Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on: May 06,2024

Dementia and COVID-19: Determinants of infection and mortality

by IOS PressFactors associated with 60-day mortality in dementia patients infected with SARS-CoV-2. Credit:Journal of Alzheimer's Disease(2022). DOI: 10.3233/JAD-220369The elderly

Updated on:May 06,2024

Autophagy malfunction study moves a step closer to understanding Rett syndrome

Updated on: April 17,2025

Autophagy malfunction study moves a step closer to understanding Rett syndrome

Updated on:April 17,2025

COVID-19 infection in crucial brain regions may lead to accelerated brain aging

by Houston MethodistThe interaction of SARS-CoV-2 with olfactory cilia for entering the central nervous system (CNS). A) Different layers of cells in the nasal cavity that contain receptors for t

Updated on: February 21,2024

COVID-19 infection in crucial brain regions may lead to accelerated brain aging

by Houston MethodistThe interaction of SARS-CoV-2 with olfactory cilia for entering the central nervous system (CNS). A) Different layers of cells in the nasal cavity that contain receptors for t

Updated on:February 21,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on: November 07,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on:November 07,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Care home study highlights poor care for dementia residents with hearing problems

by Mike Addelman,University of ManchesterCredit: Unsplash/CC0 Public DomainHard of hearing people with dementia are not receiving the care they desperately need, according to a new study by Univ

Updated on: March 02,2024

Care home study highlights poor care for dementia residents with hearing problems

by Mike Addelman,University of ManchesterCredit: Unsplash/CC0 Public DomainHard of hearing people with dementia are not receiving the care they desperately need, according to a new study by Univ

Updated on:March 02,2024

AEDs tied to higher pneumonia risk in Alzheimer patients

(HealthDay)—Antiepileptic drug (AED) use may increase the risk for pneumonia in patients with Alzheimer disease (AD), according to a study recently published in theJournal of Alzheimer's Dis

Updated on: March 19,2024

AEDs tied to higher pneumonia risk in Alzheimer patients

(HealthDay)—Antiepileptic drug (AED) use may increase the risk for pneumonia in patients with Alzheimer disease (AD), according to a study recently published in theJournal of Alzheimer's Dis

Updated on:March 19,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

Middle-age obesity may be caused by changes in the shapes of neurons in the brain

by Nagoya UniversityShortening of MC4R+primary cilia in the hypothalamus of the brain leads to middle-age obesity. Credit: Kazuhiro NakamuraNagoya University researchers and their colleague

Updated on: March 19,2024

Middle-age obesity may be caused by changes in the shapes of neurons in the brain

by Nagoya UniversityShortening of MC4R+primary cilia in the hypothalamus of the brain leads to middle-age obesity. Credit: Kazuhiro NakamuraNagoya University researchers and their colleague

Updated on:March 19,2024

Memory games: Eating well to remember

by University of Technology, SydneyCredit: CC0 Public DomainA healthy diet is essential to living well, but as we age, should we change what we eat?UTS research fellow Dr. Luna Xu has studied dat

Updated on: June 20,2024

Memory games: Eating well to remember

by University of Technology, SydneyCredit: CC0 Public DomainA healthy diet is essential to living well, but as we age, should we change what we eat?UTS research fellow Dr. Luna Xu has studied dat

Updated on:June 20,2024

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on: March 30,2024

Overlapping mechanisms in HIV cognitive disorders and Alzheimer's disease

by Society for NeuroscienceAβ oligomers are elevated in the brains of HIV(+) cases. Paraffin-embedded tissue sections from hippocampus of HIV(-) and HIV(+) individuals were prepared for immunoflu

Updated on:March 30,2024