New synapse type discovered through spatial proteomics

by Tamara Bäßler,Max Planck SocietyNeuronal atlas with 30 different protein types in spatial resolution, visualized with the new SUM-PAINT method. The detailed images illustrate the extremely hi

Updated on: March 30,2024 8

New synapse type discovered through spatial proteomics

by Tamara Bäßler,Max Planck SocietyNeuronal atlas with 30 different protein types in spatial resolution, visualized with the new SUM-PAINT method. The detailed images illustrate the extremely hi

Updated on:March 30,2024 8

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on: February 05,2024 13

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on:February 05,2024 13

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on: February 26,2024 11

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on:February 26,2024 11

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on: February 26,2024 17

Alzheimer's-disease-related proteases control axonal guidance by regulating growth cone dynamics

by VIB (the Flanders Institute for Biotechnology)Diagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.BACE1 is the major drug target for Alzheimer's

Updated on:February 26,2024 17

Unlocking Alzheimer's mysteries: A comprehensive brain connectome-based survey

by TranSpreadStructural connectivity (SC) refers to anatomical links and is usually estimated using fiber bundles derived from diffusion MRI; Functional connectivity (FC) and effective connectivity (E

Updated on: March 28,2024 0

Unlocking Alzheimer's mysteries: A comprehensive brain connectome-based survey

by TranSpreadStructural connectivity (SC) refers to anatomical links and is usually estimated using fiber bundles derived from diffusion MRI; Functional connectivity (FC) and effective connectivity (E

Updated on:March 28,2024 0

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on: April 16,2024 18

Leaders in Alzheimer's research herald the dawn of a new era in drug development based on biology of aging

by Alzheimer's Drug Discovery FoundationCredit: Pixabay/CC0 Public DomainA combination of drugs will be needed to effectively treat or prevent Alzheimer's disease and leading experts say we ha

Updated on:April 16,2024 18

Depression and dementia in the age of COVID-19

by Donald Weaver,The ConversationMore than half of patients with dementia also suffer from depression. If the depression remains untreated, the associated memory and cognitive problems worsen. C

Updated on: March 30,2024 16

Depression and dementia in the age of COVID-19

by Donald Weaver,The ConversationMore than half of patients with dementia also suffer from depression. If the depression remains untreated, the associated memory and cognitive problems worsen. C

Updated on:March 30,2024 16

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on: March 02,2024 19

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on:March 02,2024 19

Preliminary study: Drug may be safe in those with mild cognitive impairment, mild dementia

by American Academy of NeurologyCredit: CC0 Public DomainA small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Al

Updated on: February 05,2024 7

Preliminary study: Drug may be safe in those with mild cognitive impairment, mild dementia

by American Academy of NeurologyCredit: CC0 Public DomainA small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Al

Updated on:February 05,2024 7

Hospital patients with dementia and other causes of confusion 'have worse outcomes'

by University of StirlingProfessor Emma Reynish, Chair in Dementia Studies at the University of Stirling. Credit: University of StirlingHospital patients with dementia and other causes of confusi

Updated on: March 09,2024 16

Hospital patients with dementia and other causes of confusion 'have worse outcomes'

by University of StirlingProfessor Emma Reynish, Chair in Dementia Studies at the University of Stirling. Credit: University of StirlingHospital patients with dementia and other causes of confusi

Updated on:March 09,2024 16

Planning can help gun owners age safely

by University of WashingtonCredit: CC0 Public DomainThe Harborview Injury Prevention & Research Center (HIPRC) has created anew online resourceto help older adults with cognitive

Updated on: June 18,2024 8

Planning can help gun owners age safely

by University of WashingtonCredit: CC0 Public DomainThe Harborview Injury Prevention & Research Center (HIPRC) has created anew online resourceto help older adults with cognitive

Updated on:June 18,2024 8

Klotho-VS heterozygosity genotype linked to reduced alzheimer disease risk

(HealthDay)—Klotho-VS heterozygosity (KL-VSHET+status) is associated with a reduced risk for Alzheimer disease (AD) and β-amyloid (Aβ) burden in cognitively normal individuals aged older than 60

Updated on: March 30,2024 19

Klotho-VS heterozygosity genotype linked to reduced alzheimer disease risk

(HealthDay)—Klotho-VS heterozygosity (KL-VSHET+status) is associated with a reduced risk for Alzheimer disease (AD) and β-amyloid (Aβ) burden in cognitively normal individuals aged older than 60

Updated on:March 30,2024 19