Brain discovery holds key to boosting body's ability to fight Alzheimer's, multiple sclerosis

by University of VirginiaGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.09.030UVA Health researchers have discovered a molecule in the brain responsible for orchestra

Updated on: February 21,2024

Brain discovery holds key to boosting body's ability to fight Alzheimer's, multiple sclerosis

by University of VirginiaGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.09.030UVA Health researchers have discovered a molecule in the brain responsible for orchestra

Updated on:February 21,2024

The evolution of amyloid toxicity in Alzheimer's

by Biophysical SocietyThe suspected molecular dagger in Alzheimer's, shown here in red attacking cells (grey), contains a special twist. Credit: MaitiA tiny protein known as an "amyloid beta&

Updated on: February 28,2024

The evolution of amyloid toxicity in Alzheimer's

by Biophysical SocietyThe suspected molecular dagger in Alzheimer's, shown here in red attacking cells (grey), contains a special twist. Credit: MaitiA tiny protein known as an "amyloid beta&

Updated on:February 28,2024

Vitamin C deficiency and mitochondrial dysfunction in Alzheimer's disease

by Gabrielle Rushing,Vanderbilt UniversityEarly clinical features of sporadic Alzheimer's disease include alterations in mitochondrial functionthat appearprior to classical featu

Updated on: March 07,2024

Vitamin C deficiency and mitochondrial dysfunction in Alzheimer's disease

by Gabrielle Rushing,Vanderbilt UniversityEarly clinical features of sporadic Alzheimer's disease include alterations in mitochondrial functionthat appearprior to classical featu

Updated on:March 07,2024

Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on: August 08,2024

Researchers determine how the hippocampus generates and sustains oscillations

byRIKENA fluorescence micrograph of a CA1 in a mouse’s hippocampus. RIKEN researchers silenced the pyramidal cells in this region. Credit: Adapted fromNature Communications(2024). DO

Updated on:August 08,2024

Taking proton pump inhibitors not linked to higher dementia risk

by American Geriatrics SocietyProton pump inhibitors (PPIs) are medicines commonly prescribed to treat acid-related digestive problems, including gastroesophageal reflux disease (or GERD). As of

Updated on: March 07,2024

Taking proton pump inhibitors not linked to higher dementia risk

by American Geriatrics SocietyProton pump inhibitors (PPIs) are medicines commonly prescribed to treat acid-related digestive problems, including gastroesophageal reflux disease (or GERD). As of

Updated on:March 07,2024

Dementia creates listening issues in quiet, noisy environments

by Acoustical Society of AmericaCredit: CC0 Public DomainListening to the spoken word in noisy environments is challenging for everyone. Acoustic studies show people with mild dementia struggle t

Updated on: May 09,2024

Dementia creates listening issues in quiet, noisy environments

by Acoustical Society of AmericaCredit: CC0 Public DomainListening to the spoken word in noisy environments is challenging for everyone. Acoustic studies show people with mild dementia struggle t

Updated on:May 09,2024

Brain blood flow resistance more common in older adults with cognitive problems

byAmerican Physiological SocietyComparisons of cerebrovascular impedance coherence (top) and modulus (Z, bottom) between cognitive normal subjects (CN) and patients with amnestic mild cognitive

Updated on: November 05,2024

Brain blood flow resistance more common in older adults with cognitive problems

byAmerican Physiological SocietyComparisons of cerebrovascular impedance coherence (top) and modulus (Z, bottom) between cognitive normal subjects (CN) and patients with amnestic mild cognitive

Updated on:November 05,2024

Does persistent pain impact older adults' physical function, cognition, and well-being?

by WileyCredit: Unsplash/CC0 Public DomainIn a study in theJournal of the American Geriatrics Societyof 5,589 US adults aged 65 years and older, persistent pain was common and was lin

Updated on: February 05,2024

Does persistent pain impact older adults' physical function, cognition, and well-being?

by WileyCredit: Unsplash/CC0 Public DomainIn a study in theJournal of the American Geriatrics Societyof 5,589 US adults aged 65 years and older, persistent pain was common and was lin

Updated on:February 05,2024

Scientists discover a trigger of Alzheimer's disease

by Lomonosov Moscow State UniversityThree-dimensional structure of the dimer of the metal-binding domain of beta-amyloid peptide having 'English mutation'. Two peptide molecules connected

Updated on: February 28,2024

Scientists discover a trigger of Alzheimer's disease

by Lomonosov Moscow State UniversityThree-dimensional structure of the dimer of the metal-binding domain of beta-amyloid peptide having 'English mutation'. Two peptide molecules connected

Updated on:February 28,2024

Effects of type 2 diabetes are major risk to development of Alzheimer's disease

by Osaka City UniversityIncreased levels of blood glucose (green) after food intake trigger insulin (blue) secretion from islet β cells. This glucose-triggered insulin secretion is accompanied wi

Updated on: March 13,2024

Effects of type 2 diabetes are major risk to development of Alzheimer's disease

by Osaka City UniversityIncreased levels of blood glucose (green) after food intake trigger insulin (blue) secretion from islet β cells. This glucose-triggered insulin secretion is accompanied wi

Updated on:March 13,2024

Scientists discover new receptor for nerve growth factor—a promising target for treating pain

byNew York UniversityNerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Credit: Bunnett LabResearchers at the NYU Pain

Updated on: December 19,2024

Scientists discover new receptor for nerve growth factor—a promising target for treating pain

byNew York UniversityNerve growth factor receptor TrkA (in green) and co-receptor NRP1 (in purple) are coexpressed in the same nerve cells in mice. Credit: Bunnett LabResearchers at the NYU Pain

Updated on:December 19,2024

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on: February 26,2024

New genetic risk marker for late-life depression

by ElsevierOne of the most powerful predictors in neuropsychiatry is the epsilon 4 (ε4) allele of the apolipoprotein gene (APOE).Individuals who carry this ε4 variant of APOE are at increased ris

Updated on:February 26,2024