A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on: March 02,2024

Poor metabolic health could increase risk of developing dementia later in life

by University of OxfordCredit: CC0 Public DomainResearchers at Oxford Population Health have found that having poor metabolic health was related to an increased risk of developing dementia in a s

Updated on:March 02,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on: May 13,2024

Most seniors with dementia live at home, despite pain, anxiety, poor health

by University of California, San FranciscoCredit: CC0 Public DomainContrary to popular belief, most older Americans with advancing dementia remain in their own homes—many until they die. But a ne

Updated on:May 13,2024

How common nutritional supplements may protect against traumatic brain injuries in sports

by Max Esterhuizen,Virginia TechCredit: Pixabay/CC0 Public DomainThe pouring rain and blustery wind gusts are brutal. The crowd is bone-chillingly cold, but they don't care.Their favorite fo

Updated on: February 05,2024

How common nutritional supplements may protect against traumatic brain injuries in sports

by Max Esterhuizen,Virginia TechCredit: Pixabay/CC0 Public DomainThe pouring rain and blustery wind gusts are brutal. The crowd is bone-chillingly cold, but they don't care.Their favorite fo

Updated on:February 05,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on: May 21,2024

Use of TNF alpha inhibitors in Crohn's disease associated with higher risk of MS

by Hillary Smith,University of KentuckyDr. Jay Avasarala, professor of neurology and director of UK’s Multiple Sclerosis Clinic, and co-authors, conducted a retrospective study in which they eva

Updated on:May 21,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on: May 13,2024

Largescale brain epigenetics study provides new insights into dementia

by University of ExeterCredit: Unsplash/CC0 Public DomainThe largest study of its kind has unveiled new insights into how genes are regulated in dementia, including discovering 84 new genes linke

Updated on:May 13,2024

Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on: April 20,2024

Alzheimer's missing link ID'd, answering what tips brain's decline

by Washington University School of MedicineIn Alzheimer's, amyloid clumps (blue) develop first in the brain, followed by tangles of the protein tau (red). Tau is associated with memory loss a

Updated on:April 20,2024

Brain circuit strength predicts a child's ability to understand numbers

by Society for NeuroscienceHippocampal-parietal functional circuits predict number sense training gains. Functional connectivity of the (A) left and (B) right hippocampus with the left intraparie

Updated on: February 21,2024

Brain circuit strength predicts a child's ability to understand numbers

by Society for NeuroscienceHippocampal-parietal functional circuits predict number sense training gains. Functional connectivity of the (A) left and (B) right hippocampus with the left intraparie

Updated on:February 21,2024

Preliminary study: Drug may be safe in those with mild cognitive impairment, mild dementia

by American Academy of NeurologyCredit: CC0 Public DomainA small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Al

Updated on: February 05,2024

Preliminary study: Drug may be safe in those with mild cognitive impairment, mild dementia

by American Academy of NeurologyCredit: CC0 Public DomainA small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Al

Updated on:February 05,2024

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy

byLudwig Maximilian University of MunichDiscriminatory power of tau binding and p-tau between pairs of groups. Credit:Alzheimer's & Dementia(2024). DOI:10.1002/alz.14185. htt

Updated on: September 23,2024

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy

byLudwig Maximilian University of MunichDiscriminatory power of tau binding and p-tau between pairs of groups. Credit:Alzheimer's & Dementia(2024). DOI:10.1002/alz.14185. htt

Updated on:September 23,2024