Big data initiative discovers new causal pathways in Alzheimer's

by King's College LondonFlowchart of study design. CTL, cognitively normal controls; MCI, mild cognitive impairment; AD, Alzheimer's disease; Aβ, β-amyloid; CSF, cerebrospinal fluid; A, a

Updated on: May 20,2024

Big data initiative discovers new causal pathways in Alzheimer's

by King's College LondonFlowchart of study design. CTL, cognitively normal controls; MCI, mild cognitive impairment; AD, Alzheimer's disease; Aβ, β-amyloid; CSF, cerebrospinal fluid; A, a

Updated on:May 20,2024

Successful or pathological cognitive aging? The 'frontal preservation, temporal impairment (FPTI)' hypothesis

by Science China PressThe SCA group has specific frontal preservation and the MCI group has specific temporal impairment on GM morphology, GM network, and WM network properties, in addition, the

Updated on: February 05,2024

Successful or pathological cognitive aging? The 'frontal preservation, temporal impairment (FPTI)' hypothesis

by Science China PressThe SCA group has specific frontal preservation and the MCI group has specific temporal impairment on GM morphology, GM network, and WM network properties, in addition, the

Updated on:February 05,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

Secondary infections inflame the brain, worsening cognition in Alzheimer's disease

by Trinity College DublinCredit: Unsplash/CC0 Public DomainNew research into Alzheimer's disease (AD) suggests that secondary infections and new inflammatory events amplify the brain's im

Updated on: June 20,2024

Secondary infections inflame the brain, worsening cognition in Alzheimer's disease

by Trinity College DublinCredit: Unsplash/CC0 Public DomainNew research into Alzheimer's disease (AD) suggests that secondary infections and new inflammatory events amplify the brain's im

Updated on:June 20,2024

Gene variant could protect against ultra-rare seizure disorder, fruit fly research finds

byUniversity of Utah Health SciencesFruit flies for research purposes in a vial in lab. Credit: Charlie Ehlert / University of Utah HealthOne in 10 Americans live with a rare disease, which ofte

Updated on: February 18,2025

Gene variant could protect against ultra-rare seizure disorder, fruit fly research finds

byUniversity of Utah Health SciencesFruit flies for research purposes in a vial in lab. Credit: Charlie Ehlert / University of Utah HealthOne in 10 Americans live with a rare disease, which ofte

Updated on:February 18,2025

Simple test could help predict risk of Alzheimer's disease 20 years in advance

by The Australian National Universitya) Sketch of protein translocation through a SiNx nanopore membrane. The proteins in a buffered electrolyte solution are placed in the cis and trans channels

Updated on: March 02,2024

Simple test could help predict risk of Alzheimer's disease 20 years in advance

by The Australian National Universitya) Sketch of protein translocation through a SiNx nanopore membrane. The proteins in a buffered electrolyte solution are placed in the cis and trans channels

Updated on:March 02,2024

Progranulin and dementia—a blood sample does not tell the full story!

by Bentham Science PublishersProgranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal

Updated on: March 07,2024

Progranulin and dementia—a blood sample does not tell the full story!

by Bentham Science PublishersProgranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal

Updated on:March 07,2024

Can online therapy reduce distress in dementia carers?

by University of ExeterCaring is both rewarding and demanding. Credit: University of ExeterA new study is inviting people who care for someone with dementia to help investigate whether an online

Updated on: March 09,2024

Can online therapy reduce distress in dementia carers?

by University of ExeterCaring is both rewarding and demanding. Credit: University of ExeterA new study is inviting people who care for someone with dementia to help investigate whether an online

Updated on:March 09,2024

Active mind, body may only do so much against Alzheimer's

(HealthDay)—There's plenty of evidence suggesting that people who are active socially, intellectually and physically may stave off Alzheimer's disease. However, a new study shows those efforts

Updated on: February 28,2024

Active mind, body may only do so much against Alzheimer's

(HealthDay)—There's plenty of evidence suggesting that people who are active socially, intellectually and physically may stave off Alzheimer's disease. However, a new study shows those efforts

Updated on:February 28,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on: March 07,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on:March 07,2024

Study identifies potential biomarker for Alzheimer's disease

by Boston University Medical CenterIn one of the largest studies to date to use metabolomics, the study of compounds that are created through various chemical reactions in the body, researchers h

Updated on: March 07,2024

Study identifies potential biomarker for Alzheimer's disease

by Boston University Medical CenterIn one of the largest studies to date to use metabolomics, the study of compounds that are created through various chemical reactions in the body, researchers h

Updated on:March 07,2024

Brain iron accumulation linked to cognitive decline in Alzheimer's patients

by Radiological Society of North AmericaR2? maps of healthy control participants and participants with Alzheimer disease. R2? maps are windowed between 10 and 50 sec21. Differences in iron concen

Updated on: April 10,2024

Brain iron accumulation linked to cognitive decline in Alzheimer's patients

by Radiological Society of North AmericaR2? maps of healthy control participants and participants with Alzheimer disease. R2? maps are windowed between 10 and 50 sec21. Differences in iron concen

Updated on:April 10,2024