Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on: April 16,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on:April 16,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on: March 30,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on:March 30,2024

Forty percent of dementia cases could be prevented or delayed by targeting 12 risk factors throughout life

by LancetCredit: CC0 Public DomainModifying 12 risk factors over the lifecourse could delay or prevent 40% of dementia cases, according to an update toThe LancetCommission on dementia

Updated on: March 13,2024

Forty percent of dementia cases could be prevented or delayed by targeting 12 risk factors throughout life

by LancetCredit: CC0 Public DomainModifying 12 risk factors over the lifecourse could delay or prevent 40% of dementia cases, according to an update toThe LancetCommission on dementia

Updated on:March 13,2024

New tool provides researchers with improved understanding of stem cell aging in the brain

by University of Wisconsin-MadisonPatterns in the tiny amounts of light emitted by these neural stem cells helped researchers determine whether they were active or dormant without destructive tes

Updated on: March 30,2024

New tool provides researchers with improved understanding of stem cell aging in the brain

by University of Wisconsin-MadisonPatterns in the tiny amounts of light emitted by these neural stem cells helped researchers determine whether they were active or dormant without destructive tes

Updated on:March 30,2024

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on: September 21,2024

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on:September 21,2024

MS changes the microbiome subtly but similarly, whether in US or Asia

by Kim Krieger,University of ConnecticutDisruption of Bacteroides-Prevotella correlative network in MS. a, b Correlations shared between MS and controls. c Correlations that are unique in contro

Updated on: August 08,2024

MS changes the microbiome subtly but similarly, whether in US or Asia

by Kim Krieger,University of ConnecticutDisruption of Bacteroides-Prevotella correlative network in MS. a, b Correlations shared between MS and controls. c Correlations that are unique in contro

Updated on:August 08,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on: April 06,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on:April 06,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on: November 22,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on:November 22,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Scientists isolate genes that delay Alzheimer's

by Australian National UniversityAssociate Professor Arcos-Burgos (centre) with Dr Claudio Mastronardi and Dr Hardip Patel. Credit: Stuart Hay, ANUScientists have identified a network of nine gen

Updated on: February 27,2024

Scientists isolate genes that delay Alzheimer's

by Australian National UniversityAssociate Professor Arcos-Burgos (centre) with Dr Claudio Mastronardi and Dr Hardip Patel. Credit: Stuart Hay, ANUScientists have identified a network of nine gen

Updated on:February 27,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on: April 07,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on:April 07,2024