GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on: March 30,2024

GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on:March 30,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on: July 01,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on:July 01,2024

Neuronal diversity impacts the brain's information processing

by Melissa Rohman,Northwestern UniversitySpike threshold heterogeneity affects the function generation properties of spiking neural networks. (A) Reservoir computing architecture used for functi

Updated on: March 13,2024

Neuronal diversity impacts the brain's information processing

by Melissa Rohman,Northwestern UniversitySpike threshold heterogeneity affects the function generation properties of spiking neural networks. (A) Reservoir computing architecture used for functi

Updated on:March 13,2024

Working-age people living with dementia experience inadequate guidance and counselling

by University of Eastern FinlandCredit: Unsplash/CC0 Public DomainThe right of working-age people living with dementia to receive adequate and timely guidance and counseling is not realized prope

Updated on: June 11,2024

Working-age people living with dementia experience inadequate guidance and counselling

by University of Eastern FinlandCredit: Unsplash/CC0 Public DomainThe right of working-age people living with dementia to receive adequate and timely guidance and counseling is not realized prope

Updated on:June 11,2024

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on: February 28,2024

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on:February 28,2024

Detecting diminished dopamine-firing cells inside brain could reveal earliest signs of Alzheimer's

by University of SheffieldPET scan of a human brain with Alzheimer's disease. Credit: public domainA new link between diminished input from dopamine-firing cells deep inside the brain and the

Updated on: June 20,2024

Detecting diminished dopamine-firing cells inside brain could reveal earliest signs of Alzheimer's

by University of SheffieldPET scan of a human brain with Alzheimer's disease. Credit: public domainA new link between diminished input from dopamine-firing cells deep inside the brain and the

Updated on:June 20,2024

One in three people born in 2015 will develop dementia, new analysis shows

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Alzheimer's Research UK has renewed its call for urgent action on

Updated on: February 26,2024

One in three people born in 2015 will develop dementia, new analysis shows

by Alzheimer's Research UKDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Alzheimer's Research UK has renewed its call for urgent action on

Updated on:February 26,2024

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on: February 26,2024

Reducing harmful proteins in the fight against dementia

by Jacqueline Pumphrey, Oxford Science Blog,Oxford UniversityWe probably all know someone who has dementia. By 2025, there will be 1 million people affected by it in the UK. Alzheimer's dise

Updated on:February 26,2024

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on: April 02,2024

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on:April 02,2024

Older adults with dementia exhibit financial 'symptoms' up to six years before diagnosis

by Johns Hopkins University Bloomberg School of Public HealthCredit: CC0 Public DomainA new study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the Federal Reserve

Updated on: June 11,2024

Older adults with dementia exhibit financial 'symptoms' up to six years before diagnosis

by Johns Hopkins University Bloomberg School of Public HealthCredit: CC0 Public DomainA new study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the Federal Reserve

Updated on:June 11,2024

Insulin signaling failures in the brain linked to Alzheimer's disease

by Joslin Diabetes CenterC. Ronald Kahn, Chief Academic Officer at Joslin Diabetes Center, and Mary K. Iacocca Professor of Medicine at Harvard Medical School Credit: Joslin CommunicationsScienti

Updated on: May 18,2024

Insulin signaling failures in the brain linked to Alzheimer's disease

by Joslin Diabetes CenterC. Ronald Kahn, Chief Academic Officer at Joslin Diabetes Center, and Mary K. Iacocca Professor of Medicine at Harvard Medical School Credit: Joslin CommunicationsScienti

Updated on:May 18,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on: May 18,2024

Immune cells in the brain play key role in relationship between gut microbes and b-amyloid deposits

by University of Chicago Medical CenterMicroglia in the brain of male mice with Alzheimer's Disease have a “neurodegenerative” appearance and is associated with amyloid beta plaques in the br

Updated on:May 18,2024