Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on: March 07,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on:March 07,2024

Insulin resistance may lead to faster cognitive decline

by Tel Aviv UniversityCredit: Tel Aviv UniversityA new Tel Aviv University study published in theJournal of Alzheimer's Diseasefinds that insulin resistance, caused in part by obe

Updated on: March 09,2024

Insulin resistance may lead to faster cognitive decline

by Tel Aviv UniversityCredit: Tel Aviv UniversityA new Tel Aviv University study published in theJournal of Alzheimer's Diseasefinds that insulin resistance, caused in part by obe

Updated on:March 09,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on: May 18,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on:May 18,2024

Could 'love hormone' oxytocin help treat Alzheimer's disease? Here's what researchers currently know

by Eleftheria Kodosaki,The ConversationCredit: Unsplash/CC0 Public DomainOxytocin is often called "the love hormone" because of its role in social bonding, reproduction and childbirth.

Updated on: March 13,2024

Could 'love hormone' oxytocin help treat Alzheimer's disease? Here's what researchers currently know

by Eleftheria Kodosaki,The ConversationCredit: Unsplash/CC0 Public DomainOxytocin is often called "the love hormone" because of its role in social bonding, reproduction and childbirth.

Updated on:March 13,2024

Uncovering the unusual way aggregates hijack proteins

by Utrecht University,Utrecht University Faculty of ScienceTau stacking. Credit: Stefan Rudiger - Utrecht UniversityUtrecht scientists have uncovered how aggregates alter the behavior of Tau pro

Updated on: July 01,2024

Uncovering the unusual way aggregates hijack proteins

by Utrecht University,Utrecht University Faculty of ScienceTau stacking. Credit: Stefan Rudiger - Utrecht UniversityUtrecht scientists have uncovered how aggregates alter the behavior of Tau pro

Updated on:July 01,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on: November 22,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on:November 22,2024

How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on: January 12,2024

How antidepressants, ketamine and psychedelic drugs may make brains more flexible—new research

by Barbara Jacquelyn Sahakian and Christelle Langley,The ConversationCredit: Juan Gaertner/ShutterstockThe first-line pharmacological treatment for major depressive disorder (MDD) are antidepres

Updated on:January 12,2024

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on: June 14,2024

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on:June 14,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on: February 03,2024

Poor gut health may drive multiple sclerosis—better diet may ease it

by Rutgers UniversityDevelopment of colitis in spontaneous EAE mice. (A) Swollen colon in spontaneous EAE mice. (B) H&E histopathology of swollen colon isolated from spontaneous EAE and non-E

Updated on:February 03,2024

MS changes the microbiome subtly but similarly, whether in US or Asia

by Kim Krieger,University of ConnecticutDisruption of Bacteroides-Prevotella correlative network in MS. a, b Correlations shared between MS and controls. c Correlations that are unique in contro

Updated on: August 08,2024

MS changes the microbiome subtly but similarly, whether in US or Asia

by Kim Krieger,University of ConnecticutDisruption of Bacteroides-Prevotella correlative network in MS. a, b Correlations shared between MS and controls. c Correlations that are unique in contro

Updated on:August 08,2024

Scientists isolate genes that delay Alzheimer's

by Australian National UniversityAssociate Professor Arcos-Burgos (centre) with Dr Claudio Mastronardi and Dr Hardip Patel. Credit: Stuart Hay, ANUScientists have identified a network of nine gen

Updated on: February 27,2024

Scientists isolate genes that delay Alzheimer's

by Australian National UniversityAssociate Professor Arcos-Burgos (centre) with Dr Claudio Mastronardi and Dr Hardip Patel. Credit: Stuart Hay, ANUScientists have identified a network of nine gen

Updated on:February 27,2024

New tool provides researchers with improved understanding of stem cell aging in the brain

by University of Wisconsin-MadisonPatterns in the tiny amounts of light emitted by these neural stem cells helped researchers determine whether they were active or dormant without destructive tes

Updated on: March 30,2024

New tool provides researchers with improved understanding of stem cell aging in the brain

by University of Wisconsin-MadisonPatterns in the tiny amounts of light emitted by these neural stem cells helped researchers determine whether they were active or dormant without destructive tes

Updated on:March 30,2024