Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

How a tangled protein kills brain cells, promotes Alzheimer's

by Lisa Marshall,University of Colorado at BoulderGraphical abstract. Credit:Neuron(2021). DOI: 10.1016/j.neuron.2021.03.026Look deep inside the brain of someone with Alzheimer's

Updated on: July 04,2024

How a tangled protein kills brain cells, promotes Alzheimer's

by Lisa Marshall,University of Colorado at BoulderGraphical abstract. Credit:Neuron(2021). DOI: 10.1016/j.neuron.2021.03.026Look deep inside the brain of someone with Alzheimer's

Updated on:July 04,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

New mechanism by which Alzheimer's disease spreads through the brain discovered

by Linköping UniversityResearchers at Linköping University study how Alzheimer's disease spreads in the brain. Credit: Thor Balkhed/Linköping UniversityThe waste-management system of the cell

Updated on: April 16,2024

New mechanism by which Alzheimer's disease spreads through the brain discovered

by Linköping UniversityResearchers at Linköping University study how Alzheimer's disease spreads in the brain. Credit: Thor Balkhed/Linköping UniversityThe waste-management system of the cell

Updated on:April 16,2024

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on: June 20,2024

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on:June 20,2024

Successful or pathological cognitive aging? The 'frontal preservation, temporal impairment (FPTI)' hypothesis

by Science China PressThe SCA group has specific frontal preservation and the MCI group has specific temporal impairment on GM morphology, GM network, and WM network properties, in addition, the

Updated on: February 05,2024

Successful or pathological cognitive aging? The 'frontal preservation, temporal impairment (FPTI)' hypothesis

by Science China PressThe SCA group has specific frontal preservation and the MCI group has specific temporal impairment on GM morphology, GM network, and WM network properties, in addition, the

Updated on:February 05,2024

Uncovering the unusual way aggregates hijack proteins

by Utrecht University,Utrecht University Faculty of ScienceTau stacking. Credit: Stefan Rudiger - Utrecht UniversityUtrecht scientists have uncovered how aggregates alter the behavior of Tau pro

Updated on: July 01,2024

Uncovering the unusual way aggregates hijack proteins

by Utrecht University,Utrecht University Faculty of ScienceTau stacking. Credit: Stefan Rudiger - Utrecht UniversityUtrecht scientists have uncovered how aggregates alter the behavior of Tau pro

Updated on:July 01,2024

Study says Alzheimer's plaques can also affect the brain's blood vessels

by Bob Shepard,University of Alabama at Birmingham3-D microscope image of blood vessels (in red) with surrounding vascular amyloid plaques (in green). Credit: Ian KimbroughAmyloid beta, the plaq

Updated on: February 27,2024

Study says Alzheimer's plaques can also affect the brain's blood vessels

by Bob Shepard,University of Alabama at Birmingham3-D microscope image of blood vessels (in red) with surrounding vascular amyloid plaques (in green). Credit: Ian KimbroughAmyloid beta, the plaq

Updated on:February 27,2024

Brain iron accumulation linked to cognitive decline in Alzheimer's patients

by Radiological Society of North AmericaR2? maps of healthy control participants and participants with Alzheimer disease. R2? maps are windowed between 10 and 50 sec21. Differences in iron concen

Updated on: April 10,2024

Brain iron accumulation linked to cognitive decline in Alzheimer's patients

by Radiological Society of North AmericaR2? maps of healthy control participants and participants with Alzheimer disease. R2? maps are windowed between 10 and 50 sec21. Differences in iron concen

Updated on:April 10,2024

Can large fluid-filled spaces in the brain help identify those at risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainPeople with enlarged fluid-filled spaces in the brain around small blood vessels may be more likely to develop cognitive problems and deme

Updated on: May 18,2024

Can large fluid-filled spaces in the brain help identify those at risk of dementia?

by American Academy of NeurologyCredit: CC0 Public DomainPeople with enlarged fluid-filled spaces in the brain around small blood vessels may be more likely to develop cognitive problems and deme

Updated on:May 18,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on: March 07,2024

Clinicians should address needs of family caregivers of persons with dementia

by University of Pennsylvania School of NursingMore than 15 million family members and other unpaid caregivers provide care to persons living with dementia in the United States. Yet the current h

Updated on:March 07,2024

Simple diagnostic tool predicts individual risk of Alzheimer's

by Lund UniversityCredit: Pixabay/CC0 Public DomainResearchers at Lund University in Sweden have developed an algorithm that combines data from a simple blood test and brief memory tests, to pred

Updated on: June 20,2024

Simple diagnostic tool predicts individual risk of Alzheimer's

by Lund UniversityCredit: Pixabay/CC0 Public DomainResearchers at Lund University in Sweden have developed an algorithm that combines data from a simple blood test and brief memory tests, to pred

Updated on:June 20,2024