Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on: February 28,2024

Blocking inflammation prevents cell death, improves memory in Alzheimer's disease

by University of California, IrvineA brain tissue sample from Kim Green’s study show microglia (red) and plaques (green). Credit: Green lab / UCIUsing a drug compound created to treat cance

Updated on:February 28,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on: April 16,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on:April 16,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on: April 07,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on:April 07,2024

Global study could change how children with multiple sclerosis are treated

by Melbourne HealthCredit: CC0 Public DomainA new study—the largest of its kind globally—has found children with multiple sclerosis (MS) have better outcomes if treated early and with the same high-ef

Updated on: March 28,2024

Global study could change how children with multiple sclerosis are treated

by Melbourne HealthCredit: CC0 Public DomainA new study—the largest of its kind globally—has found children with multiple sclerosis (MS) have better outcomes if treated early and with the same high-ef

Updated on:March 28,2024

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on: March 30,2024

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on:March 30,2024

Student-athletes with self-reported autism more likely to score low on common concussion test

by Saint Joseph's UniversityCredit: Pixabay/CC0 Public DomainSchools and colleges across the country rely on Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) evaluations to

Updated on: March 30,2024

Student-athletes with self-reported autism more likely to score low on common concussion test

by Saint Joseph's UniversityCredit: Pixabay/CC0 Public DomainSchools and colleges across the country rely on Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) evaluations to

Updated on:March 30,2024

Care home study highlights poor care for dementia residents with hearing problems

by Mike Addelman,University of ManchesterCredit: Unsplash/CC0 Public DomainHard of hearing people with dementia are not receiving the care they desperately need, according to a new study by Univ

Updated on: March 02,2024

Care home study highlights poor care for dementia residents with hearing problems

by Mike Addelman,University of ManchesterCredit: Unsplash/CC0 Public DomainHard of hearing people with dementia are not receiving the care they desperately need, according to a new study by Univ

Updated on:March 02,2024

COVID-19 infection in crucial brain regions may lead to accelerated brain aging

by Houston MethodistThe interaction of SARS-CoV-2 with olfactory cilia for entering the central nervous system (CNS). A) Different layers of cells in the nasal cavity that contain receptors for t

Updated on: February 21,2024

COVID-19 infection in crucial brain regions may lead to accelerated brain aging

by Houston MethodistThe interaction of SARS-CoV-2 with olfactory cilia for entering the central nervous system (CNS). A) Different layers of cells in the nasal cavity that contain receptors for t

Updated on:February 21,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Experimental drug targeting Alzheimer's disease shows anti-aging effects

by Salk InstituteAs mice age, those treated with J147 (right) showed improved physiology, memory and appearance that more closely resembled younger mice. Credit: Salk Institute for Biological Stu

Updated on: February 27,2024

Experimental drug targeting Alzheimer's disease shows anti-aging effects

by Salk InstituteAs mice age, those treated with J147 (right) showed improved physiology, memory and appearance that more closely resembled younger mice. Credit: Salk Institute for Biological Stu

Updated on:February 27,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on: April 20,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on:April 20,2024