Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Is that 'midlife crisis' really Alzheimer's disease?

by Carmela Tartaglia,The ConversationCredit: AI-generated imageImagine you tell your 55 year-old mom you're going to get married and she's too disorganized to help you with the wedding p

Updated on: March 13,2024

Is that 'midlife crisis' really Alzheimer's disease?

by Carmela Tartaglia,The ConversationCredit: AI-generated imageImagine you tell your 55 year-old mom you're going to get married and she's too disorganized to help you with the wedding p

Updated on:March 13,2024

Neuroscientist uses AI to map learning, decision-making, to discover how brains work

by Stacey DeLoye,University of FloridaMeta-learning of RL. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01485-3With trial and error, repetition and praise, when a puppy

Updated on: March 13,2024

Neuroscientist uses AI to map learning, decision-making, to discover how brains work

by Stacey DeLoye,University of FloridaMeta-learning of RL. Credit:Nature Neuroscience(2023). DOI: 10.1038/s41593-023-01485-3With trial and error, repetition and praise, when a puppy

Updated on:March 13,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on: March 02,2024

'Anti-tangle' molecule could aid search for new dementia treatments, say scientists

by Vicky Just,University of BathThe solution NMR structure of αS1–25(A) The average structure of αS1–25derived from the 20 lowest-energy structures. Charged (blue: positive, red: negative)

Updated on:March 02,2024

Protein droplets likely don't cause Parkinson's, study suggests

byPaul Scherrer InstituteCredit:Advanced Science(2024). DOI: 10.1002/advs.202308279Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological h

Updated on: July 17,2024

Protein droplets likely don't cause Parkinson's, study suggests

byPaul Scherrer InstituteCredit:Advanced Science(2024). DOI: 10.1002/advs.202308279Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological h

Updated on:July 17,2024

From 'demented' to 'person with dementia': how and why the language of disability changed

by Roland Sussex,The ConversationThe initial aim of political correctness, to establish non-hateful language was, and still is, admirable. Credit: Nathan Anderson/UnsplashIn the second half of t

Updated on: May 13,2024

From 'demented' to 'person with dementia': how and why the language of disability changed

by Roland Sussex,The ConversationThe initial aim of political correctness, to establish non-hateful language was, and still is, admirable. Credit: Nathan Anderson/UnsplashIn the second half of t

Updated on:May 13,2024

New blood test for detecting Alzheimer's disease

by Lund UniversityCredit: CC0 Public DomainResearchers from Lund University, together with the Roche pharmaceutical company, have developed a method to create a new blood marker capable of detect

Updated on: June 20,2024

New blood test for detecting Alzheimer's disease

by Lund UniversityCredit: CC0 Public DomainResearchers from Lund University, together with the Roche pharmaceutical company, have developed a method to create a new blood marker capable of detect

Updated on:June 20,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on: August 01,2024

Llama nanobodies: New therapy can neutralize a wide variety of HIV-1 strains

by Noelle Toumey Reetz,Georgia State UniversityCryo-EM structures of nanobodies R27 and G36 in complex with HIV-1 Env trimer reveal modes of recognition similar to J3. Credit:Advanced Scie

Updated on:August 01,2024

Optical sensors and lab-on-fiber technology may detect Alzheimer's disease at early stages

by Wileya) 3D view of the nanofunctionalized D-shaped lab-on-fiber sensor. b) Related sensing mechanism based on the evaluation of refractive index changes, through evanescent wave interaction, t

Updated on: June 05,2024

Optical sensors and lab-on-fiber technology may detect Alzheimer's disease at early stages

by Wileya) 3D view of the nanofunctionalized D-shaped lab-on-fiber sensor. b) Related sensing mechanism based on the evaluation of refractive index changes, through evanescent wave interaction, t

Updated on:June 05,2024

Study shows activity of claustrum neurons controls alertness level, engagement of sensory information

byHebrew University of JerusalemApproach for hM3Dq DREADD experiments (left) and setup (right). Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48829-6A new study has unc

Updated on: July 08,2024

Study shows activity of claustrum neurons controls alertness level, engagement of sensory information

byHebrew University of JerusalemApproach for hM3Dq DREADD experiments (left) and setup (right). Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-48829-6A new study has unc

Updated on:July 08,2024

Most Medicare beneficiaries say they don't receive cognitive assessments

by Orli Belman,University of Southern CaliforniaCredit: CC0 Public DomainNew research from the University of Southern California measured the use of Medicaid's annual wellness visits and the

Updated on: May 13,2024

Most Medicare beneficiaries say they don't receive cognitive assessments

by Orli Belman,University of Southern CaliforniaCredit: CC0 Public DomainNew research from the University of Southern California measured the use of Medicaid's annual wellness visits and the

Updated on:May 13,2024

Unraveling the neural circuit behind reduced food intake in high temperatures

byKarolinska InstitutetAcute heat reduces food intake and selectively activates α-tanycytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07232-3In a study recentlypublished&nb

Updated on: April 28,2024

Unraveling the neural circuit behind reduced food intake in high temperatures

byKarolinska InstitutetAcute heat reduces food intake and selectively activates α-tanycytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07232-3In a study recentlypublished&nb

Updated on:April 28,2024