HIV drug shown to help protect against build-up of dementia-related proteins in mouse brains

by University of CambridgeGraphical Abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.04.006Cambridge scientists have shown how the brain's ability to clear out toxic prot

Updated on: March 30,2024

HIV drug shown to help protect against build-up of dementia-related proteins in mouse brains

by University of CambridgeGraphical Abstract. Credit:Neuron(2023). DOI: 10.1016/j.neuron.2023.04.006Cambridge scientists have shown how the brain's ability to clear out toxic prot

Updated on:March 30,2024

GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on: March 30,2024

GluN3A knockout mouse: Alternative model for Alzheimer's neurodegeneration

by Emory UniversityGluN3A (in the diagram, NR3) is an inhibitory subunit within NMDA receptor assemblies, which function as glutamate-gated cation channels. GluN3A is a key regulator of neuronal

Updated on:March 30,2024

Protein droplets likely don't cause Parkinson's, study suggests

byPaul Scherrer InstituteCredit:Advanced Science(2024). DOI: 10.1002/advs.202308279Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological h

Updated on: July 17,2024

Protein droplets likely don't cause Parkinson's, study suggests

byPaul Scherrer InstituteCredit:Advanced Science(2024). DOI: 10.1002/advs.202308279Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological h

Updated on:July 17,2024

Alzheimer's gene-mapping project proposed in New York state

A proposed project to map the genes of 1 million people in New York living with or at risk for Alzheimer disease was announced Friday by Gov. Andrew Cuomo.He said the five years of data collected by t

Updated on: April 20,2024

Alzheimer's gene-mapping project proposed in New York state

A proposed project to map the genes of 1 million people in New York living with or at risk for Alzheimer disease was announced Friday by Gov. Andrew Cuomo.He said the five years of data collected by t

Updated on:April 20,2024

Study shows that 'transcendent' thinking may grow teens' brains over time

byUniversity of Southern CaliforniaDepiction of coronal, sagittal, and axial views of the group-level default mode network (DMN; top) and left executive control network (left ECN; bottom) maps,

Updated on: March 28,2024

Study shows that 'transcendent' thinking may grow teens' brains over time

byUniversity of Southern CaliforniaDepiction of coronal, sagittal, and axial views of the group-level default mode network (DMN; top) and left executive control network (left ECN; bottom) maps,

Updated on:March 28,2024

Brain cell membranes' lipids may play big role in Alzheimer's progression

by American Institute of PhysicsLinks between lipid imbalance and disease have been established, in which lipid changes increase the formation of amyloid plaques, a hallmark of Alzheimer's di

Updated on: May 18,2024

Brain cell membranes' lipids may play big role in Alzheimer's progression

by American Institute of PhysicsLinks between lipid imbalance and disease have been established, in which lipid changes increase the formation of amyloid plaques, a hallmark of Alzheimer's di

Updated on:May 18,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on: April 06,2024

Mitochondrial roles in antiviral immunity modify manifestations of neurological diseases

by University of HelsinkiSchematic of antiviral innate immune signaling responses to viral PAMPs. Credit:Nature(2024). DOI: 10.1038/s41586-024-07260-zA multidisciplinary team of scien

Updated on:April 06,2024

Systemic sclerosis is on the rise in Quebec, especially in children, study finds

by Claire Loewen,McGill UniversityAge-standardized incidence rates (ASIR) over time (1996–2019) for females, males, and both. The gray shading depicts the 95% confidence intervals for the annual

Updated on: July 17,2024

Systemic sclerosis is on the rise in Quebec, especially in children, study finds

by Claire Loewen,McGill UniversityAge-standardized incidence rates (ASIR) over time (1996–2019) for females, males, and both. The gray shading depicts the 95% confidence intervals for the annual

Updated on:July 17,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on: March 07,2024

Structural analysis of relevant drug targets for Alzheimer's disease

by Bentham Science PublishersAlzheimer's Disease (AD) is classified as a neurodegenerative non-curable disease that affects millions worldwide. Current drugs have side effects that are significant

Updated on:March 07,2024

Genetic 'whiteout' offers hope to children living with dementia

by Murdoch UniversityChildren living with dementia have the same symptoms as adults with dementia, in that they are losing memories and face a gradual decline in health, with most not reaching ad

Updated on: June 14,2024

Genetic 'whiteout' offers hope to children living with dementia

by Murdoch UniversityChildren living with dementia have the same symptoms as adults with dementia, in that they are losing memories and face a gradual decline in health, with most not reaching ad

Updated on:June 14,2024

Study reveals direct gut-brain communication via vagus nerve

Updated on: March 05,2025

Study reveals direct gut-brain communication via vagus nerve

Updated on:March 05,2025

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on: April 25,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on:April 25,2024