Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on: April 16,2024

Alzheimer's drug development pipeline: Promising therapies, pharma investment drive momentum in clinical trials

by University of Nevada, Las VegasAgents in clinical trials for treatment of Alzheimer's disease in 2023 (from ClinicalTrials.gov as of the index date of January 1, 2023). The inner ring show

Updated on:April 16,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on: July 31,2024

New study shows promising diagnosis of multiple sclerosis from images of the eye

byDurham UniversitySaliency maps generated for eight SLO images and OCT thickness maps of the total retina of (A) HC and (B) MS subjects from the test dataset when the best-performing model trai

Updated on:July 31,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on: March 02,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on:March 02,2024

Mechanisms of phototherapy of Alzheimer's disease during sleep and wakefulness

by Frontiers JournalsPhotobiomodulation of brain cleansing of beta-amyloid during sleep. Credit: Frontiers JournalsPhotobiomodulation during sleep turns the brain into a washing machine, helping to cl

Updated on: March 02,2024

Mechanisms of phototherapy of Alzheimer's disease during sleep and wakefulness

by Frontiers JournalsPhotobiomodulation of brain cleansing of beta-amyloid during sleep. Credit: Frontiers JournalsPhotobiomodulation during sleep turns the brain into a washing machine, helping to cl

Updated on:March 02,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on: February 26,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on:February 26,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on: April 16,2024

Alzheimer's drug trial targets toxic proteases from gum disease bacteria in the brain

by Alzheimer's Research UKP. gingivalis colonies grown on blood agar. CC0 Public DomainThe pharmaceutical company, Cortexyme, Inc. has outlined a trial of potential Alzheimer's drug that

Updated on:April 16,2024

Middle-age obesity may be caused by changes in the shapes of neurons in the brain

by Nagoya UniversityShortening of MC4R+primary cilia in the hypothalamus of the brain leads to middle-age obesity. Credit: Kazuhiro NakamuraNagoya University researchers and their colleague

Updated on: March 19,2024

Middle-age obesity may be caused by changes in the shapes of neurons in the brain

by Nagoya UniversityShortening of MC4R+primary cilia in the hypothalamus of the brain leads to middle-age obesity. Credit: Kazuhiro NakamuraNagoya University researchers and their colleague

Updated on:March 19,2024

Study reveals how key brain regions regulate inhibitory actions, paving way for impulse control disorder treatment

by Juntendo University Research Promotion CenterExperiment overview. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54564-9A pioneering study from Japan meticulously maps the

Updated on: December 17,2024

Study reveals how key brain regions regulate inhibitory actions, paving way for impulse control disorder treatment

by Juntendo University Research Promotion CenterExperiment overview. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54564-9A pioneering study from Japan meticulously maps the

Updated on:December 17,2024

AEDs tied to higher pneumonia risk in Alzheimer patients

(HealthDay)—Antiepileptic drug (AED) use may increase the risk for pneumonia in patients with Alzheimer disease (AD), according to a study recently published in theJournal of Alzheimer's Dis

Updated on: March 19,2024

AEDs tied to higher pneumonia risk in Alzheimer patients

(HealthDay)—Antiepileptic drug (AED) use may increase the risk for pneumonia in patients with Alzheimer disease (AD), according to a study recently published in theJournal of Alzheimer's Dis

Updated on:March 19,2024

Memory games: Eating well to remember

by University of Technology, SydneyCredit: CC0 Public DomainA healthy diet is essential to living well, but as we age, should we change what we eat?UTS research fellow Dr. Luna Xu has studied dat

Updated on: June 20,2024

Memory games: Eating well to remember

by University of Technology, SydneyCredit: CC0 Public DomainA healthy diet is essential to living well, but as we age, should we change what we eat?UTS research fellow Dr. Luna Xu has studied dat

Updated on:June 20,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024