Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

Researchers develop combined data model to better evaluate for mild cognitive impairment

by Boston University School of MedicineA new study has shown that by combining imaging and neuropsychological testing, one can more accurately assess the cognitive status of individuals.Cognitive

Updated on: March 07,2024

Researchers develop combined data model to better evaluate for mild cognitive impairment

by Boston University School of MedicineA new study has shown that by combining imaging and neuropsychological testing, one can more accurately assess the cognitive status of individuals.Cognitive

Updated on:March 07,2024

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on: March 02,2024

Researchers create a new window on leading genetic cause of Alzheimer's

by Pacific Northwest National LaboratoryWorkflow for molecular characterization of CSF-Lps.Lipoproteins are exchange labeled with a rhodamine-containing phospholipid and size distribution determi

Updated on:March 02,2024

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on: February 26,2024

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on:February 26,2024

Team reports major breakthrough in understanding Alzheimer's disease

by Trinity College DublinA human donor Alzheimer's disease brain tissue stained with an agent called 'congo-red', which allows for the visualization of amyloid-beta plaques (red) in t

Updated on: February 26,2024

Team reports major breakthrough in understanding Alzheimer's disease

by Trinity College DublinA human donor Alzheimer's disease brain tissue stained with an agent called 'congo-red', which allows for the visualization of amyloid-beta plaques (red) in t

Updated on:February 26,2024

Minimally invasive neural interface allows brain access without skull opening

byRice UniversityEndocisternal neural interface in human and sheep models. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s41551-024-01281-9A team of researchers led by Ric

Updated on: November 28,2024

Minimally invasive neural interface allows brain access without skull opening

byRice UniversityEndocisternal neural interface in human and sheep models. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s41551-024-01281-9A team of researchers led by Ric

Updated on:November 28,2024

Bodybuilding supplement may help stave off progression of Alzheimer's

by Rush University Medical CenterGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112717RUSH researchers recently discovered that a muscle-building supplement

Updated on: June 24,2024

Bodybuilding supplement may help stave off progression of Alzheimer's

by Rush University Medical CenterGraphical abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.112717RUSH researchers recently discovered that a muscle-building supplement

Updated on:June 24,2024

Aerobic exercise training linked to enhanced brain function

by IOS PressRepresentative brain glucose metabolism scan from a participant in the usual low level of physical activity group (left) and from a participant in the moderate intensity aerobic train

Updated on: March 09,2024

Aerobic exercise training linked to enhanced brain function

by IOS PressRepresentative brain glucose metabolism scan from a participant in the usual low level of physical activity group (left) and from a participant in the moderate intensity aerobic train

Updated on:March 09,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on: February 28,2024

Dysfunctional endosomes are early sign of neurodegeneration

by University of California - San DiegoFalse-colored scanning electron micrograph of a human neuron. Credit: Image courtesy of Thomas Deerinck, NCMIR, UC San Diego.Writing in the April 11 issue o

Updated on:February 28,2024

Scientists discover a trigger of Alzheimer's disease

by Lomonosov Moscow State UniversityThree-dimensional structure of the dimer of the metal-binding domain of beta-amyloid peptide having 'English mutation'. Two peptide molecules connected

Updated on: February 28,2024

Scientists discover a trigger of Alzheimer's disease

by Lomonosov Moscow State UniversityThree-dimensional structure of the dimer of the metal-binding domain of beta-amyloid peptide having 'English mutation'. Two peptide molecules connected

Updated on:February 28,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on: July 01,2024

Untangling the role of tau in Alzheimer's disease

by Dani Ellenby, Okinawa Institute of Science and Technology Graduate UniversityWild-type (WT) h-tau loaded in presynaptic terminals inhibited excitatory synaptic transmission. Credit: Tetsuya Hori et

Updated on:July 01,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on: February 05,2024

Innovative AI solution to classify epileptic seizures

by Carnegie Mellon Portugal ProgramExamples of detection and crop, when the bed and the patient were properly detected, surrounding scenery removed, with enough space left to capture the full scale of

Updated on:February 05,2024