Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on: September 06,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on:September 06,2024

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on: February 26,2024

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on:February 26,2024

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on: March 09,2024

The role of verb fluency in the detection of early cognitive impairment in Alzheimer's disease

by IOS PressVerb fluency score. Credit: Memory Clinic and Research Center of Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, SpainThe ability to generate spoken verbs in infi

Updated on:March 09,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on: May 18,2024

Early accumulation of tau in the brain predicts memory decline in Alzheimer's disease

by Karolinska InstitutetHigh accumulation of tau in the brain measured by a PET scanner was the only biomarker that could predict cognitive decline in healthy individuals, people with mild cognit

Updated on:May 18,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on: July 11,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on:July 11,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on: February 05,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on:February 05,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on: March 09,2024

Alzheimer's patients are more often hospitalized after initiating antibiotic use

by University of Eastern FinlandCredit: CC0 Public DomainPeople with Alzheimer's disease (AD) are more often hospitalized after antibiotic initiation than people without AD, a new study from

Updated on:March 09,2024

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on: April 28,2025

'Healthy' vitamin B12 levels not enough to ward off neuro decline: Experts call for new recommendations for older

Updated on:April 28,2025

Midlife diet could help you eat your way to a healthy brain

by Deakin UniversityCredit: Wikipedia.People who eat a healthy diet during middle age have a larger brain volume than those with less healthy diets, new research reveals, suggesting food choices

Updated on: March 09,2024

Midlife diet could help you eat your way to a healthy brain

by Deakin UniversityCredit: Wikipedia.People who eat a healthy diet during middle age have a larger brain volume than those with less healthy diets, new research reveals, suggesting food choices

Updated on:March 09,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024