Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Unraveling the neural circuit behind reduced food intake in high temperatures

byKarolinska InstitutetAcute heat reduces food intake and selectively activates α-tanycytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07232-3In a study recentlypublished&nb

Updated on: April 28,2024

Unraveling the neural circuit behind reduced food intake in high temperatures

byKarolinska InstitutetAcute heat reduces food intake and selectively activates α-tanycytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07232-3In a study recentlypublished&nb

Updated on:April 28,2024

MS changes the microbiome subtly but similarly, whether in US or Asia

by Kim Krieger,University of ConnecticutDisruption of Bacteroides-Prevotella correlative network in MS. a, b Correlations shared between MS and controls. c Correlations that are unique in contro

Updated on: August 08,2024

MS changes the microbiome subtly but similarly, whether in US or Asia

by Kim Krieger,University of ConnecticutDisruption of Bacteroides-Prevotella correlative network in MS. a, b Correlations shared between MS and controls. c Correlations that are unique in contro

Updated on:August 08,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on: April 07,2024

The molecular mechanisms of Alzheimer's

by Pacific Northwest National LaboratoryFigure 1 in the paper outlines the quantitative proteomic pipeline for O-GlcNAc analysis. stochastic kinetic simulations (red) and simulations using the co

Updated on:April 07,2024

How are 'super agers' protected from Alzheimer's and mental decline?

by Alan Mozes Healthday Reporter(HealthDay)—Some older folks are still sharp as tacks and dementia-free well into their 80s and beyond. Now German researchers have uncovered a possible reason why: The

Updated on: March 13,2024

How are 'super agers' protected from Alzheimer's and mental decline?

by Alan Mozes Healthday Reporter(HealthDay)—Some older folks are still sharp as tacks and dementia-free well into their 80s and beyond. Now German researchers have uncovered a possible reason why: The

Updated on:March 13,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on: November 22,2024

New drug targets for Alzheimer's identified from cerebrospinal fluid

by Mark Reynolds,Washington University School of MedicineCellular localization of immune and lysosomal proteins. Credit:Nature Genetics(2024). DOI: 10.1038/s41588-024-01972-8A multit

Updated on:November 22,2024

PTSD may double risk of dementia

by University College LondonCredit: CC0 Public DomainPeople who have experienced post-traumatic stress disorder (PTSD) are up to twice as likely to develop dementia later in life, according to a

Updated on: May 13,2024

PTSD may double risk of dementia

by University College LondonCredit: CC0 Public DomainPeople who have experienced post-traumatic stress disorder (PTSD) are up to twice as likely to develop dementia later in life, according to a

Updated on:May 13,2024

Brain plasticity promotes worsening of epileptic seizures

by Erin Digitale,Stanford University Medical CenterCredit: Monstera Production from PexelsEpileptic seizures worsen via the same mechanism by which practice makes perfect, a new study from the S

Updated on: February 21,2024

Brain plasticity promotes worsening of epileptic seizures

by Erin Digitale,Stanford University Medical CenterCredit: Monstera Production from PexelsEpileptic seizures worsen via the same mechanism by which practice makes perfect, a new study from the S

Updated on:February 21,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on: May 11,2024

Dementia researchers call for urgent action to prevent setbacks in treatment search

by Alzheimer's Research UKCredit: CC0 Public DomainNearly 300 researchers have called for urgent government action to prevent a major setback to the search for new dementia treatments as a re

Updated on:May 11,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on: April 06,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on:April 06,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on: July 31,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on:July 31,2024

How humans continuously adapt while walking stably

byMassachusetts Institute of TechnologyA hierarchical framework for locomotor adaptation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53416-wResearchers have develope

Updated on: January 15,2025

How humans continuously adapt while walking stably

byMassachusetts Institute of TechnologyA hierarchical framework for locomotor adaptation. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53416-wResearchers have develope

Updated on:January 15,2025