New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on: July 11,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on:July 11,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on: March 30,2024

A promising discovery in a rare neurodegenerative disease

by Katherine Gombay,McGill UniversityGene expression changes in SCA6 cerebellum at disease onset. (a) Timeline of disease progression in SCA6 mouse model. (b) Cerebellar vermis tissue was extrac

Updated on:March 30,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on: April 20,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on:April 20,2024

Music proves to be a real hit in dementia project

by Lancaster UniversityCreative activities, such as designing musical instruments, can improve the quality of life of people with dementia, according to researchers at Lancaster University.The &#

Updated on: February 26,2024

Music proves to be a real hit in dementia project

by Lancaster UniversityCreative activities, such as designing musical instruments, can improve the quality of life of people with dementia, according to researchers at Lancaster University.The &#

Updated on:February 26,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

How the brain remembers where you're going

by Julia Weiler, Donata Zuber,Ruhr-Universitaet-BochumCredit: CC0 Public DomainResearchers have made new discoveries about how certain brainwaves aid navigation. They hope that the methods may b

Updated on: May 18,2024

How the brain remembers where you're going

by Julia Weiler, Donata Zuber,Ruhr-Universitaet-BochumCredit: CC0 Public DomainResearchers have made new discoveries about how certain brainwaves aid navigation. They hope that the methods may b

Updated on:May 18,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on: March 13,2024

A 'low dose aspirin' for dementia? Drug ready for first in-human testing

by University of KentuckyLinda Van Eldik in her lab at the Sanders-Brown Center on Aging. Van Eldik's drug candidate, which might function as a sort of "low-dose aspirin" for the pr

Updated on:March 13,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on: March 07,2024

Prediction of conversion to Alzheimer's disease with longitudinal measures and time-to-event data

by IOS PressPredicting the timing of Alzheimer's disease (AD) conversion for individuals with mild cognitive impairment (MCI) can be significantly improved by incorporating longitudinal chang

Updated on:March 07,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on: March 28,2024

Novel method facilitates study of oxidized lipids involved in neurodegenerative diseases

NOVEMBER 15, 2023byFAPESPGraphical abstract. Credit:Free Radical Biology and Medicine(2023). DOI: 10.1016/j.freeradbiomed.2023.08.019Lipids are a diversified class of biomolecules wi

Updated on:March 28,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on: July 17,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on:July 17,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on: March 09,2024

Enzyme treatment of gene may reverse effects of Alzheimer's

by Tel Aviv UniversityFor the last 20 years, researchers have focused on amyloid beta peptides and the "plaque" they sprout in diseased brains as the main target of Alzheimer's rese

Updated on:March 09,2024

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on: April 02,2024

Seeing Alzheimer's disease

by University of MinnesotaCredit: University of MinnesotaWhat if we could diagnose early-stage Alzheimer's disease (AD) by looking into a person's eyes?A retinal scan technique, developed

Updated on:April 02,2024