New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on: July 11,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on:July 11,2024

Brain circuit strength predicts a child's ability to understand numbers

by Society for NeuroscienceHippocampal-parietal functional circuits predict number sense training gains. Functional connectivity of the (A) left and (B) right hippocampus with the left intraparie

Updated on: February 21,2024

Brain circuit strength predicts a child's ability to understand numbers

by Society for NeuroscienceHippocampal-parietal functional circuits predict number sense training gains. Functional connectivity of the (A) left and (B) right hippocampus with the left intraparie

Updated on:February 21,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on: April 08,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on:April 08,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on: April 07,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on:April 07,2024

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on: March 30,2024

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on:March 30,2024

Risk for dementia reduced in association with antihypertensive use

by Elana GotkineAntihypertensive use is associated with a reduced risk for dementia compared with untreated hypertension, according to research published online Sept. 12 inJAMA Network Open.Matt

Updated on: March 02,2024

Risk for dementia reduced in association with antihypertensive use

by Elana GotkineAntihypertensive use is associated with a reduced risk for dementia compared with untreated hypertension, according to research published online Sept. 12 inJAMA Network Open.Matt

Updated on:March 02,2024

Autophagy malfunction study moves a step closer to understanding Rett syndrome

Updated on: April 17,2025

Autophagy malfunction study moves a step closer to understanding Rett syndrome

Updated on:April 17,2025

New data resource for dementia research

by Oxford UniversityAn Oxford University-led research programme has launched a new system to help dementia researchers make the most of existing study data. The Dementias Platform UK's new&nb

Updated on: February 26,2024

New data resource for dementia research

by Oxford UniversityAn Oxford University-led research programme has launched a new system to help dementia researchers make the most of existing study data. The Dementias Platform UK's new&nb

Updated on:February 26,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on: February 05,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on:February 05,2024

Education, intelligence may protect cognition, but don't prevent Alzheimer's disease

by Johns Hopkins University School of MedicinePet scan. Credit: Rebecca GottesmanIn a search for clues to what may delay or prevent Alzheimer's disease, Johns Hopkins Medicine scientists repo

Updated on: June 24,2024

Education, intelligence may protect cognition, but don't prevent Alzheimer's disease

by Johns Hopkins University School of MedicinePet scan. Credit: Rebecca GottesmanIn a search for clues to what may delay or prevent Alzheimer's disease, Johns Hopkins Medicine scientists repo

Updated on:June 24,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on: March 02,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on:March 02,2024