Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

New imaging method illuminates oxygen's journey in the brain

by University of Rochester Medical CenterLuminescent protein, substrate, and oxygen all combine to create chemical chain reaction to produce light. Images shows the cortex of a mouse recorded ove

Updated on: March 30,2024

New imaging method illuminates oxygen's journey in the brain

by University of Rochester Medical CenterLuminescent protein, substrate, and oxygen all combine to create chemical chain reaction to produce light. Images shows the cortex of a mouse recorded ove

Updated on:March 30,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on: March 02,2024

Researchers show multiple sclerosis drug can be used as Alzheimer's therapy

by Lindsay Travis,University of KentuckyWorking model for the effect of ponesimod on microglial activation and phagocytosis. Aβ42 binds to TLR4 and induces a complex with S1PR1. S1P co-activates

Updated on:March 02,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on: July 17,2024

Study pinpoints origins of creativity in the brain

byUniversity of Utah Health SciencesElectrodes at multiple brain regions reveal brain activity in real time. Colored dots show the locations of all of the electrodes across all patients, color-c

Updated on:July 17,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on: April 10,2024

Alzheimer's disease can be diagnosed before symptoms emerge

by Lund UniversityNIA-AA versus IWG criteria. Differences in the nomenclature of cognitively unimpaired individuals with (+) or without (−) in vivo biomarker evidence of Aβ (A) and tau (T) pathol

Updated on:April 10,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on: February 26,2024

Swedish diagnostic method for Alzheimer's becomes international standard

by Krister Svahn,University of GothenburgResearchers at Gothenburg University have developed a reference method for standardized measurements that diagnose Alzheimer's disease decades before

Updated on:February 26,2024

Human brains are getting larger: That may be good news for dementia risk

byUC DavisHuman brain volume has increased for people born in the 1970s compared to the 1930s. Credit: UC Davis HealthA new study by researchers at UC Davis Health found human brains are getting

Updated on: March 28,2024

Human brains are getting larger: That may be good news for dementia risk

byUC DavisHuman brain volume has increased for people born in the 1970s compared to the 1930s. Credit: UC Davis HealthA new study by researchers at UC Davis Health found human brains are getting

Updated on:March 28,2024

Early lead exposure could result in memory issues later in life

Updated on: September 02,2025

Early lead exposure could result in memory issues later in life

Updated on:September 02,2025

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on: February 26,2024

Yeast protein could offer clues to how Alzheimer's plaques form in the brain

by Anne Trafton,Massachusetts Institute of TechnologyMIT biologists found that the yeast protein Rim4 forms disordered clumps similar to the beta-amyloid plaques associated with Alzheimer’s dise

Updated on:February 26,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on: April 08,2024

Alzheimer's disease and type 2 diabetes—hope for inhibitors against amyloid plaques

by Technical University MunichA new class of designed macrocyclic peptides has been developed which are highly potent inhibitors of amyloid plaque formation. Credit: Kapurniotu/ TUMEffective ther

Updated on:April 08,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on: July 11,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on:July 11,2024

Memory games: Eating well to remember

by University of Technology, SydneyCredit: CC0 Public DomainA healthy diet is essential to living well, but as we age, should we change what we eat?UTS research fellow Dr. Luna Xu has studied dat

Updated on: June 20,2024

Memory games: Eating well to remember

by University of Technology, SydneyCredit: CC0 Public DomainA healthy diet is essential to living well, but as we age, should we change what we eat?UTS research fellow Dr. Luna Xu has studied dat

Updated on:June 20,2024