COVID-19 infection in crucial brain regions may lead to accelerated brain aging

by Houston MethodistThe interaction of SARS-CoV-2 with olfactory cilia for entering the central nervous system (CNS). A) Different layers of cells in the nasal cavity that contain receptors for t

Updated on: February 21,2024

COVID-19 infection in crucial brain regions may lead to accelerated brain aging

by Houston MethodistThe interaction of SARS-CoV-2 with olfactory cilia for entering the central nervous system (CNS). A) Different layers of cells in the nasal cavity that contain receptors for t

Updated on:February 21,2024

New blood test for Alzheimer's developed

by Margareta G. Kubista,University of GothenburgCredit: CC0 Public DomainA new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of

Updated on: April 18,2024

New blood test for Alzheimer's developed

by Margareta G. Kubista,University of GothenburgCredit: CC0 Public DomainA new blood test for Alzheimer's disease has been developed under the leadership of researchers at the University of

Updated on:April 18,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on: April 16,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on:April 16,2024

Study reveals how key brain regions regulate inhibitory actions, paving way for impulse control disorder treatment

by Juntendo University Research Promotion CenterExperiment overview. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54564-9A pioneering study from Japan meticulously maps the

Updated on: December 17,2024

Study reveals how key brain regions regulate inhibitory actions, paving way for impulse control disorder treatment

by Juntendo University Research Promotion CenterExperiment overview. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54564-9A pioneering study from Japan meticulously maps the

Updated on:December 17,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024

AEDs tied to higher pneumonia risk in Alzheimer patients

(HealthDay)—Antiepileptic drug (AED) use may increase the risk for pneumonia in patients with Alzheimer disease (AD), according to a study recently published in theJournal of Alzheimer's Dis

Updated on: March 19,2024

AEDs tied to higher pneumonia risk in Alzheimer patients

(HealthDay)—Antiepileptic drug (AED) use may increase the risk for pneumonia in patients with Alzheimer disease (AD), according to a study recently published in theJournal of Alzheimer's Dis

Updated on:March 19,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on: April 20,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on:April 20,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on: February 05,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on:February 05,2024

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on: February 26,2024

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on:February 26,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on: April 08,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on:April 08,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on: April 16,2024

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on:April 16,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on: April 07,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on:April 07,2024