gene are at a greater risk of developing Alzheimer's d

Updated on:July 01,2024 4

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on: July 31,2024 0

Lab-grown human neuron assembloids effectively model synaptic plasticity

bySt. Jude Children's Research HospitalCredit:Cell Reports(2024). DOI: 10.1016/j.celrep.2024.114503The ability to study human neurological systems depends on having viable, accur

Updated on:July 31,2024 0

Simple test could help predict risk of Alzheimer's disease 20 years in advance

by The Australian National Universitya) Sketch of protein translocation through a SiNx nanopore membrane. The proteins in a buffered electrolyte solution are placed in the cis and trans channels

Updated on: March 02,2024 12

Simple test could help predict risk of Alzheimer's disease 20 years in advance

by The Australian National Universitya) Sketch of protein translocation through a SiNx nanopore membrane. The proteins in a buffered electrolyte solution are placed in the cis and trans channels

Updated on:March 02,2024 12

From Alzheimer's to autism, nuclear neurology could launch revolution in diagnosing and treating brain diseases

by Ellen Goldbaum,University at BuffaloImage of glucose metabolism PET overlaid on CT in an Alzheimer's patient with mild dementia. Green arrow points to regional hypometabolism in the media

Updated on: May 13,2024 5

From Alzheimer's to autism, nuclear neurology could launch revolution in diagnosing and treating brain diseases

by Ellen Goldbaum,University at BuffaloImage of glucose metabolism PET overlaid on CT in an Alzheimer's patient with mild dementia. Green arrow points to regional hypometabolism in the media

Updated on:May 13,2024 5

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on: February 26,2024 11

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on:February 26,2024 11

Form of B12 deficiency in cerebral spinal fluid found to negatively affect the central nervous system

by Bob Yirka , Medical XpressA patient with an unsual MRI and neurologic deficits eluded typical diagnostic tests.Credit: John PluvinageA large team of doctors and medical researchers with diver

Updated on: July 05,2024 0

Form of B12 deficiency in cerebral spinal fluid found to negatively affect the central nervous system

by Bob Yirka , Medical XpressA patient with an unsual MRI and neurologic deficits eluded typical diagnostic tests.Credit: John PluvinageA large team of doctors and medical researchers with diver

Updated on:July 05,2024 0

Caregiver burden in dementia during the COVID-19 crisis

by IOS PressCredit: CC0 Public DomainCaregivers of people with dementia and milder forms of neurocognitive disorder bear a heavy burden. They are constantly confronted with challenging symptoms a

Updated on: March 30,2024 16

Caregiver burden in dementia during the COVID-19 crisis

by IOS PressCredit: CC0 Public DomainCaregivers of people with dementia and milder forms of neurocognitive disorder bear a heavy burden. They are constantly confronted with challenging symptoms a

Updated on:March 30,2024 16

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on: July 31,2024 0

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on:July 31,2024 0

Using herpes drugs to slow down Alzheimer's disease could become reality

by Umea UniversityThe first clinical study to investigate if herpes virus drugs can have an effect on fundamental Alzheimer's disease processes has been launched at Umeå University in Sweden.

Updated on: March 07,2024 10

Using herpes drugs to slow down Alzheimer's disease could become reality

by Umea UniversityThe first clinical study to investigate if herpes virus drugs can have an effect on fundamental Alzheimer's disease processes has been launched at Umeå University in Sweden.

Updated on:March 07,2024 10

Study finds cerebrovascular disease to be major determinant of psychosis in patients with Alzheimer's

by St. Michael's HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.About half of all patients with Alzheimer's disease develop symptom

Updated on: February 27,2024 15

Study finds cerebrovascular disease to be major determinant of psychosis in patients with Alzheimer's

by St. Michael's HospitalDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.About half of all patients with Alzheimer's disease develop symptom

Updated on:February 27,2024 15

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on: March 13,2024 11

A common marker of neurological diseases may play a role in healthy brains

byNational Institutes of HealthLocalization of α-syn Ser129P and effects of phosphorylation on synaptic targeting. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.11.020Researchers h

Updated on:March 13,2024 11

Alzheimer's disease and type 2 diabetes: Synthetic peptides may suppress formation of harmful amyloid aggregates

by Technical University MunichProposed mechanism and hypothetical models of IAPP/ACM nanofiber co-assembly versus IAPP amyloid self-assembly. The lower part, IAPP self-assembly into toxic oligome

Updated on: April 08,2024 20

Alzheimer's disease and type 2 diabetes: Synthetic peptides may suppress formation of harmful amyloid aggregates

by Technical University MunichProposed mechanism and hypothetical models of IAPP/ACM nanofiber co-assembly versus IAPP amyloid self-assembly. The lower part, IAPP self-assembly into toxic oligome

Updated on:April 08,2024 20