Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on: March 02,2024

Midlife insomnia may increase risk for later dementia

by Lori SolomonInsomnia and short sleep duration in middle age increase the risk for dementia, according to a study published in the September issue ofAge and Ageing.Xiao Tan, from the Zhejiang

Updated on:March 02,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on: July 17,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on:July 17,2024

Dementia deaths rise during the summer of COVID, leading to concern

by Laurie Archbald-Pannone,The ConversationCredit: Unsplash/CC0 Public DomainDeaths from dementia during the summer of 2020 are nearly20% higherthan the number of dementia-related de

Updated on: March 19,2024

Dementia deaths rise during the summer of COVID, leading to concern

by Laurie Archbald-Pannone,The ConversationCredit: Unsplash/CC0 Public DomainDeaths from dementia during the summer of 2020 are nearly20% higherthan the number of dementia-related de

Updated on:March 19,2024

Research shortfall on common form of dementia highlighted

by University of ExeterJoan Grose had Lewy body dementia. Credit: University of ExeterNew research published inThe Lancethas highlighted the scarcity of evidence on the prognosis of d

Updated on: March 09,2024

Research shortfall on common form of dementia highlighted

by University of ExeterJoan Grose had Lewy body dementia. Credit: University of ExeterNew research published inThe Lancethas highlighted the scarcity of evidence on the prognosis of d

Updated on:March 09,2024

Study reveals how key brain regions regulate inhibitory actions, paving way for impulse control disorder treatment

by Juntendo University Research Promotion CenterExperiment overview. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54564-9A pioneering study from Japan meticulously maps the

Updated on: December 17,2024

Study reveals how key brain regions regulate inhibitory actions, paving way for impulse control disorder treatment

by Juntendo University Research Promotion CenterExperiment overview. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-54564-9A pioneering study from Japan meticulously maps the

Updated on:December 17,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on: April 20,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on:April 20,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on: February 05,2024

Overwhelmed? Your astrocytes can help with that

by University of California, San FranciscoDissection of astrocyte Ca2+and behavioral state. (a) Representative 2P mean projection image from one ten-minute recording of in vivo astrocyte Gc

Updated on:February 05,2024

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on: February 26,2024

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on:February 26,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on: April 07,2024

New imaging technique in Alzheimer's disease opens up possibilities for drug development

by Lund UniversityThe brain of an Alzheimer’s patient in a tau PET image. Red indicates the areas with the highest concentration of the tau protein. In the magnifying glass, a microscope enlargem

Updated on:April 07,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on: March 30,2024

FDA advisory panelist outlines issues with aducanumab's approval for Alzheimer's disease

by American College of PhysiciansPET scan of a human brain with Alzheimer's disease. Credit: public domainDespite near unanimous objection from its advisory panel, the U.S. Food and Drug Admi

Updated on:March 30,2024