Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on: March 28,2024

Movement disorder ALS and cognitive disorder FTLD show strong molecular overlaps, new study shows

byMassachusetts Institute of TechnologyStained motor cortex tissue from a donor with ALS (right) shows reduced amounts of the protein HLA-E (green) in the vasculature. HLA-E is thought to inhibi

Updated on:March 28,2024

Forecasting method may help people with epilepsy predict their seizures

byUniversity of California, San FranciscoMapping network connectivity to cycles of seizure likelihood. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03149-6A team of epilepsy

Updated on: July 31,2024

Forecasting method may help people with epilepsy predict their seizures

byUniversity of California, San FranciscoMapping network connectivity to cycles of seizure likelihood. Credit:Nature Medicine(2024). DOI: 10.1038/s41591-024-03149-6A team of epilepsy

Updated on:July 31,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on: July 17,2024

Accurate and continuous remote monitoring of step length can be sensitive marker for neurological diseases and aging

byTel-Aviv UniversityA person walking in a state-of-the-art gait lab, with a wearable sensor positioned on his lower back. He is walking over a gait mat embedded with force-sensitive sensors. Th

Updated on:July 17,2024

Excess body fat tied to lower cognitive scores in adults

(HealthDay)—Both generalized and visceral adiposity are associated with lower cognitive scores throughout midlife, according to a study published online Feb. 1 inJAMA Network Open.Sonia S. Anand

Updated on: February 05,2024

Excess body fat tied to lower cognitive scores in adults

(HealthDay)—Both generalized and visceral adiposity are associated with lower cognitive scores throughout midlife, according to a study published online Feb. 1 inJAMA Network Open.Sonia S. Anand

Updated on:February 05,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on: March 02,2024

Both high and low HDL cholesterol tied to increased risk of dementia

by American Academy of NeurologyCredit: CC0 Public DomainHaving either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increa

Updated on:March 02,2024

Residence in disadvantaged neighborhoods increases dementia risk

by Elana GotkineFor older veterans, residence within more disadvantaged neighborhoods is associated with an increased risk for dementia, according to a study published online July 19 inJAMA Neur

Updated on: July 04,2024

Residence in disadvantaged neighborhoods increases dementia risk

by Elana GotkineFor older veterans, residence within more disadvantaged neighborhoods is associated with an increased risk for dementia, according to a study published online July 19 inJAMA Neur

Updated on:July 04,2024

Older Americans' finances decline in years before dementia diagnosis

by Ernie MundellPerhaps succumbing to fraudsters or facing mounting bills, older Americans begin losing wealth in the years preceding a definitive dementia diagnosis, new research shows.For example, t

Updated on: March 02,2024

Older Americans' finances decline in years before dementia diagnosis

by Ernie MundellPerhaps succumbing to fraudsters or facing mounting bills, older Americans begin losing wealth in the years preceding a definitive dementia diagnosis, new research shows.For example, t

Updated on:March 02,2024

Progranulin and dementia—a blood sample does not tell the full story!

by Bentham Science PublishersProgranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal

Updated on: March 07,2024

Progranulin and dementia—a blood sample does not tell the full story!

by Bentham Science PublishersProgranulin is a central protein in both neuronal survival and neurodegenerative diseases. It is thus not surprising that altered progranulin levels represent a universal

Updated on:March 07,2024

New synapse type discovered through spatial proteomics

by Tamara Bäßler,Max Planck SocietyNeuronal atlas with 30 different protein types in spatial resolution, visualized with the new SUM-PAINT method. The detailed images illustrate the extremely hi

Updated on: March 30,2024

New synapse type discovered through spatial proteomics

by Tamara Bäßler,Max Planck SocietyNeuronal atlas with 30 different protein types in spatial resolution, visualized with the new SUM-PAINT method. The detailed images illustrate the extremely hi

Updated on:March 30,2024

Salt-seeking behavior traced to specific brain neurons

byUniversity of IowaCredit: Pixabay/CC0 Public DomainSalt, or more precisely the sodium it contains, is very much a "Goldilocks" nutrient. Low sodium levels cause a drop in blood volum

Updated on: January 19,2025

Salt-seeking behavior traced to specific brain neurons

byUniversity of IowaCredit: Pixabay/CC0 Public DomainSalt, or more precisely the sodium it contains, is very much a "Goldilocks" nutrient. Low sodium levels cause a drop in blood volum

Updated on:January 19,2025

Cutting-edge treatment approach addresses neurobehavioral symptoms in neurofibromatosis type 1

Updated on: August 07,2025

Cutting-edge treatment approach addresses neurobehavioral symptoms in neurofibromatosis type 1

Updated on:August 07,2025