New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on: July 11,2024

New discovery could help treat a rare and severe form of amyloidosis

byWileyPET scan of a human brain with Alzheimer's disease. Credit: public domainIn people with a rare condition called light chain amyloidosis, light chain proteins—which are a component of

Updated on:July 11,2024

Uncovering one of the driving forces of Alzheimer's disease

by Flinders UniversityCredit: Pixabay/CC0 Public DomainAlzheimer's disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understand

Updated on: July 01,2024

Uncovering one of the driving forces of Alzheimer's disease

by Flinders UniversityCredit: Pixabay/CC0 Public DomainAlzheimer's disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understand

Updated on:July 01,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on: September 06,2024

Prioritizing the unexpected: New brain mechanism uncovered

bySainsbury Wellcome CentreNeurons in the mouse visual cortex with VIP neurons in magenta. Credit: Sainsbury Wellcome CentreResearchers have discovered how two brain areas, the neocortex and the

Updated on:September 06,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on: August 03,2024

Researchers identify the 'broken gate' causing unstoppable brain signals in severe childhood epilepsy

by Florey Institute of Neuroscience and Mental Health2D transmembrane topology of the wild-type (WT) Nav1.2 channel showing 27 domains DI−DIV and amino acid residues N1662 (cytosolic side of S5DIV) an

Updated on:August 03,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on: February 28,2024

Neuronal heparan sulfates play role in amyloid pathology

(HealthDay)—Neuronal heparan sulfates (HSs) modulate brain amyloid-β (Aβ) clearance and aggregation in a mouse model of Alzheimer's disease (AD), according to an experimental study published in th

Updated on:February 28,2024

Study hints at ways to generate new neurons in old brains

byStanford University Medical CenterCredit: CC0 Public DomainMost neurons in the human brain last a lifetime, and for good reason. Intricate, long-term information is preserved in the complex st

Updated on: October 18,2024

Study hints at ways to generate new neurons in old brains

byStanford University Medical CenterCredit: CC0 Public DomainMost neurons in the human brain last a lifetime, and for good reason. Intricate, long-term information is preserved in the complex st

Updated on:October 18,2024

Autism study reveals pivotal role of neuronal protein CPEB4 condensates

byInstitute for Research in Biomedicine (IRB Barcelona)From left to right: Drs. Mendez, Bartomeu, Salvatella & Garcia Cabau. Credit: IRB BarcelonaAutism is a neurodevelopmental disorder char

Updated on: December 17,2024

Autism study reveals pivotal role of neuronal protein CPEB4 condensates

byInstitute for Research in Biomedicine (IRB Barcelona)From left to right: Drs. Mendez, Bartomeu, Salvatella & Garcia Cabau. Credit: IRB BarcelonaAutism is a neurodevelopmental disorder char

Updated on:December 17,2024

GSA's KAER toolkit promotes care conversations on brain health, cognitive status

by The Gerontological Society of AmericaCredit: Pixabay/CC0 Public DomainThe Gerontological Society of America (GSA) has released a new edition of its KAER toolkit, which is intended to support primar

Updated on: March 30,2024

GSA's KAER toolkit promotes care conversations on brain health, cognitive status

by The Gerontological Society of AmericaCredit: Pixabay/CC0 Public DomainThe Gerontological Society of America (GSA) has released a new edition of its KAER toolkit, which is intended to support primar

Updated on:March 30,2024

Research highlights misdiagnosis for people with Alzheimer's disease

by Alzheimer's Research UKResearch presented today (Tuesday 26 July) at the Alzheimer's Association International Conference 2016 suggests that men with Alzheimer's may be more likely

Updated on: March 07,2024

Research highlights misdiagnosis for people with Alzheimer's disease

by Alzheimer's Research UKResearch presented today (Tuesday 26 July) at the Alzheimer's Association International Conference 2016 suggests that men with Alzheimer's may be more likely

Updated on:March 07,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on: March 07,2024

An anti-apoE4 specific monoclonal antibody counteracts the pathological effects of apoE4 in vivo

by Bentham Science PublishersThe pathological hallmarks of Alzheimer's disease (AD), viz defective Aβ and tau proteins, have been the center of AD-directed therapeutic studies. Although this appro

Updated on:March 07,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on: September 06,2024

How zebrafish map their environment: Spatial orientation mechanisms surprisingly similar to our own

by Sophia Jahns, Max Planck Institute for Biological CyberneticsIdentification of PCs in the larval zebrafish brain. Credit:Nature(2024). DOI: 10.1038/s41586-024-07867-2Researchers are tur

Updated on:September 06,2024