The middle-aged brain changes a lot—and it's key to understanding dementia

by Sebastian Dohm-Hansen Allard and Yvonne Nolan,The ConversationCredit: CC0 Public DomainOur brains change more rapidly at various times of our lives, as though life's clock was ticking fas

Updated on: March 28,2024

The middle-aged brain changes a lot—and it's key to understanding dementia

by Sebastian Dohm-Hansen Allard and Yvonne Nolan,The ConversationCredit: CC0 Public DomainOur brains change more rapidly at various times of our lives, as though life's clock was ticking fas

Updated on:March 28,2024

Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on: May 18,2024

Waste management in the brain may shed light on dementia

by Jim Shelton,Yale UniversityFig. 1: CSF flow speed becomes hyperdynamic with severe CAA. Credit:Nature Aging(2022). DOI: 10.1038/s43587-022-00181-4A new study suggests that a contr

Updated on:May 18,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on: March 07,2024

Treponema denticola found to induce Alzheimer-like tau hyperphosphorylation in mice

by International & American Associations for Dental ResearchA study investigating the role of Treponema denticola (T. denticola) in Alzheimer's disease (AD) pathogenesis will be presented by Z

Updated on:March 07,2024

New insights into causes of loss of orientation in dementia

by University of ExeterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.New research has revealed how disease-associated changes in two interlinked n

Updated on: February 27,2024

New insights into causes of loss of orientation in dementia

by University of ExeterDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.New research has revealed how disease-associated changes in two interlinked n

Updated on:February 27,2024

Newly discovered mechanism in mitochondria could lead to new treatment for muscle disorders

byUniversity of CopenhagenCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-54183-4Researchers have discovered a mechanism in our cells that is essential to energy producti

Updated on: December 23,2024

Newly discovered mechanism in mitochondria could lead to new treatment for muscle disorders

byUniversity of CopenhagenCredit:Nature Communications(2024). DOI: 10.1038/s41467-024-54183-4Researchers have discovered a mechanism in our cells that is essential to energy producti

Updated on:December 23,2024

Can online therapy reduce distress in dementia carers?

by University of ExeterCaring is both rewarding and demanding. Credit: University of ExeterA new study is inviting people who care for someone with dementia to help investigate whether an online

Updated on: March 09,2024

Can online therapy reduce distress in dementia carers?

by University of ExeterCaring is both rewarding and demanding. Credit: University of ExeterA new study is inviting people who care for someone with dementia to help investigate whether an online

Updated on:March 09,2024

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on: June 14,2024

Machine learning gives nuanced view of Alzheimer's stages

by David Nutt,Cornell UniversityFeed-forward, fully-connected neural network architecture. Nonlinear models have rectified linear units (ReLU) between layers. Final layer implements a soft-max.

Updated on:June 14,2024

Alzheimer's disease and type 2 diabetes: Synthetic peptides may suppress formation of harmful amyloid aggregates

by Technical University MunichProposed mechanism and hypothetical models of IAPP/ACM nanofiber co-assembly versus IAPP amyloid self-assembly. The lower part, IAPP self-assembly into toxic oligome

Updated on: April 08,2024

Alzheimer's disease and type 2 diabetes: Synthetic peptides may suppress formation of harmful amyloid aggregates

by Technical University MunichProposed mechanism and hypothetical models of IAPP/ACM nanofiber co-assembly versus IAPP amyloid self-assembly. The lower part, IAPP self-assembly into toxic oligome

Updated on:April 08,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on: April 25,2024

Certain genetic variant in Alzheimer's disease linked to African ancestry

by Elana GotkineFor individuals of African ancestry, theAPOEε3 R145C missense variant is associated with an increased risk for Alzheimer disease (AD), according to a study published in the

Updated on:April 25,2024

Active mind, body may only do so much against Alzheimer's

(HealthDay)—There's plenty of evidence suggesting that people who are active socially, intellectually and physically may stave off Alzheimer's disease. However, a new study shows those efforts

Updated on: February 28,2024

Active mind, body may only do so much against Alzheimer's

(HealthDay)—There's plenty of evidence suggesting that people who are active socially, intellectually and physically may stave off Alzheimer's disease. However, a new study shows those efforts

Updated on:February 28,2024

Imaging probe to visualize Alzheimer's disease-related gamma-secretase in the brain

by Massachusetts General HospitalCredit: Unsplash/CC0 Public DomainScientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer's diseas

Updated on: May 06,2024

Imaging probe to visualize Alzheimer's disease-related gamma-secretase in the brain

by Massachusetts General HospitalCredit: Unsplash/CC0 Public DomainScientists at the Massachusetts General Hospital (MGH) have developed a molecular imaging probe to reveal Alzheimer's diseas

Updated on:May 06,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024