GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on: March 30,2024

GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on:March 30,2024

Odor biomarker for Alzheimer's disease

by Monell Chemical Senses CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study from the Monell Center, the U.S. Department of Agricultu

Updated on: February 27,2024

Odor biomarker for Alzheimer's disease

by Monell Chemical Senses CenterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.A new study from the Monell Center, the U.S. Department of Agricultu

Updated on:February 27,2024

Protein droplets likely don't cause Parkinson's, study suggests

byPaul Scherrer InstituteCredit:Advanced Science(2024). DOI: 10.1002/advs.202308279Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological h

Updated on: July 17,2024

Protein droplets likely don't cause Parkinson's, study suggests

byPaul Scherrer InstituteCredit:Advanced Science(2024). DOI: 10.1002/advs.202308279Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological h

Updated on:July 17,2024

Lithium shows promise in treating autism-related symptoms in mouse study

byInstitute for Basic ScienceLithium restored microcephaly, abnormal synaptic function, and communication issues in mice with Dyrk1a deficiency, a gene associated with autism and Dyrk1a syndrome

Updated on: January 18,2025

Lithium shows promise in treating autism-related symptoms in mouse study

byInstitute for Basic ScienceLithium restored microcephaly, abnormal synaptic function, and communication issues in mice with Dyrk1a deficiency, a gene associated with autism and Dyrk1a syndrome

Updated on:January 18,2025

White matter integrity disrupted in people with Alzheimer's gene mutation

by Radiological Society of North AmericaCortical areas involved with each of the three distributed cortical association networks analyzed are displayed on an inflated brain surface, viewed from t

Updated on: April 20,2024

White matter integrity disrupted in people with Alzheimer's gene mutation

by Radiological Society of North AmericaCortical areas involved with each of the three distributed cortical association networks analyzed are displayed on an inflated brain surface, viewed from t

Updated on:April 20,2024

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on: June 18,2024

Computational techniques explore 'the dark side of amyloid aggregation in the brain'

by Jianhan Chen,University of Massachusetts AmherstPET scan of a human brain with Alzheimer's disease. Credit: public domainAs physicians and families know too well, though Alzheimer's d

Updated on:June 18,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on: July 01,2024

Decoding the genetics that drive disease

by University of South AustraliaSome human genes traditionally labeled as 'bad' are not always what they seem. Credit: Gerd Altmann from PixabayFrom Alzheimer's to obesity, life can c

Updated on:July 01,2024

Modulating brain's stress circuity might prevent Alzheimer's disease

by University of California - San DiegoDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In a novel animal study design that mimicked human clinical t

Updated on: February 27,2024

Modulating brain's stress circuity might prevent Alzheimer's disease

by University of California - San DiegoDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.In a novel animal study design that mimicked human clinical t

Updated on:February 27,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on: February 26,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on:February 26,2024

Antihypertensive drugs are effective in hereditary cerebral small vessel disease

by Niigata UniversityTherapeutic effect of candesartan on cerebral arteriopathy via inhibition of matrisome protein accumulation. Credit: Niigata UniversityOur brains have small arteries that perform

Updated on: June 24,2024

Antihypertensive drugs are effective in hereditary cerebral small vessel disease

by Niigata UniversityTherapeutic effect of candesartan on cerebral arteriopathy via inhibition of matrisome protein accumulation. Credit: Niigata UniversityOur brains have small arteries that perform

Updated on:June 24,2024

Study shows that 'transcendent' thinking may grow teens' brains over time

byUniversity of Southern CaliforniaDepiction of coronal, sagittal, and axial views of the group-level default mode network (DMN; top) and left executive control network (left ECN; bottom) maps,

Updated on: March 28,2024

Study shows that 'transcendent' thinking may grow teens' brains over time

byUniversity of Southern CaliforniaDepiction of coronal, sagittal, and axial views of the group-level default mode network (DMN; top) and left executive control network (left ECN; bottom) maps,

Updated on:March 28,2024

Unraveling the neural circuit behind reduced food intake in high temperatures

byKarolinska InstitutetAcute heat reduces food intake and selectively activates α-tanycytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07232-3In a study recentlypublished&nb

Updated on: April 28,2024

Unraveling the neural circuit behind reduced food intake in high temperatures

byKarolinska InstitutetAcute heat reduces food intake and selectively activates α-tanycytes. Credit:Nature(2024). DOI: 10.1038/s41586-024-07232-3In a study recentlypublished&nb

Updated on:April 28,2024