New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on: July 11,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on:July 11,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on: April 20,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on:April 20,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on: February 26,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on:February 26,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on: February 05,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on:February 05,2024

Strategies to generate neuronal diversity

by Zhang Nannan,Chinese Academy of SciencesStrategies for generating neuronal diversity in cerebral cortex, retina and hypothalamus. Credit: IGDBThe complexity and function of the nervous system

Updated on: February 05,2024

Strategies to generate neuronal diversity

by Zhang Nannan,Chinese Academy of SciencesStrategies for generating neuronal diversity in cerebral cortex, retina and hypothalamus. Credit: IGDBThe complexity and function of the nervous system

Updated on:February 05,2024

Combining cell therapy with approved drug shows promise for treating multiple sclerosis

byJosep Carreras Leukaemia Research InstituteCredit: Pixabay/CC0 Public DomainMultiple sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer aroun

Updated on: October 14,2024

Combining cell therapy with approved drug shows promise for treating multiple sclerosis

byJosep Carreras Leukaemia Research InstituteCredit: Pixabay/CC0 Public DomainMultiple sclerosis (MS) is a long-term disease where the immune system mistakenly attacks the protective layer aroun

Updated on:October 14,2024

Discovery adds context to Alzheimer's fight

by Paul Mayne,University of Western OntarioRobarts Research Institute scientists Vania and Marco Prado have found a gene, TRPM2, that could be a therapeutic target to assist in decreasing cognit

Updated on: February 27,2024

Discovery adds context to Alzheimer's fight

by Paul Mayne,University of Western OntarioRobarts Research Institute scientists Vania and Marco Prado have found a gene, TRPM2, that could be a therapeutic target to assist in decreasing cognit

Updated on:February 27,2024

Women with Alzheimer's-related gene lose weight more sharply after age 70

by SUNY Downstate Medical CenterResearchers led by Deborah Gustafson, PhD, MS, professor of neurology at SUNY Downstate Medical Center, have shown that women with a gene variant (APOEe4 allele) associ

Updated on: February 26,2024

Women with Alzheimer's-related gene lose weight more sharply after age 70

by SUNY Downstate Medical CenterResearchers led by Deborah Gustafson, PhD, MS, professor of neurology at SUNY Downstate Medical Center, have shown that women with a gene variant (APOEe4 allele) associ

Updated on:February 26,2024

Mouse study finds sex-based differences in how brains handle threats

Mouse study finds sex-based differences in how brains handle threatsby Claire Loewen,McGill UniversityMales and females similarly acquire threat discrimination. Credit:Nature Neuroscience&

Updated on: September 23,2024

Mouse study finds sex-based differences in how brains handle threats

Mouse study finds sex-based differences in how brains handle threatsby Claire Loewen,McGill UniversityMales and females similarly acquire threat discrimination. Credit:Nature Neuroscience&

Updated on:September 23,2024

Race of people given Alzheimer's blood tests may affect interpretation of results

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainThree experimental blood tests used to identify people in early stages of Alzheimer's disease perform differently

Updated on: June 24,2024

Race of people given Alzheimer's blood tests may affect interpretation of results

by Washington University School of MedicineCredit: Unsplash/CC0 Public DomainThree experimental blood tests used to identify people in early stages of Alzheimer's disease perform differently

Updated on:June 24,2024

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on: May 21,2024

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on:May 21,2024