Scientists discover a trigger of Alzheimer's disease

by Lomonosov Moscow State UniversityThree-dimensional structure of the dimer of the metal-binding domain of beta-amyloid peptide having 'English mutation'. Two peptide molecules connected

Updated on: February 28,2024

Scientists discover a trigger of Alzheimer's disease

by Lomonosov Moscow State UniversityThree-dimensional structure of the dimer of the metal-binding domain of beta-amyloid peptide having 'English mutation'. Two peptide molecules connected

Updated on:February 28,2024

Imaging technique shows Alzheimer's disease progress

by Wiebe Van Der Veen,University of TwenteThe high-lighted squares (left) are the 30 by 30 micron areas in the middle and right images (upper: plaque, lower: tangle). Credit: Univers

Updated on: May 06,2024

Imaging technique shows Alzheimer's disease progress

by Wiebe Van Der Veen,University of TwenteThe high-lighted squares (left) are the 30 by 30 micron areas in the middle and right images (upper: plaque, lower: tangle). Credit: Univers

Updated on:May 06,2024

Using tau imaging as diagnostic marker for Alzheimer disease

by The JAMA Network JournalsThe accumulation of β-Amyloid (Αβ) and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tra

Updated on: March 07,2024

Using tau imaging as diagnostic marker for Alzheimer disease

by The JAMA Network JournalsThe accumulation of β-Amyloid (Αβ) and tau proteins in the brain is hallmark pathology for Alzheimer disease. Recently developed positron emission tomography (PET) tra

Updated on:March 07,2024

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on: March 02,2024

Study reports on contributions to white matter injury in Alzheimer's disease

by Impact Journals LLCA vicious cycle generating WM injury driven by mixed vascular and ADNC in the aging human white matter. Diagnostic challenges for IHC and neuroimaging. Credit:Aging(2

Updated on:March 02,2024

Biochemical clues may predict who develops Alzheimer's disease—and who doesn't

by ElsevierDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Investigators have wondered why the brains of some cognitively-intact elderly individuals

Updated on: February 27,2024

Biochemical clues may predict who develops Alzheimer's disease—and who doesn't

by ElsevierDiagram of the brain of a person with Alzheimer's Disease. Credit: Wikipedia/public domain.Investigators have wondered why the brains of some cognitively-intact elderly individuals

Updated on:February 27,2024

Four tips to help your loved one with dementia enjoy the festive season

by Nikki-Anne Wilson,The ConversationCredit: Pixabay/CC0 Public DomainThe festive season is fast approaching, and if you're organizing celebrations with family or friends, you might be grapp

Updated on: February 24,2024

Four tips to help your loved one with dementia enjoy the festive season

by Nikki-Anne Wilson,The ConversationCredit: Pixabay/CC0 Public DomainThe festive season is fast approaching, and if you're organizing celebrations with family or friends, you might be grapp

Updated on:February 24,2024

Successful or pathological cognitive aging? The 'frontal preservation, temporal impairment (FPTI)' hypothesis

by Science China PressThe SCA group has specific frontal preservation and the MCI group has specific temporal impairment on GM morphology, GM network, and WM network properties, in addition, the

Updated on: February 05,2024

Successful or pathological cognitive aging? The 'frontal preservation, temporal impairment (FPTI)' hypothesis

by Science China PressThe SCA group has specific frontal preservation and the MCI group has specific temporal impairment on GM morphology, GM network, and WM network properties, in addition, the

Updated on:February 05,2024

New neurons form in the brain into the tenth decade of life, even in people with Alzheimer's

by Jacqueline Carey,University of Illinois at ChicagoNew neurons continue to be formed in the hippocampus into the tenth decade of life, even in people with mild cognitive impairment and Alzheim

Updated on: June 18,2024

New neurons form in the brain into the tenth decade of life, even in people with Alzheimer's

by Jacqueline Carey,University of Illinois at ChicagoNew neurons continue to be formed in the hippocampus into the tenth decade of life, even in people with mild cognitive impairment and Alzheim

Updated on:June 18,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on: March 02,2024

Reimagining preclinical trials: Marmosets as model systems for the study of Alzheimer's disease

by University of PittsburghMarmoset models bridge the current translation gap between human studies and cell and rodent models of AD. Establishment of marmoset models of aging and genetic risk lo

Updated on:March 02,2024

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on: February 26,2024

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on:February 26,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on: November 07,2024

Brain organoids reveal autism biology and potential treatments

byThe Scripps Research InstituteA cerebral organoid showing rosettes (or whirls) of newly developing and migrating new neurons (shown in purplish-red). Credit: Scripps ResearchUsing stem cells g

Updated on:November 07,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on: April 16,2024

Alzheimer's research—intracellular calcium store malfunction leads to brain hyperactivity

by Universitaet TübingenAmyloid proteins (plaques, blue) in the cerebral cortex of a mouse model of Alzheimer’s disease, surrounded by cortical immune cells (microglia, green). Activated microgli

Updated on:April 16,2024