From autism to Alzheimer's: A large-scale animal study links brain pH changes to wide-ranging cognitive issues

byFujita Health UniversityIncreased brain lactate levels correlated with decreased pH are associated with poor working memory. Credit: eLife (2024). DOI: 10.7554/eLife.89376.3A global collaborat

Updated on: March 28,2024

From autism to Alzheimer's: A large-scale animal study links brain pH changes to wide-ranging cognitive issues

byFujita Health UniversityIncreased brain lactate levels correlated with decreased pH are associated with poor working memory. Credit: eLife (2024). DOI: 10.7554/eLife.89376.3A global collaborat

Updated on:March 28,2024

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on: January 15,2025

Optogenetics approach reveals how alcohol use disorder impairs cognitive flexibility

by Danielle Michaud,Texas A&M UniversityExcessive alcohol intake reduces thalamically evoked burst-pause response in DMS CINs and impairs reversal of operant conditioning. Credit:Scien

Updated on:January 15,2025

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on: September 21,2024

Critical Analysis of CDKN2A Deletion's Role in Lipid Metabolism Remodeling and Ferroptosis Sensitivity in Glioblastoma Multiforme

Updated on:September 21,2024

Alzheimer's: carriers of risk gene show brain changes in their 20s – here's why we shouldn't worry

by Mark Postans And Carl J Hodgetts,The ConversationCredit: AI-generated imageDramatic developments in genetics research and the availability of commercial genetics tests have put us in a very m

Updated on: April 20,2024

Alzheimer's: carriers of risk gene show brain changes in their 20s – here's why we shouldn't worry

by Mark Postans And Carl J Hodgetts,The ConversationCredit: AI-generated imageDramatic developments in genetics research and the availability of commercial genetics tests have put us in a very m

Updated on:April 20,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on: April 02,2024

Development of plaques in Alzheimer's disease resolved

by Ruhr-Universitaet-BochumDominik Röhr researches proteins that are altered in Alzheimer’s disease. Credit: Michael SchwettmannA team of researchers from Ruhr-Universität Bochum (RUB) and Vrije

Updated on:April 02,2024

Brain training activity linked to reduced dementia risk

by Alzheimer's Research UKFlorida researchers have presented results from a 10-year study into the effects of 'brain training' activities on healthy older people. The study found that

Updated on: March 07,2024

Brain training activity linked to reduced dementia risk

by Alzheimer's Research UKFlorida researchers have presented results from a 10-year study into the effects of 'brain training' activities on healthy older people. The study found that

Updated on:March 07,2024

Shorter white blood cell telomeres linked to higher dementia risk

by British Medical JournalHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShorter telomeres on the ends of white blood cell chromosomes may signal a heightened

Updated on: March 02,2024

Shorter white blood cell telomeres linked to higher dementia risk

by British Medical JournalHuman chromosomes (grey) capped by telomeres (white). Credit: PD-NASA; PD-USGOV-NASAShorter telomeres on the ends of white blood cell chromosomes may signal a heightened

Updated on:March 02,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on: March 07,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on:March 07,2024

Gut protein may protect brain cells in Parkinson's disease

by Moriah Cunningham,Thomas Jefferson UniversityFunctional GUCY2C protein and mRNA are expressed by DA neurons within the SNpc.aSchematic of mice used for analyses.b–dImm

Updated on: July 31,2024

Gut protein may protect brain cells in Parkinson's disease

by Moriah Cunningham,Thomas Jefferson UniversityFunctional GUCY2C protein and mRNA are expressed by DA neurons within the SNpc.aSchematic of mice used for analyses.b–dImm

Updated on:July 31,2024

A sense of touch: ASICs are the receptor for a proton synaptic messenger between Merkel cells and an afferent nerve

by Jeff Hansen,University of Alabama at BirminghamCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.01.018Transduction is the changing of one form of energy into another, such as a spo

Updated on: March 13,2024

A sense of touch: ASICs are the receptor for a proton synaptic messenger between Merkel cells and an afferent nerve

by Jeff Hansen,University of Alabama at BirminghamCredit:Neuron(2024). DOI: 10.1016/j.neuron.2024.01.018Transduction is the changing of one form of energy into another, such as a spo

Updated on:March 13,2024

Understanding removal of brain fluid provides avenue for Alzheimer's treatment

by Alzheimer's Research UKResearchers in Switzerland have investigated the way fluid is removed from around the brain. Finding a new pathway for its removal, their work may signal a paradigm

Updated on: March 07,2024

Understanding removal of brain fluid provides avenue for Alzheimer's treatment

by Alzheimer's Research UKResearchers in Switzerland have investigated the way fluid is removed from around the brain. Finding a new pathway for its removal, their work may signal a paradigm

Updated on:March 07,2024

Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds

by Sarah L. Spaulding,Yale UniversitySystemic sclerosis study participants before and after treatment with hyaluronic acid filler. Credit:JAAD Case Reports(2024). DOI: 10.1016/j.jdcr

Updated on: August 01,2024

Hyaluronic acid lip fillers safe for patients with systemic sclerosis, study finds

by Sarah L. Spaulding,Yale UniversitySystemic sclerosis study participants before and after treatment with hyaluronic acid filler. Credit:JAAD Case Reports(2024). DOI: 10.1016/j.jdcr

Updated on:August 01,2024