Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on: November 07,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on:November 07,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Secondary infections inflame the brain, worsening cognition in Alzheimer's disease

by Trinity College DublinCredit: Unsplash/CC0 Public DomainNew research into Alzheimer's disease (AD) suggests that secondary infections and new inflammatory events amplify the brain's im

Updated on: June 20,2024

Secondary infections inflame the brain, worsening cognition in Alzheimer's disease

by Trinity College DublinCredit: Unsplash/CC0 Public DomainNew research into Alzheimer's disease (AD) suggests that secondary infections and new inflammatory events amplify the brain's im

Updated on:June 20,2024

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on: June 20,2024

Simple molecular reagents to treat Alzheimer's disease

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of a rational strategy for designing compact aromatic molecules with multiple reactivities against pathological factors f

Updated on:June 20,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on: April 20,2024

Alzheimer's risk gene impairs development of new neurons in mice

by Society for NeuroscienceApoE-expressing astrocytes (green) interacting with tdTomato-expressing dendrites (red) from adult newborn hippocampal neurons. Credit: Tensaouti et al.,eNeuro&nb

Updated on:April 20,2024

Team reports major breakthrough in understanding Alzheimer's disease

by Trinity College DublinA human donor Alzheimer's disease brain tissue stained with an agent called 'congo-red', which allows for the visualization of amyloid-beta plaques (red) in t

Updated on: February 26,2024

Team reports major breakthrough in understanding Alzheimer's disease

by Trinity College DublinA human donor Alzheimer's disease brain tissue stained with an agent called 'congo-red', which allows for the visualization of amyloid-beta plaques (red) in t

Updated on:February 26,2024

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on: April 28,2025

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on:April 28,2025

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on: November 28,2024

PNA5 protein shows potential for treating Parkinson's-related cognitive decline and dementia

byUniversity of ArizonaPNA5 blunts neuronal cell loss in the hippocampus. Credit:Experimental Neurology(2024). DOI: 10.1016/j.expneurol.2024.114926A recently published study by resea

Updated on:November 28,2024

New research uncovers brain changes in Parkinson's disease

Updated on: March 09,2025

New research uncovers brain changes in Parkinson's disease

Updated on:March 09,2025

Scientists reveal chemical structural analysis in neural computations that allow us to identify odors

byChinese Academy of SciencesNostril-specific modulation of odor perception by substructure adaptation. Credit:Nature Human Behaviour(2024). DOI: 10.1038/s41562-024-01849-0Scents, su

Updated on: March 28,2024

Scientists reveal chemical structural analysis in neural computations that allow us to identify odors

byChinese Academy of SciencesNostril-specific modulation of odor perception by substructure adaptation. Credit:Nature Human Behaviour(2024). DOI: 10.1038/s41562-024-01849-0Scents, su

Updated on:March 28,2024