Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Study investigates how effective multiple sclerosis medications are across racial and ethnic groups

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainFor people with relapsing-remitting multiple sclerosis (MS), a new study has found that the drug ofatumumab is more effective tha

Updated on: July 31,2024

Study investigates how effective multiple sclerosis medications are across racial and ethnic groups

byAmerican Academy of NeurologyCredit: Unsplash/CC0 Public DomainFor people with relapsing-remitting multiple sclerosis (MS), a new study has found that the drug ofatumumab is more effective tha

Updated on:July 31,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on: July 17,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on:July 17,2024

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on: March 19,2024

Alzheimer's disease and the holidays

by Graciela Gutierrez,Baylor College of MedicineCredit: Unsplash/CC0 Public DomainThe holidays can be a special time, but may present challenges for those with dementia and their loved ones. Tra

Updated on:March 19,2024

Researchers study connection between cholesterol level and cognitive decline in old age

by Heidelberg UniversityChanges in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University'

Updated on: February 26,2024

Researchers study connection between cholesterol level and cognitive decline in old age

by Heidelberg UniversityChanges in lifestyle could reduce the risk of developing Alzheimer's disease. That was the conclusion of a study conducted by researchers of Heidelberg University'

Updated on:February 26,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on: February 05,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on:February 05,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on: November 07,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on:November 07,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024

Alzheimer's progression tied to stress-induced microglial lipid release

byCUNY Advanced Science Research CenterElectron micrographs show typical microglia in the prefrontal cortex of a 92-year-old healthy female (left) and dark microglia of a 91-year-old female pati

Updated on: January 18,2025

Alzheimer's progression tied to stress-induced microglial lipid release

byCUNY Advanced Science Research CenterElectron micrographs show typical microglia in the prefrontal cortex of a 92-year-old healthy female (left) and dark microglia of a 91-year-old female pati

Updated on:January 18,2025

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on: November 06,2024

Could 'zombie cells' in the skin be aging your brain too?

by Mayo Clinic News NetworkCredit: Pixabay/CC0 Public DomainMayo Clinic researchers have found that senescent cells—non-dividing "zombie" cells—accumulate in the skin as people age and may i

Updated on:November 06,2024

Ultrasound therapy shows promise as a treatment for Alzheimer's disease

by University of QueenslandGraphical representation of the findings of this study: Improved memory, enhanced functional connectivity and an altered proteome were found in APP23 mice in the absenc

Updated on: April 06,2024

Ultrasound therapy shows promise as a treatment for Alzheimer's disease

by University of QueenslandGraphical representation of the findings of this study: Improved memory, enhanced functional connectivity and an altered proteome were found in APP23 mice in the absenc

Updated on:April 06,2024