A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on: March 30,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on:March 30,2024

A promising new approach to data sharing in neuroscience research

byHoward Hughes Medical InstituteOverview of Spyglass. Credit:(2024). DOI: 10.1101/2024.01.25.577295Loren Frank's HHMI lab at UCSF has pioneered an ambitious framework for sharing vast

Updated on: March 28,2024

A promising new approach to data sharing in neuroscience research

byHoward Hughes Medical InstituteOverview of Spyglass. Credit:(2024). DOI: 10.1101/2024.01.25.577295Loren Frank's HHMI lab at UCSF has pioneered an ambitious framework for sharing vast

Updated on:March 28,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Music proves to be a real hit in dementia project

by Lancaster UniversityCreative activities, such as designing musical instruments, can improve the quality of life of people with dementia, according to researchers at Lancaster University.The &#

Updated on: February 26,2024

Music proves to be a real hit in dementia project

by Lancaster UniversityCreative activities, such as designing musical instruments, can improve the quality of life of people with dementia, according to researchers at Lancaster University.The &#

Updated on:February 26,2024

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on: April 02,2024

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on:April 02,2024

LATE: A common but largely unknown cause of dementia

by Andrew E. Budson,Harvard UniversityCredit: Pixabay/CC0 Public DomainIf dementia is a general term that means thinking and memory has deteriorated to the point that it interferes with day-to-d

Updated on: May 11,2024

LATE: A common but largely unknown cause of dementia

by Andrew E. Budson,Harvard UniversityCredit: Pixabay/CC0 Public DomainIf dementia is a general term that means thinking and memory has deteriorated to the point that it interferes with day-to-d

Updated on:May 11,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on: March 09,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on:March 09,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on: March 28,2024

Common degenerative brain disease may begin to develop already in middle age

byUniversity of HelsinkiImmunohistochemical staining with 5G4 antibody against alpha-synuclein in the Tampere Sudden Death Study cohort. Black arrowheads highlight LBs and gray arrowheads point

Updated on:March 28,2024

Ultrasound therapy shows promise as a treatment for Alzheimer's disease

by University of QueenslandGraphical representation of the findings of this study: Improved memory, enhanced functional connectivity and an altered proteome were found in APP23 mice in the absenc

Updated on: April 06,2024

Ultrasound therapy shows promise as a treatment for Alzheimer's disease

by University of QueenslandGraphical representation of the findings of this study: Improved memory, enhanced functional connectivity and an altered proteome were found in APP23 mice in the absenc

Updated on:April 06,2024