Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on: October 21,2024 0

Promising Alzheimer's drug candidate prevents buildup of tau proteins in lab and fruit fly studies

byLancaster UniversityThe brain of a 7-day-old fruit fly with Tau expressed in a neuronal circuit used by the fly in olfactory memory. The green outlines the neurons, which are starting to swell

Updated on:October 21,2024 0

Flotillin is a novel diagnostic blood marker of Alzheimer's disease

by Nagoya City UniversityFlotillin in serum collected from patients with AD and non-AD cases was examined by western blot analysis. Intensity of flotillin bands was quantified using Image J. A, The re

Updated on: March 30,2024 10

Flotillin is a novel diagnostic blood marker of Alzheimer's disease

by Nagoya City UniversityFlotillin in serum collected from patients with AD and non-AD cases was examined by western blot analysis. Intensity of flotillin bands was quantified using Image J. A, The re

Updated on:March 30,2024 10

Preliminary study: Drug may be safe in those with mild cognitive impairment, mild dementia

by American Academy of NeurologyCredit: CC0 Public DomainA small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Al

Updated on: February 05,2024 7

Preliminary study: Drug may be safe in those with mild cognitive impairment, mild dementia

by American Academy of NeurologyCredit: CC0 Public DomainA small, preliminary study of an investigational new drug being studied for mild cognitive impairment and mild dementia associated with Al

Updated on:February 05,2024 7

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on: February 05,2024 13

Allopurinol may cut risk for neurodegenerative diseases

by Elana GotkineXanthine dehydrogenase/oxidase blockers may reduce the risk for neurodegenerative diseases, according to a study published online May 17 inPLOS ONE.Yizhe Song, from the Washingto

Updated on:February 05,2024 13

Virtual reality app offers unique glimpse into life with dementia

by Alzheimer's Research UKCredit: Alzheimer's Research UKAn innovative virtual reality smartphone app – "A Walk Through Dementia" – will launch at a three-day public installatio

Updated on: March 09,2024 18

Virtual reality app offers unique glimpse into life with dementia

by Alzheimer's Research UKCredit: Alzheimer's Research UKAn innovative virtual reality smartphone app – "A Walk Through Dementia" – will launch at a three-day public installatio

Updated on:March 09,2024 18

Intranasal insulin may have pro-cognitive benefits

by Elana GotkineIntranasal insulin (INI) seems to have a beneficial effect on global cognition among patients with Alzheimer's disease (AD)/mild cognitive impairment (MCI), according to a review p

Updated on: March 09,2024 10

Intranasal insulin may have pro-cognitive benefits

by Elana GotkineIntranasal insulin (INI) seems to have a beneficial effect on global cognition among patients with Alzheimer's disease (AD)/mild cognitive impairment (MCI), according to a review p

Updated on:March 09,2024 10

Can a calculator predict your risk of dementia?

by The Ottawa HospitalResearchers have built and validated an online calculator that empowers individuals 55 and over to better understand the health of their brain and how they can reduce their risk

Updated on: June 18,2024 5

Can a calculator predict your risk of dementia?

by The Ottawa HospitalResearchers have built and validated an online calculator that empowers individuals 55 and over to better understand the health of their brain and how they can reduce their risk

Updated on:June 18,2024 5

Curcumin for amyloidosis and lipid metabolism—a novel insight

by Shinshu UniversitySchematic diagram of the effect of curcumin mediated by PPARa pathway in AApoAII amyloidosis model mouse. Credit: Jian DaiCurcumin is a polyphenol compound produced by plants of t

Updated on: June 24,2024 5

Curcumin for amyloidosis and lipid metabolism—a novel insight

by Shinshu UniversitySchematic diagram of the effect of curcumin mediated by PPARa pathway in AApoAII amyloidosis model mouse. Credit: Jian DaiCurcumin is a polyphenol compound produced by plants of t

Updated on:June 24,2024 5

Bacteria in the nose may increase risk of Alzheimer's disease

by Griffith UniversitySchematics illustrating the process for quantifying the amount of viable infectious C. pneumoniae present in various mouse tissues. (A) Mice were first intranasally inoculat

Updated on: April 29,2024 20

Bacteria in the nose may increase risk of Alzheimer's disease

by Griffith UniversitySchematics illustrating the process for quantifying the amount of viable infectious C. pneumoniae present in various mouse tissues. (A) Mice were first intranasally inoculat

Updated on:April 29,2024 20

Imaging technique shows Alzheimer's disease progress

by Wiebe Van Der Veen,University of TwenteThe high-lighted squares (left) are the 30 by 30 micron areas in the middle and right images (upper: plaque, lower: tangle). Credit: Univers

Updated on: May 06,2024 14

Imaging technique shows Alzheimer's disease progress

by Wiebe Van Der Veen,University of TwenteThe high-lighted squares (left) are the 30 by 30 micron areas in the middle and right images (upper: plaque, lower: tangle). Credit: Univers

Updated on:May 06,2024 14

Understanding removal of brain fluid provides avenue for Alzheimer's treatment

by Alzheimer's Research UKResearchers in Switzerland have investigated the way fluid is removed from around the brain. Finding a new pathway for its removal, their work may signal a paradigm

Updated on: March 07,2024 11

Understanding removal of brain fluid provides avenue for Alzheimer's treatment

by Alzheimer's Research UKResearchers in Switzerland have investigated the way fluid is removed from around the brain. Finding a new pathway for its removal, their work may signal a paradigm

Updated on:March 07,2024 11

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024 20

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024 20