Opinion: New Alzheimer's drugs don't deserve the hype—here's why

by Sebastian Walsh,The ConversationCredit: AI-generated imageA prominent childhood memory is of my grandparents living with and then dying from dementia. As is universal with dementia, there was

Updated on: March 02,2024

Opinion: New Alzheimer's drugs don't deserve the hype—here's why

by Sebastian Walsh,The ConversationCredit: AI-generated imageA prominent childhood memory is of my grandparents living with and then dying from dementia. As is universal with dementia, there was

Updated on:March 02,2024

Neuronal diversity impacts the brain's information processing

by Melissa Rohman,Northwestern UniversitySpike threshold heterogeneity affects the function generation properties of spiking neural networks. (A) Reservoir computing architecture used for functi

Updated on: March 13,2024

Neuronal diversity impacts the brain's information processing

by Melissa Rohman,Northwestern UniversitySpike threshold heterogeneity affects the function generation properties of spiking neural networks. (A) Reservoir computing architecture used for functi

Updated on:March 13,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on: April 16,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on:April 16,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on: April 06,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on:April 06,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on: March 30,2024

CRISPR helps identify potential Alzheimer's-related protein

by University of TokyoCredit: CC0 Public DomainExperts at the University of Tokyo have identified a new protein in the pathway that leads to Alzheimer's disease. Researchers used the "mo

Updated on:March 30,2024

How are 'super agers' protected from Alzheimer's and mental decline?

by Alan Mozes Healthday Reporter(HealthDay)—Some older folks are still sharp as tacks and dementia-free well into their 80s and beyond. Now German researchers have uncovered a possible reason why: The

Updated on: March 13,2024

How are 'super agers' protected from Alzheimer's and mental decline?

by Alan Mozes Healthday Reporter(HealthDay)—Some older folks are still sharp as tacks and dementia-free well into their 80s and beyond. Now German researchers have uncovered a possible reason why: The

Updated on:March 13,2024

Forty percent of dementia cases could be prevented or delayed by targeting 12 risk factors throughout life

by LancetCredit: CC0 Public DomainModifying 12 risk factors over the lifecourse could delay or prevent 40% of dementia cases, according to an update toThe LancetCommission on dementia

Updated on: March 13,2024

Forty percent of dementia cases could be prevented or delayed by targeting 12 risk factors throughout life

by LancetCredit: CC0 Public DomainModifying 12 risk factors over the lifecourse could delay or prevent 40% of dementia cases, according to an update toThe LancetCommission on dementia

Updated on:March 13,2024

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on: September 21,2024

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on:September 21,2024

Drop in mortality seen with AChEI, memantine in dementia with lewy bodies

by Elana GotkineFor patients with dementia with Lewy bodies (DLB), treatment with acetylcholinesterase inhibitors (AChEIs) and/or memantine is associated with reduced hospital admissions and mortality

Updated on: June 24,2024

Drop in mortality seen with AChEI, memantine in dementia with lewy bodies

by Elana GotkineFor patients with dementia with Lewy bodies (DLB), treatment with acetylcholinesterase inhibitors (AChEIs) and/or memantine is associated with reduced hospital admissions and mortality

Updated on:June 24,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on: April 07,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on:April 07,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on: November 22,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on:November 22,2024

Examining dementia risk in adults with intellectual disability

by Okayama UniversityLittle is known about the risk factors of dementia in people diagnosed with intellectual disabilities. Researchers at Okayama University Hospital, Okayama University, and Asa

Updated on: March 02,2024

Examining dementia risk in adults with intellectual disability

by Okayama UniversityLittle is known about the risk factors of dementia in people diagnosed with intellectual disabilities. Researchers at Okayama University Hospital, Okayama University, and Asa

Updated on:March 02,2024