Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on: March 30,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on:March 30,2024

Music proves to be a real hit in dementia project

by Lancaster UniversityCreative activities, such as designing musical instruments, can improve the quality of life of people with dementia, according to researchers at Lancaster University.The &#

Updated on: February 26,2024

Music proves to be a real hit in dementia project

by Lancaster UniversityCreative activities, such as designing musical instruments, can improve the quality of life of people with dementia, according to researchers at Lancaster University.The &#

Updated on:February 26,2024

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on: April 02,2024

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on:April 02,2024

LATE: A common but largely unknown cause of dementia

by Andrew E. Budson,Harvard UniversityCredit: Pixabay/CC0 Public DomainIf dementia is a general term that means thinking and memory has deteriorated to the point that it interferes with day-to-d

Updated on: May 11,2024

LATE: A common but largely unknown cause of dementia

by Andrew E. Budson,Harvard UniversityCredit: Pixabay/CC0 Public DomainIf dementia is a general term that means thinking and memory has deteriorated to the point that it interferes with day-to-d

Updated on:May 11,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Ultrasound therapy shows promise as a treatment for Alzheimer's disease

by University of QueenslandGraphical representation of the findings of this study: Improved memory, enhanced functional connectivity and an altered proteome were found in APP23 mice in the absenc

Updated on: April 06,2024

Ultrasound therapy shows promise as a treatment for Alzheimer's disease

by University of QueenslandGraphical representation of the findings of this study: Improved memory, enhanced functional connectivity and an altered proteome were found in APP23 mice in the absenc

Updated on:April 06,2024

How the brain remembers where you're going

by Julia Weiler, Donata Zuber,Ruhr-Universitaet-BochumCredit: CC0 Public DomainResearchers have made new discoveries about how certain brainwaves aid navigation. They hope that the methods may b

Updated on: May 18,2024

How the brain remembers where you're going

by Julia Weiler, Donata Zuber,Ruhr-Universitaet-BochumCredit: CC0 Public DomainResearchers have made new discoveries about how certain brainwaves aid navigation. They hope that the methods may b

Updated on:May 18,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024

New imaging method illuminates oxygen's journey in the brain

by University of Rochester Medical CenterLuminescent protein, substrate, and oxygen all combine to create chemical chain reaction to produce light. Images shows the cortex of a mouse recorded ove

Updated on: March 30,2024

New imaging method illuminates oxygen's journey in the brain

by University of Rochester Medical CenterLuminescent protein, substrate, and oxygen all combine to create chemical chain reaction to produce light. Images shows the cortex of a mouse recorded ove

Updated on:March 30,2024